ANION GAP | Ridiculously simple

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Күн бұрын

A follow up video to my arterial blood gas video. It was honestly a really confusing topic for me in med school. I've made it as simple as possible with easy to understand illustrations and examples!
PS: For an HD illustrative experience watch in 1080p!
Link to my ABG video: • ABG interpretation | E...
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Пікірлер: 122

@AndreaJoseph 3 жыл бұрын

Note : A LOW ANION GAP is very rare. If an electrolyte test shows a low anion gap, a doctor will usually order a second test, as the results may be due to a laboratory error. Hypoalbuminemia is one of the major causes of low anion gap. Hypoalbuminemia is when a person has too little albumin in their blood. Albumin is an essential protein. Hypoalbuminemia usually occurs because of inflammation in the body. Causes of hypoalbuminemia include: * sepsis * recent surgery * Malnutrition * severe burns * liver or kidney disease Hypoalbuminemia is also considered a contributing factor to having a low anion gap in people with multiple myeloma.

@ryngkatdohtdong1408 2 жыл бұрын

❤️❤️❤️❤️... Tq for the beautiful video

@MeBeCarina Жыл бұрын

it's almost 2am and I had been having a small mental breakdown over this topic for my final in pathophysiology the day after tomorrow ... this video literally SAVED me rn! I acutally, finally understood what this was all about! Thank you

@the0master200 3 жыл бұрын

oh my god! I am a surgical resident in the third year and I never understood this topic, ever. from med school till this day. today I finally understood it. thanks.

@paulbieber7103 Жыл бұрын

Excellent video. Simple, straightforward and informative. Thank you.

@rufaiadamu957 Жыл бұрын

It's explicitly clear and simplified. Thanks a lot.

@kridswonderhowell4541 Жыл бұрын

Bravo! Excellent content! Easy to understand & brief enough to hit the major concept! CINCH BY THE INCH-HARD BY THE YARD

@brunobittencourt9761 Жыл бұрын

Wonderful video, i was lost in this subject. Thank You for the light.

@ernestenyan8676 2 жыл бұрын

This is awesome….thanks for making it easy to understand

@caioplays5542 Жыл бұрын

I love you, you help me a lot in my biochemistry test! Thank you so much

@LouisMCollins Жыл бұрын

This helped me understand Anion Gap. Thank you so much! 🙏🏾

@basimjoseph295 3 жыл бұрын

This was great... Had problem understanding this for long time...appreciate it

@razvanungureanu6305 3 жыл бұрын

Congrats! Very simple and useful! 👌

@samm9993 3 жыл бұрын

You described the concept so well. Shukria

@NavneetKumar-fs9nz 3 жыл бұрын

Thankyou very much.You have explained it very well.

@elsiehyunjoonam9991 3 жыл бұрын

Loved this video! Thank you!

@mahaqalbani4867 3 жыл бұрын

Thank u so much. Plz add more videos particularly abt electrolyte imbalances

@kashmalahadi7198 2 жыл бұрын

Mannnn that was superbbbb!!! Loads of loveeeeee!!!❤❤❤❤❤❤

@naumankhan2872 3 жыл бұрын

You are amazing maim❤️ Keep hard work one day you will cross 1M InshaAllah

@daze8326 11 ай бұрын

Excellent presentation and great information!

@soumitrabhattacharyya6709 3 жыл бұрын

Loved the video..finally understood

@lola-mo5sh 2 жыл бұрын

thank you. concise and very clear..

@AnicaSuki 3 жыл бұрын

you are so talented teaching! you made such a difference on my study! thank you so much and keep creating please !

@AndreaJoseph 3 жыл бұрын

You are too kind , thank you so much.. 😊

@abhineetgupta1827 3 жыл бұрын

Such a underrated channel

@danielcortes3278 8 ай бұрын

excellent video. Constructive criticism, your equation should be written with parenthesis as follows NA - (HCO3 + Cl) = 0 without it , the result is different great video again

@silk.spectre6606 3 жыл бұрын

Wow, I watched it once and learned it. Thank you so much for this video!

@hassamghazi 2 жыл бұрын

The best explanation!

@benh7274 3 жыл бұрын

Thank you, that video helped a lot!!

@amatulnoor7171 3 жыл бұрын

You are a saviour. Pls make more videos

@knraoneurosurgery 4 ай бұрын

this is called giving clear concept

@user-do5hg6vr7e 3 жыл бұрын

Nice explanation mem.Thank you.

@barakatullah1035 Ай бұрын

excellent explanation.

@justinfarmer1933 2 жыл бұрын

Great video! One thing to mention however is the formula should be Na (+K) - Cl - HCO3... or ... Na (+K) - (Cl + HCO3). Basically, you have to Subtract the amount of chloride AND bicarb from the amount of sodium.

@satadruray9787 3 ай бұрын

Really, really excellent. Fantastic

@aSm8full 3 жыл бұрын

finally it make sense now, Thank you

@marklotfy7706 6 ай бұрын

Perfect! Thank you

@ladyvirgo9514 2 жыл бұрын

My lab work says 9.2 is low. I'm a bit confused. How do I raise it?

