Finasteride and dutasteride in androgenetic alopecia - selected topics

  Рет қаралды 8,544

prof. Lidia Rudnicka

prof. Lidia Rudnicka

Жыл бұрын

Finasteride and dutasteride in androgenetic alopecia - selected topics
The basic mechanism of action, history, adverse effects, 0.25% topical finasteride spray
A book about androgenetic alopecia:
Androgenetic Alopecia From A to Z: Vol. 2 Drugs, Herbs, Nutrition and Supplements
by Konstantinos Anastassakis
amzn.to/3YDM4hy
* Introduction
* 5 alpha reductase inhibitors
* finasteride and dutasteride
* sexual adverse effects & finasteride or dutasteride
* finasteride & the breast abnormalities
* topical finasteride

Пікірлер: 101
@doctorsanakanasskinandbeau3655
@doctorsanakanasskinandbeau3655 Жыл бұрын
💐💐💐💐💐
@lidiarudnicka9370
@lidiarudnicka9370 6 ай бұрын
🙂
@profLidiaRudnicka
@profLidiaRudnicka Ай бұрын
Thank you!
@Merth667
@Merth667 Жыл бұрын
Underrated videos. Thanks for posting. I hope the video about efficacy of these drugs is still in the pipeline.
@halinaderevianko5312
@halinaderevianko5312 6 ай бұрын
Dziękuję Pani Profesor
@profLidiaRudnicka
@profLidiaRudnicka 6 ай бұрын
Dziękuję bardzo za feedback! 🙂
@user-sh8yh4ij6f
@user-sh8yh4ij6f 5 ай бұрын
Very Very excellent
@profLidiaRudnicka
@profLidiaRudnicka 5 ай бұрын
Thanks a lil 🙂
@sarahhassan5727
@sarahhassan5727 20 күн бұрын
Thanks professor 🎉🎉
@profLidiaRudnicka
@profLidiaRudnicka 19 күн бұрын
Thank you 😊
@MohamedIsmail-yr9my
@MohamedIsmail-yr9my Жыл бұрын
I miss you soooooo much
@sasindusri5503
@sasindusri5503 Жыл бұрын
Good program thinks madam ❤
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Thank you!
@zahidshah128
@zahidshah128 Жыл бұрын
Can U Please make ur Expert opinion Post for Safe Donor Area Thanks
@MohamedIsmail-yr9my
@MohamedIsmail-yr9my Жыл бұрын
I hope you are fine
@akankshaugale-dz8if
@akankshaugale-dz8if Ай бұрын
nice
@profLidiaRudnicka
@profLidiaRudnicka Ай бұрын
Thanks!
@chinchwen
@chinchwen Жыл бұрын
Very informative video, thank you Prof!
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Thank you!
@olamicek2580
@olamicek2580 Жыл бұрын
Pani doktor, Może w kolejnym odcinku o leczeniu lzs skory głowy? Mimo dostępnych leków nadal pozostaje utrapieniem wielu pacjentow
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Dziękuję bardzo. Wpisane na listę tematów do opracowania. Bedzie tu lub na kanale polskojęzycznym 😊
@MrsPabbathi
@MrsPabbathi Ай бұрын
Thank you Madam. Very useful please post more research about oral minoxidil and finasteride and how much dutesteride dose is better
@profLidiaRudnicka
@profLidiaRudnicka Ай бұрын
Thank you! Everyone is different, so there is no dose that is best for everyone….
@tudorgames6598
@tudorgames6598 Жыл бұрын
Hey doc, i would love a video talking about how these medications affects the hair cycle, because when you are suffering hair miniaturization the sync of how this happens on each hair is different, so when using these types of dht blockers these miniaturized hairs are putten into the anagen phase for longer time. The question is i've seen people saying that their hair starts synchronizing again and they start experiencing a "seasonal shedding" that makes their hair looks thinner before getting thicker again, especially close at one year and two year mark after starting these medications. Would love to know what you think of this topic :). Thank you!
