Cystic Fibrosis - Definition, Pathogenesis, Symptoms and Complications

Cystic Fibrosis - Definition, Pathogenesis, Symptoms and Complications - Genetics

Рет қаралды 126,484

4 жыл бұрын

Cystic fibrosis is an autosomal recessive genetic disease characterized by defective CFTR protein (defect in chloride channels in the sweat glands, pancreatic ducts, bronchi, bronchioles,…etc.)…Genetics lectures, Respiratory pathology.
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Пікірлер: 169

@MedicosisPerfectionalis 2 жыл бұрын

🦠Antibiotics Lectures: www.medicosisperfectionalis.com/ 📝 Download Notes: www.medicosisperfectionalis.com/

@chackojegan6868 Жыл бұрын

Bro, please don’t stop making videos, you have a gift to teach!

@MedicosisPerfectionalis Жыл бұрын

Thank you 🙏

@m.a8750 Жыл бұрын

He is just the best

@Lovemedic 10 ай бұрын

That's why he should continue 😭😭😭 he's saved my life In medical school again and again 😂😂😂

@payalnayak2176 4 жыл бұрын

No one in this world would explain such beautifully as you do it....huge respect....🙏🙏🙏🙏

@MedicosisPerfectionalis 4 жыл бұрын

Thank you so much 😊

@kaytee789 2 жыл бұрын

I love you sense of humor, you just make studying so much easier. Thank you

@MedicosisPerfectionalis 2 жыл бұрын

My pleasure 😇

@PharmAcademy2018 4 жыл бұрын

0:20 Autosomal recessive*

@MedicosisPerfectionalis 4 жыл бұрын

You’re right...It’s Autosomal recessive 😊

@zannatul23 3 жыл бұрын

rookie mistake

@AbdulHameed-lc8xi 4 ай бұрын

you know what i took 5 difference lectures to understand CF pathophysiology but i couldn't . But you just aced it ❤😭

@MedicosisPerfectionalis 4 ай бұрын

I am honored! Please help me by sharing my videos with others!

@Adam-franka 3 жыл бұрын

What a nice illustration , thank you and keep up the great work.

@joelnendongo1959 4 жыл бұрын

wonderful explanation

@dastaniam 2 жыл бұрын

I actually understand you better than my professor, you're really the best ❤️

@MedicosisPerfectionalis 2 жыл бұрын

Thank you 😊

@diannahichez7349 3 жыл бұрын

Thank you so much it is very helpful. I am not sure why my textbook says leading cause of mortality is Respiratory Failure. In your video you stated it is Pneumonia .

@dr.ishasingh9333 4 ай бұрын

You are a gem man!! So crisp!!

@CFlifestyleFoundation Жыл бұрын

Thank you for making this video, and for helping spread awareness of this rare disease and the people who are affected by it.

@MedicosisPerfectionalis Жыл бұрын

Thank you!

@dr.reinholdthaler8948 4 жыл бұрын

Just great as Always.I Love watching your Videos between two operations and asking the residents questions about General medicine to enlight their mind.Looking Forward to your next Video tomorrow.

@MedicosisPerfectionalis 4 жыл бұрын

Awesome...That’s excellent...I am honored, sir

@user-uh1qm4gs6v Ай бұрын

You are so helpful please don't stop to make more video ❤❤❤ thank you so much

@samishawanchoo3316 3 жыл бұрын

Amazing lecture sir👍🙌

@mahnoor7726 Ай бұрын

Never really got this topic until today… You’re my faavouriteee

@MedicosisPerfectionalis Ай бұрын

Thank you so much!

@nicolegoldberg9757 4 жыл бұрын

Thanks! Finally understand why CF is an obstructive lung disease rather than restrictive. Was confused by “fibrosis”. Thanks for being so funny as well!

@MedicosisPerfectionalis 4 жыл бұрын

Haha 😂 Thank you so much for watching! I am so glad that my video helped!

@ThatsWhy- 2 жыл бұрын

Bravo, very amazing teacher. I am educated ; learning and unlearning and relearning scientific subjects !

@MedicosisPerfectionalis 2 жыл бұрын

Wow 🤩 Thank you 😊

@victoriahoma5094 2 жыл бұрын

So easy to understand , you’re literally a breath of fresh air from textbooks , thank you 🤍

@MedicosisPerfectionalis 2 жыл бұрын

My pleasure 😇

@farihafathima7741 Жыл бұрын

Gotta love your explanations, some of them really crack me up! Thankyou for making medicine perfect and funny

@MedicosisPerfectionalis Жыл бұрын

You’re very welcome 😊

@nsas955 Жыл бұрын

Thank you very much...this is the best time I understood cystic fibrosis. You are a genius indeed.

