My baby sister, River has ASA she is doing well but can't have much protein at all. She is 11 months old and standing almost walking. Please wish her luck in life knowing she might not have the life we anticipated for her 💖

You breakdown complex reactions in such a way that it no longer fells complex. HATS OFF for the effort you put for that.👍👏

Doctor's comment: excellent explanation, very comprehensive, and well organized. Fan girl comment: How do I marry you and your brain?! 😍😳😛

i wonder why he doesn't have a lot more views, but anyways i rlly liked the way that you explain things! Also, your drawings and organization makes me jealous hahaha Congrats and Thanks! :)

Finally what I have been looking for. I can't thank you enough for this. Liked and subscribed.

YOU ARE JUST THE BEST AND ONLY THE BEST IN EXPLAINATION

Best presentation, simple , concise and to the point..Thank you ❣

very well done,Alhumdullilah you explained it fully and indeed it is conceptual.

Very beautiful explanation. Thank you very much.

you are excellent . we need people like you.

Thank you sir for ur invaluably simple explanation.

Excellent video !

You are making med studs life easier, can u pls make a video regarding microsomal oxidation?📹

Beautiful explanation. Had fatigue and brainfog for 3 years sudden onset. Was deficient in Ornithine, Citrulline and BCAAs, but had hight Arginine. Amino Acid therapy helped a bit. Still have brain fog but docs cant figure out the cause since my organs look fine, my liver too. I dont have OTC deficiency (23and me showed that), so we don't know what caused the amino acid deficiency despite a high protein diet. Taking BCAA help me not to lose weight. Don't know if I should take glutamine, my docs know nothing about that.

I dont know how to thank you enough

very nice...well expounded and comprehensive lecture.thumbs up 👍👏

I got hyperammonemia from depakote (valproic acid, seizure medication) and almost died from it. Epic experience.

Cool lecture. A doubt why are we getting rid of glyine> How does hyperammonemia lead to a rise in glycine levels.. is it just that are trying to get rid of the amino acid pool in the body or just that we have a mechanism of excretion of hippurate so we make use of glycine

Great presentation and leaves me curious why nitric oxide wasn't part of this cycle. Also is Urea another possible way to treat a cycle defect and why is Glycine a problem? And what about Keto Acids binding to Ammonium for safe removal?

You are a genius!!! Thank you

very nice sir......but u should zoom on the writhing so that we can see whats written......please write a bit larger......(sorry 4 my bad eng)

Great vid keep up the stella work you star

Nice sir!

So what does it take to make, lets say the carbomoyl phosphate synthelase enzyme work? Any minerals etc that support this function?

Adding exogenous arginine for arginosuccinase deficiency makes no sense. Given your explanation, adding ornithine would make sense. Furthermore, you must mention the vitamin, mineral cofactors.

Why high level of glutamine is sought in bodybuilding industry then? It needs to be corrected.

how does the body get rid of excess arginosuccinate?

very graet

Thats my nightmare right now 💔😥😥😥😥😥😥😥😥

Sir I have a question related to clinical significance of urea cycle ! So can I add these disorder that you have added in this video ? Help me

2:48 reaction

Arginine supplement does help with Ornithine Transcarbamylase Deficiency, apparently*

Does this mean excess glutamine is adverse to our body?

For argininosuccinase deficiency, can we treat the patient by using ornithine replacement instead of arginine?

Respect

how do you reverse a fatty liver?

why I did not find you earlier 😭

Plx made this lecture in Urdu

is hyper ammonium fully curable if diagnosed in infants

🙏🙏🙏

Could someone Translate this in danish???? 🙏🙏🙏💖

من اجل نزوه لا تتجاوز بضع لحظات يولد انسان ليشقى من ستين الى سبعين عام 😃الامور قد تبدو عبث ولكنها سنة الحياه ، فى بداية الامر حيوان منوى من الاب يندمج مع حيوانه منويه من الام 😁ثم تحدث عدة انقسامات وتحوارت شكليه وتمايزات جسديه فى رحم الام طيلة 9 اشهر ليولد طفلا ضعيفا هشا ثم يكتسب من بعد ضعف قوه واخيرا فى النهايه من بعد قوة ضعفا على النمط التالى طفل ضعيف >شاب مغرور بقوته >واخيرا كهل عجوز لو طبقنا هذا على واحده من اهم موجبات الحياه للإنسان لكانت مثالا مطابقا لحياتنا اولا الحيوان المنوى هو الCO2 والحيوانه هى الNH4 😁يندمجا معا ليتكون الطفل الCarbamoyl phosphate يتمايز ويكبر داخل رحم الام حتى يكتمل تمام يخرج الى الحياه وهى (cytoplasm ) على هيئه citrulline هذه المرحله كلها داخل رحم الام وهى ال mitochondrial matrex 😉اما بدايه الحياه تاخذ الام هذا الطفل الرضيع الضعيف ال citrulline وتغذيه بالaspartate حتى ينضج ويصبح فى سن ما قبل البلوغ اى قبل الاعتماد على النفس وهى الargininosuccinate حيث كلمة argi تعنى ما وكلمة nino قبل وsuccinate تعنى البلوغ وهذا من معجم اللغة الزومبيه الوجيز 😂يريد الطفل المميز اى القادر على تميز الاشياء ان يتحرر من سطوة والديه الى اكتشاف قدراته ومهاراته وهى فترة المراهقه فيفقد حنان والديه على هيئة fumarate ليصبح شابا ناضجا فى ريعان شبابه اسمهarginine ثم بعد الشباب يفقد قوته وهى الماء H2O ومن الماء الحياه فاذا فقد فقدت الحياه يدخل الماء على الشاب العفى Arginine ويتركه وهو عجوز كهل وهو ornithine ويعطيه ولدا اسمه الurea ليعيد دورة حياة ابيه هذا كله فى الcytoplasm ويقولون فى الامثال لفى بينا يا urea دوخينا يا urea خدينا يمين شويه خدينا شمال شويه وادينا عايشين يا urea 😂وشكرا 😃