Botulism (Clostridium Botulinum) Pathogenesis, Symptoms, Diagnosis, Treatment, Prevention

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Botulism | Clostridium Botulinum | Pathogenesis, Botulinum Toxin Mechanism, Types of Illness (Foodborne, Infant Botulism, etc.), Symptoms, Diagnosis, Treatment, Prevention
NOTE: This lesson was re-uploaded to correct errors found in the previous version of this lesson
Botulism is a neuroparalytic condition caused by the botulinum toxin. In this lesson we discuss what botulism is, what causes it, risk factors for getting it, the pathogenesis and mechanism of action of botulinum toxin, types of botulism illness (foodborne botulism, infant botulism, wound botulism), signs and symptoms, diagnosis, treatment and prevention.
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JJ
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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for EDUCATIONAL PURPOSES ONLY, and information presented here is NOT TO BE USED as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
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JJ

Пікірлер: 134

@drSJV Жыл бұрын

You have always great videos. It's a joy to learn with you sir! Thank you very much!

@dzeinali 2 жыл бұрын

Brilliant overview, thanks

@rumaisahyaqoob2051 3 жыл бұрын

detailed and amazing...Appreciative

@lukeodubhda 3 жыл бұрын

very comprehensive, thank you!

@harshavardhan9631 2 жыл бұрын

Thank you JJ medicine that was a very crisp informative video

@cocoalmu4823 2 жыл бұрын

Very informative video, thank you so much

@yasirquershi3070 3 жыл бұрын

Very good information, thanks

@dalaishajones6274 3 жыл бұрын

This video helped me so much with my botulism presentation! I was trying to figure out how to relay the pathogenesis in a less wordy way for everyone to understand, thanks a lot!

@RLomoterenge 2 жыл бұрын

“A less wordy way”. Lol Imma buy you a thesaurus

@dalaishajones6274 2 жыл бұрын

@@RLomoterenge buy yourself a life while you’re at it babes.

@Simbusiri 2 жыл бұрын

Nice, informative. Please keep on proving these wonderful videos

@alyndenis6655 2 жыл бұрын

Just found out this one!Thank you!

@ryanhoyle5389 2 жыл бұрын

a fantastic video thanks!!

@pnrking 9 ай бұрын

Thanks Doctor ❤

@christinaisele7510 2 жыл бұрын

Thank you Sir!

@thilinaalagiyawanna3680 2 жыл бұрын

Thank you very much

@user-fi5mn8gv4z 3 жыл бұрын

very helpful

@ndukanwankwo8393 3 жыл бұрын

Well done

@mitaladenisa-andra4456 2 жыл бұрын

Thank you sooo much 😄❤

@adfinemrising 4 жыл бұрын

i read that you can get botulism from spoiled garlic, but by your explanation, it has to have "zero oxygen" to activate. very nice sir :)

@rocheman3771 Ай бұрын

So what I’m hearing is to not put spoiled garlic in a vacuum chamber

@xDomglmao 3 жыл бұрын

As always, awesome are you working in ID?

@markc2152 Жыл бұрын

Awesome video I cane because I ferment and can and it’s always tricky making sure not to get it wrong because of this and other nasty microbe’s

@hecate3988 2 ай бұрын

Thank u so much u help us a lot💜❤️💚💜

@Idiotasentimentale 3 жыл бұрын

Super nice video

@d-rj509 Жыл бұрын

Excellent video! we know you meant inactivated 120 degrees fahrenheit

@taniocebula Жыл бұрын

Dziękuję

@TheOgi22 3 жыл бұрын

Thanx

@fionmor4893 2 жыл бұрын

so a jar of lets say freeze dried food stored in an air tight container can have botulism in it?

@loganmcgee7947 Жыл бұрын

What are your references? I have to make a presentation for a class and the eight or so sources I have used do not mention about 30-40% of this video. I really need your help please!

@jessea9744 2 ай бұрын

I just pulled a rice cooker out of storage. There is no food in it but there apears to be a film of strch in the pot. Would a deep cleaning be safe or should I throw it away?

@12aiswaryak39 3 жыл бұрын

too good

@bigcountry6988 3 жыл бұрын

I just recovered 95% from botulism.