@MedicosisPerfectionalis 11 ай бұрын

I appreciate you so much! Would you please help me by sharing?

@mohannadabdulkareem4626 2 ай бұрын

What is the app u use to produce such great educational vedis like this ? Tell us please

@yannur6841 3 ай бұрын

Sir you are a gift to the world, this, as all the reat of your work - is beyond amazing!

@MedicosisPerfectionalis 3 ай бұрын

Thank you!

@marijamijakova3992 3 жыл бұрын

I wish I had professors that have a teaching technique similar to yours. Life would be so much easier. Thank you, sir!

@MedicosisPerfectionalis 11 ай бұрын

Thank you so much!

@drSJV Жыл бұрын

So excellent! Thank you!

@MedicosisPerfectionalis Жыл бұрын

My pleasure 😇

@ilhom83 2 жыл бұрын

love your videos I am PA Student graduating in few month, I can not even imagine what I would've done during my didactic year without your lessons. I am finishing my clinical year and still use your videos to review. Great video only one little mistake on 20sec CF is autosomal recessive NOT Autosomal dominant. As always flowless video very funny and informative. Please continue uploading your great videos.

@MedicosisPerfectionalis 2 жыл бұрын

Thank you 🙏 Yes, you’re correct! Cystic fibrosis is autosomal recessive!

@luisamartin662 11 ай бұрын

You're amazing! Thanks!

@MedicosisPerfectionalis 11 ай бұрын

My pleasure!

@mohammedamir7197 3 жыл бұрын

You are more than genius man

@MedicosisPerfectionalis 3 жыл бұрын

Thank you so much 😊

@sohaimsahi3641 Жыл бұрын

Excellent job

@MedicosisPerfectionalis Жыл бұрын

Thank you 🙏

@MedSurvival 4 жыл бұрын

That's was very informative and helpful. ❤️❤️❤️❤️

@MedicosisPerfectionalis 4 жыл бұрын

I am honored

@user-mv3hz9xc4l 2 жыл бұрын

Hi.. thank for your information.. i would ask you if there is a textbook you take these nice information from .. like in the vedio , it would helps alot ..

@abdomoein 2 жыл бұрын

Thank you so much, this helped a lot

@MedicosisPerfectionalis 2 жыл бұрын

My pleasure 😇

@esrah8151 Жыл бұрын

Thank you, I would like to comment regarding the mode of inheritance for cystic fibrosis is autosomal recessive👍🏻

@MedicosisPerfectionalis 11 ай бұрын

Correct!

@brush-upwidme2687 4 жыл бұрын

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@MedicosisPerfectionalis 4 жыл бұрын

You're very welcome 😊 Can you please help me by sharing?

@brush-upwidme2687 4 жыл бұрын

@@MedicosisPerfectionalis sureeeeee♥️..I will🙌💪

@MedicosisPerfectionalis 4 жыл бұрын

Thank you 🙏

@bhargavkanabar2792 4 жыл бұрын

Your teaching technique is very impressive and I am watching your each and every lacture You are cover whole information of specific topic Great job I appreciate you 👍🏻

@MedicosisPerfectionalis 4 жыл бұрын

Thank you so much 😊

@bhargavkanabar2792 4 жыл бұрын

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@MedicosisPerfectionalis 4 жыл бұрын

You can email me

@bhargavkanabar2792 4 жыл бұрын

Give me Email address and Instagram ID

@MedicosisPerfectionalis 4 жыл бұрын

medicosisperfectionalis@gmail.com Instagram: search Medicosis Perfectionalis

@mayamazz978 2 жыл бұрын

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@MedicosisPerfectionalis 2 жыл бұрын

My pleasure 😇

@sashahanna3792 3 жыл бұрын

Awesome video.Cystic Fibrosis is Autosomal Recessive Disorder.

@MedicosisPerfectionalis 3 жыл бұрын

You’re right

@wajeehashah7103 Жыл бұрын

Awesome video 😍

@MedicosisPerfectionalis Жыл бұрын

Thank you! Would you please help me by sharing?

