E2 Reaction Mechanism - Hoffman Elimination vs Zaitsev's Rule

No video

E2 Reaction Mechanism - Hoffman Elimination vs Zaitsev's Rule

Рет қаралды 281,945

The Organic Chemistry Tutor

Күн бұрын

Пікірлер: 73

@TheOrganicChemistryTutor Жыл бұрын

Organic Chemistry PDF Worksheets: www.video-tutor.net/orgo-chem.html Full-Length Exams and Worksheets: www.patreon.com/MathScienceTutor/collections Next Video: kzfaq.info/get/bejne/la5ndLGWv5rNfGw.html

@9ball25 3 жыл бұрын

zoned out of my three hour class and had no idea what was going on. Watched this 12 min video in class and now I'm ahead of everyone.

@lmthagod328 Жыл бұрын

I swear most organic chemistry lectures are never understandable 😂

@kylet6612 Жыл бұрын

Yes you are correct! My teacher does not teach in organized way. We learn simple concepts but given advanced problems lol

@jul2447 Жыл бұрын

@@lmthagod328 😭

@krazykanpuriya Жыл бұрын

@@kylet6612My teacher too is like that 😭. Proof that we all live the same life 😂.

@raghunandanbs2005 9 ай бұрын

3 hours I've been zoning out my whole college life , lyf sucks for me .

@GurleenKaur-xy6xv 8 ай бұрын

not sure how my professors make it so complicated when you can clearly explain it to us in such clarity

@galyavakian 2 жыл бұрын

I think you will save my life for my medical school entrance exam!! I really struggled in Organic Chemistry during finals!

@domoo2639 2 жыл бұрын

Listen i am struggling. Chemistry was never my strongest science ! and i need this class to stay in my nursing program !

@maximilianavila7510 2 жыл бұрын

@@domoo2639 hope you succeed!

@advayargade746 2 жыл бұрын

Thanks for clearly explaining the nooks and corners which are not that commonly taught. Really helpful!

@ezaaax811 Жыл бұрын

Lmaoo sameeeee 😂😂😂

@snazzyratking6466 6 ай бұрын

Oh my gosh I’ve been looking for the fluorine example everywhere! Thanks for explaining!

@charlykhalil128 3 жыл бұрын

Best Organic Chemistry Tutor EVERRRRR! I love u man! I salute you!

@aliciapark523 Жыл бұрын

So simple and straight to the point!

@frhneil1463 3 жыл бұрын

hello sir, i'm wondering what it's take and how long it's take for you to understand this stuff let along teach it clearly in the most simple way ever? I'm amazed. I want to understand stuff till I can explain it just like you did.

@coolspike7659 2 жыл бұрын

You will, The key is to NEVER GIVE UP !!! You are capable of doing what he does, and so much more !!

@Mirwhosane Жыл бұрын

@jewelokwuosa9413 5 жыл бұрын

Thank's so much! quiz on this tomorrow, really helped : )

@alessiailas4929 2 жыл бұрын

Same here now and it's midnight 😭

@jewelokwuosa9413 2 жыл бұрын

@@alessiailas4929 good luck!

@carolo6098 Жыл бұрын

@@alessiailas4929 1am 😅

@atharvmathur91 2 жыл бұрын

Thank you soo much helped me a lot for my 12th grade exams😀

@grapesjuice6860 2 ай бұрын

I pray for this man alot

@akashprofile Жыл бұрын

A lot of thanks, Brother! You cleared my prolong confusion.

@shaghaieghtaheria9453 3 жыл бұрын

I owe my life to you sir,

@Ankitshbj 10 ай бұрын

Any JEE/NEET aspirant☝️☝️☝️

@advaitkolhe8164 3 ай бұрын

Haa bhai, JEE 2025. Halo arenes and amines ke PYQ me bohot use hota hai E2 mechanism

@nikodg194 5 жыл бұрын

The reason why the Hoffman product forms while e2 elimination of fluorine is due to enthalpy of the fluorine carbon and that's why it dont want to go easily at least that's what my profesor says

@jellyfam1197 2 жыл бұрын

I have two orgo professors both highly respected in their fields, both had different reasoning. Consensus is that no one exactly knows, there’s 2-3 hypotheses as to why Fl- is Hoffman

@lizareizis2517 2 жыл бұрын

what makes a good or bad leaving group?