@ghostedwarrior1968 3 жыл бұрын

How did you get it ?

@bigcountry6988 3 жыл бұрын

@@ghostedwarrior1968 don't know and the food inspectors came to my house and took a lot of my food. It's still a mystery.

@fm9187 2 жыл бұрын

How long did it take to recover?

@lisad724 2 жыл бұрын

Were the symptoms just once off or constamt until you had to seek medical asistance?

@goosee7776 Жыл бұрын

Did you get well,,,how do you test for this...

@HaloWolf102 Жыл бұрын

17:53 With my Safe Serve qualification for being a manager at a fast food restraunt. I was told that spores cannot be destroyed with high exposure to heat. What makes these spores different from the rest?

@brandonmoore284 10 ай бұрын

Never trust fast food restaurant qualifications on spores and bacteria. Cause majority of spores can be destroyed by heat just depends on said heat. I had to correct my managers multiple times on how bacteria and other things work cause they get taught wrong Also do your own research onto things. Everything is evolving in the bacteria, spores and other things so really depends what strain and stuff

@Eshelion 10 ай бұрын

Why is there no fever response to clostridium botulinum from immune system (in foodborne cases)?

@mica8230 Жыл бұрын

I was thinking of doing sauerkraut at home, would you say it’s very risky? I was concerned a the botulism 😅

@bungei91 6 ай бұрын

I know that this might be a dumb question. But is there any way the immune system can fight off this kind of infection?

@shlomitbahtmoshe7786 Жыл бұрын

Hello. I’m on a search to find help for botulinum toxin from dysport poisoning. I got injections for cosmetic reasons and I am now struggling with central nervous system issues a host of others. Has anyone done research on how to remove the toxin after Botox injections have spread in the body accidentally from this? Pl and thank you. I’m in a group that has 25,000 ppl suffering from the toxin due to Botox..😢

@user-bi7hl4lm4h Жыл бұрын

perfect

@abcdef2069 7 ай бұрын

at 18:50, 120 celsius is higher than boiling temp. it is impossible to neutralize them then. will you die just by opening an bot infected bulged can? because it will slightly pop and spread the death spores around you? how can you neutralize the bulged can?

@annaswanson5903 4 жыл бұрын

I got Botox for migraines for the first time recently and didn't have any negative side affects so I loved it so much and it was super helpful so I made a video too just in case you or anyone else watching is interested in seeing it

@LootableCorpse 2 жыл бұрын

That's great but I was really hoping to learn more about where this bacteria comes from and how we can prevent the disease. Is heating food to 120c the only way to kill this bacteria? Are some people immune to invasion of this bacteria or is there a certain amount of this bacteria that our immune system can naturally take care of? Is this bacteria present in honey and corn syrup or do they indirectly affect the growth of this bacteria in the gut? Why is there no risk with sugar or molasses?

@Oceanfreak6 2 жыл бұрын

To my knowledge it won’t be destroyed by heat.

@mermer58 Жыл бұрын

The spores are hard to kill, but the toxin can be destroyed, mainly by boiling food for specific amount of time. The spores are in the soil. (Everywhere really) So all root and higher pH vegetables are suspect and should be home canned in a pressure canner at 240-250° for a specific amount of time. Garlic is known to harbor the spores. So garlic boiled in oil should be refrigerated and discarded after 2 weeks. Boiling doesnt kill the spores.

@mermer58 Жыл бұрын

Honey may contain spores. Spores usually pass through humans without any problem but not infants. Their gut may not be developed enough. Adults with a compromised gut microbiome could allow the spores to go into the vegetative state, but its extremely rare.

@headlesshorseman2644 Жыл бұрын

1:50 - So does that mean that botulism is very unlikely at home trough smelling at spoiled canned food?

@MakramHrebat 2 ай бұрын

How can I get a PowerPoint presentation?

@legionnaire2017 2 жыл бұрын

Can this toxicity infect to surrounding people through spraying😥?

@YugoGTI95 2 ай бұрын

i ate a banana that was black outside and on top of the inside but i ate the parts where there wasnt any black or brown and it tasted good and normal and smelled normal. am i at risk plus the banana was in the fridge for two days.