@wajeehashah7103 11 ай бұрын

@@MedicosisPerfectionalis sure bro

@kazhankamal8340 4 жыл бұрын

Ohhh i wish every thing good for you inlive god help you ,make u happy ,rich every thing u want in your life , thanks alot for shareing your talent/knowledge/ intelligence in teaching with us , things much more easier with your lectures, because your aim is to make us understand the lecture not for increasing your subscriber or your financial just like some other that just reading or saing smt and then ending the videoo😇😇😇😇✨✨✨✨✨✨✨ Note: im from kurdistan /iraq near your country 🙃😃😉

@MedicosisPerfectionalis 4 жыл бұрын

Thank you so much 😊 I appreciate it!

@solomonawobem8420 2 жыл бұрын

You are the BEST

@MedicosisPerfectionalis 2 жыл бұрын

Thank you 😊

@Nicu-Live Жыл бұрын

loved your videos ❤️

@MedicosisPerfectionalis Жыл бұрын

Thank you 😊

@keratinpearls5058 2 жыл бұрын

U have made me fall in love with medicine n you

@imtinan7136 3 жыл бұрын

I owe you a lot 🙌🏻😭

@MedicosisPerfectionalis 3 жыл бұрын

Thank you 😊

@kathmandunepal9547 3 жыл бұрын

How is Chloride secreted from the sweat gland into the skin if there is no CFRT channels in CF?

@drimranortho5526 3 жыл бұрын

Sir in CF, there is congenital absence of vas deferms.

@brk0093 4 жыл бұрын

Hii my frnd.. once again a awesome video ...keep on rocking

@MedicosisPerfectionalis 4 жыл бұрын

Thanks 🙏

@ionabanerjee519 2 жыл бұрын

Thanks for the video. I thought CF is autosomal recessive, isn’t it?

@shampaviganaikabahu8440 Жыл бұрын

Cystic fibrosis is autosomal recessive

@OkonkwoMartins 6 ай бұрын

I believe he made a mistake at the beginning when he said "Autosomal Dominant"

@OkonkwoMartins 6 ай бұрын

At 1:38, he states it's Autosomal Recessive

@user-pj6fp9st7d 3 жыл бұрын

"let's go back to the good old days that were not so good.." I love your videos so much!!! HAHAHA what a great teacher, thanks for everything you do

@MedicosisPerfectionalis 3 жыл бұрын

Thank you so much, dear!

@aimset4178 4 жыл бұрын

What about cholera incident in cystic fibrosis ? What cholera symptoms happen in c f patient? Tell me please

@mahsamazdak2755 21 күн бұрын

Cystic fibrosis is more common in north Europe cause vibrio cholerae used to be common there and people with cystic fibrosis are immune from cholera infection and related death. Natural selection!

@lilianafernandes294 Жыл бұрын

you're videos are great! ALERT: sec 18-22 "cystic fibrosis an autossomal dominant disease".. ups :) it happens... keep your excelent work

@MedicosisPerfectionalis Жыл бұрын

It's autosomal recessive! Sorry about the mistake!

@biswajitbanik6803 3 ай бұрын

Can you tell me about Meconium ileus, is it related with CF? i lost my first child with Meconium ileus ..what is the repetition Chance??

@okk2101 6 ай бұрын

Great!!

@Zetsuke4 4 жыл бұрын

Thank you

@MedicosisPerfectionalis 4 жыл бұрын

My pleasure 😇

@argumentumadbaculum 4 жыл бұрын

Hi its great how you worked out the carrier rate, would you be able to show how we can plug the numbers in Hardy weinberg equation Kind Regards

@MedicosisPerfectionalis 4 жыл бұрын

That’s a great idea. We will discuss that in Genetics later. Thanks 🙏

@argumentumadbaculum 4 жыл бұрын

@@MedicosisPerfectionalis thanks a lot for your prompt answer. figured it out, was doing a rookie mistake of finding the the squareroot of the fraction instead of solving square root individually.

@user-jm2uf9rr5k Ай бұрын

I'm watching this on 2× and prof is about to take a quiz about cf Edit: I can't thank you enough medicosis

@kehindeolayinkaolaposi8426 2 жыл бұрын

The mode of inheritance of Cystic fibrosis is Autosomal recessive. Again, not 25% of the offsprings, rather per pregnancy, there is a 25% change of offspring being a carrier 25% change of the offspring being affected by CF and 50% chance that the offspring will be normal. That's if both parents are carriers.

@ThatsWhy- 2 жыл бұрын

Can the left lung compensate for the lost O2 of the right lung? In case of CF

@nooral-jaberi2938 2 жыл бұрын

Hi, thanks for your videos , can you please check , I believe cystic fibrosis is Autosomal recessive disease not Autosomal dominant disease ?

