Celiac Disease: How Reliable Is Genetic Testing?

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Dr. Lucia Aronica, PhD

Dr. Lucia Aronica, PhD

Жыл бұрын

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🤔 Curious about the accuracy of direct-to-consumer genetic testing for conditions like celiac disease? In this #HealthyBites clip, Dr. Ahmed El-Sohemy shares a compelling case study, emphasizing the importance of comprehensive genetic and functional testing for precise health insights.
Kew Takeaways:
* 23andMe has played a significant role in democratizing genetic testing and making it more accessible.
* While 23andMe provides interesting and fun genetic information, caution is needed when interpreting health-related data.
* In a case study on celiac disease, 23andMe only tested for 2 SNIPs in the HLA Gene region, while our test examines 6, resulting in a misdiagnosis.
* Antibody and biopsy testing confirmed celiac disease, contradicting 23andMe's report.
* 23andMe looks at random markers and lacks comprehensive insights into certain genetic traits.
* Hair type, being a complex trait, cannot be accurately determined by the limited markers tested by 23andMe.
* 23andMe may provide accurate information for specific markers but its overall coverage is limited.
* Comprehensive genetic testing provides more reliable and comprehensive information for health-related genetic markers.
* It is essential to exercise caution and seek further testing when using 23andMe for health-related genetic information.
* Genetic traits and diseases often involve multiple genetic markers, and relying solely on 23andMe may lead to inaccurate conclusions.
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Recommended playlists:
💪 Stanford Lectures on the biology of longevity with Dr. Lucia Aronica: • The biology of longevi...
🥑 Ketogenic Diets and Intermittent Fasting:
• Ketogenic Diets and In...
🍏 Healthy Bites playlist: • Playlist
🧬 Stanford Lectures on Diet and Gene Expression with Dr. Lucia Aronica • Diet and Gene Expressi...
🇮🇹 Parli Italiano? Nutrizione e genetica con la Dott.ssa Lucia Aronica
• Nutrizione e genetica ...
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Пікірлер: 6
@user-sd1qr5il6k
@user-sd1qr5il6k 7 ай бұрын
You are so right! Most doctors say only HLA DQ2 OR HLA DQ8 are Celiac. I am Celiac and have HLA DQA1:05. What about HLA DQ 3, 6, 7 and HLA DA1:05 and I am Celiac.
@alittlebitoflight
@alittlebitoflight 9 ай бұрын
Do any of the commercial options (My Heritage, for example) cover the same markers for coeliac predisposition as the interviewee's company does?
@jaimerr8826
@jaimerr8826 5 ай бұрын
I have the... HLA- DQ rs4713586 ( AA) / rs2395182 ( TT) / rs7775228 ( TC) and HLA-DQ 2.5 rs2187668 (TC). intergenic rs917997 ( TT) LOC105371664 rs2816316 ( A) and blood test 16 ttg or something. how much of a celiac change do I have, I have an appointment for an endoscopy, but I'm scared asf to eat gluten. I also have depression and anxiety most of my life. Don't know if it's childhood related or celiac/gluten related.
@mariavento7308
@mariavento7308 Жыл бұрын
C'è un modo per avere i sottotitoli in italiano?
@LuciaAronica
@LuciaAronica 11 ай бұрын
Carissima Maria! Hai provato a vedere se è possibile attivare i sottotitoli italiano cliccando sulla rotella in basso a destra il video? Dall’anno prossimo voglio aprire un canale interamente in italiano.rimane sintonizzata!
@il3mendo
@il3mendo 8 ай бұрын
Se hai qualche domanda fai pure
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