Why SGLT2 Inhibitors Cause Euglycemic DKA

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Why SGLT2 Inhibitors Cause Euglycemic DKA

Рет қаралды 8,965

Күн бұрын

Why are we seeing so much more euglycemic DKA after the introduction of SGLT2 inhibitors? In this video I will go over why so many more Type 2 diabetic patients are coming in with DKA when this disease process was previously much more predominantly seen in Type 1 diabetic patients. I will briefly review the pathophysiology of DKA (it's a helpful thing to review imo!) and then we will see how SGLT2 inhibitors end up playing a role to create a relative insulin deficiency leading to euglycemic DKA!
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Пікірлер: 27

@bfurl69 Жыл бұрын

Great video. I’m giving a presentation tomorrow on outpatient T2 diabetic meds and I got to SGLT2 inhibitors and scratched my head at euglycemic dka. Hopefully i can avoid getting pimp slapped tomorrow! 😅

@chloesmombetsey 9 ай бұрын

Currently hospitalized from this. Thank you for the clear explanation.

@nina-cy5dd 5 ай бұрын

second year med trying to refresh on this stuff before my endocrine block. thank you! you explained that so well

@ericaaguilar6537 4 ай бұрын

Ambulatory care pharmacist resident here who is going to be presenting on weather we should or should not re-initiate SGLT2i post eDKA/DKA in patients! Appreciate the clear explanation for the mechanism :D

@irrelephant0 Жыл бұрын

Really helpful! And always nice to review a little bit about DKA - I tend to always forget about it haha

@chrissem2654 11 ай бұрын

Thank you for the detailed explanation. This explanation is very helpful to understand what is going on in my body. I have just been diagnosed with EDKA caused by Synjardy to treat Prednisone indused high hba1c, which made me very sick to be admitted to the ICU. I was never a diabetic, the doctors checked my blood work for 2 years back, and there was no indication that I ever had diabetes, so the EDKA was cased by Synjardy. Thank you so much. New subscriber watching you from 🇨🇦 🇨🇦 🙏❤️

@rosedean-paccagnella5820 Ай бұрын

Nice paintings too! thanks for the explanation

@SourChip123 Жыл бұрын

As an M1, its cool listening to you talk through these topics. Do you think you would ever make a video highlighting paths to different fellowships after IM?

@malsam9668 8 ай бұрын

Thank you, very helpful. Watching this at my sisters bedside as she is in ICU with this now. She was on Jardiance.

@DuffyF56 6 ай бұрын

I just got out of 4 days in ICU for EuDKA and was also on Jardiance.

@debigdogk9563 Жыл бұрын

Great explanation, it finally makes sense. Thanks Conan ❤❤❤❤

@javadaghrab5687 Жыл бұрын

Fantastic information I have been looking for this kind of a concise and to the point answer most of the time I get bulshit for HELP. I got some time on my hands I will check out the other stuff as well

@tiffanytran4970 Жыл бұрын

Could you do a video on DKA/HHS management please? :) thank you!

@bruryrosally-dq9qw 4 ай бұрын

most article prefer the term "classical" DKA, some might prefer "typical" DKA rather than "normal DKA" to describe the most common type of DKA

@ConanLiuMD 4 ай бұрын

Love it! Thank you for that point and for keeping me updated on the more correct terminology!

@Shrivedh 21 күн бұрын

@@ConanLiuMD In my practice we're starting to move toward just calling it DKA or EKA (euglycemic ketoacidosis). Hopefully this becomes the standard as it saves 1 letter :D