DNA Structure and Replication: Crash Course Biology #10
Рет қаралды 9,620,412
12 жыл бұрынHank introduces us to that wondrous molecule deoxyribonucleic acid - also known as DNA - and explains how it replicates itself in our cells.
References:
www.nature.com/nature/dna50/wa...
publications.nigms.nih.gov/the...
rst.gsfc.nasa.gov/Sect20/A12.html
www.nature.com/scitable/topicp...
www.uic.edu/classes/phys/phys4...
www.buzzle.com/articles/dna-re...
www.dnareplication.info/stepso...
salamandercandy.wordpress.com/...
www.sdsc.edu/ScienceWomen/fran...
www.fmi.ch/members/marilyn.vac...
www.strangescience.net/rfrankl...
1:41 link to Biological Molecules • Biological Molecules -...
Table of Contents:
1) Nucleic Acids 1:30
2) DNA
-A) Polymers 1:53
-B) Three Ingredients 2:12
-C) Base Pairs 3:45
-D) Base Sequences 4:13
3) Pop Quiz 5:07
4) RNA 5:36
-A) Three Differences from DNA 5:43
5) Biolography 6:16
6) Replication 8:49
-A) Helicase and Unzipping 9:22
-B) Leading Strand 9:38
-C) DNA Polymerase 10:08
-D) RNA Primase 10:24
-E) Lagging Strand 10:46
-F) Okazaki Fragments 11:07
-F) DNA Ligase 11:47
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@pedrosmith4529 5 жыл бұрын
My earphones get tangled all the time, but miles and miles of DNA don't. Mind blowing.
@vjlove1218 5 жыл бұрын
Stan Lem yes! But DNA has a LOT of help from many different proteins
@its_tomothy 5 жыл бұрын
For some reason, I read that as "My earlobes get tangled all the time" :0
@lalaithan 5 жыл бұрын
@@its_tomothy do your ears hang low? Do they wobble to and fro?
@its_tomothy 5 жыл бұрын
@@lalaithan yeah, im actually dobby the house elf lol
@ddbrayen1aramai1tii 5 жыл бұрын
Its actually tangled and become 3D coumpound
@her1468 Жыл бұрын
11 years later, the video still better than a two hour lecture
@rheasharma2939 6 жыл бұрын
Hank: "Hey you wanna make one?" Me: I'm 12
@mattalex543 5 жыл бұрын
This dude is getting me through college one video at a time.
@lilzod4862 4 жыл бұрын
College?!? Bruh what kind of college you in?
@zoefoster6750 4 жыл бұрын
I was gonna say, I’m learning this in Level 2 biology here. (I’m 15, in a 16 year old class)
@FishoeShoe_da_great 4 жыл бұрын
"why is a teenage boy similar to helicase? they both want to unzip your genes (grins)" I'm speechless
@JulioFromBoston 5 жыл бұрын
Editing team: "Hank please hold up a shoelace and be amazed by it"
@rishinixon7560 4 жыл бұрын
ha!
@ExplaurenwithLauren 5 жыл бұрын
Good Luck on your test/exam/final/quiz tommorow that we both know you are just now studying for... éxpöšêď ;)
@georgiaalexandriaa 5 жыл бұрын
it's actually today
@kyleharvey3824 5 жыл бұрын
100 percent facts
@EarlyOwOwl 5 жыл бұрын
Thanks fren
@hxhchimeraantarc2268 5 жыл бұрын
Exposed
@jays9572 5 жыл бұрын
i feel very ,much attacked
@YoyoBear12 7 жыл бұрын
Thank you so much for covering Rosalind Franklin, some of my previous instructors only briefly mention her and they rarely discuss her major contributions to the discovery of the DNA structure.
@tankgunner32 8 жыл бұрын
its crazy how a youtube channel that i get for free is a better teacher than the teacher i paid hundreds of dollars for. goddamn the college life.
@ebkdoa3535 6 жыл бұрын
Tell that to the people who will be paying money to watch this in a couple months
@mycaroxas4088 5 жыл бұрын
Paid with ads my friend. and yet, I love Crash Course!!!!
@BannerOfBlasfemy 5 жыл бұрын
college should be free
@bluon259 5 жыл бұрын
BannerOfBlasfemy college is free for me at least, all I had to do was write a paper and take a test. (I’m a freshman in high school). It all depends on where you live and where you look, and whether or not the opportunity is there yet. But yeah, people should go to college for free if they have the drive for it.
@sourcetext 5 жыл бұрын
College is a for profit business. The ancient Greeks called them Sophists
@katiesingsthings6453 8 жыл бұрын
Anyone else cramming the day before the exam?
@mariadedios9081 8 жыл бұрын
+KatieSings&Things ME!
