I'm 7 years clean, my wife is 6 years clean. I've been held hostage, lost my son to the ministry, lost the cars, the house, the money, the business, my wife left to a life on the street where she spent 18 months escaping extreme domestic and gang violence. She ended up pregnant and clawed her way out, she had to escape for two now. we spent 5 years apart healing in recovery. we've been back together for 2 years now and after losing all, today, we closed on a home. I run this podcast full time thanks to a bunch of great organizations in my community. I have a life I never saw coming. its possible. It's an epic adventure. We can recover.

I've been a functioning user for over 20 years. I don't fit the stereotype often associated with users. I have a great relationship with my family, and my partner and I have been happily together for over five years. I have a well-paying career that I genuinely enjoy. Despite this, I've reached a point where I no longer enjoy using, and I've wanted to quit for a long time. I use to maintain. I use because when i dont use, i have no motivation, no drive. I'm an addict and I always felt that as long as im a good person, treat others with respect, love my family and friends, and do no harm to others, why stop. It wasn't until I watched this video that I seriously considered stopping. Although my health should have been a compelling reason to quit, it wasn't enough until now. Thank you for this video. I really hope I haven't caused too much damage.

Smoked meth once, the rush was undescribable, felt invisible, nothing in the world matterd to me and wanting to do crazy shit. Crash was horrible and I wanted more , was craving that shit for weeks if not months. This drug is pure evil, decided not to do it again and happy with my decision.

Take this from someone who done meth the last 22 days and been awake the last 3. It’s not fun. I’m laying here watching shadows shoot everywhere thinking I’m seeing ghost. The on a comedown and it’s horrible. I just want to go to sleep and wake back as the real me again. I’m so mad at myself for doing the things I’ve done. I been hallucinating the past two days. I’m beyond sleep deprived and malnourished for the binge. I’m glad it was my last time

I did meth like 7 years ago by accident (was supposed to be adderall) and I still think about the experiences I had with it almost everyday. I think it leaves a permanent mark on your neurochemistry. I took it orally, so it's not like I smoked or injected it, but even then the "rush" or come-up right when the dose is hitting your brain is just unpronounceably amazing. It's close to if not the most extreme feeling of sheer euphoria the human brain is capable of producing. It feels very, very, "red", if that makes sense. Just vibrating red with tingly pleasure head to toe, eyes uncontrollably rolling back, tongue and jaw spazzing out all over the place; the initial rush just fucking melts you and reduces life to one desirable outcome: to get that rush again and again and again. It's just such an unbelievably sweet feeling, it literally feels like a deluge of dopamine, it is exactly like that (I think meth also affects serotonin as well, though). Meth just tricks your brain into squeezing out all of its fun juices in one fell swoop. It feels really good, but you won't want to do anything else but it again. Everything else is subservient to that feeling. Even just typing this out makes me shake a bit and feel panicky because it is actually super hard to control yourself around that stuff to the point where your body will move on its own while you just watch behind your eyes. I can only recommend doing it if you're about to die or something, and even then probably not a good idea because it's just too carnal a feeling it's kind of gross. I'm not a moralizer by any means but going cross-eyed with dumb pleasure just kind of feels wrong and I don't think you'd want your last memories to be tainted by such a reductionistic experience.

I’m not that well known commenter in the KZfaq’s commentary section. However, I’m here to say that, as a person who was dealing with this drug almost 4 years ago, this has been the best theoretical exposition in relation to the sensibility experienced in that substance.