@MedicosisPerfectionalis 2 жыл бұрын

You’re right!

@nidaayub1338 5 ай бұрын

Hello. Would just like to point out that this disease is actually Autosomal Recessive than autosomal dominant. Might wanna check that out. Thanks. :)

@MedicosisPerfectionalis 5 ай бұрын

You’re correct! I mis-spoke!

@swarooproy9001 Жыл бұрын

Great!

@MedicosisPerfectionalis 11 ай бұрын

Thank you!

@cplson2706 4 жыл бұрын

Another great video. 👌

@MedicosisPerfectionalis 4 жыл бұрын

Thanks 🙏

@allamalik4209 4 жыл бұрын

Duh , ur genius😂❤thank u alot

@MedicosisPerfectionalis 4 жыл бұрын

My pleasure 😇 Can you please help me by sharing?

@syuhadaafiqah 4 жыл бұрын

“Duh I’m genius” 😂 btw this really helped me to find more infos on my Problem Based Learning session in college. Thanks!

@MedicosisPerfectionalis 4 жыл бұрын

You’re very welcome 😊

@manlam4847 3 жыл бұрын

I hate PBL

@syuhadaafiqah 3 жыл бұрын

@@manlam4847 HAHAHAA but why

@manusid Жыл бұрын

At 5:35 . The language used is "One out of 4 kids will have cystic Fibrosis". Shouldn't it be- each kid when born, has a 25% chance of having CF .?? After all these are only possibilities as you said.

@osamamahmoud7238 Жыл бұрын

CF, autosomal dominant ?

@Nini-os2yv 2 жыл бұрын

Pancreatitis with CF chronic or acute?

@hawanuradin4147 4 жыл бұрын

Thank you dr.

@MedicosisPerfectionalis 4 жыл бұрын

My pleasure 😇

@ula7254 9 ай бұрын

That maths though passed over my head 😅😂

@jringo45acp 6 ай бұрын

The fibrosis part of CF in the lungs is scar tissue.

@shahadj3474 Жыл бұрын

It’s very rare to happen DKA in CF patient

@shruthikarthikeyan1227 2 жыл бұрын

Awesome as usual! I have a doubt.. nacl is increased in sweat so v get salty sweat in CF right.. but u mentioned hypotonic fluid is lost in sweat so contraction alkalosis occurs.. can u please explain? 😅

@rahandsoran2588 2 жыл бұрын

This man’s jokes are golden

@Lovemedic 10 ай бұрын

Not me paying attention to know why it's common in Nothern Europe 😂😂 He always have jokes!😂😂

@abdulrahmanalomair5668 3 жыл бұрын

I love you

@medico1012 4 жыл бұрын

It’s like someone reading my lecture for me👍🏼

@MedicosisPerfectionalis 4 жыл бұрын

Haha 😂

@amneetkaur5198 4 жыл бұрын

❤

@MedicosisPerfectionalis 4 жыл бұрын

😊😊

@fastfoodforthought584 2 жыл бұрын

“1 out of evry 4 kids will get cystic fibrosis “should have been “the probability of a kid having cystic fibrosis is 1/4”no??

@medstudent585 Жыл бұрын

You said autosomal dominant in the beginning but then you said recessive *

@MedicosisPerfectionalis Жыл бұрын

It’s recessive!

@medstudent585 Жыл бұрын

@@MedicosisPerfectionalis 👍🏻👍🏻thanks for the video!

@asmaanjum5562 Жыл бұрын

It’s an autosomal recessive disease

@MedicosisPerfectionalis Жыл бұрын

Yes!

@nargiznargiz4907 2 жыл бұрын

Why cystic fibrosis is in a high rate among north caucasians? Becaof lots of close relative marriages. I know lots of people whose moms and dads are close relatives like cousins. By the way I am caucasian. My parents are relatives and I do scold them sometimes)))))

@venkataraoyamavaravu7246 Ай бұрын

@AmanduhFlawdHog 4 жыл бұрын

Cystic fibrosis is living flip to kids it should be focused on more than it is right now alongside diabetes, the more with cf the more diabetes because a higher risk for the c.f. Kid is put on the line with diabetes these people don't realize c.f. Is way more complicAted then doctors like to see we need better doctors and nurses pt and treatments, how do I know this you ask?? I have it.

@MedicosisPerfectionalis 4 жыл бұрын

I am so sorry to hear that