A patient with exertional angina was found to have a severely calcified distal RCA lesion that could not be crossed by any balloons and was referred for repeat PCI attempt. The RCA was engaged with an AL1 8 French guide catheter. We were unable to cross the lesion with a guidewire, despite using a microcatheter and multiple wires with different bends at the tip. Eventually we used a Sasuke dual lumen microcatheter and were able to cross with a Gladius Mongo wire. However, the lesion was also “balloon uncrossable”. A Sapphire could not cross, despite using a deep seated guide extension. After grenadoplasty a Mamba Flex was delivered through the distal RCA lesion, allowing insertion of a Viper Flex Tip wire. After several rounds of orbital atherectomy the lesion was successfully crossed by balloons and expanded well. After DES implantation an excellent final result was achieved as confirmed by IVUS.