I took meth for 2 years, started at a relatively young age (from age 17 to 19), I'm typically an introvert, having taken meth. I felt more social and alive than ever, in a way I did wish that I could be like that, but at the same time was always content in a sense with being an introvert because I enjoyed how introspective I could be. But with meth, I felt like I could manage being extremely introspective and social, it felt like a perfect balance, a seeming unity of opposites into perfect harmony. But the more I got into it, the more I realized how trivial, transient and illusionary this new sense of "self" that I discovered, it created a rift between who I truly was and who I wanted to be (a projection of a fake sense of self from it). It felt like a tragedy in its own right, because the drug consumed my soul (metaphorically speaking), it made me feel like I needed it exist as the "perfect me" that I strive to be. I came to realize how small it made me and how I became fundamentally weaker to a point where I couldn't persist without a mere substance like it. Excluding even that, I would occasionally go through intense crash downs from it, sometimes not sleeping for 3 days, it caused a significant toll on my heart, I've had few cardiovascular episodes that almost killed me, minor heart attacks and so forth, it made my preexisting anxiety worse, I even lost weight and my family started to notice and wondered what was wrong, one day my mother asked me "what went wrong with me", it's almost as if she could tell I was completely miserable because of this drug, it was then that I decided to wake up and quit (Well that and including the fact that it was taking a heavy toll on my heart). After having quit it, my anxiety grew worse, I started having panic attacks months even after taking it, it felt like flash backs of me almost dying were being replayed when I tried to sleep, which would trigger my anxiety and create another panic attack. A year later, I've decided to quit every drug I've ever taken, I quit the last one which was weed a few weeks ago, unfortunately it is in a way a little late, because now I'm on chronic for hypertension and congestive heart failure. My anxiety is still causing me a few problems in my daily routine, but the beta blockers I happen to take (atenolol) work great against cardiovascular diseases and anxiety simultaneously. The bottom line is, these videos aren't myths, they describe exactly what the drug does albeit from a technical standpoint, if you find it hard to quit this substance, I suggest you seek help immediately before it's too late, before it consumes you. It's almost never too late, but it can be when it comes to amphetamines, best of luck in your journey towards a greater sense of discipline, may god be with you.

I’m so grateful I got off that shit! It totally destroyed my life in 1998. Thankfully I was so young that I bounced out of the devastation quickly but I’ve been suffering with extreme memory loss ever since. I think it might be from an accumulated sleep deficit. My favourite thing to do was never sleep. My heart aches for anyone who decides to try this poison ☠️

As an addiction recovery coach working on chemsex and meth dependency, I find that this video is an amazing and comprehensive walk through on meth and the repercussions of its prolonged use. Thank you for sharing, Dr. Sanil.

I live in a small town. I moved back after 30 years. Methamphetamine has totally changed my town. Homeless people, crime, run down housing and people who look like walking skeletons. It's heartbreaking.

As an addict , a long term and chronic user, I can't help but feel like I have really screwed myself up. I've talked to recovering addicts, specially methamphetamine addicts, ones that have had 5, 10 years of clean time, and they say that it never gets better.

Anyone and everyone needs to have self control no matter what you're doing in life. I will not advocate for meth use for anyone, but I believe the major fault lies in people's ability to forget that they still need to eat, drink, find nutrition, and if you know your brain is working overtime then feed it sugars... If you don't eat, take vitamins... Do not let yourself go. One day you will move past it or overcome it and until then take care of yourself. Do NOT let a thing overcome you. Remember you're eternal and this life is just teaching you how to be who you really are... Most people find out a LOT of things about themselves they don't like or aren't okay with and if they have already went that far then the only choice they have left is to choose life and remove all those things they know they aren't or don't want to be. People like to say, "do the drug, don't let it do you" , but once you've crossed that line and you know it's winning you have to make a choice... Fuck videos and speeches... Find yourself and get the fuck out of there. Iykyk

The music you either composed or selected - it goes so well with the subject matter! There's a real weakness in the highest pitch, much like a symbolic audio version of the weakness of a meth addict. The music is also conducive to focusing on the details. Very interesting video and great voice projection.

Also Wellbutrin is slightly effective for speed addiction, and it helped me for a while. A lot of medications that treat it will interact with it in a bad way, so a person has to be ready for recovery to not be in danger from these medicines.

Another important note is that the neurotoxicity is furthered by the hazardous compounds that go into its manufacture. Many of these can cause neurotoxicity as well.

My Son got himself addicted to this drug. It has had catastrophic effects with him suffering from severe psychosis. His whole memory from his childhood changed and he believed things that weren't true. This led to a breakdown of our relationship and i had no choice but to throw him out of my house. He then got progressively worse. His paranoia and psychosis became worse and he broke into my house armed with a knife. He's lost a good job and a family that loved him. He's currently on remand in prison 😢

I stopped talking Venvanse because I was feeling exhausted, confused and irritated. At the university my cognition was really poor. Days after I stopped taking my understanding and comprehension about the subjects that I was studying has improved significantly. Great explanation.

Best existing video on the topic. Thanks.