@divyabharathiak422 3 жыл бұрын

Wow.Really explained very well😊

@nadia7238 3 жыл бұрын

Thank you for the information. I do not find much info if the anion gap is very low, lower than normal range.

@AndreaJoseph 3 жыл бұрын

I’ve just written briefly about low anion gap .. it’s pinned in the comments section of this video ..

@elahedead6357 Жыл бұрын

Brilliant, I just learned

@ThePhenomenals 3 жыл бұрын

Thank You Very Much

@asherbarkany 10 ай бұрын

Thank you so much!

@dr.leelaram 11 ай бұрын

Really concept is cleared now❤

@vivekbio11 Жыл бұрын

👍 great...thanks for amazing presentation.....

@joelbackman4389 Жыл бұрын

Thank you!

@MA-qe6it 3 жыл бұрын

Isnt it Bicarbonate re absorption from Proximal convoluted tubule impairment? In Type 2 RTA at 5.25 ? Pls correct me if I am wrong

@AndreaJoseph 3 жыл бұрын

Hello, thank you for your question. You’re very right that in type 2 RTA bicarb absorption in PCT is impaired ( also called proximal renal tubular acidosis ), but the video speaks about type 1 RTA - the most common type of RTA. In type 1 it is impaired in DCT .. it’s also called distal renal tubular acidosis .. Hope that helps :)

@ummayhabibabably1137 Жыл бұрын

Thank you very much

@cvsheshadri7376 3 жыл бұрын

Nice explanation with figures👌

@tommansoor5230 Жыл бұрын

i have high anion i have 18 what can i do to mack it 12

@cynthiaoliver4469 3 жыл бұрын

Tnk u soooo much! Great video♥️

@cauefaquimcosta2339 3 жыл бұрын

Tks from Brazil

@phorphorbnsk8424 3 жыл бұрын

Thank you very much🌈👍🏻

@elifsarsoy5175 7 ай бұрын

The last example frankly confused me. How does chlorine increase and bicarbonate decrease when the anion gap is in the normal range? Is there no acidosis in the last sample?

@mdnazmulhoda7039 Жыл бұрын

Thanks a lot.

@alejandroibarra55 3 жыл бұрын

This is gold

@muazzama8687 2 жыл бұрын

Can't thank enough 💙

@cynthiaoliver4469 3 жыл бұрын

Does d plus or minus 4 mean that potassium is added and subtracted from d answer?? That is 12? Since the concerntration of potassium is 4meq/l??

@AndreaJoseph 3 жыл бұрын

It means that the range is either plus 4 or minus 4.. it’s just a range. 12-16..

@iruri4u 3 жыл бұрын

Thank you

@jocelynsalmeron733 2 жыл бұрын

Great video !!!

@VitorExpedito 4 ай бұрын

Perfect.

@tomterific390 Жыл бұрын

I've read that an increased anion gap can also result if unmeasured cations decrease (e.g. hypokalemia, hypocalcemia, hypomagnesemia) or unmeasured anions increase. The former (decreased unmeasured cations) is especially confusing, because how can a calculation only involving MEASURED cations be influenced by changes in cations that are NOT measured??? Makes no sense to me, unless those conditions are obligatorily associated with an increase in the measured cation.

@dr.nazninahmed1361 3 жыл бұрын

Thanku so much for this wonderful video..ur new subscriber❤❤

@divyaatri8651 2 жыл бұрын

Awesome video

@indipedia. 3 жыл бұрын

Explanation 🔥

@andrewsalas1154 3 жыл бұрын

Very informative video! My results just came back and my Anion is 5 which seems a bit low. Should I be concerned? What is the best way to increase it? Thank you

@ThatsWhy- 2 жыл бұрын

Take sodium ....maybe you got multiple myeloma so phlebotomy

@nourdolan3022 Жыл бұрын

Have you found out why you have low level of anion gap?

@andrewsalas1154 Жыл бұрын

@@nourdolan3022 yes it was the steroids they gave me in the hospital for covid. That effected the levels from being accurate in the test

@loregasmic 9 ай бұрын

@andrewsalas1154 How did you find that out? I had a low anion gap and I'm trying to meet with an oncologist to test for multiple myeloma because I also had a back injury recently and that's a symptom so I'm thinking it's that.

@andrewsalas1154 9 ай бұрын

@@loregasmic this was a few years ago and I cant recall what caused it now but I believe it was something that caused my charts to be inaccurate.

@stellajaames9116 2 жыл бұрын

Awesome

@yadagirimbbs1 11 ай бұрын

Thank you🙏 madam❤

@nursingbeats8467 3 жыл бұрын

Mam your content is drop dead gorgeous and neat cute easy understandable Mam I need explanation about base excess put one regarding one video mam

@Die_Empty. 3 жыл бұрын

thanks alot

@wtficantgetausername 2 жыл бұрын

jeez that was ridiculously simple CHEERS

@Monika-mb6jh Жыл бұрын

I’m confused by one thing though.. if the high anion gap acidosis has an electro neutral serum as opposed to an acidic one… how do you know the person is in acidosis? And why would it even be classified as acidosis if the person has a normal serum pH?

