I was head of hematology in a hospital lab in the 80 and 90s. I diagnosed my dad with CLL in 95'. He was in his 60s and died of pneumonia in 2006. Hematology has advanced since I worked it. We went from a Coulter S with oscilloscope cell counters, manual differentials and manual platelet counts, to lasers with scatter patterns. When I worked up my father his lymphocyte count was 70% of the manual differential, with 17,000 total white count, and platelet count of about 120. Smudge cells everywhere. It was an easy slide to read. A very depressing day. How do you tell your father something like that?

I am very much impressive 😊

Amazing Sir

Sir...the mature looking lymphocytes look like the mature lymphocytes only...how would we differentiate them if they're normal or it's CLL

Sir do you have notes of special pathology for medical students?