I speak for all of us med/premed/nursing etc students when I say you are the best at explaining these concepts!

God bless you, i have listened to my professor recorded lectures for hours and tried to read the book and none of them made sense. But you literally explained them in such a short amount of time and with such good details and with nice delivery! I really appreciate your time and effort! Thank you Dr. Ninja

Sir, I just wonder, how much happy you are during lecture , you are truly passionate about teaching....hats off sir, you are truly amazing, love from India 🇮🇳

I have a test covering this material today. Can't believe you just published the exact video I need to help understand these concepts! Dude, you're a legend! Single handedly getting me through my online Biochem class, no cap. Thank you for providing this for the public!

I see nobody is speaking for the vet students, so I will. This is amazing, I hope I pass my cellular biology exam. Thank you ❤

You saved me! Thank you for this lecture. I’m starting Medical Physiology this September and I needed a reminder of the fundamentals of cell processes and their interactions. Long life to you, Ninja Nerd

Love your videos and I just want to tell you that you guys have been a MAJOR help in me getting through med school these past few years, just have one request that could you please upload more pharmacology lectures? They have been extremely helpful in me getting better grades on my exams!

Me watching this video in 9th grade and still understands everything thing is crazy.Great explanation sir love from India 🇮🇳

You are doing well sir for mbbs students Keep it on for us (students) Love from India 🇮🇳

Why can't our professors teach like this?

zach knows his stuff through and through. natural born teacher, amazing communicator!

You my ninja. Damn good job on the explanation and "practical application" for lack of a better term

Genius 🧠🧠🧠 at work again Much love from Sierra Leone 🇸🇱🇸🇱🇸🇱

As a graduate MSN student just beginning pathophysiology, this has been tremendously helpful. I consider myself a visual person, and the visual aids help me comprehend and remember the process of "fluidity". Keep it up.

THANK YOU SO MUCH. I've got my A level biology exam in a few weeks, so this is going to be INSANELY helpful

Hey zach, cannot thank you enough for your videos, they're literally saving our lives! I know its not the right place, but would you consider going back to neurology and make a video about the medial longitudinal fasciculus? Again, keep up the good work! When i finally finish med school and start working, I'll make sure to send part of my wage someday. YOU'RE THE BEST!

The best thing bout ur videos is pictorial representation of everything

I wish more teacher teach like this for these types of subjects rather then read off thier long worded slides.

Absolutely wonderful teaching and explanations. Thank you for your help!

Superb video as always, thank you to the whole ninja nerd team you guys rule!!!

Thank you for this lecture, you made me understand the whole concept ❤

Thankyou for this lecture,you never fail to deliver the best of the best.

Wether or not I understand what you have been ranting about for 40 minutes I love your videos, keep up the good work!

This was made so well! thank you so much Ninja Nerd! I wont lie I thoguth at the end the video ended and i started to watch a different video but it was embedded into this video lol.

you are the best teacher in the world.

Yiiiiiipiiii ..... Tomorrow is my ppr ... And I can't search any vedio ..finally .. I found 😘

Learning about cell membrane and it's functions was never so easy and addictive 🤩

hi mr im talking to you from algeria and im gonna say that you are a great teacher thank you soooo much

Thank you so much. This Video explained what I’m learning this week, wish me luck!🙏🏼

I’m taking biochemistry and I need to review cell membrane! So this should be helpful I hope! Thank you!

circuit methods, simulations to characterize membrane in detail obtaining permittivity, charge regulation with time, ion-ion, particle-membrane interactions are published in membrane journals includes journal of membrane science, journal of polymer science part B: polymer physics, other journals name required is also must

I’m passing my class because of you !

Very helpful, Special thanks to NinjaNerd

This man is made of brainsssssss 👀

you make nice videos which includes both animation and teaching 😇😇😇😇😇

Great Channel! Zack we please get a Sepsis video please

Wao what a teacher he is

About the transverse diffusion, won’t it mess with the phosphatidylcholine-phosphatidylserine orientation between the inner and outer layers of the lipid membrane? Thanks a lot for providing those much informative lectures for free. I can never be thankful enough and I’d support this channel whenever I am able to :)

