Alpha-Synuclein - What's it all about?

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Alpha-Synuclein - What's it all about?

Рет қаралды 25,102

Oxford Parkinson's Disease Centre

Күн бұрын

Пікірлер: 12

@gproteintube 2 жыл бұрын

Elegant and scientifically accurate presentation is still relevant to today's forefront of Parkinson's research.

@brandonhealy7158 10 ай бұрын

It’s so amazing that people are finally talking about what alpha-synuclein really does 😊 thank you

@CleanMachineOnline 14 күн бұрын

Very well-done presentation. Animal proteins are the only source of alpha-synuclein (A-SYN) in the human diet. Plant foods do not contain A-SYN as it is only made by vertebrate animals such as cows, pigs, sheep, fish, and poultry and it is also found in eggs and dairy. Most of the misfolding of the A-SYN proteins happens in the gut during digestion, though the proteins may also be damaged (misfolded) during the processing and heat (cooking) of animal-sourced foods. 2017 Study: Vertebrate food products as a potential source of prion-like α-synuclein I am not sure why there is not more focus and education on the dietary source of alpha-synuclein, other than telling people the actual dietary cause of PD is simply not as profitable as the treatment (and drugs) after the disease has already developed. Not only are animal proteins the only source of A-SYN, dietary polyphenols, which are made by plants, (and algae and fungi) not animals, have been shown to inhibit the detrimental effects of A-SYN: 2024 Study: Gut-Brain Axis in Focus: Polyphenols, Microbiota, and Their Influence on α-Synuclein in Parkinson’s Disease

@ivanodriscoll5874 2 жыл бұрын

Good and informative presentation.

@GabrielReis-mf6pd Жыл бұрын

What a great lecture.

@ashtongrist 6 жыл бұрын

why can't we just use bioremediation for scfa to find the enzymes and use whatever that tool is to find the genes and target that gene to the cells of the gut

@robertbernard651 10 ай бұрын

So what is the proper treatment to correct gut book?? What types of probiotics do you recommend?

@stevefoley9448 3 жыл бұрын

Rock and Roll!

@ashtongrist 6 жыл бұрын

where can i buy short chain fatty acid?

@rhyothemisprinceps1617 6 жыл бұрын

Short chain fatty acids involved in gut health are butyric acid (butyrate) and proprionic acid (proprionate). You can buy sodium butyrate as a supplement (in the US); I don't know if there is any evidence of benefits from sodium butyrate supplements in humans. The best way to have more short chain fatty acids in your gut is to eat a diet that is rich in fiber - particularly resistant starch - and have your gut bacteria make them for you. Here's a video on resistant starch from CISRO, Australia's national scientific research agency: kzfaq.info/get/bejne/hK9jfteDmLLToYE.html