Doctor explains C-peptide blood test used in diabetes

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Күн бұрын

In this video Doctor O'Donovan explains the C-peptide blood test including 1. What C-peptide is 2. Why the test is used 3. What the result of the test might mean.
C-peptide can be useful as a marker of insulin production.
High concentrations of C-peptide within the bloodstream generally indicate high concentrations of insulin. This may be due to excessive insulin production by the body or insulin resistance. High concentrations of C-peptide also are seen with insulinomas which is a tumour of the pancreas that causes excess insulin to be produced. It can also be seen in other disorders such as hypokalaemia, pregnancy, Cushing's syndrome, and kidney disease.
Low concentrations of C-peptide are seen when insufficient insulin is being produced by the beta cells or when production is suppressed by injected insulin.
More information on diabetes: www.nhs.uk/conditions/diabetes/
More information on C-peptide: labtestsonline.org.uk/tests/c...
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The video is intended as an educational resource only. The information within this video or on this channel isn't designed to replace professional input, so if you have any medical issues please consult a medical provider. No professional relationship is being created by watching this video. Dr. O’Donovan cannot give any individual medical advice. All information should be verified for accuracy by the individual user. Dr O’Donovan accepts no responsibility for individual interpretation of data, although it is always accurate to the best of his knowledge at the time of the video being published. This is an EDUCATIONAL video. Images are used in accordance with fair use guidelines.
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Пікірлер: 84

@candycox9601 Жыл бұрын

Excellent description

@rs-cw7bd Жыл бұрын

Thanks for your very clear explanation!

@DoctorODonovan Жыл бұрын

No problem at all! Thanks for watching

@Unknownfisherman Ай бұрын

Great video. Thanks

@DoctorODonovan Ай бұрын

Glad you liked it!

@mariemac5347 Жыл бұрын

Really helpful! Thanks

@DoctorODonovan Жыл бұрын

Glad it was helpful!

@antoniocognato5023 9 ай бұрын

If I fasted for 2 days for the blood test, can that make a difference? Mine was low . But like a half a point below the low mark

@elsahernandez7257 3 ай бұрын

My c peptide is .9. On the low end. A1c 5.9 and going up. I exercise, eat low carb, low sugar. But can’t seem to get below 130s on fasting glucose. Night glucose all day.

@dr.abunasermuhammadkibriya7320 Жыл бұрын

Thanks!

@DoctorODonovan Жыл бұрын

No problem!

@Dr.ShashikantJ 10 ай бұрын

Thank you for this information.. But I hav question.. If Serum Insulin (fasting or PP).. test is already available to assess the insulin levels in blood.... Whts the significance of C- peptide test ..in the assessment of Insulin? Thank you

@bradfry2259 Жыл бұрын

I've just been just this week diagnosed with diabetes and they are suspecting some form of type 1, they requested a c peptide test apparently to see if I'm making any of my own insulin. I'm already on insulin so not sure if that effects the test.

@martarico186 3 ай бұрын

What are normal levels oc cpeptide

@9035137984 Жыл бұрын

Hi doctor Please clear me about this In Insulin resistance as glucose metabolism is improper so insulin production is more?? Is it so?

@robsweatherchannel 10 ай бұрын

My insulin is 441 and my c-peptide is 6.8 qll very high apparently but my glucose can be low bur usually OK is this of concern my ASO is 520 level too an infection presence it seems what to do tried my GP not helping for some reason

@mansooralikhan8303 Ай бұрын

Sir can C-peptide indicates insulin resistance or one should go for HOMA IR to check it?

@Melanie-gu4cl 7 ай бұрын

Hi Dr. O'Donovan. I have Diabetes- Type 2, but I'm "underweight". I saw a video from someone else saying that you can use the C-Peptide to find out if you have been "misdiagnosed" as having the wrong type of diabetes. Is that true? Thanks,

@aaziz41 Жыл бұрын

Great info, better test values would have been discussed for better understanding

@DoctorODonovan Жыл бұрын

Thanks - it’s a bit hard as different labs have different values

@DoctorODonovan Жыл бұрын

Thanks - it’s a bit hard as different labs have different values

@leimat86 Жыл бұрын

Hi. Does c-peptide always decline for type 2 diabetics over time and if so around how many years after diagnosis? Thanks!

