Direct-Acting Oral Anticoagulants (DOACs) | MOA , Indications, Adverse Reactions, Contraindications

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Direct-Acting Oral Anticoagulants (DOACs) | MOA , Indications, Adverse Reactions, Contraindications

Рет қаралды 81,955

Күн бұрын

Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
Join us for our Pharmacology lecture on direct-acting oral anticoagulants (DOACs). During this lecture Professor Zach Murphy will guide you through the mechanism of action, indications, adverse drug reactions, and contraindications involving direct-acting oral anticoagulants (DOACs).
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#ninjanerd #DOAC #pharmacology

Пікірлер: 117

@donnamaeabarintos7422 3 жыл бұрын

Pharmacist here! You're the best pharmacology lecturer! Thank you Zach :)

@abdulformouli4894 Жыл бұрын

😊😊😊😅😅😊 11:24 11:25 11:26 😊😊

@abdulformouli4894 Жыл бұрын

13:02

@abdulformouli4894 Жыл бұрын

I’m 13:21 13:23 😊😊😊 14:02

@CameronGhassemi 4 жыл бұрын

Bro, why you so clutch all the time with these perfectly timed posts! Thank you!

@daviddivineful Жыл бұрын

I am a RN who works on a CV IMU. These videos are always informative. Many of my fellow RNs are also NPs. Even they tell me they watch the Ninja Nerd videos when I mention Zach. Thanks for being an absolutely solid teacher.

@heythere8577 4 жыл бұрын

Yay ! Finally understanding new things !! Thank you so much for everything ! Love you ! Stay healthy !!

@abdulformouli4894 Жыл бұрын

One of the best lecture. Clarified my confusion and my thoughts about DOA

@choozomano977 4 жыл бұрын

Thanks a lot for coming back 💝 U r an amazing teacher! Respect u a lot.

@abdulkabir.3557 4 жыл бұрын

Good job sir .your teaching methodology is so amazing and best . easyly capture by brain .

@jayshreeshah9739 3 жыл бұрын

Thank you so much for your explanations! They are the best.

@abdifitahmohamed4159 2 жыл бұрын

I don't always comment of KZfaq videos But I just wanna say thank you so much for all your efforts, Your teaching methods are outstanding.

@mohamedsherif9088 Жыл бұрын

I rarely comment for someone but you are a life saver thank you zach

@louisaj4122 2 жыл бұрын

Thank you so much! You are such a blessing to students like me ☺️

@lilianechick904 7 ай бұрын

I can't stop watching your videos, even though I'm studying for the Nursing exam (NCLEX). Your videos are so complete and I really appreciate it.

@saddiqanaeem9028 Жыл бұрын

Beautifully explained. Million thanks for such great effort.

@haleycstudentpharmacist3879 3 ай бұрын

This video saved me before my applied therapeutics case. Thank you so much!

@nish209 4 жыл бұрын

Jheeze Rollin out the videos ... really grateful. Keep em coming

@sweetyverma3015 4 жыл бұрын

Really..for the 1st time understood this topic.. make sm more lect in pharmac

@muhammadashfaq6403 2 жыл бұрын

a very useful n comprehensive lecture indeed and also practical

@fionabeagle5467 Жыл бұрын

Your teaching style is amazing

@drjuloo 4 жыл бұрын

oh my lord im your fan!! thanks for the videos!! really helped me a lot 💛

@royarastegar6421 3 жыл бұрын

Thanks a million times for all your efforts. Your teaching methods are outstanding!

@kunjanpatel5580 2 жыл бұрын

You are a legend 😊 Thank you so much for doing this.

@evelynaguila9642 Жыл бұрын

awesome presentation, as always.. keep it up!

@gabrielerklart1470 4 жыл бұрын

Keep up the good work!! Cheers from Germany!

@bradwarr7570 4 жыл бұрын

Super clear video as always ninja master 😀👍

@khonagok1584 Жыл бұрын

You are the best doctor I love all ur videos

@drsinaaalbazii629 4 жыл бұрын

thank you for a great way of teaching,

@palshah3509 2 жыл бұрын

THANK YOU NINJA NERD TEAM 💖💖💖💖💖

@neelo14 4 жыл бұрын

Thank you sir. All your videos are awesome. 👌

@benzylbenzoate7208 4 жыл бұрын

Keep the pharmacology video coming!

@shafranajimudeen3104 Жыл бұрын

Again I'm here during my end sem study leave,!! Thank you sir😍

@oreskoul 2 жыл бұрын

very helpful, thank you once again !

