8 years!!! How r u? ur career ?

Same hereeee

Thanks for the information 😀

No

yeah I would say its about local invasion not metastasis

Agreed

More power to you and your wife buddy. I hope everything turns out to be well.

Thankyou Gaurav for your reply much appreciated. Ann is going for a CT scan in 2 weeks time to probrably determine the appropiate procedure to continue with the treatment she requires. Will keep you informed. Once again your videos are brilliant and I shall. if any of my friends/relatives have any upsets like we are having, I shall direct them to this video. T@@_gauravdeep_

@@georgebelfield7802 Hoping for the best. Take care.

@@_gauravdeep_ Ann had first chemo last week, she felt a little bit poorly but she had to inject herself with certain drugs etc. Which I think made her worse but never the less it will make her better. At the end of the day I would like to say if it was not for your video on you tube I would not have had a clue to whats happening to my wife.

Kaha hua

it is called tumor induced angiogenesis, so basically tumor cells also secretes growth factor to help the cells grow and some of the growth factors are also a growth factor that could induce the making of new blood vessels (angiogenesis) such as VEGF . Because we know that cells need protein (which contains within the blood) thus it causes angiogenesis so that the tumor cells could grow more. i hope this helps🙏🏽

Hello...Stage 4 cancer is treatable..BUT it is not curable. Someone who has Stage 4 will be receiving treatment for the rest of their lives. The prognosis (how long someone w/stage 4 will live) depends upon different things, one of which is 'where' the cancer traveled to, ( lung, liver, bone, brain) and/or 'how many tumors' there are, etc. A secondary, metastatic tumor might be able to be removed, but that will not cure the cancer. Once you have it, (stage 4--metastatic cancer) you will never be "cancer-free." Metastatic cancer is terminal....it will eventually cause death. I have metastatic breast cancer, (stage 4) in my bones. So my diagnosis is now called "Bone Metastasis," or "Bone Mets" for short. In July of 2021 my prognosis was 3 & 1/2 years at the most. But keep in mind, that is only the Dr.s educated guess...it's just an "estimated" amount of time.

Usually cancer cant spred to muscular organs such as heart bcoz its lined by endothelial cells

Ur presentation is impressive

Breaking

They do but it is very rare - form 0.25 percent of all cancers. Primary cancers in the heart are called angiosarcomas. It's very poorly understood but it's hypothesized that the heart cells, myocytes, have a very tight proliferative cycle thus making it difficult for cancer to survive and thus metastasize. Therefore, most cancers of the heart would be benign anyway and found in autopsies from patient's dying from other diseases.

Thank you for your information

Also because it depends on the microenvironment of the sites. It is called the Seed and Soil hypothesis, If the primary site has a different microenvironment (Growth factors, nutrients, cytokines etc..) than the secondary site, it is hard for the tumour cell to metastasis there as it won't live. Lungs are perfect for breast-originated cancer cells due to to similar microenvironment, but maybe breast and heart have different microenvironment which makes it hard for a metastasised tumour to survive in?

+Yashika Raghuwanshi well I know the blood vessels that grow toward cancer from angiogenesis are considered 'leaky' - the gap junctions aren't as tight between the endothelial cells forming new veins. The microenvironment of the tumor allows for some cancerous cells to break off from the tumor and enter those veins. I suppose the case may be similar in lymph vessels, but I'm not sure - i guess we can look it up in PubMed or something

Perhaps. There wasn't any mention about the formation of new lymph vessels as well. But your assumption might be true. I looked it up but didn't get a clear answer.