@lourdesmiranda8093 2 жыл бұрын

How can i get anti dote i was injected anti tetanus toxid now im suffering my body due to the injection

@miledsaliba5485 2 ай бұрын

article links?

@captcooper5159 Жыл бұрын

There is a minor mistake in your talk. In the slide about prevention you say you need 120°C to inactivate the Botulinum Toxin. That is incorrect. the Temperature needed to inactive the TOXIN in 80°C. Cooking something at 100°C for 5 minutes and allowing all components to reach a core temperature of 80°C reliably deactivated the TOXIN. 120°C cooking can only be achieved in a pressure cooker and this kills the SPORES. Otherwise, good presentation. A- 🙂

@yoman7777 Жыл бұрын

Mistake 17:30 , I think it’s botulinum antitoxin not toxoid , toxoid is vaccination but passive immunisation is antitoxin

@ngbdq 2 жыл бұрын

This poisoning does not happen very often, thus it is often misdiagnosed for something else. People die of breathing difficulty. Anatoxin is not readily available in hospital. When they get the anatoxin, it is often too late.

@mermer58 Жыл бұрын

True! I cringe seeing all the Rebel Canners on TikTok using unsafe methods and canning foods that are expressly ones that you should never can at home.

@medini2 Жыл бұрын

Yes....I was wondering why he said the mortality rate was only 5-10% at the beginning of the video. I would think the mortality rate would be much higher. Unless some of the strains are not as toxic and/or they took antibiotics and later discovered by lab that they had clostridia. The key then would seem to be early antibiotic treatment and then detox from the toxins.

@karna6634 Жыл бұрын

@@medini2 cuz mortality only happens on cardiac arrest or any similarly sever to that . normally they got treated but have irreversible effect !

@HappytreeLuis Жыл бұрын

@@mermer58 Check out the "high meat" community...

@Ranjitkumar-ll6lw 4 жыл бұрын

Kousa medicine lena chahiye

@sonnydash4987 9 ай бұрын

For the past couple year's I've seen teens walking around with their eyes half opened looking "stoned," but i now think they are mimicking something much worse.

@mandyaaronduvawkin2067 2 жыл бұрын

I'm confused. So bulging canned food means air may be present and that means C. Bot may be present but i thought it was a reduced oxygen toxin.

@fionmor4893 2 жыл бұрын

maybe it is Botulism can grow in a Co2 environment but not an O2 environment.... since the gas expelled from sugar consumption by either yeast or Botulism is not Oxygen it is CO2

@drSJV Жыл бұрын

Its gas from the metabolic action of the toxin

@fionmor4893 Жыл бұрын

I was told the gas in the bulging can or jars (why you never keep the rings on your home canned goods)... is from a secondary contaminate of yeast.... which consumes any sugar and produces C02.... that was why Botulism can live in the bulging jars and cans..... home canned goods will pop their lids when there are contaminates like a yeast

@mermer58 Жыл бұрын

Bulging canned food means spoilage. Period. There are other bacteria at work in that case, but if conditions were favorable, botulinum toxin may also be present. Under no circumstances will boiling kill all the bacteria that may be present, so dont eat it.

@user-ib6cf8kg4l Жыл бұрын

It’s not “air” it’s gas as a by product of decomposition and by product of bacteria etc etc

@aarondavis5535 Жыл бұрын

I had this a long time ago I had a fever of 105 well spoiled turkey I was told it was good I thank I was puking and the runs at the same time 3 days later I went to the hospital could barely walk dad had to help me UC davis medical center they told me what I had

@jana.a3342 Ай бұрын

Are you Canadian?

@trevr9924 Ай бұрын

Watched just to hear someone pronounce botulinum. Stayed for the rest

@meowzerse.a.7611 2 жыл бұрын

15:36 that photo just appears- Was there a specific purpose for that? 👀

@blueprincesses6403 3 жыл бұрын

I ate vegan pate that contains clostridium botulinum (I didn’t know until the government send out emergency warnings) I’ll see the doctor tomorrow. I feel terrified.

@ella-rn9td 3 жыл бұрын

oh wow. are you okay?

@blueprincesses6403 3 жыл бұрын

@@ella-rn9td I’m ok now. The doctor said no problem. I’m still alive now. Thank you Ella. 🥰😂

@ShiratoriIsOffline 3 жыл бұрын

@@blueprincesses6403 glad you're okay

@ShiratoriIsOffline 3 жыл бұрын

@@blueprincesses6403 did anyone got botulism though?

