Anticholinergic Drug Toxicity: Toxidrome Effects and Mechanism of Action [Pharmacology Made Easy]

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Anticholinergic Drug Toxicity: Toxidrome Effects and Mechanism of Action [Pharmacology Made Easy]

Рет қаралды 11,805

Күн бұрын

Anticholinergic drug toxicity and pharmacology is made easy using this simple trick to remember the symptoms and effects of anticholinergic toxidrome. Great for nursing, medical, and USMLE!
Most anticholinergic drugs are antimuscarinic (few act on nicotinic cholinergic receptors), and their mechanism of action involves blocking acetylcholine from binding to the cholinergic muscarinic receptors of the parasympathetic nervous system.
Anticholinergic drug toxicity or overdose results in many sympathetic-like symptoms because the parasympathetic nervous system is blocked, leaving an unopposed sympathetic nervous system.
Anticholinergic effects can be remembered using the saying "mad as a hatter, blind as a bat, hot as a hare, dry as a bone, red as a beet".
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Timestamps:
0:00 Introduction
0:39 Anticholinergic Examples
1:19 Anticholinergic Mnemonic
1:43 Sympathetic vs Parasympathetic
3:55 Anticholinergic vs Sympathomimetic Toxicity
6:13 Anticholinergic Toxicity Symptoms
6:42 Anticholinergic Workup
8:39 Anticholinergic Management
10:08 Antidote Treatment
11:03 Table & Chart
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#nursing
#nclex
#usmle
#toxicology
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Пікірлер: 21

@ezmed 2 жыл бұрын

🔸Lecture: www.ezmedlearning.com/anticholinergic 🔸Study Guide: www.ezmedlearning.com/store 🔸Membership: www.ezmedlearning.com/member-area-study-guides 🔸Tutoring: www.ezmedlearning.com/medical-tutoring-services-online

@themanwithinflatableknees8770 Жыл бұрын

That sound? That was the penny dropping. Thankyou. Excellent video

@777MAG 2 жыл бұрын

I couldn't find anyone to explain this to me the way you did. I no longer feel like an idiot lol. Thank you, I think I have a chance now to pass my mental health nursing class. The meds are killing me.

@ezmed 2 жыл бұрын

Glad to hear it was helpful! The content can be challenging, and you are definitely not the only one to feel that way. Good luck with your nursing class!

@EyeWatchU2B 3 жыл бұрын

Not a bad video. Really great graphics. However, it is best to maintain clarity about muscarinic receptors throughout the entire video. Things get really confusing when you broad brush cholinergic receptors in explaining anhidrosis.

@ezmed Жыл бұрын

Sorry if that caused confusion! The point that was being made is that the sweat glands are unique in that although they are part of the sympathetic nervous system, they have cholinergic receptors rather than adrenergic receptors. Should have clarified that they are specifically muscarinic cholinergic receptors. Hope that helps! 😊

@HockeyGuy_in_STL 9 ай бұрын

Urinary retention = "Full as a flask"

@jamesgodfrey-tw8jr 6 ай бұрын

Learning this because I need to find the damage I did by abusing certain anticholinergics….

@12chitchat 8 ай бұрын

Thanks

@myqtran93 2 жыл бұрын

Very helpful, thank you so much! Will definitely check out more of your videos.

@ezmed Жыл бұрын

Appreciate it! Hope you enjoy the other videos on the channel! 👏

@rachelarc8837 3 жыл бұрын

Can you do a video on antibiotic toxicity, especially metronidazole toxicity. There is a whole group of people that have suffered from the toxicity long term. It looks like it blocks thiamine receptors but we are not sure how to get out of the toxicity.

@frankpope5097 Жыл бұрын

This is so good!!!

@ezmed Жыл бұрын

Awesome! 🙌 Glad you liked it!

@frankpope5097 Жыл бұрын

@@ezmed absolutely the Dr speaking/giving the lesson is a gem!! I'm currently going through this unfortunately I started abusing heroin and they're cut 90% diphenhydramine and 9% heroin the red as a beet mad dry with urine retention is pure hell