husbands new birthday 12/12/19 cart-t at UCLA west la CT/Pet 2 times NO CANCER find. Dr Larson & great stuff she created new life for my husband, THANK YOU !!

i am an oncology nurse, it is amazing scientific treatment. 10 years back, i never thought about this kind of Tx, now i can image all kind of cancer can be treated without suffering for the future.

Very clear and informational talk!

Thank you for all Sarah Larson.

Excellent presentation! Thank you so much for all of your hard work!!!

My dad battled stage 4 lymphoma for a year with aggressive chemos, 2 days prior to do his CAR T cell therapy he caught Covid, which he battled for months to get approval in the end he couldn’t undergo the therapy with Covid, in 2 weeks when he almost beat Covid, the tumor in his brain was too far advanced RIP 2/24/22 😔 He was so close, all because my coworker was forced to work with Covid which gave it to me, he knew my situation and to give a me heads up about positives, my boss didn’t give a dam and didn’t tell me til 2 days later 😔

Amazing, I haven’t watched anything so interested and at the same time understanding very little of it, since it is at such a high medical language. Go on with this amazing work there are people who really need this! You are heroes.

Excellent Presntation ! thank you from Egypt

Thank you for the info. Very well done.

How exciting! Great work, thank you so much for sharing with us

Thank you for a clear and concise presentation

Excellent lecture

Outstanding......👍

awsome presentation!

can you explain how it response toCD13&CD 10

Great video. Quick question. Why can’t we get better simulating treatment and measure the possibility of resistance of the patients cancer in vitro. That way you could know ahead of time what patients would get resistant and which would respond.

Well done. Very informative

You're all unsung heros! Dr. Larson, this presentation is amazing! Thank you!

Does this work for bilineage leukemia aka mixed phenotype leukemia?

great explanation 👌🏻🤩

Are any facilities doing this in Oklahoma.

Kind of confused, at 4:45 you show an Ig (clearly with the forked Hc and Lc) but unlike most B-cell membrane bound IgM's this one has a CD28 and CD3-zeta chain domain (features commonly found in T-cells (not B-cells)). Why is that?

There are several tips for treating incontinence at home Try Kegel exercises- which involve flexing the same muscles you use to stop the urinary flow. Consider using losing weight if you are overweight excess belly fat puts pressure on the bladder and the pelvic muscles. Shedding a few pounds if you are overweight can help restore your bladder control. See if you can train your bladder - put off going to bathroom. Try to delay urinating by 10 minutes and build up to 20 minutes etc. Try magnesium and vitamin D Use Quiting smoking. Nicotine can irritate the bladder. (I read these and why they work on Nilah control plan site )

а есть ссылка чтоб с переводом посмотреть?

Is this recommended for HPV 16 & 18 Head & Neck cancer, which is not a blood type cancer like leukemia and lymphoma

very nice

Using a retrovirus as a vector is genius.

I'm starting CAR-T for CLL 11/20/19

Im suffer suffering from this Horrible Disease, and CAR T CELL THERAPY AND IMMUNE THERAPY are amazing options. I live in NORTHERN CALIFORNIA (SACRAMENTO). Besides UCLA, are there any other Trial, Hospital, or Clinic that will do it treatment. I need this treatment ASAP!. Thxs.

Its biriefullll

Can you get this therapy even if your cancer has spread to the bone marrow

Can it cures completely carcinomas

Have any clinical trials been conducted with CAR-T cells targeting solid tumours such as Osteosarcoma? My son was diagnosed with Osteosarcoma in June 2018, and since then he has had limb salvage surgery & multiple rounds of aggressive pre- and post-surgery chemotherapy. Sadly he has had a few relapses since his treatment finished earlier this year, and his recent PET scan in November 2019 has detected multiple tumours throughout his body, including in his lungs. He is now back on chemotherapy, and we are now resigned to the fact that the chemotherapy is just a short term solution. We have read up on CAR-T cell immunotherapy, which seems to be quite effective, and would be very grateful if you could advise whether this may be an option in treating our son's diagnosis. If not, are you aware of any other treatments available? Thanking you very much in advance.

King 😚💋❤🙌

16:25 future targets and other cells ?

22:18 Suicide gene (Safety off switch)

Does anyone know, how does the car T cells specifically target only cancer cells? How do they avoid killing normal tissue? For example with breast cancer, how does it target cancerous cells while leaving normal breast tissue alone?

numbers are just unprecendented! I know the future of oncology is immunotherapy. Thank you for your job!

Wat about auto transplant

8.01

25

Why is it so hard to fight pAncreatic cancer ?

4:40

10:43

Fit

Regulatory T-cells are natures off-switch.

19:18

Hot doc.

too bad such a hi tech explanation with out clear crisp audio.

So we just gonna act like this isnt the exact same thing that happened in the movie I AM LEGEND?

Dude I love Sarah what’s ur number

6:08 Inactivated HIV (cannot replicate)

CAR-T cells… is this a designer drug?

ok... serious question...... is she single? :D

So this only works if they take the stem cells from a donor. I don't know why anyone would donate their stem cells, lol.

Nope

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