Great video! I'm going to save it to my "Watch When Clean & Sober" playlist that I created 7 years ago. It currently has 370 unwatched videos.

When i was using, If i got excited about something, i would stutter and the corner of my mouth would twitch making it hard to talk. By the time i relaxed enough to speak clearly i had forgotten what i was going to say lol. I got help after 3 years thank god.

Stuff really stains your brain. Tried it once and still think about the experience to this day. Its not bad but, I find it fascinating that I still think about it to this day. Im really glad i was taken out of that situation otherwise, i would have ended up addicted

Thank-you for the insight, its made me reconsider my meth addiction. I'm now stressed about the effects meth has on my brain, so stressed i might have a burn to deal with the stress...

I like the way your channel is going, looks a lot more fluid, you look more confident and the imagery is much improved. Really would like to hear more on narcotics and drugs with abusive potential. Also maybe you could do a video walking through how overdose goes down with certain drugs

I also did meth for almost 12 years daily. I have severe schizophrenia but I tried to hide it, I do sometimes believe people are still watching me or coming after me, there's a healing curve, it gets worse before you get better

Great video. Very informative. You have a engaging talking style. If you get a chance a microphone might help, with your viewer count. There is somewhat of a not so pleasant echo . Almost like listening to someone talking in an empty hall. But it might be just me. Wishing you the best of success and looking forward to seeing more of your videos.

I had to get on a d2 and d3 partial agonist, ie a-typical antipsychotics, and my brain really started to heal.

Can you explain why Vyvanse(usually high or dosed twice one day) feels almost exactly like meth but dextroamphetamine(Dexedrine) doesn’t. I think vyvanse would be a good SUD drug for stimulants like methadone is for opioids. Study showed people withdrawing in rehab from methadone tolerated vyvanse really well

I did meth maybe a couple of dozen times before and the highs were exactly as everyone describes, for hours on end. The main reason i think why i didnt become addicted were because of the hellish downers that would begin to kick in about halfway through a session, with no sleep. Eventually my brain would just overload with too much stimuli and i would need to sleep but was wide awake. Such a nightmare the images i would see. Then even after i got the sleep, i would have a two week downer, with exhaustion, poor balance, a constant static noise in my head, and a general feeling that my soul had been snatched from me. But then i would do it again. With booze and coke too even. The last time i did it was a year and a half ago where i had the same terrible downer but it didnt disappear as usual two weeks later. It just got worse and it felt like the world was a distant computer game. The brain fog was horrendous and i had to lay in bed for an hour after i woke up every day just to come to my senses. My balance was bad and i even had to stop drinking and anything else, because one sip would trigger my anxiety and a paranoid, confused state. Now even if i stay up longer than 8 hours it always feels like part of my brain wants to shut down or like im on the brink of epilepsy or narcolepsy, so i have to sleep or i'll lose my mind. I can never think straight because i have constant brain fog and cannot stay focused. Even though i havent touched drink or drugs for a year and a half it keeps getting gradually worse, like i have alzheimers, despite being in my 30s. Im out of solutions except for a final one.

I love the music. Seems a bit too positive for a story about permanent dopamine transduction disruption.

Wish we had a pharmacological approach to help those that suffer from Desoxyn, Crystal MAMP, and Adderall addictions! Similar to methadone and Suboxone with opioid addiction! OFC some ppl don’t need continuous CS issued depends rly! Choreathotic movements, neuropathy, psychosis, and deep depressions are tragic to see as example of long term brain damage

Thank you, very thorough and informative 🙏

I am lying if i say never tried this drug,2x session of using 12 years ago,i mananged to stop thru shock cause i had an car accident and the shock of having an accident made me quit,i never even feel the Withdrawal in the 20 days i am in the hospital cause of SHOCK of my accident.I am contented with tobacco plugs now

Great content as always!!!