@catherinec3735 8 жыл бұрын
+KatieSings&Things I'm glad im not alone XD
@arwahasnain5624 8 жыл бұрын
This is the time Crash Course's views exponentially increase the most
@darkdestiny3700 8 жыл бұрын
maybe...
@shingaikagunda6426 8 жыл бұрын
Meeeee!!!! Lol
@christinemilling8568 5 жыл бұрын
I started teaching biology in 1993 and I KNOW my kids (now middle aged) KNOW it was Rosalind Franklin who did the work. Hank, thank you. I left teaching, but am thinking about getting back into the classroom. Using your videos to study up for the test to get recertified. :)
@toshido_yamada 5 жыл бұрын
Gl, i hope you get re certified
@purplegypsylady777 4 жыл бұрын
Please.. The world needs good teachers!!
@riyasingh110 6 жыл бұрын
HANK: Hey you wanna make one Subtitles says :oh dear god *Squeak**squeak*
@cyberxxxcyberxxx9464 5 жыл бұрын
I like the adult jokes on this episode😁😅
@katieniwa7961 4 жыл бұрын
I don't understand the joke...
@PersimmonHurmo 4 жыл бұрын
@@katieniwa7961 you're too young, get off the adult internet
@TheHappyHummy 4 жыл бұрын
His name is hank...
@joestar8112 4 жыл бұрын
Oh my oh my
@surajbhat5447 8 жыл бұрын
this 12 minute video basically goes over eveything we've learnt in pre-ap bio's dna unit, which took 2 weeks for us. Thank you Hank
@Epicgamerbro2000 8 жыл бұрын
He explained t better than my lazy ass teaxher
@Angelicmey 8 жыл бұрын
+suraj bhat same
@djmoneystacks3600 8 жыл бұрын
+Dale are you mad😁😁😄
@jeremytownsend6805 8 жыл бұрын
+Dale Some teachers can't have class lectures and this is more interesting than reading a chapter in a textbook.
@wizardvenom8500 8 жыл бұрын
+Dale You can't even speak English lol
@alannar.8701 8 жыл бұрын
Trying not to fail my bio final. This is so helpful, and I want to thank the Green brothers for starting the channel, and the whole CC team for making it a reality. You guys are kind of the best.
@yelectric1893 6 жыл бұрын
Good luck
@beckylieb2637 6 жыл бұрын
awesome idea and dedication indeed... but they have some financing... bet they would be shut down if they taught some of the truth in science and history. ....
@minjeekim3167 4 жыл бұрын
When Hank said "POP QUIZ!" my heart started racing so fast.
@keshiaduplooy119 5 жыл бұрын
The funny part about biology is that everyone pronounces everything differently
@mariakal605 7 жыл бұрын
Usually when I watch videos to catch up on material idk the night before an exam I watch it in 1.5 speed but these crash course videos are the only ones I actually have to watch in like .5 speed omg
@med8615 7 жыл бұрын
working with 2x speed over here, gl.
@jettlaxholly 6 жыл бұрын
mariaarakal lol I’m usually at 1.25 speed with home because he already talks fast, but I have no time to waste
@rachelelizabeth6017 6 жыл бұрын
jett lax same! I always have mine at 1.25 or 1.5 speed! 😄😄😄
@matthewvillalba-mutis6545 7 жыл бұрын
When he said "Pop Quiz", my heart jumped. Sadly, I'm used to my science teacher saying that.
@alicemeliksetian7981 4 жыл бұрын
Matthew Villalba - Mutis thats what happened to me when he said “ *hey, you wanna make one* ”
@Dixie.Normus0811 5 жыл бұрын
Who’s here cramming before a test in 2019 lol
@ryna2502 5 жыл бұрын
y’all doing the AP test?
@aarishhanif1837 5 жыл бұрын
Yep
@daciannabel9076 5 жыл бұрын
Me😂
@dearielbell663 5 жыл бұрын
Me I have the biology staar tomorrow 😔😭
@gomamon15 5 жыл бұрын
Me right now for a final. Not that i wanted to cram but I have job and other classes, so here i am... tons of luck everyone
@fredericavonsiemens6956 4 жыл бұрын
anyone find it weird to think about how when this video was first released it probably got like 20,000 views but then over so many years millions of students watched it
@missfluffybuns7759 8 жыл бұрын
Kudos for giving Rosalind Franklin the credit she deserves!
@laurasutherland2352 6 жыл бұрын
Kinda bothered me that he didn't mention that women scientists tend to be disregarded for the sole fact of their being female. Still, love me some Hank Green.
@pastsubstance2930 6 жыл бұрын
It's pretty sad that that is a controversial topic to even discuss about.
