Glioblastoma: Working to Turn the Tide on This Deadly Brain Cancer

Рет қаралды 28,146

4 жыл бұрын

Researchers at the University of Michigan Rogel Cancer Center are working to better understand and treat brain cancer.
One of the most pernicious types of brain cancer is glioblastoma, which claimed the lives of senators John McCain and Ted Kennedy. Even with the best current treatments, patients who live more than a year and half after diagnosis are counted among the lucky ones.
Several research labs at the Rogel Cancer Center are actively pursuing new efforts to extend and to improve the lives of patients with this deadly disease.
The lab of Maria G. Castro, Ph.D. and Pedro R. Lowenstein, M.D., Ph.D. - both professors of neurosurgery and cell and developmental biology at Michigan Medicine - is optimistic about initial results from a clinical trial stemming from their laboratory research, which uses gene therapy to attack tumors while also enhancing the immune system’s ability to fight them.
Meanwhile the lab of Daniel Wahl, M.D., Ph.D., an assistant professor of radiation oncology, is interested in how abnormal metabolism in these tumors makes them resistant to treatment with radiation. The lab is exploring different treatment combinations to overcome this resistance.
Related Content:
Glioblastoma 101: Michigan Neurosurgeon Explains the ‘Dreaded’ Diagnosis: michmed.org/ngn9p
Approach Could Help in Treating Glioblastoma, Other Rare Cancers: michmed.org/ExDoR
Immunotherapy, Gene Therapy Combination Shows Promise Against Glioblastoma: michmed.org/39z8G
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Learn more about the Rogel Cancer Center at Michigan Medicine here: www.rogelcancercenter.org/
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#Glioblastoma #Cancer #RogelCancerCenter #MichiganMedicine #Science #Research #Health #Medicine #Healthcare #Medical #Oncology #CancerTreatment #Genetics #RadiationOncology

Пікірлер: 163

@margon6087 4 жыл бұрын

My dad was diagnosed with glioblastoma grade 4 march 3,2020....it is so hard to see a love one go thru this..I'm praying that he beats the odds and lives a long life. Hope is all we got............

@bhaveshvaghela4338 4 жыл бұрын

My dad brin cansar G m but now 2 surgery stag 4 now good but chemotherapy dogs Everyday 1weekend

@AliHamza-wl5pn 4 жыл бұрын

Bhavesh Vaghela plz can you give me your email or WhatsApp. I need to ask some questions. my uncles diagnosed GBM 1 month ago. We had surgery. Now need to start radiotherapy and chemotherapy

@beninboy9226 4 жыл бұрын

Good news.my name is Caleb clark from maryland and i'm here to share good news with y'll. The era of no cure for Hiv is gone as it is curable in this era.I was diagnosed of this few years ago as it became unknown to me my girlfriend had it while we were dating.she only made it known to my friend after we broke up.hearing the news,i almost gave up and i have searched the cure but no way until a friend told me about doctor mercy who has the cure.I contacted him and i am free after using his medication.if you're there and have lost hope,congratulations as your hour of liberty has come.here are his contact drharrymercy@gmail.com,whatsapp +2348141659546. He can also cure cancer, diabetes, genital herpes, Goloria siphilis HAVE A GREAT DAY

@michellemichelle5202 3 жыл бұрын

Ali Hamza You should look into Panacur c and cutting out sugar. And something so the Panacur doesn’t destroy his liver. kzfaq.info/get/bejne/qaiGp9an0Mm4eX0.html

@AliHamza-wl5pn 3 жыл бұрын

Michelle Michelle thanks you. But my uncle died 1 month ago. 19th July 2020

@connieklein4401 4 жыл бұрын

Lost my husband of 50 yrs. to glioblastoma. Please pray they find a cure for this cruel disease! I miss him so!

@InfectedChris 3 жыл бұрын

This woman lost her husband and you're here trying to con them with your snake oil garbage!

@biasedjedi4353 3 жыл бұрын

@@InfectedChris Scammers are disgusting.

@InfectedChris 3 жыл бұрын

I am on immunotherapy currently. 4 plus years so far! There are long term survivors and don't give up!

@phern4965 3 жыл бұрын

Hi I’m happy to hear your going on 4+ years ! Stay strong and happy as hard as it gets. Sending my prayers.

@InfectedChris 3 жыл бұрын

@@phern4965 Thank you so much!

@OffiicialSteff 3 жыл бұрын

@@InfectedChris hey chris! Im glaf you are doing well and i wanted to tell you please never lose hope! My dad has this and he has had it since 1999 and he is still fighting today!:) latest news was that his treatment is working:) Just have hope! I wish you the best

@InfectedChris 3 жыл бұрын

@@OffiicialSteff Thank you! 21 years is an inspiration to me and I'm hoping I can achieve that too. A positive attitude plays such a huge role in outcomes. There are peer-reviewed studies showing as much. It's just one of the reasons I started a podcast for people like us who have been affected by this disease. Our medical knowledge is growing and new potential treatments are always in development. Thank you so much for the kind words!

@devanshshrivastava5070 3 жыл бұрын

This comment which give me relief so much

@jackierockers3552 Жыл бұрын

Praying about this! My sister was diagnosed with this and due to it's location it is inoperable. Praying for a miracle to have my sister longer. Her time is limited. Praying for all

@adithyahk 4 жыл бұрын

My mom was diagnosed in may 2019 and passed away in August 2019. I hope they find a cure for this tumour in the near future

@curiousgeorge6921 4 жыл бұрын

Did she have chemotherapy or radiation?