Fascinating 🧐

Hi i am a long time user but we only smoke around quarter a gram every week

I am learning new things

My life was destroyed bc of crack, crack is by far the most addictive and euphoric stimulant, and the most expensive, you will never have any leftover and you will never have any money and you will be so weird and everyone can tell. Most people i know that have tried an array of drugs will say "meth doesnt really get you high" they are exaggerating slightly bc you have motivation and youre not too messed up to get things done and the buzz feeling is very weak and i have to agree, i first did meth for a week, i stayed up first night then let myself sleep for a few hours each day after that, it was enough to tale the edge off and it got me off of crack and saved my life and i didnt have any huge cravings after, also importantly i wanted to quit, being a crackhead is not something you miss being, from the first hit of crack you are trying not to do anymore but cant help it I smoked (never snorted it or ate it ever) after that over the next couple years bc its fun to get a lot done around the house or be obsessive with a hobby like a musical instrument or fixing a car, my life is back on track and i would argue significantly more than it was previous to crack years, 3.5g lasts a very long time, 1-2 weeks and its so cheap, it pays for itself and then some if you do more production at a job or side hustle like i did, didnt need to do it everyday like hard drugs, i sleep everynight at least 4-5 hours minimum, very very very rarely let myself stay up an entire two and a half days straight, if you do that you start to get weird, as anyone on or off drugs would, ive cut back/out smoking cigs and weed and booze, i eat well everyday, and i feel theres no hangover when you sleep on it, it in fact has almost an anti hangoger effect like Adderol where you wake up ready to go, however if i dont do it for 2 days i def get some longer sleeps in for the next few days, keeping my mind occupied let me go to bed some days realizing i didnt smoke any or even think about it Some of the stories in these comments make me feel as though people have placeboed their brain into having such intense experiences There could also be something to never ingesting it and only smoking it, but meth feels like "pussy shit" (pardon my french) when it comes to druga, esp when you can smoke todays weed and be so fucking high you cant make it to the car let alone drive But like all drugs, its been shown over and over again that its case by case, especially when youre open minded and dont have the expectations some have, some suck at taking certain drugs and let it become their master, some do them like a champion, some die from them, some go on living from them, some get lazy, others get motivated , some get weird, some find their personalities, some ruin their lives, some use it to succeed, some make the best art and music ever done I quit for a year or so twice, currently sober but kinda feel like getting some just for the fuck of it, so i might This is all one case of use, dont let my story alone affect your decision making, i could be a one out of a hundred, listen to this doctor not me, i dont condone letting drugs into anyones life, youre better off never opening the door and risking anything you have

I watched this drug destroy so many people. Even after they finally got off of it (some trading alcohol as their new self medication) having to stay away from triggers - others being diagnosed with neurologist diseases, i.e., multiple sclerosis and Parkinson’s-some have died from their hearts turning to what I call mush.. 30 something’s with pacemakers and defibrillators implanted and still doing the drug until it killed them.. such a straight from the pit of hell drug. Thank you for this very informative video, I got a lot out of it.

Great, now I'm afraid of my prescription Dextroamphetamine. Is it just as bad?

I enjoy these videos. Glad i found this channel.

Interesting about alpha 1 receptors and their effects on the Prefrontal cortex in the context of CFS and brain fog

Thank you i sent this video to others, from Seattle ❤

The interesting question is allowing for appropriate dosing, is taking meth in a drug like Desoxyn really any worse for brain health than other prescription stimulants like methylphenidate or dexamphetamine?

Great video. Very informative and spot on. I’ve been sober 10 years but the consequences are quite awful and long term.

Thank you Doctor ❤❤

I was on meth 24/7 for 9 years. 2 years clean now. Doing really good but seeing this worries me. What have I done to myself??

One of the drugs I think I have seen change someone almost overnight depending on if they snorted or smoked it, and then the ones that take a hot rail because it "looks cool" no hope at that point for awhile, a very horrible drug, the same can be said for crack cocaine but this stuff is just that much stronger.

Maybe you should study my brain. I have done meth since I was 21. But talk about habits, people have 100 dollar a day habits, 500, 1000 dollar a day habits. My habit has been like maybe 40 dollars every two weeks. It started because I didn’t feel I had enough energy to do my job. My job requires so much. I’m a court reporter. Lots of motor skills involved. I’m 55 now. I have dementia in my family, so I figure I will eventually see that happen. But still hanging in there. But I’ve never let it ruin my life, at least not completely. I don’t miss work. I don’t get sick. I do have hypothyroidism. I would like to quit but feel like I’d never be able to keep up with work if I did. Wouldn’t know where to start at this point.

