It's like the Death boss fight in Simon's Quest all over again

He can, but to speed run it is pretty boring. Hard is actually hard and slower. Nigthmare its just non stop suffering even if you have the best route most things would be hard to dodge and a lot skills are behind hard rooms; it is possible but its not going to be a cool speedrun.

@@ciclotorneos2544 nightmare new game plus is ez on miriam becuase of the passive shards the zangetsu mode however is super fustrating to finish on nightmare mode no shards level 1 weak dmg etc

Imagine doing 1 hour runs over and over again and getting spanked right at the end by Nightmare Dominique every single time.

You can change blood's colour in the in-game options somewhere. It also affects Bloodless and Red Umbrella's