Adam Cohen (Harvard / HHMI): Visualizing Activity in the Brain

  Рет қаралды 22,729

iBiology Science Stories

iBiology Science Stories

Күн бұрын

www.ibiology.org/neuroscience...
Talk Overview: The pattern of electrical signals propagated through neuronal networks determines brain function. Adam Cohen examines the possibility of visualizing these signals inside an intact brain using fluorescent transmembrane proteins that are sensitive to voltage. Cohen discusses the barriers to this approach, something he predicts scientists across disciplines will eventually overcome.
Speaker Biography: Adam Cohen is Professor in the Departments of Chemistry and Physics at Harvard University and Investigator of the Howard Hughes Medical Institute. He develops biological tools and analytical approaches to investigate the behaviors of molecules and cells in vitro and in vivo. His lab merges protein engineering, optics, and physics, among other disciplines, on a variety of projects. For example, they have developed a fluorescent transmembrane protein that detects membrane voltage, which is useful in visualizing electrical activity in cells, such as cultured neurons.

Пікірлер: 27
@Vikramt08
@Vikramt08 3 жыл бұрын
This man is like I know the stuff what I am talking about! This is how lectures should be.
@FDND-pl8wp
@FDND-pl8wp Жыл бұрын
I am over the moon for finding this video! Thank you a million times!
@GeoffryGifari
@GeoffryGifari Жыл бұрын
maybe firing pattern with this technique can be combined with other methods to strengthen interpretation? like combining it with fMRI (that tells us about blood flow, and glucose consumption) to get information about energy supply
@spicesmiles
@spicesmiles Жыл бұрын
Phenomenal. Thank you!
@blockfolio
@blockfolio 4 жыл бұрын
amazing
@GeoffryGifari
@GeoffryGifari Жыл бұрын
on the problem of the brain being opaque, can't we use glowing membrane proteins that emit a different frequency? one that can penetrate the human brain. I imagine it like the protein analog of NMR experiments where photons emitted by magnetically excited nuclei are in the micro/radiowave range, passing through matter just fine and can be detected
@GeoffryGifari
@GeoffryGifari Жыл бұрын
on managing the volume of data, maybe we can infuse the voltage trackers region by region instead of the entire brain at once? it will take far longer to get the whole picture though
@davidobrien7794
@davidobrien7794 3 жыл бұрын
It's the 'nice guy' stuff ey bro, thank you bro, it will help
@bodgertime
@bodgertime 2 жыл бұрын
I like your entoosiasm
@chariseveryday
@chariseveryday Ай бұрын
wow just wow
@LisaMaryification
@LisaMaryification 6 жыл бұрын
0:33 'Here's a picture of your brain on a slide'.
@bodgertime
@bodgertime 4 жыл бұрын
Would we know about fluorescence withou George a Gabriel Stokes ? I wonder
@bodgertime
@bodgertime 2 жыл бұрын
indeed, the emission of blue light".......St. Andrews has a great website
@PreferredCustomer
@PreferredCustomer 6 жыл бұрын
Somehow I can't picture this guy ever walking through South Central, LA.
@veritas2185
@veritas2185 4 жыл бұрын
He doesn’t have to, he’s a Harvard professor! SMH
@leif1075
@leif1075 2 жыл бұрын
@@veritas2185 Why does that mean he doesn't have to? Everyone walks sometimes.
@awesomeme39083
@awesomeme39083 7 жыл бұрын
I Hoped this would be about visualization/ imagination as a skill of humans. This is graphic explanations about brain activity.
@citizenschallengeYT
@citizenschallengeYT 5 жыл бұрын
It sure is! Ain't it wonderful! We need more stuff like this. So what if he looks 'endearing' - he's a good speaker and explains it really well. I'm glad I found this. Fascinating and thank you Adam Cohen. now check out this gem. MRI scans, from NIHOD kzfaq.info/get/bejne/oMWWl9OlrdPUmaM.html
@udayakumar3848
@udayakumar3848 4 жыл бұрын
Excellent Adam. Main problem is interpretation. I think I can give answers to ur doubts to some extent. Bcos i have text manual of humanbrain which is millions of years old. Not joking. I research on this past 25years. Ready to discuss
@SuperMaDBrothers
@SuperMaDBrothers 2 жыл бұрын
Where can I find this text?
@udayakumar3848
@udayakumar3848 2 жыл бұрын
@@SuperMaDBrothers hi Adam, these ancient texts r easily available in india, these books are printed with permission from our state government, copied from the palm leave manuscripts from archaeological findings, there are hundreds of books, but only in our Tamil language. I suggest u to just have it and keep it , u will get answers for ur search. If u interested to get I give the publication contact or u want to know any particular topic , I can translate to u , happy to help 🙏🙏🙏
@TheCD45
@TheCD45 4 жыл бұрын
Did he just avoid the use of the term "optogenetics"?????? and instead said light-sensitive light-gated ion channel?????
@mirmasoom
@mirmasoom 4 жыл бұрын
I think OpenProblem1 has been solved ....CLARITY technique #clarity_diesseroth
@ashleynatchaponi435
@ashleynatchaponi435 Жыл бұрын
Cute real cute ♣️❤
@melkenhoning158
@melkenhoning158 3 жыл бұрын
wtf is going on in this comment section
@saltin9525
@saltin9525 5 жыл бұрын
1st disliker!
Matthew Meselson (Harvard): The Semi-Conservative Replication of DNA
13:09
iBiology Science Stories
Рет қаралды 29 М.
Increíble final 😱
00:37
Juan De Dios Pantoja 2
Рет қаралды 105 МЛН
Must-have gadget for every toilet! 🤩 #gadget
00:27
GiGaZoom
Рет қаралды 11 МЛН
Smart Sigma Kid #funny #sigma #comedy
00:19
CRAZY GREAPA
Рет қаралды 21 МЛН
Seeing Circuit Mechanisms
5:44
Cell Press
Рет қаралды 1,1 М.
Beautiful 3-D Brain Scans Show Every Synapse | National Geographic
4:40
National Geographic
Рет қаралды 397 М.
Jeff Lichtman (Harvard) Part 2: Neuromuscular Connectomics
38:07
Science Communication Lab
Рет қаралды 19 М.
Neuroanatomy S1 E4: Hypothalamus and Limbic System #neuroanatomy #ubcmedicine
10:13
UBC Medicine - Educational Media
Рет қаралды 854 М.
The Key to Chromosome Immortality - iBiology & Youreka Science
6:40
iBiology Science Stories
Рет қаралды 9 М.
Torsten Wiesel (Rockefeller University): Exploring the Visual Brain
24:05
iBiology Science Stories
Рет қаралды 25 М.
Jeff Lichtman (Harvard) Part 1: Connectomics: seeking neural circuit motifs
46:32
Science Communication Lab
Рет қаралды 50 М.
All-optical interrogation of neural circuits, Prof. Michael Häusser
17:11
Ingestible origami robot
2:12
Massachusetts Institute of Technology (MIT)
Рет қаралды 879 М.
После ввода кода - протирайте панель
0:18
iPhone 12 socket cleaning #fixit
0:30
Tamar DB (mt)
Рет қаралды 50 МЛН
Нашел еще 70+ нововведений в iOS 18!
11:04
Cadiz smart lock official account unlocks the aesthetics of returning home
0:30
iOS 18 vs Samsung, Xiaomi,Tecno, Android
0:54
AndroHack
Рет қаралды 82 М.