@profLidiaRudnicka
@profLidiaRudnicka 6 ай бұрын
This may be the case with another medication, not finasteride
@HaeppyUnni
@HaeppyUnni Ай бұрын
can you please make video on lichen plano pillairs LPP/ scarring alopecia
@profLidiaRudnicka
@profLidiaRudnicka 27 күн бұрын
I will! As soon as I get some time to put it together! Thanks for the suggestion :-)
@jaxxiloulou2358
@jaxxiloulou2358 Жыл бұрын
Thank you got an informative video. I didn’t realise that type 3 isoform of 5-alpha reductase was present in significant levels in hair follicles (always thought that it’s preferred substrate would be androstenedione instead of testosterone. I also thought both finasteride and dutasteride were quite potent inhibitors of type 3 anyway, so in my mind it’s always been finasteride against type 2, and dutasteride against type 1 and 2 as far as AGA goes. So I’ve learned something new.
@justindoud251
@justindoud251 Жыл бұрын
0
@justindoud251
@justindoud251 Жыл бұрын
00
@justindoud251
@justindoud251 Жыл бұрын
00
@justindoud251
@justindoud251 Жыл бұрын
00
@justindoud251
@justindoud251 Жыл бұрын
00
@mateuszmisiurski3144
@mateuszmisiurski3144 10 ай бұрын
Pani doktor, czy gdy przy stosowaniu finasterydu efekt jest średni mozna pomyśleć o dutasterydzie?
@profLidiaRudnicka
@profLidiaRudnicka 10 ай бұрын
Taką decyzję podejmuje się zawsze z dermatologiem, który prowadzi leczenie.
@user-wt5if6rx8m
@user-wt5if6rx8m 7 ай бұрын
The end of this video gets me because I don't know what to do anymore. I wish dr. Rudnicka could see me herself. I've been to more than 10 doctors, 05 being 'specialists' who sent me back home telling me 'there's not patterns, there's nothing wrong with your hair'. No one will close a diagnosis so won't let me try a DHT blocker. I've been losing hair globally in my entire scalp, especially sides and even on the back, however this has been happening for years (progressively) and not in clumps, so it's not alopecia areata or telogen effluvium. I believe genetic hairloss is the only possibility left. I feel neglected and like I've wasted too much time already, losing ground.
@profLidiaRudnicka
@profLidiaRudnicka 7 ай бұрын
Where do you live? Maybe I know a hair expert in the area
@janecroft
@janecroft 5 ай бұрын
Do you No an expert in Germany for female androgenetic Hair loss?
@ridhimaagarwal6142
@ridhimaagarwal6142 5 ай бұрын
Maam.. what’s your opinion on bicalutamide for acne and hair loss? I am 41 and female. I was on finasteride 5 mg since 6 years and was doing fine. But last few months I was noticing that my scalp had again started showing. So my doctor switched me to bicalutamide 25 mg daily. But ma’am after 2 months of taking it, I feel my acne is only getting worse. For hair I know that it will take time. What should i do?
@profLidiaRudnicka
@profLidiaRudnicka 5 ай бұрын
I rarely use it but it may be an option
@AdamOakmanComposer
@AdamOakmanComposer Жыл бұрын
Dobry wieczór, dzisiaj natrafiłem na kanał Pani profesor i muszę tak ja przedmówcy serdecznie podziękować za cenne materiały jakie Pani tworzy. Ze względu na to że problem AGA dot. mnie osobiście i mojej narzeczonej (narzeczona w trakcie diagnozy) to interesuję się tematem dosyć intensywnie jak na amatora, ale nadal mam jeszcze zagwozdki o które chciałbym zapytać. Obecnie przyjmuję finasteryd w dawce 1,25mg dziennie z w miarę dobrymi efektami, miałem epizody w których próbowałem stosować na skórę głowy minoxidil, ale z mało zauważalnym efektem. Zainteresowałem się fragmentem w którym wspomniała Pani o doustnym minoxidilu który wydaje mi się wygodniejszą formą do regularnego stosowania. Czy minoxidil doustnie stosuje się także u kobiet? I czy w polskich aptekach minoxidil doustny jest dostępny, ew. pod jaką nazwą? Pozdrawiam serdecznie
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Bardzo dziękuję. Zachęcam do innych filmów na moich kanałach, które zapewne odpowiedzą na te pytania, w szczególności pierwsza cześć tego materiału: kzfaq.info/get/bejne/iJxoaaypr7eUc58.html
@AdamOakmanComposer
@AdamOakmanComposer Жыл бұрын
@@profLidiaRudnicka dziękuję za odpowiedź, wydaje mi się że to nie ten link
@annabob5083
@annabob5083 Жыл бұрын
Witaj pani Lidia! It that possible to have an appointment with you or with any dermatologist in Klinika Dermatologii i Wenerologii in Warsaw? And how to call to them?
