On July 21, 2021 the DC CFAR Basic Sciences Core Hosted an Open House that served as a training seminar focused on the Orbitrap Exploris 480 Mass Spectrometer. It included a presentation by Thermo Fisher Scientific Specialist Christopher Bolcato, featuring its uses for quantitative and single cell proteomics. Proteomics workflow and Proteome Discoverer 5.0 data analysis program was also discussed.