Join Dr. Chris Derderian from the Colorado Fetal Care Center at Children's Hospital Colorado as he delves into the critical topic of fetal growth restriction (FGR) in this informative video. Fetal growth restriction, characterized by poor in utero growth and a fetal weight below the 10th percentile for a given gestational age, impacts 10 to 15% of pregnancies globally and is a leading cause of nearly 50% of stillbirths. With long-term consequences ranging from neurodevelopmental issues to cardiovascular diseases, understanding FGR is crucial. Dr. Derderian explains the multifaceted risk factors associated with FGR, including maternal, fetal and placental origins, while highlighting the complexity of diagnosing and treating this condition due to its often-idiopathic nature.
Diving deeper, Dr. Derderian shares his insights into why fetal growth restriction remains a challenging field of study and the limitations of current research models. As a pediatric and fetal surgeon, his clinical experiences, especially with conditions like twin-to-twin transfusion syndrome, have fueled his passion for researching FGR. In his lab, the focus is on microRNAs and their role in placental invasion and angiogenesis, which are crucial processes affected by FGR. Although the path to developing effective therapeutics for FGR is long, Dr. Derderian's work represents a hopeful step toward understanding and eventually treating this complex condition.
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