@profLidiaRudnicka
@profLidiaRudnicka 10 ай бұрын
Yes, just call and make an appointment
@nicolaslorenzo78
@nicolaslorenzo78 Жыл бұрын
Thank you for the video I'm already on finasteride 1mg a day for 5 months Can I combine with dusdasterine with finasteride and if yes how much and how often ? Thank you in advance
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
No, this is not a usual treatment regimen, because both drugs have a similar mechanism of action
@Maddy-95640
@Maddy-95640 6 ай бұрын
hi doc, is the result of hormone DHEAS a definitive result for androgenic alopeacia, my result is normal but I still lose hair from the crown area a lot. P.S. I'm female.
@profLidiaRudnicka
@profLidiaRudnicka 6 ай бұрын
I am not sure that I understand the question. If the question is whether hair loss is reversible, the issue is complex, but it may be reversible
@Mummybear3-yf2br
@Mummybear3-yf2br 8 ай бұрын
Excellent post, thank you. Can you suggest appropriate dosage for using finasteride in women? My doctor has prescribed 1 x 5mg tablet per WEEK (not day).
@iamimperfectionperfected4
@iamimperfectionperfected4 5 ай бұрын
That's correct. He's having you take it just once a week instead of daily. I mean you can cut your pill into 5 pieces and take it 5 times a week.
@mirasingh7428
@mirasingh7428 5 ай бұрын
Does finastrade works in women ? Please reply
@Mummybear3-yf2br
@Mummybear3-yf2br 5 ай бұрын
It is frequently used by women with female pattern hair loss as a DHT blocker. @@mirasingh7428
@anos195
@anos195 Жыл бұрын
Hey doc , i have alopecia and i used minoxidil and finasteride for one year 8month and the finasteride now is Cut off from the market switched to dutasteride injections every 10 days i going to clinic for injection for 6 sessions -May question now my plan its good or no ,because i stop the finasteride and make duta sessions and how many time to back my hier its good ? Thanks doc .
@profLidiaRudnicka
@profLidiaRudnicka 6 ай бұрын
Yes, switching from finasteride to dutasteride is ok.
@saleemab2012
@saleemab2012 Жыл бұрын
Thank you prof. for explanation about Finasteride and dutasteride My question is ..for how long we can use these medications systemically ? And can we use Finasteride or dutasteride 3 days/ wk to decrease the chance of side effects without affect kn efficacy..? Thank uou so much
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Thank you. As per available data there are no time limits. Dutasteride 3/week was discussed because of the longer half-life but there are no studies about efficacy of this type of dosing
@samdaniels2
@samdaniels2 10 ай бұрын
The chances of side effects are extremely low. Why don’t you just try it everyday and see how that goes?
@eldakupe5233
@eldakupe5233 Жыл бұрын
Hello I have fibroadenomis in my breast and If I treat my androgenetic alopecia with minoxidil 5% , does have any side effect in my breast?
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
In my opinion not , but the opinion of the doctor who takes care of your breast condition is most relevant
@kaushikdutta9000
@kaushikdutta9000 Жыл бұрын
I am a patient of OCD and taking psychotic medicine last 6 years. My main concern is my hair fall started when I was 14. Now I am 30years old. Totally bald. Probably Norwood 7. But the problem is I have losing hair from lower and side portion of the head. Maybe retrograde alopecia. And also losing beard.almost 70% of my beard density has gone and losing my beard line. I saw many dermatologist but nothing works. I just want to know is it treatable?
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
You definitely need a diagnosis. There are at least few conditions which cause this type of hair loss
@kaushikdutta9000
@kaushikdutta9000 Жыл бұрын
@@profLidiaRudnicka I am from india. How could I contact you?
@lisq34
@lisq34 Жыл бұрын
Pani Profesor proszę o poradę - przyjmuję finasteryd 1mg doustnie a poziom DHT nie dość, że się nie zmniejszył po kilku miesiącach, to jest większy (ok 1500). Dlaczego, co robić?!
