We have been treating many tumors with cryoablation at our centers for almost two decades. In this video that I presented at an international congress, I tried to summarize the most common indications of percutaneous cryoablation. Today, cryoablation is being increasingly used in the treatment of many malignant and benign tumors of the breast, thyroid, prostate, kidney, liver, lung, pancreas. It is also becoming very popular in the treatment of desmoid tumors, and soft tissue sarcomas. In this short presentation, you may find different case examples of percutaneous cryoablation which may be interesting to interventional oncologists.