@victorfergn 6 жыл бұрын
hmm the info is wrong, it wasn't Franklin who shared the info (she didn't like sharing anything, she even disliked when other people got into her lab) the one who shared the info was Wilkins, he showed the picture of the double helix to Watson; Franklin got furious about that (Wilkins and Franklin hated each other) Besides... she was far from theorizing how DNA worked, it was Watson how figured it out. Obviously Franklin had a key role but she wasn't Emmy Noether.
@pastsubstance2930 5 жыл бұрын
Just another Bird no not everyone. Probably the people you know and where you come from highlights Rosalind’s scientific feat but not every country.
@seamusmcc5 9 жыл бұрын
During the diagram from 3:00 to 3:40 all of the carbons that you circle and label are 5' carbons. The 3' carbon is the carbon that the phosphate group bonds to on the next nucleotide. So on the left stand the 3' carbon of the bottom sugar would be the very bottom left carbon with the two atoms (hydroxyl group) hanging off of it, and the corresponding carbon in each subsequent sugar.
@laurenwallace8204 5 жыл бұрын
I don't remember Crash Course being this complicated when I was in 9th grade biology, though I guess I should be thankful that 6 years later it is still helpful for my college level genetics class.
@melaniec9079 5 жыл бұрын
I love how the captions say "Hank why" when he told the helicase joke.
@Kpoper4life 9 жыл бұрын
"How is a teenage boy like the enzyme Helicase? They both want to unzip your genes" Oh boy...
@ThingsUShouldLike 6 жыл бұрын
My teacher showed this video in class and literally muted that part 😂😂😂 I got curious to what he said so I’m here now...
@stefanli1755 5 жыл бұрын
YEESSSSSS!!!!!
@kikialeaki1850 5 жыл бұрын
Oh helicase
@xxdavexx23 9 жыл бұрын
I'm glad he included that Rosalind Franklin contributed to the findings of the DNA structure not until this year after my bio teacher told us about Rosalind Franklin have i found out that it wasn't all just Watson and Crick. I have lost lots of respect for Watson and Crick after that day.
@Wolfeywolf16 9 жыл бұрын
It angers me to see how discredited she was
@ohkaryukai 9 жыл бұрын
Taylor Clay they literally stole her work. you'd be surprised at how often men are credited for things women did. Ava Lovelace, Sanora Babb, Lise Meitner, Cecilia Payne, Hedy Lamarr, Vera Rubin. It's pretty awful.
@nexusmares3371 9 жыл бұрын
harumi Well let's not get carried away. "You'd be surprised at how often men are credited for things women did." Making statements like that perpetuate sexism. It's not like men everywhere have declared war on women and are out to steal their work. What if Watson and Crick had been women? It should stay a "x" stole from "y" issue, which is what it really is, not a man stole from woman issue.
@ohkaryukai 9 жыл бұрын
Ella Blun preach.
@ohkaryukai 9 жыл бұрын
Vinicius Fernades i suggest reading a few of her biographies if you'd like to learn more =) she was pretty rad in real life.
@xenaval 5 жыл бұрын
my science teacher played this in class and when it got to the joke omg I'm screaming
@monicavega-hernandez8787 5 жыл бұрын
minute 3:07-3:42 has an error. The 5' is correctly highlighted but the 3 ' is wrongly highlighted.
@ryankruskamp8973 5 жыл бұрын
Thank you! It wasn't making sense so I checked the comments to make sure.
@hifrax 5 жыл бұрын
and i think the 10:57 part has an error as well. doesn't the lagging strand go in 5'-3' direction?
@Jaspertt1 4 жыл бұрын
@@hifrax yeah i think so as well. I think what they meant is that the lagging strand goes into the 5'-3' direction which would mean the DNA polymerase won't work 'efficienly' since it cannot go in the opposite 3'-5' direction
@abdallab8511 4 жыл бұрын
Yess i am checking the comments to make sure
@gretchendean7346 4 жыл бұрын
@@ryankruskamp8973 great that folks who caught that commented. Comments RULE!
@luigisim3 9 жыл бұрын
"Hey... you wanna make one?" -Hank, 2012
@sarah45532 9 жыл бұрын
I laughed so hard xD
@hi-lo1jm 7 жыл бұрын
"(oh dear god)" -The subtitles, 2012
@anjalimishra6470 7 жыл бұрын
[when talking about teenage boys and helices both unzipping genes] Hank why- The subtitles
@evyuwu4509 6 жыл бұрын
PlatinumLuxray freaking creepy, we’re currently watching this is science class.
