Recent years have seen a huge surge of interest in oligonucleotide therapeutics, fueled by major advances in our understanding of how to make such molecules stable, selective, and efficient as drug modalities. The field is now diverse in terms of therapeutic areas being addressed, biological processes being manipulated and delivery technologies employed. This webinar will present recent developments in oligonucleotide chemistry, biology, and DMPK.
Our speaker panel of experts are involved in providing state of the art technical support to the discovery stages of an oligonucleotide therapeutic program. They will review the synthesis and modification of oligonucleotides, design and execution of suitable in vitro and in vivo assays, and methods for determining pharmacokinetic parameters. Finally, our expert panel will be available for a question-and-answer session.
Key Learning Objectives:
Examine the synthesis and modification of oligonucleotides
Explore methods for determining pharmacokinetic parameters
Hear about state-of-the-art discovery strategiesS