@profLidiaRudnicka
@profLidiaRudnicka 4 ай бұрын
Analiza stężenia DHT w surowicy nie jest parametrem skuteczności klinicznej finasterydu
@lisq34
@lisq34 4 ай бұрын
@@profLidiaRudnicka dlaczego, skoro powinien blokowac synteze dht? Jak inaczej sprawdzic skutecznosc? Ps: po roku stosowania ponowilem badanie dht - teraz jest bardzo male, ok 250.
@Judiopolis
@Judiopolis Жыл бұрын
What does it mean to see a red thread like strand on trichoscopic view. Noticed this on three different clients
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Thanks for asking. I would need to see an image...
@Judiopolis
@Judiopolis Жыл бұрын
@@profLidiaRudnicka image has been sent to your Instagram DM ma'
@MohamedIsmail-yr9my
@MohamedIsmail-yr9my Жыл бұрын
Where are you prof lidia
@i.112
@i.112 Жыл бұрын
Could you please discuss what types of hair loss are associated with both head and pubic hair loss? I’ve been shedding for a year ( 25 yr old girl) and now my pubic hairs are falling :(
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Thank you. This is complex, especially with no details. In a young person the most probable case may be alopecia areata, whereas in a 40+ woman it may be for example lichen planopilaris (Grham Little type). Some skin diseases may be associated with diffuse hair loss....
@i.112
@i.112 Жыл бұрын
@@profLidiaRudnicka I would love to become a patient at your practice. What is the best phone or email to reach you?
@RubySlays297
@RubySlays297 Ай бұрын
Does the 0.25% Finasteride topical form apply for women also?
@profLidiaRudnicka
@profLidiaRudnicka 22 күн бұрын
It is not approved in women.
@sabaakram1426
@sabaakram1426 Жыл бұрын
Mam i have androgentic alopcia high testosterone what should i do
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
I suggest to analyse with the endocrinologist the reason for increased testosteron and whether it requires endocrinologic treatment
@AsifGoldy2289
@AsifGoldy2289 Жыл бұрын
Mam can i use dutasteride 0.5 mg for hai because i am very sad for my hair loss
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Every diagnosis and treatment decision has to be made by your dermatologist. Every situation is different
@hcyxtvtxyck1419
@hcyxtvtxyck1419 Жыл бұрын
Szanowna Pani Profesor. Po pierwsze chce przekazać Pani wyrazy uznania, podziwiam ludzi takich jak Pani-którzy cały czas rozwijają naukę i siebie, są zawsze głodni wiedzy! Mam takie pytanie, czy poleca Pani Profesor jakiego dermatologa w Krakowie-najlepiej takiego szczególnie zainteresowanego chorobami włosów i skory głowy-dokładnie mam AGA. Bardzo mi zależy żeby kierował się EBM. Może zna Pani takiego… będę bardzo wdzięczy za odpowiedz. Pozdrawiam i dziękuje Ps. To prawda że mezoterapia dutasterydem i osoczem ma swoje oparcie w EBM (w AGA)?
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Dziękuję bardzo. Dutasteryd doogniskowy ma pozytywne opinie wielu ekspertów, ale jest w minimalnym stopniu EBM. Przede wszystkim nie jest zarejestrowany jako lek, więc nie przeszedł niezbednych dla leków kontroli. Dlatego nie ma go w tym wideo. W Krakowie jest wielu doskonałych dermatologów i jestem pewna że wszyscy lub prawie wszyscy zajmują się AGA.
@dheerajverma2220
@dheerajverma2220 Жыл бұрын
Mam I have diffused thining,Doctor gave me dutasteride and it is not working
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
It depends on treatment time, dose, expectations, and the perception of efficacy. I suggest to consult the doctor about modifying the treatment.
@dheerajverma2220
@dheerajverma2220 Жыл бұрын
@@profLidiaRudnicka is dutasteride better than finasteride in terms of improving hair? I HAVE Sebbhoric dermatitis too
@franciscosimental4930
@franciscosimental4930 6 ай бұрын
Yo diría que la ginecomastia en hombres que toman finasterida es bastante frecuente. Los estudios dicen una cosa pero la realidad es otra.
@profLidiaRudnicka
@profLidiaRudnicka 6 ай бұрын
Are you a dermatologist or a urologist ? What is your experience?