@alhassan5623 8 жыл бұрын
I wish he is my anatomy teacher, I would get A so easily. my anatomy final is tomorrow and your videos help me in not wanting to read half a textbook
@KitKatKool99 8 жыл бұрын
SamE AND I SEE CHANYEOL
@alhassan5623 8 жыл бұрын
+Zsófi Szabó I passed my test yay!!! I can watch exo videos all now
@humixmusic4lyf 8 жыл бұрын
+pcy_exo2 congrats! ^u^
@alhassan5623 8 жыл бұрын
+humixmusic4lyf thank u!!^^
@whenidieburymewithapenguin3136 8 жыл бұрын
I see my bias in you profile pic :3 Congrats on passing btw X"D
@jaredschnellbacher3204 5 жыл бұрын
5:28 "See how that works? It's not super complicated" yEaH oKaY
@coconutsharksinthewater4728 4 жыл бұрын
same i didn't get it at all xD
@jaydenjiang2767 8 ай бұрын
I love Hank Green, his videos are so funny. I honestly don't care what he talking about, it is just sooooooooooo interesting.
@MangaEater68 10 жыл бұрын
Thank you for translating my textbook into understandable English terms. I love you
@JackT13 8 жыл бұрын
Oh behalf of my dog who just watched this, he says he 'is most certainly not a human and did not care for the accusation'. I'm afraid he has unsubscribed
@LuisSierra42 8 жыл бұрын
My cat had a similar reaction
@shyamalsingaravelu92 8 жыл бұрын
tell your dog hes taken drugs to be able to even understand this
@JackT13 8 жыл бұрын
Shyamal Singaravelu he just said 'ketamine is a wonderful thing'
@johnbradford6875 8 жыл бұрын
I was put on ketamine after a had several surgeries within a month (they were worried about the amount of opioids I had been on, and the amount needed to control pain straight after surgery having a shoulder replacement might kill me post-op). I beseech the medico's out there, be it G.Ps, surgeon, nurses etc, to give patients the heads up about ketamine BEFORE the surgery - I came out of surgery, woke in the recovery room, and thought I was in a cartoon - everyone looked like something between a Disney character and Avataar (did I spell that right?). I would have panicked, except I was too smashed. I asked if I was hallucinating, and some guy I assume to be the anaesthetist said "no," that's the ketamine," - if this wasn't hallucinating, I need a new definition. I was in a lot of pain, but it was someone else's pain, if that makes sense (if you were on ketamine it might - it's called a "dissociative state", IMT). Very trippy. Wonder if animals have this happen?
@JackT13 8 жыл бұрын
+John Bradford you are a cartoon. Or at least your user icon suggests such
@batumanav 4 жыл бұрын
I found myself in here when I feel hard to understand a subject in biology. Than, BOOM. It feels helixciting.
@HomicideHeather 6 жыл бұрын
For the first time in my two years in college, I actually understand what I am seeing. Thank you. I am in the MLT program trying to understand how PCR testing works but in order to do that I realized that I REALLY need to comprehend DNA and how it is made in order to understand how it is taken apart and analyzed. You have really given me a strong visual and I can't thank you enough.
@JKay5phD 8 жыл бұрын
Good luck tomorrow everyone!
@jennanicole6354 5 жыл бұрын
JKay5phD exposed
@AndrejNikolov-xw2gi 5 жыл бұрын
Thanks man! :)
@l3mi11ion 5 жыл бұрын
JKay5phD thanks bro!
@VikasYadav-to1xr 5 жыл бұрын
Thanks:)
@ainsley5563 5 жыл бұрын
lmaooo
@NoyumiAo 9 жыл бұрын
Was having trouble remembering all the steps of the lagging strand but now remembering it for being a scumbag strand makes it so much easier
@rafaelcontreras4358 5 жыл бұрын
Jiji meAmeliacontreras
@rafaelcontreras4358 5 жыл бұрын
Creo ieuyfieyeutdy
@whiteeyedshadow8423 4 жыл бұрын
"hey, you wanna make one?(oh dear god)" lol
@HiroDoodlez 6 ай бұрын
Shoutout to Hank for teaching me before my biology test IN LITERALLY 5 HOURS
@gregjang5402 9 жыл бұрын
"Hey. You wanna make one?" I'm eleven.... My god....
@arabeasy 9 жыл бұрын
Lololololololololololollolololololoollolllloolol
@TheSpicySimon 9 жыл бұрын
"Hey, you wanna make one?" "Im a guy." "My god"
@gregjang5402 9 жыл бұрын
So am I.
@rexyboi466 9 жыл бұрын
So am i
@gregjang5402 9 жыл бұрын
School homework.
@sidsin7538 10 жыл бұрын
Crash Course is one of the best things to be on youtube, its fun to watch educational and overall helpful. You guys have proven that knowledge is power in so many ways, breaking down complex subjects while maintaining a high energy level teaching process which does not leave a student sleeping. You guys are like the Bill Nye of our time, keep up the good work. Its really pathetic that more people don't know about your work, grade schools should promote your program, but then again they are more focused on their sports teams, but overall for all of us non-athletic people you guys are champs.