You are the best teacher of the world❤

Can any one explain the mechanism how glycocalyx help in water control

You are literally saving my Masters degree ❤❤❤

I mean the best teacher that existed

Thank You

Thee besttttttttt proffersor everrrrr🙏🙏 luv from India❤️

His Passion is unmeasurable

The awaited finally out🔥🔥

this is now my go-to for cramming before a bio test

actual life saver

Membrane Lipids: Phospholipids: Phospholipids form the basic structure of the cell membrane, arranged in a bilayer. The phosphate head is hydrophilic (water-attracting), while the fatty acid tails are hydrophobic (water-repelling). The composition of phospholipids varies between the outer and inner leaflets of the membrane. Cholesterol molecules are embedded within the lipid bilayer, influencing its fluidity and stability. Transport Across the Membrane: Diffusion: Simple diffusion allows small, non-polar molecules to pass through the lipid bilayer. Lateral diffusion refers to the movement of phospholipids within the same membrane layer. Transverse diffusion involves the flip-flopping of phospholipids from one layer to another, facilitated by enzymes like floppase and flippase. Membrane Proteins: Integral Proteins: Integral proteins span the entire lipid bilayer and can act as channels for molecules to pass through. They have strong interactions with the hydrophobic core of the membrane. Peripheral Proteins: Peripheral proteins are found on the surface of the membrane and interact weakly with the lipid bilayer. They are often involved in signaling and cell adhesion processes. Functions: Transport proteins facilitate the movement of molecules across the membrane, either through channels or by actively transporting them. Exocytosis and endocytosis involve the fusion of vesicles with the cell membrane, allowing materials to be released from or taken into the cell. Receptors recognize specific molecules (such as hormones) and initiate cellular responses. Cell adhesion proteins help cells attach to each other and to the extracellular matrix (ECM). Enzymes catalyze chemical reactions at the membrane surface. Gap junctions allow direct communication between neighboring cells. Glycocalyx: Composition: The glycocalyx is a layer of carbohydrate molecules (sugars) attached to proteins and lipids on the cell membrane surface. Functions: It helps regulate cell-cell interactions, including adhesion and recognition by the immune system. The glycocalyx also plays a role in protecting the cell from dehydration and maintaining proper fluid balance. Membrane Lipids: Phospholipids: Phospholipids form the basic structure of the cell membrane, arranged in a bilayer. The phosphate head is hydrophilic (water-attracting), while the fatty acid tails are hydrophobic (water-repelling). The composition of phospholipids varies between the outer and inner leaflets of the membrane. Cholesterol molecules are embedded within the lipid bilayer, influencing its fluidity and stability. Fluidity of the Cell Membrane: Proper membrane fluidity is essential for the functioning of membrane proteins, including receptors, transporters, and enzymes. It allows these proteins to move within the membrane, interact with other molecules, and perform their specific roles. Fluidity also affects cellular processes such as endocytosis, exocytosis, and cell signaling. Transport Across the Membrane: Diffusion: Simple diffusion allows small, non-polar molecules to pass through the lipid bilayer. Lateral diffusion refers to the movement of phospholipids within the same membrane layer. Transverse diffusion involves the flip-flopping of phospholipids from one layer to another, facilitated by enzymes like floppase and flippase. Membrane Proteins: Integral Proteins: Integral proteins span the entire lipid bilayer and can act as channels for molecules to pass through. They have strong interactions with the hydrophobic core of the membrane. Peripheral Proteins: Peripheral proteins are found on the surface of the membrane and interact weakly with the lipid bilayer. They are often involved in signaling and cell adhesion processes. Transport Across the Membrane: Transport proteins facilitate the movement of molecules across the membrane, either through channels or by actively transporting them. Exocytosis and endocytosis involve the fusion of vesicles with the cell membrane, allowing materials to be released from or taken into the cell. Glycocalyx: Composition: The glycocalyx is a layer of carbohydrate molecules (sugars) attached to proteins and lipids on the cell membrane surface. Functions: It helps regulate cell-cell interactions, including adhesion and recognition by the immune system. The glycocalyx also plays a role in protecting the cell from dehydration and maintaining proper fluid balance. Fluidity of the Cell Membrane: The fluidity of the cell membrane refers to its ability to adapt its shape and movements, a property essential for the proper functioning of cells. The fluid nature of the membrane allows for dynamic interactions between its components and facilitates various cellular processes. Factors Influencing Fluidity: Temperature: Temperature plays a critical role in membrane fluidity. At higher temperatures, phospholipid molecules have increased kinetic energy, leading to more rapid movement and greater fluidity. Conversely, lower temperatures result in decreased fluidity as molecular motion slows down. Cholesterol helps maintain membrane fluidity over a range of temperatures by preventing excessive solidification or fluidization. Composition of Lipids: The composition of lipid molecules within the membrane significantly impacts its fluidity. Unsaturated fatty acids contain one or more double bonds, introducing kinks in the fatty acid tails and preventing close packing of lipid molecules. As a result, membranes containing a higher proportion of unsaturated fatty acids tend to be more fluid compared to those rich in saturated fatty acids, which lack double bonds and have straighter tails. Presence of Cholesterol: Cholesterol molecules are interspersed within the lipid bilayer, where they interact with phospholipids and other membrane components. Cholesterol acts as a buffer against extreme changes in membrane fluidity. At moderate temperatures, cholesterol restrains the movement of phospholipids, reducing membrane fluidity. Conversely, at low temperatures, cholesterol prevents the close packing of phospholipids, enhancing membrane fluidity. Cholesterol also contributes to the overall stability and integrity of the membrane structure. Impact of Fluidity: Proper membrane fluidity is crucial for the functioning of integral membrane proteins, such as receptors, transporters, and ion channels. These proteins rely on lateral diffusion within the lipid bilayer to interact with signaling molecules, transport substrates, and conduct ions across the membrane. Membrane fluidity influences cellular processes such as endocytosis, exocytosis, and cell signaling. Changes in fluidity can affect the efficiency of vesicle formation and fusion, as well as the clustering and activation of membrane-bound receptors and signaling molecules. The dynamic nature of membrane fluidity enables cells to respond rapidly to changes in their environment and modulate their membrane properties accordingly. Cells can regulate membrane fluidity by altering the composition of lipids and adjusting the expression and activity of enzymes involved in lipid metabolism. In summary, the cell membrane is a dynamic structure composed of various lipids, proteins, and carbohydrate molecules, each contributing to its stability, fluidity, and functionality. These components work together to regulate the passage of molecules, facilitate cellular communication, and maintain cell integrity.