@JamesKing-pl2xu 2 жыл бұрын

The size i believe because its size is what determines the polarizability (ability to stabilize the charge). Therefore I- or Br- are better leaving groups than say F- and Cl-

@rohankrishna9228 4 жыл бұрын

Its excellent sir I learned a lot thank you so much sir

@alondraherrera4170 2 жыл бұрын

didnt really explain what an e2 reaction is and how it works, do you have a video on that?

@user-xh5eg6fi5m 11 ай бұрын

Thanks alot all my doubts is now cleared 😊

@Whoooooo_tao 27 күн бұрын

Dude saved my finals for the 5th time

@uthpalp3807 6 жыл бұрын

Helped a lot.. thanks

@user-zt4qr7mz4f 2 жыл бұрын

You're a lifesaver

@yuridanylko Жыл бұрын

Say there is a molecule (a triene) in which a bulky base is used to to create a hoffman product via an E2 reaction. The first option will result in a cis disibstituted pi bond. The second option will result in a geminal disubstituted pi bond. There is also a trisubstituted pi bond possible towarss the middle of the alkene. Will the major product be the cis or geminal alkene? What drives this? Stability of the carbocathion? Steric hindrance? Stability of the end product?

@Hrishikesh..000 Жыл бұрын

Thank you bro Have a great day....

@sakshamshrivastava4221 Ай бұрын

All doubt clear sir thnks❤

@user-qd1mz3qn9t Жыл бұрын

You are the BEST ! Thank you very much !

@jesusmrosario-claudio4104 3 жыл бұрын

Thank you once again.

@albertlee8586 10 ай бұрын

If E2 is favored with a polar aprotic solvent is there a reason you use methanol for many of the solvent examples? Thanks for the video, super helpful for a quick MCAT review! Edit: type

@annablueseas 10 ай бұрын

i was thinking the same thing! i was so confused

@shaktisinghhemant1937 2 жыл бұрын

Thank you so much

@ilickcatnip 3 жыл бұрын

Great explanation!

@caloman5191 2 жыл бұрын

super helpful.

@bobu5213 Жыл бұрын

So in both the E1 and E2 reactions, both the minor and major product always form if possible?

@muslimgirl1481 Жыл бұрын

Yes bcz both are regioselective ( can give major and minor products) and sterioselective ( can form cis and trans product) also.

@puneetgill4064 3 жыл бұрын

for -O-CH(CH)3, will its preference be 1>2>3 because of steric hindrance?

@maureene7138 3 жыл бұрын

It will actually prefer 3>2>1 for E2 and E1

@xxcoltonxx2540 10 ай бұрын

What about when its an alkyl group connected to a benzene ring, kinda need to know how to find the minor product there don't we....

@David-fh6rr 6 жыл бұрын

But why does is the conjugated product formed? The MeO- doesn't know it has to make the conjugated product, it has no brain. Does the double bond already draw electron density from the a-CH bond to make it more likely to break before it happens?

@ashueje6416 2 жыл бұрын

Both the products are formed in the reaction the conjugated diene is majorly formed as it is more stable . the reactions occus so as the products have a lower Potential energy than the reactants is their is reconance then the stability of the alkene is more so this is the only reason why a cinjugated di ene is formed in major.

@carlovaldes259 5 жыл бұрын

Thanks !!!

@theg.o.a.t1014 2 жыл бұрын

Now I am maestro after 12min watching

@kraken6161 9 ай бұрын

now is hoffman product the minor or the major because once the minor was hoffman then the major was hoffman

@sakshamshrivastava4221 Ай бұрын

Thank sir

@Dr.DiMiTri.710 Жыл бұрын

You are officially the final evolution of Bill Nye

@KshitijPunani 6 ай бұрын

Thanks nro

@FBR2169 4 жыл бұрын

6:22 why is the major product Hoffman????

@jadesamanta7717 4 жыл бұрын

The big, bulky base (tert-butoxide) cannot penetrate into the center of the molecule to deprotonate those Hydrogens (remember, the space-filling model: those electron clouds in the middle carbons are large). So, the only H the base can reach are the terminal ones on the end. Therefore, the Hoffman product forms, even though its technically less stable than Zaitsev. It is the only E2 reaction that can feasibly take place there.