@latifabouabdallah6746 4 жыл бұрын

Thank you. U just made it easier 🙏🙏🙏🙏

@KCMDWannabe 4 жыл бұрын

Awesome stuff guys thanks a ton

@MelOloughlin 3 жыл бұрын

Great video! Thank you!

@missionexpired3618 4 жыл бұрын

How lucky I'm. I will be having exams on this topic, Thank you

@1peteranswers 2 жыл бұрын

Helping me out in the cathlab! Thanks

@legendlegend1621 4 жыл бұрын

I can say that my grades in medical school are thanks to your videos .. I don't know how to thank you

@cooltroop2 4 жыл бұрын

Thank you, King!

@h.q.1736 3 жыл бұрын

Excellent ,thank you so much

@biologygeneandbiochemistry1654 4 жыл бұрын

Thank you zach.

@Raisa-wm4wx 24 күн бұрын

Thank you much.

@mariepenrod1550 Жыл бұрын

Love your video

@serge6886 2 жыл бұрын

Step 3. And I’m still watching this beauty hahaha.

@donalddavis303 3 жыл бұрын

These are great

@sarahsahibqran2198 4 жыл бұрын

Surprise surprise, another amazing video by the king🤴. Please please please do videos on bone structure, remodelling and fracture healing pleaseee!!

@arunadhikari5137 4 жыл бұрын

Thanks alot . you are the best

@morganasasso1924 2 жыл бұрын

thank you

@snnnaanya7673 4 жыл бұрын

Thank you for your great efforts , I have a suggestion, can you please list in description box the names of textbooks and references used in helping to make the content of each video from now on ? It would be very helpful when deciding to go over the details that weren’t mentioned in the videos , I hope to take this step in consideration next time 👍🏻

@Zetsuke4 4 жыл бұрын

Hi hi I love you. Thanks for this video!

@Be1smaht 2 жыл бұрын

So so so interesting

@rayyaalghazali5349 2 жыл бұрын

Best of the best

@sarahsahibqran2198 4 жыл бұрын

Do a video on secondary bone healing and endochondral vs intramembrenous ossification pleaaase!! 🙏🙏🙏

@denised3956 3 жыл бұрын

you're AMAZING!

@georginahanna8344 5 ай бұрын

Thank youuu love uuuu ❤❤❤

@haru-qy3sz 4 жыл бұрын

Sir I'm a huge fan..

@salmataia9891 4 жыл бұрын

Thank you a lot .. 🌷🌷

@qazal1116 3 жыл бұрын

Thanks a lot 😍

@istreamkerala1 2 жыл бұрын

Awesome ❤️❤️❤️❤️

@muhammadikrama9286 4 жыл бұрын

I love your videos 🖤.

@zofiakolwicz6808 2 жыл бұрын

Thank you so much!!!

@sleepydumdum6074 2 жыл бұрын

thanks bro

@shahiramohammadi7284 3 жыл бұрын

Awesome

@medicallifewithjohn 3 жыл бұрын

awesome

@strlucii 2 ай бұрын

Mulțumim!

@shivalikatal5839 3 жыл бұрын

Thankew you are an legent ❤

@cya915 2 жыл бұрын

@lillianotuokwu5800 2 жыл бұрын

great💖

@darleen6258 3 жыл бұрын

Perfect Perfect Perfect Perfect Perfect Amazing Amazing Amazing Amazing Amazing. We love you ninja nerd 🥰🥰🥰🥰❤❤❤

@mdsanwarhossain8236 4 жыл бұрын

Tnx

@mfalaksheikh7804 4 жыл бұрын

appreciate !

@divyaarora5492 Жыл бұрын

Hey great video! Could you please reply to this: why do we give warfarin in valvular A. Fib??? Why not DOACs??

@saiteja6742 4 жыл бұрын

Do video on antileprotic and antimalaria sir

@beatrizribeiro6038 3 жыл бұрын

u is amazing

@annaflores4322 3 жыл бұрын

Learning to love pharmacology. #NN4LIFE

@sag1565 4 жыл бұрын

SUPER

@earlkoh216 3 жыл бұрын

Noacs aren't contraindicated in ischemic stroke. They are the main stay of tx in ischemic stroke with af. That being said, you should stop all anticoags and antiplatelets if they have haemorrhagic conversion Thanks for the great video

@wahib786 4 жыл бұрын

Love from INDIA🔥🥰

@ZahraaSalam-em4ws 2 ай бұрын

How can we choose any one of factor Xa inhibitors to use if it was indicated ??

@UbaidKhan-sr6ew 4 жыл бұрын

Sir plz do some portions of embryology like urogenital system deleopment and much more

@aluminiumknight4038 4 жыл бұрын

www.patreon.com/NinjaNerdScience

@sunkarilakshmi2551 2 жыл бұрын

🔥🔥🔥

@UbaidKhan-sr6ew 4 жыл бұрын

Sir plz do embryo.

