CAC is a late manifestation of atherosclerosis. We don’t have to wait for CAC > 0 to treat the patient. The most spartan of diets associated with exercise would reduce LDL and Apo B to what level? 10%? 7%? It is impossible not to use drugs to reduce cholesterol and MACE.

Atherosclerosis is not a inexorable condition . Is there a level of ApoB that that if maintained throughout life would not let plaques to build up ? ApoB less than 55 mg/dl for instance .