@blueprincesses6403 3 жыл бұрын

@@ShiratoriIsOffline Thank you! Somebody died in my country because of it. The antidote takes so long to be shipped to my country.

@edj9202 2 жыл бұрын

Alert and responsive that shits scary

@alixxgamer5261 4 жыл бұрын

0:40 does that mean that a clostridium botulinum infected person can be cured by hyperbaric oxygen therapy?!

@jjmedicine 4 жыл бұрын

A hyperbaric environment would effectively kill the bacteria (since it is an obligate anaerobe), but most times, Botulism is due to ingestion of a toxin, not the bacteria itself, so hyperbaric oxygen therapy would not be effective in treating it. Hope that helps :)

@alixxgamer5261 4 жыл бұрын

JJ Medicine yeah I got it ... thank you 🙏🏻

@Ranjitkumar-ll6lw 4 жыл бұрын

Sir ji skin me becterial infection hai

@destfuehler9724 Ай бұрын

those damn honey garlic videos

@arasoran253 2 жыл бұрын

I don’t get it, do the toxins produced by the bacteria itself or its spores?

@mermer58 Жыл бұрын

The toxin is produced by the spores when conditions are favorable.

@arasoran253 Жыл бұрын

@@mermer58 thank you so much I got it now🙏

@nihilisticprophet6985 Жыл бұрын

How to prevent Botulism from Botox? Seems like it’s a lot more common than we thought

@happyChappy96621 Жыл бұрын

Easy…don’t get Botox. That’s how to prevent it.

@blueprincesses6403 3 жыл бұрын

Could anyone please tell me if this botulism can be cured completely without leaving after-effect? I’m worried about my life

@yosiyohanes9719 3 жыл бұрын

Ofc, it can be cured. Use hyperbaric oxygen to kill the etiology (C.botulinum) and remove the toxin using C.botulinum toxoid (was listed into this video).

@blueprincesses6403 3 жыл бұрын

@@yosiyohanes9719 thank you very much!!!

@spooonpro614 Жыл бұрын

@@blueprincesses6403 how are you doing now

@blueprincesses6403 Жыл бұрын

@@spooonpro614 I'm totally good! Maybe the vegan pate cans I ate luckily didn't contain Botulism! I'm still alive!

@spooonpro614 Жыл бұрын

@@blueprincesses6403 bruhh I thought you were diagnosed, either way good for you

@blueprincesses6403 3 жыл бұрын

I ate vegan pate that contains clostridium botulinum (I didn’t know until the government give citizens emergency warning yesterday) I’ll see the doctor tomorrow. I’m scared 😟.

@James-uw9ku 3 жыл бұрын

How did it go? I’m in similar circumstances

@blueprincesses6403 3 жыл бұрын

@@James-uw9ku I’m alive. Some people become very sick and must be hospitalized. I don’t get sick so the government tell me it’s okay, no problem.

@bdee1084 5 ай бұрын

Began what?

@dickheadrecs 8 ай бұрын

some people love it, get it on purpose

@tinaparker5248 2 жыл бұрын

🧐👍🤝

@Sharkenite 6 ай бұрын

Well guess I'm throwing away my fermented Garlic and Honey...

@Soviless99 2 жыл бұрын

im trying to figure how to infect myself with botulism. i heard someone once say “what ever doesnt kill you, makes you stronger”. so i intend on becoming superhuman by getting every bacteria and ailment known to man.thank you so much , very informative!

@fm9187 Жыл бұрын

Dont do it man im suffering now from a medical injection of botox. Not nice

@kellymccoy8645 Жыл бұрын

@@fm9187 what was your symptoms on your body? Did you start getting sensations on your body like pins needle all over your body and itching

@jellypie6829 Жыл бұрын

Cant tell if this is satire or not 💀

@fm9187 Жыл бұрын

@@kellymccoy8645 i had a whole range of symptoms dizzy headaches sensitive skin depersonilsation body palpitations feeling paralysed when walking state of confusion just extremely strange

@bdee1084 5 ай бұрын

@@fm9187stomach issues?