@jdtown6585 10 ай бұрын

Yes. I finally had to start insulin injections after about 10 years after my diagnosis.

@9929kingfish Жыл бұрын

I wish I knew what my C-peptide was before when I was prediabetic. I went low carb and reversed my pre diabetes. C-peptide was 1.5 after going low carb. I'm sure it was about 4 when my A1c was in the prediabetic range of 5.7.

@towkircontent Жыл бұрын

after reversing the pre-diabetic, what's now your c peptide? does it increase?

@evramirez87 Жыл бұрын

Hello, do you know how to read the results? I just obainted them, and they say I have 0,829 ng/ml. I am 35 years old. Thanks in advance

@jdtown6585 10 ай бұрын

1.5 is still on the low end of insulin production. My thought is you'll be insulin dependent within a few years.

@jdtown6585 10 ай бұрын

@@evramirez87 That's barley above the lower level of insulin production. It's where I was before I finally started insulin. While I hated having to start doing injections, I'll gladly keep doing it bc it makes me feel so much better.

@9929kingfish 10 ай бұрын

@@jdtown6585 nah. It’s good to keep insulin low to increase insulin sensitivity.

@sarahhendricks9757 8 ай бұрын

Hi there, I know C peptide should be drawn when the BG is within a normal range in order for it to be accurate. Do you know for how long? Like could it be drawn with the first normal BG? Thanks!

@DoctorODonovan 8 ай бұрын

I’m sorry this out of the scope of my knowledge. Apologies

@Claire-mv1tf 6 сағат бұрын

How is the test done.. My diabetic nurse said it was the fasting finger prick ....and one 2 hrs after food.. I have a feeling this isn't right..

@meghadevadas Жыл бұрын

Sir high c peptide seen in type 2DM and low c peptide in type 1DM .is it like that?

@jdtown6585 10 ай бұрын

Yes, most of the time.

@mohammadtasaddiq2192 Жыл бұрын

Is c peptide levels are diagnostic of type 2 diabetes

@serenityofmind4383 Жыл бұрын

so what is the normal range of c-peptide?

@DoctorODonovan Жыл бұрын

It depends on the lab. www.ucsfhealth.org/medical-tests/insulin-c-peptide-test

@bobshaw8558 Жыл бұрын

Thank you, does the "C" stand for Collagen? I've been taking 3 G of collagen a da for 5 months as a diabetic with cinnamon chromium vitamins b1 ,6 ,12 omega 3 6 9 E should i grt a C Peptides test?

@Mr-hn2bp Ай бұрын

@stoneycraver7249 Жыл бұрын

I was diagnosed type 1 in may of 2018. I was dka when diagnosed, but I have had normal c-peptide levels almost the whole time. I didn’t at first for about 6 months but I surrendered this to God and from that moment they have been in normal ranges. Any ideas on this normal c-peptide numbers for practically 5 years now?

@jdtown6585 10 ай бұрын

I just watched my good friend die from cancer after a stage 4 lung cancer diagnosis in which he swore his christian god was going to save him. 18 months later, during which he just deteriorated to a horrible condition, he went to sleep and never woke. So god saved you but lets countless innocent children die ever day around the world? You're not that special, my friend. You're just lucky.

@brendaandrandyking4126 Жыл бұрын

Hello....so what does a score of 2.8 mean???

@DoctorODonovan Жыл бұрын

"When your results fall below 10 mg/L, you no longer have clinically active inflammation." SOURCE: labtestsonline.org.uk/tests/c-reactive-protein-crp

@paulamorales4234 Жыл бұрын

Hi! Thanks for your education, I asked my doctor about this test and my insulin is 426, what kind of medication should I take? Thanks

@DoctorODonovan Жыл бұрын

Hi Paula. I am sorry but for medico-legal and ethical reasons I can't give clinical advice or pass comment on individual blood results on this channel. This is designed as a general education channel. Please consult your doctor or health provider for individual questions or if you have concerns about your health or blood results who will be able to interpret them in relation to your individual clinical picture. I hope you found the video an informative education resource nontheless. Best wishes.