@bbqyee7350 5 жыл бұрын
Who is watching this before the AP Biology test? Mine is next Monday fml
@ChiNguyen-mp5kd 5 жыл бұрын
Haha me too but im happy with an 1 😂
@carlie3628 5 жыл бұрын
Same
@anselcheesecake419 5 жыл бұрын
@@carlie3628 same
@giannagowe8486 5 жыл бұрын
My cape Unit 1 is tomorrow
@realgrieve 4 жыл бұрын
Yuh bug mine is first day of school
@skylerparadise2 Жыл бұрын
Hank. You are a blessing to every student in the world. Reading and digesting a convoluted and confusing textbook is so much easier after getting a grasp on the general idea first from watching these videos. Thank you so much!
@kayeamele 8 жыл бұрын
Keys to being successful as a Pre-Med major: 1) Procrastinate all semester 2) DON'T read any of the assigned material 3) Watch every CrashCourse video the night before an exam 4) Walk into class confidently knowing that you prepared well for the exam
@sumiatheangel9397 8 жыл бұрын
+kayeamele step 5: panic as you forget half the names of the muscles and bones you supposedly learned the previous year.
@Jnniesx 9 жыл бұрын
phrase the lord for youtube teachers. Why waste your time reading long ass textbooks and still end up confused when you can just watch a bunch of these videos. These are so much cooler and so much less boring
@bananimal45 9 жыл бұрын
"the lord is...uh...the lord." ...ohhhhh you meant PRAISE the lord.
@fmar105 9 жыл бұрын
Jennifer Li I disagree. A textbook will give you a much more in-depth view of such mechanisms than a ten minute video, and will leave you with a much better understanding. I find my textbook challenging and interesting. These videos are great, but they are mere supplements to textbooks and the like.
@ryrden927 6 жыл бұрын
To Hank and everyone at Crash Course who helps in creating these videos. I just want to thank you so much on behalf of all of the panicking people who have trouble remembering all of this information. These videos are absolutely incredible! Keep doing what you're doing! :)
@laurenmcshane4628 6 жыл бұрын
Although I only watched half of it and only understood a few parts, the laying out of it combined with my other revision resources finally helped me get the gist of it - you are a star, thank you!
@marianascimento1498 8 жыл бұрын
On 3:35 there's a mistake in the sketch. The 3' carbon is indicated on the 5' carbon, instead of the 3'
@esmeraldacuriel4618 8 жыл бұрын
+Maria Nascimento yes i was so confused about that
@natattacc99 8 жыл бұрын
So...which side is 5' and which side is 3'?
@coenijn 8 жыл бұрын
+NH.-B Well the 5'-prime end was shown correctly both times, the 3'-prime end however is located at the third C-atom. In the video both the 5'-end and the 3'-end are indicated at the 5'-end. If you take the left strand (the side of the purple ribbon) of nucleotides you'll find that the 3'-end of deoxyribose is located at the lower left corner of said molecule. Since the saccharides are shown in a Haworth projection it's quite difficult to point out. Here's a not very good Fischer projection of deoxyribose I made pointing it out. Remember, this is the same molecule as shown in the clip, just a different style of drawing it. HOC-CH2-CHOH(this C-atom is the 3'-end)-CHOH-CH2OH(and this is the 5'-end). In an aqueous solution (almost) all monosaccharides (such as deoxyribose) will form to become a circular structure, such as shown in the video.
@nureileendeannakamaruizam3961 8 жыл бұрын
+NH.-B bealbio.wikispaces.com/file/view/dsDNA.jpg/166732981/350x272/dsDNA.jpg
@natattacc99 8 жыл бұрын
+nureileen deanna kamaruizam Thanks :)
@oayabacnhoj6855 10 жыл бұрын
I cried about how informational this is.
@vladislavapetrova5983 7 ай бұрын
Their videos have come so far since 2012, from the content to the animation graphics, looking back he is so young and derpy! And here we are, 11 years later he is still saving my butt, from highschool all the way to finishing college. Thank you Hank Green and the team, for helping us get through school in a fun and enjoyable way!
@himanshugupta1566 4 жыл бұрын
Thank you so much crash course...you guys are lifesavers and explain so much from scratch in such less time...love the animation. Pl keep helping us never stop creating
@simbananza 8 жыл бұрын
does anyone else find it creepy that this happens in ur eyes. like its happening right now and you dont see it.