@atmshuvo44 6 ай бұрын

Electro neutral doesnt mean an even pH.here only ion gap are discussed not pH.

@ebubejosh2573 2 жыл бұрын

This is the best video explaining this 💋💋💋💋 I just subscribed too

@drawesome9317 2 жыл бұрын

hey whatever slides u use pleasse upload them as a pdf on ur telegram channel

@momeenamaheen.5837 Жыл бұрын

very informative

@dr.leelaram 11 ай бұрын

Very good👍👍

@yashvardhansharma999 2 жыл бұрын

Thanx meam

@srimapradhan9174 3 жыл бұрын

Awesome simplification.thank you

@riteshchaurasia4953 3 жыл бұрын

Nice

@blackbirds4 3 жыл бұрын

what about an Anon Gap of 6 what does that mean?

@AndreaJoseph 3 жыл бұрын

Thank you for your question . That depends on the lab we’re using to test the anion gap .. it could be in the normal range .. it’s explained in the video @ 2:50 Because some labs calculate sodium and potassium whereas some others do not include the potassium value ..

@chhotu5643 Жыл бұрын

Please more videos

@philistinezigurath1368 2 жыл бұрын

if the serum is always electroneutral why is it acidosis? acid is neutral?

@rajeevkaparthi190 Ай бұрын

Bicarbonate buffer system in the body tries to keep the pH with in the normal range but only to some extent. If the accumulation of organic acid continues BBS can not normalize the pH beyond its capacity. Hence, there will be acidosis. Meanwhile, the concentration of bicarbonate falls as it neutralize H+ .But, electrical neutrality is maintained due to accumulation of anion component of organic acids.

@infodiff Жыл бұрын

Nice lecture/..

@arshithgowda8728 2 жыл бұрын

U did well

@harshamaloo2080 3 жыл бұрын

Did you take this from vivek sir’s physiology

@AndreaJoseph 3 жыл бұрын

Oh I’m sorry I’ve never watched his videos! I’ll check them out. I took inspiration from Hippocrates KZfaq page, and the book guyton.

@ojpublicacoes 2 ай бұрын

Excelent

@sadhanasekar864 2 ай бұрын

Wow❤❤❤❤

@cloudwalker7001 2 жыл бұрын

Nice👍🏻

@abhinavajith92 3 жыл бұрын

I have understood what you've explained in the video but what is confusing me is this line from Ganong "This gap, which is something of a misnomer, is the difference between the concentration of cations other than Na+ and the concentration of anions other than Cl- & HCO3- in the plasma." And then it says it consists for the most part of organic acids,protein, Sulphuric and phosphoric acid. So according to that definition shouldn't it be Anion Gap= [Anions-{Cl+HCO3}] - [Cations-{Na+K}] I'm not able to wind my head around this

@abhinavajith92 3 жыл бұрын

Ooh i think i got it Using the graphic at 1:52 So Na+(other) Cations = Cl+HCO3+(other)Anions For electroneutrality And thus (other)Anions-(other)Cations = Na-Cl-HCO3? Am i right? This kind of makes sense to me now

@AndreaJoseph 3 жыл бұрын

Anion gap is indeed a misnomer. Because it’s a concept created by us. The term ‘unmeasured’ is really a misnomer , as many of these anions and cations are actually Or can be measured , however they are not included in the anion gap equation (and are ‘unmeasured’ for this purpose). So in reality , in a healthy body there is no gap. Humans have created the concept for our convenience in diagnosis . Hope this clarifies it for you !

@abhinavajith92 3 жыл бұрын

@@AndreaJoseph yes thank you ma'am

@davidstojanov8055 2 жыл бұрын

the best

@Drstar-rg9wp 3 жыл бұрын

Greeeeeeeeaaat😭😩❤❤❤❤❤❤

@riteshchaurasia4953 3 жыл бұрын

If u could explain more detail in case of vomiting..

@meowismeify 3 жыл бұрын

Why doesn't this video mention a Low Anion Gap?

@AndreaJoseph 3 жыл бұрын

I’ve just posted in the comments about low anion gap ..it is pinned in the comments section ..

@Vinodbukka Жыл бұрын

Explain NAGMA with Urinary Anion gap madam

@rohitgahlawat1231 3 жыл бұрын

Made easy

@mounotashopno5113 2 ай бұрын

Amazing❤️‍🔥❤️‍🔥❤️‍🔥❤️‍🔥❤️‍🔥❤️‍🔥 from Bangladesh 💙🥳😊

@DogHonest 3 жыл бұрын

i love you.

@akankshajaiswal7477 3 жыл бұрын

👍👍👍👍👍👍👍👍👍

@aniketdesai7906 3 жыл бұрын

👌👍😊

@normanlabat5335 2 жыл бұрын

I don't need an explanation. I need treatment. What can I do to elevate my anion gap? The range is 8 to 13. Mine is 7 low. How do I elevate it to 8 or more?