@paulamorales4234 Жыл бұрын

@@DoctorODonovan thanks, Dr. Donovan, I was never told by any doctor about this test or never they did it. I know now more about because of you, thanks and good day!

@mudslinger888 Жыл бұрын

Meds also called food is all you need, go full carnivore and drop it like a rock

@paulamorales4234 Жыл бұрын

@@mudslinger888 thanks, I believe you and you know they sell insulin capsules. Good day to U!

@miltonkiskumajhi2394 Жыл бұрын

How can I contact you doctor I have some doubt

@DoctorODonovan Жыл бұрын

I am sorry but for medico-legal and ethical reasons I can't give clinical advice on this channel. This is designed as a general education channel. Please consult your doctor or health provider for individual questions. I hope you found the video informative nontheless. Best wishes.

@SamuelOdogwu-ry2en 3 ай бұрын

Writing peptide is it a enough for the doctor to identify?

@SamuelOdogwu-ry2en 3 ай бұрын

The kind of test

@StarvingMyselfToLIFE Жыл бұрын

Are both HOMA IR and C Peptide tests necessary if one is just doing an audit one's metabolic HEALth?

@DoctorODonovan Жыл бұрын

I am sorry but for medico-legal and ethical reasons I can't give individual clinical advice on this channel. This is designed as a general education channel. Please consult your doctor or health provider for individual questions and concerns. I hope you found the video informative nontheless. Best wishes.

@StarvingMyselfToLIFE Жыл бұрын

Cool. Thanks.😀

@jitchem757 Жыл бұрын

Doc how to reach you via email for a review of my c pep of 343pmol insulin 15.8 pmol / glucose is 4.1mmol

@kathydonohoo1180 Жыл бұрын

After I listened to your video, I had a C-Peptide test done. The results were 3.5. Is that a good reading or should it be less? I have been diagnosed as IR and a pre-diabetic. A1C is 6.0

@DoctorODonovan Жыл бұрын

It would depend on local lab ranges. In the UK typical normal range for fasting blood C-peptide levels is around 0.8 - 3.85 ng/mL but ranges can vary between laboratories.

@9929kingfish Жыл бұрын

Continue to lower your carb intake and do intermittent fasting. You will normalize quickly. That is exactly what I did.

@Acts-1322 Жыл бұрын

@@9929kingfishbut keeping some carbs so you keep metabolic flexibility. All carbs are not the enemy, just like all fats are not. Just eat real food as mother nature gives it, not like machines grind it and glue it back together

@jdtown6585 10 ай бұрын

You're lucky to still be producing a boat load of your own insulin. Now is the time to go low carb.

@user-gz3sg3xg3x Жыл бұрын

Hello doctor, thanks for the informative video, so my recent results are…glucose 5.0 c pep 707 and insulin5.6. My T3 is 3.4 … what does this even mean? I’m drastically losing weight, I have exocrine pancreatic insufficiency and biliary tree narrowing… my tissues, fat and muscle are disappearing before my eyes! 😭💔 I do Keto, and workout regularly, but I’m burnt out. Estrogen dominance thrown in the mix aswell 😭🤦🏼‍♀️

@SpicyLady842 Жыл бұрын

Hugs.

@neeleshsuryawanshi6590 10 ай бұрын

Go for a holistic treatment just Google it

@tonyzhuhai4132 5 ай бұрын

If you are losing too much weight, maybe should stop doing keto and shift to lower carbs ?

@user-gz3sg3xg3x 5 ай бұрын

@@tonyzhuhai4132 was restricted to manage reactive hypoglycaemia so couldn’t have carbs. Still can’t. My beliefs are firmly towards the overgrowth of Candida in the gut 😖

@cas9205 Жыл бұрын

I recently got this test done and my C peptide shows 8.7 but my H1aC is 5.4 and fasting blood glucose is 92 so does that mean I have diabetes or pre diabetic??