@jonathanmusemeche4865 8 жыл бұрын
+blo shit up Your pupil is just open space covered by the cornea, a multicellular tissue that contains no blood vessels, that's why you don't see it occurring. The nerves behind it detect light and then your brain makes sense of those indications. Not to mention that cells are microscopic and the nucleus is inside of the cell and chromosomes are inside of the nuclear membrane of the nucleus and so on... So then you might ask well how do those cells stay alive without oxygen? Because all eukaryotic animal cells need oxygen for respiration to utilize energy and there are no blood vessels to provide the oxygen. The cornea diffuses oxygen from the tears secreted by your tear ducts.
@reshmi5333 8 жыл бұрын
+blo shit up hi !! fellow kpopper !! nice to meet a kpopper here
@Simplebeez 8 жыл бұрын
+blo shit up High Skool!
@satan4606 8 жыл бұрын
i see it
@squiddi1393 8 жыл бұрын
+blo shit up You're totally incorrect. First off, the cells in your eye don't actively divide. They are with you your whole life. They are constantly in the G0 phase therefore DNA replication doesn't occur in them and so you wouldn't see this anyways. Replication only happens in preparation for mitosis in interphase, like when you grow as a child or your cells divide and repair your body when you get a cut on your skin, otherwise cells refrain from dividing hence they don't replicate DNA.
@Dstewar25 8 жыл бұрын
my teacher skipped the part where he joked about unzipping jeans so I looked this up to fond out why XD
@wizardvenom8500 8 жыл бұрын
+Darby Jones seriously? haha. What year group are you in? It's hardly inappropriate lol
@Dstewar25 8 жыл бұрын
9th and I know right lol.
@adriennebatty3787 8 жыл бұрын
+Darby Jones Oh my gosh we were learning about this and I'm in an online school so I typed out the joke in the class and my teacher did NOT like it.....it was very awkward for me. I would have died if I was in an actual physical school. But we're in 10th grade, it's not that bad of a joke.
@inserthere7048 8 жыл бұрын
+Techman shit hide your meth the apocalypse is coming.....like me ;)
@tiglathpilesariii 8 жыл бұрын
+Darby Jones Me too xD
@Mohamed-jv6nv 5 жыл бұрын
Just think how far CrashCourse has come now! Thank you CC and Green brothers for helping me get through my exams
@nativaconcepcion879 5 жыл бұрын
This is SO good for studying for the TEAS exam. It’s quick n he touches on all the important factors of dna while being a lil nerdy funny..🙏🏽
@ageovlove 8 жыл бұрын
This video was perfect for helping me procrastinate on studying for my biology exam. Thanks Hank!
@ARedVelvetBunnie 7 жыл бұрын
HOLD ON A SEC 'WANNA MAKE ONE'?????
@theultimatedoom6896 7 жыл бұрын
Make a DNA model xD
@ARedVelvetBunnie 7 жыл бұрын
lmao I got that in a wrong way
@vanessanelson9330 7 жыл бұрын
lol put on captions/subtitles "( oh dear god)"
@mahdiyadegari8282 7 жыл бұрын
Oh dear
@kingbartholomewthe1above317 7 жыл бұрын
about to type that
@yijieguo5908 4 жыл бұрын
I remember watching this video for exams in middle school and high school. Now I'm in college, and I'm here once again :(
@palmalorenzo7778 4 жыл бұрын
this guy has brought me though all my school years, i cannot thank him enough!!
@kieran2blest 8 жыл бұрын
these videos are the best. the editing and detailed number spewing gives us a few specifics we may have missed in individual studies. this "speccy-eyed nerd" has helped a lot of people understand a number of different topics (and has definitely helped me pass a few challenging classes)by showing off his big brains on the internet by describing whatever topic he is needed to, and people like it so they donate and subscribe to his channel at their leisure
@weiurdgurl 8 жыл бұрын
The joke Hank makes in the video at 9:25 made me laugh so hard.
@weiurdgurl 8 жыл бұрын
+Sushil Mario You know how in the DNA replication process the double helix has to unzip. Boys would like to do the same thing with a girls jeans. But sorry that I killed the joke.
@weiurdgurl 8 жыл бұрын
+Sushil Mario 👍👍👌😆😆
@isaacmathews4693 8 жыл бұрын
9:22 Lol! :)
@JokerMr13 5 жыл бұрын
These are fantastic. Thank you for the uploads! I hope you guys bring back more science episodes
@vilunar5813 4 жыл бұрын
This video was really helpful for me to comprehend DNA and its replication process. I will dare to say that it is the best video I have ever watched about this context on KZfaq. Thank you!
@laurenf.7922 8 жыл бұрын
This really helped me as I have the EOC in a day!
@ellensmith8089 9 жыл бұрын
"How is a teenage boy like the enzyme helicase? They both wanna unzip your genes" oh my lord i have not stopped laughing
@javierayala1648 4 жыл бұрын
years of trying to understand this from many different professors broken down into only 12 minutes brilliant.