It fries your dorsalatral prefrontal cortex!

i have been doing meth for close to 30 yrs now,i run my business of small equiptment repair sucessfully, i eat regularly,sleep at least 4 hrs a night o keep things tighty and i dont steal nor associate with those who act like methheads and most dont even suspect that i do it and lots. i am battleting a rare luekemia ,had bone marrow transplant 2018 and outliving more than 95% of th 1 in 1.6 million that have so now what?

I want to add that medical science has figured out the entire chemistry of our brains and a new category of supplements are out called Neutropics that increase recovery from almost any deficiency and regenerate damage to the brain

This was very interesting. If possible could you do a video on how opioids change the brain?

nice info. I think your videos could be improved if you got a new microphone and/or recorded in a space with less reflections.

Cam on... Thank you... Merci beaucoup... Dr. Sanil Rege!

I know a lot of drug addicts. The only ones that never get sober or have horrible lives when theyre sober are all meth addicts. The only people that i see have the lowest chance of making out of addiction

Ive been dorsal for 10 years 😮

wow... having had multiple experiences with this stuff, i really appreciate the details of this clip... thank you for the knowledge.... makes me want to learn more about my brain and why this shit is so powerful....

Do these things fix themselves after time without use or are the damages permanent?

First time I tried it I felt like I was having a body orgasm every ten seconds; tried it a second time and all it did was make my heart race. Not worth it so I never touched it again!!

Thank you so much for this detailed neurology lesson, you did very well at explaining things and making them comprehensible.

This comment is probably counterproductive but could filaments be threaded directly through the pleasure centers of the brain,what sort of neurotransmitter storm be caused?(perhaps the only reaction more powerful than meth?)

Been using everyday for a year. Took a couple week break in that time and I bounced right back to my normal self. I’m Stoping cold Turk for a while in a couple of days. I don’t have any cognitive decline or any of the other bad side effects that I am aware of. I do see eyes in the sky now but I don’t think it’s from the drug because the eyes can be seen by anyone who is shown when I point them out.

I tried it once. It was gross. I did not like the way it made me feel. It would not go away. It hung on for hours. I hated every minute of it!

Hello Dr. I've been using crystal meth for about 3 yrs. It started during the second year of the pandemic. For what I've seen, I would say I'm not the typical user, I don't use it in a sexual manner, I don't skip meals, I take vitamins and supplements such as NAD, NAC, Resveratrol, Magnesium etc. I also don't deprived myself from sleeping. I only use it when I'm home, if a go on a vacation I dont use it at all, and honestly i don't feel the "need" of using. But I really want to stop! Any advice on how to stop it? Thank you 🙏🏻

Is it true that eukadol was a precursor to oxycodone?

How does this differ to crack? It sounds very similar.

If one dose is enough for serious mid long term effects why is pychiatry giving it to children for adhd ?

Like a lotta other folks, I’ve accidentally taken meth thinking it was adderall. I’ve taken it for months, quit cold turkey as soon as I found out (this happened last year, I couldn’t tell it was meth since I was taking seroquel as well. It was part of why I was taking the meth), and experienced hellish withdrawals n PAWs for a while after. I’m just now making it out of the depression months later, and I was irritable and unable to function/socialize for literally months. be fucking careful y’all, remember to test absolutely everything every time- usually I do but the one time I was broke as fuck and couldn’t afford reagents, this shit happens. My life has been altered and my teeth body and mind have been damaged. learn from my mistakes if this is something you gotta learn.

I have smoked for over 35 yrs. Sometimes “functional” but mostly have people fooled of my usage at least in my world. I am 53 yrs old and am begining to feel all the effects u mentioned. Or maybe recognizing them. Is there a way or too late to stop and reverse these effects. I am so ready to quit. But cannot quit completely when I do. I don’t have time to sleep it off and recover bc I am functioning. What do I do or if I could smoke something like meth I always wander if that would help? Please help. I am open to anything. Thanks for the video from what I learned really scared me. I thought it was just my age but I can fully see it’s not. 😢 thank u.

Hey just wanna say as an active addict seeking education on what the f**k is happening in my brain, this is extremely helpful and eases my troubled mind a bit. But, the music in the background adds this like dramatic anxiety that I don't fuck with hahaha

Great vid. Any chance of doing one on Benzos? They seem so harmless and mild, until you have to come off them. 💀 Keep these coming! Great info and visuals, but you should invest in a good mic, if possible, to perfect these vids 👌

Will you make a similar video on alcohol?

