We are pleased to share the Best of Digestive Diseases Week 2024 Abstract review. 45 abstracts were chosen based on clinical relevance and study methodology covering interventional endoscopy, luminal gastroenterology, pancreatology, IBD and hepatology. The presentations were made by Drs. Ji Young Bang, Christina Covelli, Arvind Murali and Mitali Agarwal and the abstract review session was moderated by Dr. Girish Mishra from Wake Forest University School of Medicine. I hope that you will find this abstract review to be useful and of relevance to your clinical practice.