@timv6141 5 жыл бұрын
Watching this again. Hank is a great teacher! Thanks for everyone who helped make this
@RickReinster 10 жыл бұрын
I start watching this so I understand my class better, and I end up realizing it's happening ALL THE TIME in my body, so cool!
@theresepabroa4389 7 жыл бұрын
I love this channel! Thank you for all of your videos! You've helped out so many students!
@AL3X042399 6 жыл бұрын
This cleared up the lagging strand confusion I had and I'm so thankful for this video now.
@DexterWolf-ds7nz 4 ай бұрын
9:25 nahhh bro Hank is wild sometimes😭
@nobeladhikari6602 7 жыл бұрын
i have never understood the 5 prime 3 prime thing...,and probably never will.
@Androctonus84 7 жыл бұрын
This video won't help with that, since they circled only the 5' carbon on each sugar, but labelled half of them 3'.
@conceptswithkat3045 7 жыл бұрын
Well if it helps, nucleotides are added to the 3' end because it has a free OH group which reacts to form the bond, so they're being added from the 5' to the 3' direction
@georgiamitchell3692 7 жыл бұрын
No one understands, not really.
@dhruboriley2931 7 жыл бұрын
Its chemistry :'3
@abigailh7223 7 жыл бұрын
Look "5 prime and 3 prime DNA diagram" up on google images. Look at a diagram of a single piece of DNA (as in, not the chain, but one rung of the ladder, made of three parts). It should show that the "top" of each DNA rung (at top of phosphate) as "5 prime", and the "bottom" of each rung (at bottom of sugar) as "3 prime". Therefore, as they chain together, you'll have one side of the DNA helix ladder with all the 5 primes facing up, and the other side of the DNA ladder helix with all the 5 primes pointing down. (and yes, he mislabeled the 3 prime and 5 prime in the video). (Why are these parts of the DNA called 5 prime vs. 3 prime? It has to do with the naming of the Carbons in the carbon rings involved. See W douglas Driver's comment somewhere else under all these replies to NOBEL ADHIKARI for a good explanation...)
@ramanabalachandhran 7 жыл бұрын
This is fabulous, awesome, laudable, appreciable, super-helpful, fantastic stuff. Hats-off to the Crash Course™ team! and....... the way Hank introduces or sticks in humor in between is just too funny! Thanks a ton, Ramana
@elisemahar2395 4 жыл бұрын
luv this dude. couldnt pass my tests without him. he has the only non-boring vids
@alexandervidal7242 5 жыл бұрын
Got an 83 on my Biology exam :D goodluck to ya!!
@TheHappyHummy 4 жыл бұрын
You suck I got a 100
@aimee-hyj 4 жыл бұрын
@@TheHappyHummy higher marks doesn't equal a better person, clearly
@nathanhe4214 4 жыл бұрын
@@aimee-hyj lmaooo preech
@emmasabat5926 4 жыл бұрын
@@TheHappyHummy Two can play this game. I got a 112 on my last bio exam.
@ChiaraCami 10 жыл бұрын
The freaking jingle. One of the 1874959 reason why I love crashcourse
@veronicabursek-krekling6349 8 жыл бұрын
I have a Bio test tomorrow and I'm so confused but this video helped so much!
@killyourbunny 8 жыл бұрын
+Veronica Bursek-Krekling wow you must be so smart
@veronicabursek-krekling6349 8 жыл бұрын
+MeepMeepTheMemeCreepBeepBeep I'm sorry, what is that supposed to mean?
@killyourbunny 8 жыл бұрын
Veronica Bursek-Krekling you dont know what smart means?
@veronicabursek-krekling6349 8 жыл бұрын
I can promise you that's not it, bye
@killyourbunny 8 жыл бұрын
+Veronica Bursek-Krekling what?
@Sam-vs6rg 4 жыл бұрын
0:45 turn on subtitles, will not disappoint you I swear
@firefly-fez 5 жыл бұрын
Props to whoever did the subtitles for this episode, they're hilarious! 😂🤣
@MrMasterDebate 10 жыл бұрын
..this channel is the ONLY reason why im getting a good grade in my science class
@KenseiSensei 8 жыл бұрын
When he said "hey you wanna make one" I'm like Hell naw to the naw naw naw
@BigBoss-sm9xj 8 жыл бұрын
Where is kirito!!! Sinon!