As a powerful drug, what about the percentage of healing from its addiction? It's obviously much more than Marijuana or prescription drugs addiction.

Do you know if the brain repairs itself even after longterm use ?

I used drugs since I was 15 to 21 I started shooting meth for 6 months at 20-21 I felt something pop in my head & never been the same I been working out for 3 1/2 years & I feel like I’ll never be the same still,what can I do different?

Is there brain damage if you do some just for 1 day were you inject it a few times in 5 hrs then a big thick injection were there was it was like death was coming but didn't and caused ptsd on that big shot even yrs later....but is there brain damage in this case?.

Is the effects of "Acid" or Lsd going to be analyzed in this same manner? Or hallucinogens at all?

I thank you very much for all the information. Bless.

New subscriber here 🙂Could you make a video about tramadol please? 🙌

When do you think psychiatry will make a major inroad with these dopamine-type addictions? They have done a good job of educating the public, but little headway in solving the problem. Not a criticism. Success takes time and a few missteps.

I been sober iv meth for three years some of the crazyest years of my life !

Meth messed me up bad, I.v. User for years, I have crazy paranoia, trust issues, an anxiety like a mofo now even after 11 months clean.

For those of us who were able to get help and stop using meth after years of using it…. Will our brains heal? Will we ever feel some sense of normalcy again as years go by?

Thankfully, I've never done Meth. I've done everything else, however, that was mainly because of depression. My ex wife and I used to do MDMA and speed together for our marathon sex sessions, and that had it's own pitfalls. We were going to buy meth one time on the dark web, but that didn't work out, and luckily, we didn't find it elsewhere and shortly after that, I found out about the dopamine issue with it and I knew that coupled with my tendency towards depression could've been devastating to me. Now of course, I wouldn't take meth, or anything other than THC. I obviously dodged a bullet there.

As a fully functioning long time user, what test should we have done to find out the damage done to our bodies? I eat super healthy with half my diet consisting of fresh juice daily loaded with everything possible needed but I know the only way is to stop. For those Ive seen comment like myself that does it just to maintain and after 20 years youd never even guess was a daily user, is it serving a purpose and is there anything to take its place?

Have you had to make med/dosage adjustments due to blood-brain barrier destruction in meth using (past &/or present) patients?

I am a current struggling user....i use because it has the opposite effect on me. What i mean by that is before taking it my brain just wont shut up, i talk so fast and studder due to it, low energy levels....but after taking it my brain slows down, my talking slows as well amd the studder isnt as prominent as well as higher energy levels. My addiction doctor tells me she thinks i have ADHD which could and would describe a lot of things wrong with me like depression but no antidepressants work....i speak to a psychiatrist about it in about a month. Im going to be honest with my doc and tell him about my use, i want to stop, its killing me but i would kill myself if i had to deal with the thoughts all the time....any input would be appreciated!

I was really hoping to get some better understanding from this but all I hear is really big words 😒

Now society has to prepare for the deterioration of a whole generation of meth users. Health care and providing specific medical care may not be met. We’re struggling to take care of our elderly today, this is scary to think about it

So what about, Ritalin, Adderall,duromine etc?

Do you by any chance, know Dr. Karl Hart, also can u make one of these about ethanol?

What about the levorotary enatiomer?

Thank you for this. I in formally detox addicts

I tried it for one month last summer,in conbination with 2×concerta 54 mg daily,nothing much happened.Dexamphetamine is not so different,it s like morphine vs heroin pure pharmaceutical

I live in Australia 29 years old, I lived through the Australian Ice Epidemic "2012-2016" Ice(meth) was literally everywhere and became half the price during that time period, I got off my absolute head during those years, Even served a prison sentence due to petty crimes, Came out then I started injecting the drug, Last time I injected i overdosed and haven't injected since, But went back to smoking it, I been off it for a while now but goddamn its hard to get off it mentally.

Let me tell you something,whoever reading this ,dont use meth ,meth had my friends hang himself for no reason,you in your head all day with this drug ,all depression not good at all

Can you break it down to lamen terms.

Watching this video gave me euphoric recall...I'm fucked.

Is it worse than a moderate TBI?

Please help me i want to quit but can’t seem to. Why do i love something i hate so much?