@RBA13u 4 жыл бұрын

Great job as always but how can you say FXa Inhibitors have more bleeding than Dabigatran and Warfarin? Literature is clear especially RCT's against Warfarin that there is less bleeding.

@Be1smaht 2 жыл бұрын

1. This is coagulation cascade - stops bleeding 2. Factor X on its own will amplify the result by activating many fibrins and stabilizing the clot 3. Because it is upstream it will affect many clots vs. thrombolytics for thrombin that affect a single clot

@Be1smaht 2 жыл бұрын

Not sure on Warfarin

@peterlearner8594 3 жыл бұрын

You say stopping blood thinners abruptly is dangerous without explaining. Is the risk of clotting after discontinuance greater than if the patient never took the anticoagulant or does the risk of adverse event simply return back to exactly the same level as pre coagulation? Is this danger of suddenly stopping anticoagulation only confined to long term use or short term use or on as need basis? Or is the danger of sudden cessation only in regard to those that have had a thromboembolism within the last 3 months? Also, can factor IIa inhibitors be used for anything else other than cardioversion?

@shoqalshammri8542 4 жыл бұрын

I miss u ❤️❤️❤️❤️

@SMILE-vc5he 4 жыл бұрын

Please, i have a question that desturbing me? Why there is no survey when we use this medications? They have the same effect of heparine but why we do not have blood control via PT? Is that because of less risks of bleeding? But Revaroxaban still have this risque so why do not we test the anti- Xa ?

@mariepenrod1550 Жыл бұрын

What if patent has dialysis and has had hemorrhages of brain before, what is best if has led clot, after they have him tons of heparin?

@mariepenrod1550 Жыл бұрын

Leg clot

@Be1smaht 2 жыл бұрын

What don't I understand is why give Thrombin inhibitors for DVT and PE? Why not give fibrinolytics?

@nurmohammadchowdhury_roll_7636 Жыл бұрын

Isnt bivalirudin a iv drug?

@SG-xb7de Жыл бұрын

My mom has been prescribed Cordarone & Evion LC by her Cardiologist, while her Neurologist added Apixaban These are all twice a day. Since she started taking Apixaban, she's now spitting blood (approx half tea spoon bloody saliva) every night, day she's fine. Despite knowing about blood, Neurologist told that stopping Apixaban can cause stroke. My guess is that Cordarone, Evion & Apixaban are reacting. She doesn't get blood when she skips Apixaban. She takes all with food. Is my analysis of reaction correct? Is there a better way to consume these medications safely? How worried should I be for her spitting little blood every night? Please answer. Thanks!

@davidecornella3889 Жыл бұрын

I can only claim that there is an interaction between these 2 drugs. Amiodarone increases the effects of apixaban through inhibition of CYP system and P-glycoprotein

@UbaidKhan-sr6ew 4 жыл бұрын

Sir plzz upload embryo lectures

@aluminiumknight4038 4 жыл бұрын

www.patreon.com/NinjaNerdScience

@blackyrocky7438 2 жыл бұрын

I don’t understand why thrombin is needed for factor five to activate thrombin. Is inactive form of thrombin is always there in our blood ? Are these all clotting factors circulating in our blood in inactive form? Is factor five needs inactive form of thrombin to activate thrombin?

@Be1smaht 2 жыл бұрын

I think its an amplified effect.

@sithuminichathunika5425 Жыл бұрын

❤

@parijatchakraborty8765 4 жыл бұрын

Can you pls make videos on microbiology, bacteriology plsss????

@aluminiumknight4038 4 жыл бұрын

www.patreon.com/NinjaNerdScience

@aluminiumknight4038 4 жыл бұрын

www.patreon.com/NinjaNerdScience

@zia735 2 жыл бұрын

King

@natnaelhailu442 Ай бұрын

👍

@georginahanna8344 4 жыл бұрын

Hello, I'm a second year medical student I made it out the first year with a 95% percentage thanks to you, now I'm a second year. Could you please tell what references do you use? Also I love your channel, you're a Life Savior thank you very much.

@AceKinG2024 4 жыл бұрын

Hello. Are you lebanese?

@georginahanna8344 4 жыл бұрын

@@AceKinG2024 Half Lebanese actually, how come?

@faisalmanan1769 4 жыл бұрын

I appreciate your cleary insight videos and i love it im expecting video about CORONA VIRUS video what exactly pathogenesis i wish i could see this video from yoi Thanks and Salute you👍