Drugs for Asthma Treatment

Рет қаралды 101,641

8 жыл бұрын

This is a short video on drugs used to treat the obstructive airway disease asthma.
I created this presentation with Google Slides.
Image were created or taken from Wikimedia Commons
I created this video with the KZfaq Video Editor.
ADDITIONAL TAGS:
Antigen/Irritant/Trigger
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
Sympathetic (Î²2-mediated) Bronchospasm
Mediators
DRUGS FOR ASTHMA
Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (Î²2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
Î²2-agonist
(albuterol)
long acting Î²2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)
Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (Î²2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
Î²2-agonist
(albuterol)
long acting Î²2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)
Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (Î²2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
Î²2-agonist
(albuterol)
long acting Î²2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)
Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (Î²2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
Î²2-agonist
(albuterol)
long acting Î²2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)
short acting beta two agonist beta2 betatwo b2 btwo agonist short acting muscarinic cholinergic agonist

Пікірлер: 56

@khankhan-cw2bq 5 жыл бұрын

Concise and amazing lecture ....

@Lena-nl2on 6 жыл бұрын

Amazing video, now I don't have to worry about tmw's PBL case. Thanks a lot!

@wesamalramady2198 7 жыл бұрын

you are awesome thank you do u have more lectures?

@Suesaysboo 7 жыл бұрын

amazing video

@marwanel-halawany2879 4 жыл бұрын

Really helpful video thanx a lot

@nonnieculture1303 3 жыл бұрын

This was very helpful, thank you 🙏🏽

@stephaneabramowicz4658 7 жыл бұрын

great stuff !

@esranana9696 8 жыл бұрын

Useful one ..

@thabisonyawo500 7 жыл бұрын

thanks man very helpful video for my pharmacology

@vernisvet 6 жыл бұрын

Very useful. *one very important remark* You don't spray Albuterol down your throat. You inhale the medication using a spacer so it goes to the bronchi. That will relieve your asthma exacerbation.

@azersamaali2016 3 жыл бұрын

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@cometoChrist 4 жыл бұрын

Thank you so much!🙌🏾🙌🏾

@Sam_1964 3 жыл бұрын

Good lecture. Instead of Sympathetic put anti sympathetic causes Bronchospasm. Good job

@athanaselisha1617 7 жыл бұрын

nice one

@dhruvkhola 3 жыл бұрын

Thank you Sir 100% useful

@tonadia2 7 жыл бұрын

Thank you!

@hazen2405 7 жыл бұрын

Thank you! Excellent overview!

@christianstaehr91 7 жыл бұрын

Cheers ! Great overview

@pharmdpharmacy8203 6 жыл бұрын

kzfaq.info/get/bejne/it-dYJVh1J2qo5s.html

@ashwaksaid5422 7 жыл бұрын

Thank you

@HafizahHoshni 7 жыл бұрын

thank you!

@lharris4791 6 жыл бұрын

any more vids? simply perfect...

@deborahkibelion7821 7 жыл бұрын

thank you

@ishww 4 жыл бұрын

Thanks !

@anoodalshammari4615 7 жыл бұрын

thank u so much

@daniyalbang7029 7 жыл бұрын

nice

@madumalka5114 5 жыл бұрын

Doesn''t Beta2 cause bronchodilation?

@tabbypt6079 4 жыл бұрын

What of mast cell stabilizers?

@hilalelgargini1846 6 жыл бұрын

Sympathetic bronchospasm? Did I miss the big picture from the beginning?

@aloysschikelgruber9683 4 жыл бұрын

Probably just a slip of the tongue as he does rectify it later on by stating that it is the reflex parasympathetic bronchospasm

@patriciaanton7550 4 жыл бұрын

I'm researching best natural treatment for asthma and discovered a great resource at Laken Chest Remedy (look it up on google)

@zhafribaharuddin4442 5 жыл бұрын

guys, i dont understand, why b2 sympathetic can cause asthma in this vid? is it suppose to bronchodilate? and why IL5 can cause histamine too? should be IL4 right? or I am wrong. someone plz help me

@richardfriedel2248 3 жыл бұрын

To cure asthma with acupressure: 1) Press lip with a finger and note how inhaling through your nose is facilitated 2) Make a habit of breathing in with lip pressure to stop asthma. A Google search for asthma pressure points shows points on lips. . Asthma causes airway remodeling but this is cured in time by correct breathing. That is my experience.

@lifelee2030 7 жыл бұрын

thankyou, it is really helpful but at some points you were speaking very fast that was making words difficult to understand. :)

@psychtogo4291 6 жыл бұрын

I love your american accent and the way you say RECEPTOR :-) :-* Best regards from Munich,Germany

@fccms25 6 жыл бұрын

B2 sympathetic mediated bronchospasm?...don't think so. B2 is bronchodilator. Nice try.

@pharmdpharmacy8203 6 жыл бұрын

kzfaq.info/get/bejne/it-dYJVh1J2qo5s.html

@khankhan-cw2bq 5 жыл бұрын

Yes u r right i also note this ....can someone help

@richardfriedel2248 4 жыл бұрын

Just time-consuming nonsensical pseudoscience like bloodletting in the past, which may well have killed George Washington. Asthma eradication: Nose breathing and no inhalers and also understanding reflexes. According David P. Strachan it is unlikely that trends in either outdoor or indoor air pollution have contributed substantially to the rise in prevalence of asthma and allergic disease in recent decades, Then we have the asthma-paradox that for many decades more asthma drugs have led to more asthma. Although acupressure treatment for asthma is widely recommended the points are mostly not on the face. However a distinct positive effect on breathing opening up lung airways to counter asthma with wheezing may be felt on pressing the lips together. This means we have a simple back to nature approach. Accordingly an important cause of asthma is asthma drug addiction. So we are left with asthma paradox that more drug treatment has long been associated with more asthma for decades on end.

@HafizahHoshni 8 жыл бұрын

thank you!