@Acts-1322 Жыл бұрын

A1C was found to be a only 27% accurate according to research from the Endocrine Society Meeting 5 years ago, when compared against OGTT. So throw that test in the trash. Erythrocyte (red blood cell) lifespan varies widely from person to person, from 81-146 days actually!- especially when they are damaged from glycation aka sugars sticking to them.

@jdtown6585 10 ай бұрын

Your body is producing a boat load of insulin still. You're lucky. You should start low carb.

@thisisraam06 Ай бұрын

C peptide 1.4 and hba1c 15. What does it mean?

@Mr-hn2bp Ай бұрын

HbA1c of 15 is extremely high, means you are diabetic in a severe stage. Your C-peptide level is way below normal, means your pancreas is not producing enough insulin to keep your blood glucose normal. If you have chronic inflammation and using steroids, your blood glucose will be very high. If you also have no stress and infections, your are likely a candidate for insulin injection.

@thisisraam06 Ай бұрын

@@Mr-hn2bp grade fatty liver, Bulky pancreas and distinted gal bladder is other problems. But I'm not alcoholic and don't have any bd habbits. Another question is C peptide 1.4 is within the range.. as u rightly said I'm on insulin now. Do u think any chance of reactivating pancreas??

@Mr-hn2bp Ай бұрын

@@thisisraam06 Research is ongoing to restore pancreatic beta cells population using a combination of harmine and GLP1. Some positive preliminary results. Examination of dead T1D on decade long insulin use revealed residual pancreatic beta cells. Alcohol and fructose share the same metabolic pathway with the former fermented by yeast. Starches are rapidly digested to form glucose and rapidly absorbed as well. Table sugar or sucrose is digested to one glucose and one fructose. You must be consuming lots of carbs including juices and soft drinks to have great fatty liver and bulky pancreas. Alternatively, you are using increasingly higher insulin doses causing obesity, inflammation and ectopic fats (your fatty liver and pancreas). As this doctor pointed out, insulin injection suppresses pancreatic insulin release，hence low C-peptide level (cosecreted with insulin). C-peptide may be responsible for preserving kidney function and if firmly proven may need to be injected with insulin. Work with your Dr to cut carb intake and adjust insulin dosage accordingly. Good luck and good health.

@GulfamAarif 4 ай бұрын

🎉❤🎉❤🎉❤🎉❤🎉❤🎉❤🎉❤🎉❤🎉Thank you sir❤🎉❤🎉❤🎉❤❤🎉❤🎉❤

@evramirez87 Жыл бұрын

Hello. I just reveived the following results from a test to understand if I have any Diabetes predisposition or risk: - Fasting Glucose: 90 mg/dL - A1c 5,44% - Insuline 3,07 uUI/ml - C Telopeptide 0,829 ng/ml - Glucose Pre/Post Pandrial Pre:89 Post 72 What does C Telopeptide result means?

@jamescalifornia2964 Жыл бұрын

Wishing everyone happy and healthy C-Peptides 😘👌

@dageide6008 Жыл бұрын

It is then important to know when to measured. After a meal, in a fast makes a huge different, and nobody or any doctor tell us!!! Why not???

@DoctorODonovan Жыл бұрын

Would depend on what is it being used to measure / monitor. It's a very case-by-case basis and a one size fits all answer wouldn't be helpful.

@mj625 8 ай бұрын

A pancreas can be removed? And you survive? Seriously?

@Primetime_dads 9 ай бұрын

I got a question, if I eat straight fruit, my sugar will spike up to 180 in a hour, then it will come back down within the 2 hour mark. Had my test done and C-peptide was 1.0 Fasting insulin was 2.2 A1c 5.4 Fasting glucose 92 Just wondering why does my sugar spike so much when I eat sugar 😂. I know this sounds crazy, but I hear that you should be able to eat sugar and only get around 140 at peak if your not insulin resistance. So does this make me insulin resistance? Or is this a normal response?