This video shows Ectopic pregnancy with Endometrial Hyperplasia.
Many women are able to become pregnant with endometrial overgrowth, but it is important that you talk to your doctor regarding therapy options that rectify your fertility.
The uterus is enlarged in ectopic pregnancy. Following implantation, the trophoblast produces hCG which maintains the corpus luteum. The corpus luteum produces estrogen and progesterone which change the secretory endometrium into decidua. The uterus enlarges up to 8 weeks in size and becomes soft.
“Ectopic pregnancy is diagnosed when the gestational sac with a live fetal pole or yolk sac is found outside an empty uterine cavity,” says Dr. Khalife. “Sometimes, diagnosis can be challenging if the ectopic pregnancy is in its early stage and the sac is not yet visible by ultrasound.”
A thickened endometrial lining after miscarriage is a normal finding. Therefore, based on the available evidence, clinical signs and symptoms rather than endometrial thickness should guide treatment decisions. None of our subjects with an endometrial thickness greater than 15 mm required surgical evacuation.
Often measurements of hCG blood levels are repeated to help make the diagnosis. Progesterone levels in the bloodstream rise very early in the course of a pregnancy. Low levels of this hormone are frequently associated with an abnormal pregnancy, such as an ectopic pregnancy or an impending miscarriage.
One of the more common causes of changes in endometrial thickness is pregnancy. Women who are having an ectopic pregnancy or who are less than 5 weeks pregnant may show signs of a thickening endometrium.
The absence of an intrauterine gestational sac on abdominal ultrasound in conjunction with a β-hCG level of greater than 6,500 mIU per mL suggests the presence of an ectopic pregnancy.
In a normal pregnancy, the β-HCG level doubles every 48-72 hours until it reaches 10,000-20,000mIU/mL. In ectopic pregnancies, β-HCG levels usually increase less. Mean serum β-HCG levels are lower in ectopic pregnancies than in healthy pregnancies. No single serum β-HCG level is diagnostic of an ectopic pregnancy.
Symptoms of an ectopic pregnancy usually develop between the 4th and 12th weeks of pregnancy. Some women don't have any symptoms at first. They may not find out they have an ectopic pregnancy until an early scan shows the problem or they develop more serious symptoms later on.
Signs of ectopic pregnancy at 7 weeks
Ectopic pregnancy
abnormal vaginal bleeding.
fainting or feeling faint or suddenly dizzy.
low blood pressure.
rectal pressure.
shoulder pain.
severe, sharp, sudden pelvic pain.
If it's not diagnosed in time, generally between 6 and 16 weeks, the fallopian tube will rupture. This is long before a fetus could survive outside of the mother's body. The sad truth is that when a pregnancy is ectopic, the fetus will not survive.
A b-hCG increase of more than 53% in 48 hours suggests abnormal pregnancy, either ectopic or failed intrauterine pregnancy. Abnormal rises in b-hCG only have 36% sensitivity and 65% specificity for detecting ectopic pregnancy. This is because ectopic pregnancies can have normally rising b-hCG levels 21% of the time.
Patients with normal intrauterine pregnancies had serum progesterone levels greater than 20 ng/mL (mean = 30.9 ng/mL) while all patients with ectopic pregnancies had progesterone levels less than 15 ng/mL (mean = 5.7 ng/mL).
Endometrial hyperplasia is increased growth of the endometrium. Unlike cancer, mild or simple hyperplasia can go away on its own or with hormonal treatment. The most common type of hyperplasia, simple hyperplasia, has a very small risk of becoming cancerous.
In many cases, endometrial hyperplasia can be treated with progestin. Progestin is given orally, in a shot, in an intrauterine device (IUD), or as a vaginal cream. How much and how long you take it depends on your age and the type of hyperplasia. Treatment with progestin may cause vaginal bleeding like a period.
A tubal pregnancy - the most common type of ectopic pregnancy - happens when a fertilized egg gets stuck on its way to the uterus, often because the fallopian tube is damaged by inflammation or is misshapen.
An unruptured corpus luteum cyst or may be mistaken for an ectopic gestational sac, and a ruptured corpus luteum cyst may produce free pelvic fluid suggesting ruptured ectopic pregnancy. The presence of ANY cul-de-sac fluid indicates ectopic pregnancy until proven otherwise.