@franciscosimental4930
@franciscosimental4930 6 ай бұрын
@@profLidiaRudnicka no doctora, pero tomo finasterida y tengo ginecomastia y a dos amigos mios les sucede igual. 🙂
@profLidiaRudnicka
@profLidiaRudnicka 6 ай бұрын
This is 3 persons. This is in my opinion not sufficient for statistical conclusions in a world where multiple millions of people are taking the drug….
@franciscosimental4930
@franciscosimental4930 6 ай бұрын
@@profLidiaRudnicka 🥲🥲🥲🥲
@myreviews4905
@myreviews4905 Жыл бұрын
I saw a video that states the since Dutasteride is over 500 Dalton it doesn't cross into the blood from the scalp if applied topically. But Finasteride is less than 500 Dalton and does cross. Even if both drugs causes and is systemically absorbed, it is still way less (> 10X) absorption than the oral forms correct? kzfaq.info/get/bejne/mclhgMV3qb6pZ3U.html
@profLidiaRudnicka
@profLidiaRudnicka 8 ай бұрын
Partly yes, but any skin changes (scraches, folliculitis etc) on the scalp, even minor, may alter the penetration
@amrammar740
@amrammar740 Жыл бұрын
Wow ❤ Very interesting, informative and to the point therapeutic pearls as usual, Thanks our dear professor But I have a question What is your experience regarding Intralesional dutasteride in AGA in the form of nesotherapy And topical spironolactone in AGA ( I have previous published study with good and significant results : Ammar AM, Elshahid AR, Abdel-Dayem HA, Mohamed AA, Elsaie ML. Dermoscopic evaluation of the efficacy of combination of topical spironolactone 5% and minoxidil 5% solutions in the treatment of androgenetic alopecia: A cross sectional-comparative study. J Cosmet Dermatol. 2022 Aug 29. doi: 10.1111/jocd.15328. Epub ahead of print. PMID: 36039391.) Thanks in advance ❤
@profLidiaRudnicka
@profLidiaRudnicka Жыл бұрын
Thank you, it is always such a pleasure to have your feedback! Intralesional dutasteride has good opinions and some literature data , but it is not approved as a drug with all consequences, so I prefer to wait for a more validated product. Regarding spironolactone - you are the master, so I can only repeat after you "oth spironolactone as a 5% topical solution and minoxidil as a 5% topical solution might be used safely in a twice-daily dosage to treat AGA". 💕
@amrammar740
@amrammar740 Жыл бұрын
@@profLidiaRudnicka It is a great honor for me dear professor and mentor, thanks you for your kind words and the continuous support, god bless you ❤️ ❤️
Should You Take Finasteride or Dutasteride for Hair Loss?
15:33
Dr. Kopelman
Рет қаралды 2,6 М.
SharmDerma 2020. Alopecia areata - trichoscopy and therapy
25:03
prof. Lidia Rudnicka
Рет қаралды 7 М.
路飞被小孩吓到了#海贼王#路飞
00:41
路飞与唐舞桐
Рет қаралды 67 МЛН
Дарю Самокат Скейтеру !
00:42
Vlad Samokatchik
Рет қаралды 3,6 МЛН
I CAN’T BELIEVE I LOST 😱
00:46
Topper Guild
Рет қаралды 109 МЛН
Finasteride and Dutasteride for Male Pattern Hair Loss
13:28
The Hair Loss Show
Рет қаралды 188 М.
Topical Finasteride: Same Results, No Side Effects?
17:43
Perfect Hair Health
Рет қаралды 162 М.
How to Treat Androgenic Alopecia in Females
12:26
Dr. Kate Lyzenga-Dean
Рет қаралды 8 М.
The 5 trichoscopy features of androgenetic alopecia
8:54
prof. Lidia Rudnicka
Рет қаралды 24 М.
Frontal Fibrosing Alopecia
6:52
prof. Lidia Rudnicka
Рет қаралды 4,7 М.
Causes of hair loss and trichoscopy for medical students and patients
16:37
prof. Lidia Rudnicka
Рет қаралды 7 М.
Side Effects of Finasteride | The Hair Loss Show
15:21
The Hair Loss Show
Рет қаралды 1,1 МЛН
What's New In the Treatment of Female Hair Loss Heading into 2023
48:44
Basic trichoscopy structures (2022)
11:47
prof. Lidia Rudnicka
Рет қаралды 4 М.