you literally saved my life thank you!!

Thanks very much this is really helpful

This is the very embodiment of the Feynman Technique 👍

"Put some kinks into the mix, that sounded a little weird" lmao

Seriously. Thank you!!!!

Thank you Sir.🫶🏽🇳🇬

Thank you, NINJA!!

back to the basics💪💪

You are amazing 🤩 Now I love biochemistry 😅

Such an intelligent man.

🎉the best and simple to understand❤

Please more cell biology.

Neja nerd since we need pharmacology series please

Excellent! Thank you!

Thank you so much ❤

Finally I found my teacher

Thank you so much sir :)

Please upload Remaing videos of Pharmacology on antidepressants, antipsychotics and Anesthetics

Thanks for great information

Thanks ninjanerd...it help a lot...

Adoro te, ajudas te me na universidade, obrigado ❤ Um grande abraço de Portugal 🇵🇹

Very much clear and understandable 👌 😊😊

please make lecture on spinal cord injury ... your lecture is very helpful for all of us❤️❤️

The lecture was extremely helpful like extremely ,Thankyou very much!!!!!

Extremely helpful lecture. Excellent

Good work Prof...I salute sir... enjoying the lecture from Nairobi Kenya

Really amazed by explanation ,keep it up sir for us, thank you so much Love from INDIA

Thanks a lot

Kindly make video for entire cell biology please.

You are the best ninja nerd 🎉🎉🎉

Subscribing right noww!

Your videos are superb. Tq a hundred times over.

I love this guy.

Love from Nepal sir❣️ It's a really great work

Great sir g very very conceptual

Thanks for your effort !

Awesome Lectures

✨ Dr nija can you please upload lectures about deference between osmolality and osmolarity and lecture about body fluids and osmotic equilibrium ✨

YOU ARE HEAVEN SENT!!!!

AMAZING VIDEO!!!!!!!!!!!!!!!!!!

is there a way to subscribe so that you do not see the advertising?

Can anyone explain which structures help in joining neighboring cells Glycocalyx or Integral Protein?

As always, you are a blessing...

شرحك رهيب بالكعبة

thank you sir

Thank you

Had me on the "hating life" with saturated fats on an airplane lol

Support your work Dr

Wonderful work!

Amazing ❤

KEEP IT UP, MAKE MORE VIDEOS ON BIOLOGY PLZ. IT WILL BENEFIT ALL BIOLOGY RELATED STUDENTS,ME INCLUDED