Certainly not a perfect run, and I'd have died many times over if not for a bit of ridiculous item luck, but I'll take it - by far my best score with Cadence. Could have been a lot higher if I hadn't run through the last few levels so fast, but I had a bit of a scare in 3-1 and was afraid of making (another) stupid mistake and losing the run.
Anyhow, #357 on the leaderboards as of this posting, and that includes runs with all characters, so I'm willing to bet the majority are using the Bard (which basically equates to 'Free Win Mode' - for those who haven't played the game, the Bard is a character that doesn't have to move on the beat - instead, enemies move when you move, like a traditional roguelike. Since enemies are almost all 100% predictable, it's extremely easy to play for score using that character). I feel pretty good about this run.