Antifibrotic treatment in Pulmonary Fibrosis

Рет қаралды 10,773

Жыл бұрын

In this video about antifibrotic treatments for pulmonary fibrosis. Two medications are available (pirfenidone and nintedanib). These drugs may be prescribed for the following indications:
1. Idiopathic Pulmonary Fibrosis - both pirfenidone and nintedanib
Video about IPF: • What is idiopathic pul...
2. Progressive Fibrosing Interstitial Lung Disease (PF-ILD) or Progressive Pulmonary Fibrosis (PPF) - nintedanib only
3. Systemic sclerosis associated interstitial lung disease (SSc-ILD) - nintedanib only
Video about SSc-ILD: • Lung disease in sclero...
These indications may change over time, and new medications may become approved. This information is valid as of April 2023. Please check with your doctor for accurate information in your case.
Antifibrotic medications do not "cure" fibrosis, but they can slow down the progression of the disease. This means that in the long run, being on the medication may be better than not having it. Lung function would be preserved for longer.
There are some potential side effects that I discuss in the video.
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Disclaimers:
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For all viewers/listeners:
The information presented here or in other videos and posts on this channel is not medical advice. These materials reflect general medical knowledge which may not apply to your individual case. If you have health concerns, please see your own doctor or other healthcare provider without delay.
For medical professionals:
You must use your professional judgement when treating your patients. The information presented in this and other videos/posts on this channel is for general medical education only. It may not apply to all patients or clinical scenarios.
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Пікірлер: 28

@DrStefanCristianStanel 10 ай бұрын

I started another channel dedicated to Interstitial Lung Diseases (ILD) and lung fibrosis if you are interested: www.youtube.com/@InterstitialLungDisease

@jamessang5027 Ай бұрын

Fibrosis is caused by nutrient deficiencies , specifically vitamun a , vitamin d and zinc deficiencies

@naomiweida2384 10 ай бұрын

This is a great lecture. My dad was recently diagnosed with IPF by Dr. Boltax at The U (we were overly impressed with him and his team). This medication is amazing, we choose Ofev because my dad wants to stay out in the sun and stay active. It will be nice when more information comes out about the medications regarding drug to drug interaction.

@IntendJOY 9 ай бұрын

Greatly helpful! Thank you so much

@lorismith5369 10 ай бұрын

Thank you!

@ireneeickenhorst2326 11 ай бұрын

Thank you, these videos have been so helpful for me. I will be 86 in 3 days I opted to not do the medication at this point in my life I look for ways to enjoy it as best as possible and did not want to deal with the side effects.

@DrStefanCristianStanel 11 ай бұрын

Thank you for your message, this can be a perfectly reasonable choice, I wish you all the best and hope you are having good support from your healthcare team

@kosalabandaranayaka8333 2 ай бұрын

Great video doctor, is there any updated treatments? My father has ipf and on perfinidone, has a lot of side effects and he is getting weaker as a result of loss of Appetite and loss of sodium

@francasimonetta3849 5 ай бұрын

Thank you so much I was recently diagnosed and I am very scared. I’m 62 years old. I have psoriatic arthritis and was on Humira and I think it was Dehm that brought it on. I could see my rheumatologist on Monday and will go from there but I’m starting to have a hard time breathing. Thank you so much for explaining everything.

@padmeshsethuraman5617 Ай бұрын

I’m 66 year old Indian male. In my annual check done last month, chest X Ray showed some shadow (scarring). I do not have breathing difficulties. I do not have clubbing of nails. No coughing. So my GP did not advise any further investigation. My son insisted for further checking. I consulted a pulmonologist a week later. He prescribed Chest CT scan and 3 blood tests. Based on the reports he advised no further treatment. I have psoriasis and mild psoriatic arthritis since 36 years. I’m taking a probiotic to keep my skin from flaring. AxisBiotix. I’m hoping and praying that the situation does not worsen. I’m taking 50mg of Zinc picolinate once daily as psoriasis patients loose zinc in the scales and are low in zinc. Low zinc can cause fibrosis

@janball3356 10 ай бұрын

I have been diagnosed with ipf and wonder if reflux could have caused it. I was prescribed Omeprazole but they made me vomit and l was wary of taking them anyway, so l didn't. I use a bed wedge and sleep on my left side and occasionally take Gavescon for stomach acid. But still now have IPF. Also do inhalers help with this desease. Thank you.

@aaronwalcott513 10 ай бұрын

"One day" is now. There are a few vids already out on YT that suggest autophagy of the scarred tissue (achieved by fasting) and replacement of phaged tissue with stem cells (achieved by fasting). Of course more research into the duration of the fast(s) and the diet after to prevent refeeding syndrome is needed. But it seems promising.

@joshuagriffin9054 4 ай бұрын

What are those videos called

@digitalrajkot1465 11 ай бұрын

Is getting tired a side effect of fibrosis? With medicine what is the survival rate?

@bimalbhattacharya856 11 ай бұрын

Sir how long a patient survive with ILD having antifibrotic drug from its early stage of diseases ?

@masonryjoe 2 ай бұрын

What about serrapeptase ?

@ceciliamok3579 Жыл бұрын

After taking prifenidone for two weeks, my husband found breathing worse than before is this the side effect, he takes 2 capsule one time, if one capsule at a time not so bad

@Annliyalovesyou 11 ай бұрын

Ofev dosage is one cap dupe two times a day Please consult with your Dr.

@moviestelugunow2931 10 ай бұрын

Features are consistent with Fibrosing Interstitial Pneumonia with Microscopic Honeycombing and Peripheral Fibrosis with Smooth muscle Prominence. Fibroblast Focus Activity is Low. Possibility of usual Interstitial Pneumonia is Considered Sir this is my condition may i recover from it is any cure or treatment for this my age is just 22 years only please help me to figure this out sir suggest me me the treatment and medicine sir

@joselenetancingco4828 8 ай бұрын

use mohringa powder with honey .make it your coffee everyday.

@TJ-Dives 3 ай бұрын

You do not mention kidney failure, liver problems with pirfenidone.

@DrStefanCristianStanel 2 ай бұрын

these are potential problems with most medications. with antifibrotics such as pirfenidone or nintedanib we tend to monitor liver and kidney function with blood tests every 3 months and if no changes we continue treatment