@KenseiSensei 8 жыл бұрын
+FOX HOUND HE BE CHEATIN ON ME FUCKIN 192839 BITCHES
@BigBoss-sm9xj 8 жыл бұрын
Lol XD
@jinnyjinjin 8 жыл бұрын
+Otaku Sensei??? I'm always open ( ͡° ͜ʖ ͡°) You can be my bitch
@owenwilliams9137 8 жыл бұрын
+FOX HOUND OH WOW. really. your on revision video and this is what your attention is on. (not dissing sword art online)
@jordan-qr1js 4 жыл бұрын
thanks hank, you did a better job at explaining this in 10 minutes than my biology teacher in 2 weeks :)
@alexandercasuga3989 6 жыл бұрын
I love your lectures. It's not boring. Thank you for sharing your knowledge.
@stoicfloor 10 жыл бұрын
Everyone who studies Biology should watch this.
@dolphingirl1205 10 жыл бұрын
That helicase joke omfg
@Imogene512 10 жыл бұрын
I will never forget what helicase means now haha!
@oliverskoglie2804 5 жыл бұрын
I'm currently studying Biosciences at uni, and I it made me so extremely happy to see that my lecturer had linked this video on our website, for us to watch!!
@Thatearthychicc 6 жыл бұрын
I’ve been watching this guy in all my 3 years in college. All my prereq classes for nursing school are of course science-based & this guy has a video on everything I swear!!! He is so smart
@KikoJimenezElPistolero 8 жыл бұрын
I swear this human body of ours is so beautifully made in puts machines to shame
@poisonousdurian3689 6 жыл бұрын
It*
@ZeeGhost713 5 жыл бұрын
@@poisonousdurian3689 It*
@bradynichols5380 5 жыл бұрын
@Zbot It*
@Alena8181snookie 5 жыл бұрын
Brady Nichols It*
@oren5332 5 жыл бұрын
Agreed but why so complex I don’t understand anything being taught
@EdilsonJacobSilvaJuniores 9 жыл бұрын
Wow. I thought these videos were good only for high school, but I just noticed you pretty much summed up my first 4-hour Molecular Biology class.
@courtneyprather5111 6 жыл бұрын
These videos are so helpful! Much easier to understand than reading a textbook. Thank you!!
@under_the_night_sky5380 4 жыл бұрын
I learned more here in one video than I did from 5 science sessions. Props to you.
@alleghenymusicacademy 8 жыл бұрын
When my baby is fussy, putting him in front of your crash course videos calms him.
@catholonelbridget1072 8 жыл бұрын
This is parenting people. Parenting in its finest.
@Awgez24 8 жыл бұрын
Give child minecraft to pacify it. Child pacified for the next two decades.
@coreenthusiast 5 жыл бұрын
Your baby is a nerd
@theghostofspookwagen4715 9 жыл бұрын
Only a very small number of people here will understand this, but... The way I remember what Okazaki fragments are is this--the two strands are only gonna be together a short time before they're separated permanently.
@totheblueberry 9 жыл бұрын
AHHHH! THE FEELS! THE FEELS! I was actually going to make a comment about Okazaki hahaha
@theghostofspookwagen4715 9 жыл бұрын
Glad to be of service.
@totheblueberry 9 жыл бұрын
Ahh, stop it! I'm gonna start crying when I'm taking my Bio Exam tomorrow! :O
@iloveu975 9 жыл бұрын
I don't get it! Please let me in on the joke lol
@theghostofspookwagen4715 9 жыл бұрын
It should be noted that, in a similar fashion, both of the Okazakis who discovered those fragments suffered a similar fate. However, it was the husband who died and not the wife, and he died of a disease.
@rawanmohammad3356 4 жыл бұрын
Watching in 2019, I LOVE CRASH COURSE
@chium1731 6 жыл бұрын
"it's double helix-citing" i love these dorky puns
@loganfuchs7773 7 жыл бұрын
You did these years ago but, thank you. I had a horrible high school edu. so I'm trying to catch up and this is helping me understand so much more than just reading. TLDR: I'm dumm. you make it easier to be smart
@jesseclark7105 8 жыл бұрын
The guy who covered this in class went through 47 slides in (I kid you not) 20 minutes. I learned more in the first minute and a half of this than I did for the entire lecture.
@kasigraham2283 6 жыл бұрын
Jesse Clark my anatomy professor last semester went over entire chapters in one class. Entire chapters could consist of every bone in the body, organ systems, cell structure/reproduction/transcription, and would go down into molecular detail. AND HE EXPECTED US TO ALL HAVE EVERY BIT OF IT MEMORIZED IN A THREE DAY PERIOD. Needless to say, 80% of the class failed.
@metronini 5 жыл бұрын
Hank Green: "Hey, wanna make one" Me "Ok, I'm out!"
@JohnnyWalkerBlack142 5 жыл бұрын
Thank you for this video so much! I was having so much trouble understanding replication of the lagging strand, but now that I watched this video I understand everything. Out of every video I watched on replication, this video explains it the best.
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