today we are going to discuss about Fluoroquinolones
classification of fluoroquinolones , ADR of Fluoroquinolones , spectrum of Fluoroquinolones , contraindication of Fluoroquinolones , uses of Fluoroquinolones ,
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FLUOROQUINOLONES
These are quinolone antimicrobials having one or more fluorine substitutions.
The ‘first generation’ fluoroquinolones (FQs) introduced in 1980s have one fluoro substitution
Classification
First generation fluoroquinolones
Norfloxacin, Ofloxacin ,Ciprofloxacin ,Pefloxacin
Second generation fluoroquinolones
Levofloxacin ,Moxifloxacin ,Lomefloxacin, Gemifloxacin ,Prulifloxacin
contraindication
1. Pregnancy 2. age below 18 year 3. theophyllin toxicity
4.arrythmia 5.calcium , iron prepration  reduce absorption
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