@adithyahk 4 жыл бұрын

The doc tried craniotomy and did not go ahead as he said tumor was inoperable. He suggested only conventional radiation and told us not go with chemo according to him chemo was waste of money. A cancer survivor in the family adamantly opposed radiation. But I was keen to go ahead with whatever I can before we came to a firm decision she left us.

@curiousgeorge6921 4 жыл бұрын

@@adithyahk so she died in 4 months with no treatment right?

@adithyahk 4 жыл бұрын

@@curiousgeorge6921 she was DX very late and passed away 86days after diagnosis she could have been given some more time the Neurosurgeon didn't believe in chemo where in the rest of the World follows Temozolomide as a standard therapy it's very strange for a doctor to say chemo was waste of money she was given dexamethasone abs levipil I sought second opinion but rest of the family was against that I was the only care giver and it was overwhelming for me emotionally mentally and physically .it was a rapid decline in her health condition I wanted go ahead with radiation but I couldn't because several reasons

@curiousgeorge6921 4 жыл бұрын

@@adithyahk the doctor was a good one actually, others would take your money and torture her with chemo for no reason

@umichrna 4 жыл бұрын

Congratulations UM Rogel Cancer Center team!

@citrixman 3 жыл бұрын

Press on and blessings to you !

@ulyssesbaldomere8346 2 жыл бұрын

Just lost my favorite and closest Uncle from GBM. It was hard to see a loved one go through this. There is still so much to learn and study. R.I.P. Uncle

@sselemaNrM 3 жыл бұрын

We need to increase funding for brain cancer research. The sooner we do, the faster we can find a treatment or cure with a significantly better quality of life and lifespan.

@lizslilcorneroftheinstitution 4 жыл бұрын

This is a monster that needs to be destroyed. My mom was given a dual pathology diagnosis of GBM and oligodendroglioma. From the date of her first symptom until her last breath took exactly 8 months, to the day. The speed and aggression with which this cancer destroys is hard to comprehend! She had surgery, radiation, chemotherapy and temodar. This may sound odd but before I take my last breath, I want to know what causes this cancer. Every specialist my mom was seen by all agreed that her cancer was caught much much earlier than normal. Yet nothing made a positive impact. Trying to understand the cause is like the biggest, or highest priority of things on my bucket list. It’s already odd to me that my extended family, on both maternal and paternal sides, seem to have a strangely high rate of illnesses involving the brain. Trying to wrap my head around the cause is my own personal mission. For anyone who has GBM or has a loved one with GBM, I truly hope the outcome for your situation is better than what I witnessed. Regardless, enjoy every minute you can. Don’t allow yourself to get in a position where you look back with guilt or regret. Take every opportunity to remind that family member how much you care for them!

@chandrikachandrasekharan9025 3 жыл бұрын

I lost my father 7 years back due to this horrible tumour.

@vanessagusman5047 2 жыл бұрын

My dad has had the blessing of two surgeries to remove the tumors, and radiation/ avastin infusions. After his last surgery in June he had a stroke . Now he’s on all sorts of meds and hallucinating/ aggressive- list goes on . I too try and research and would like to know the cause and cure . Hope they come out with one soon . 🥺

@alvincruz3116 2 жыл бұрын

MY NEPHEW HAS BRAIN TUMOR HES ONLY 10 YEARS OLD..SAD TO SEE HIM STRUGGLE ON YOUNG AGE HOPE SOME DOCTOR READ THIS AND HELP US, GOD BLESS US ALL

@nickkarasch 3 жыл бұрын

I have AA3 in the left-most part of my temporal lobe discovered over four years ago when I was 28. Some of us that don't go fast slowly have our brain degrading while always expecting death to be a few years away young. I'm hoping something like this makes it faster than 20-40 years from now before it is too late for me and so many others. Thank you for all of the work you are doing. It will happen someday and it keeps feeling closer and closer.

@jaredleto3650 3 жыл бұрын

i know of a doctor who can help you get rid of it permanently

@chattent13 3 жыл бұрын

I pray for the cure everyday.........

@valeriemason9615 2 жыл бұрын

I lost my Aunt on March 18 2021 to glioblastoma. I am following clinical trials, with the hope that they find an effective treatment and prevention for this horrible cancer.My hope is that I live to see this. My sympathies to all who have lost loved ones to this cancer.

@smitawagh2376 2 жыл бұрын

My brother recently passed away with this GBM 4 Brain cancer,.. he was diagnosed month before demise.. shocked when doctor told no cure , just treatment for survival, but rate is just 4 percent.. keep going on research, All the Best

@vicranger6876 4 жыл бұрын

Dr Linda Liau , a foremost neurosurgeon , UCLA has been studying glioblastoma for her entire professional life and is currently engaged in a clinical researching DCVax-L which has been very effective in extending life for those patients. Some GBM patients are still alive after 10 yrs. The process requires tumor samples from the patient & frozen under a specific protocol, to create a vaccine derived from the tumor cells. It is currently approved for compassionate use in the UK as clinical continues. The clinical is expected to finish very shortly. Known data has been very encouraging.

@joselara371 2 жыл бұрын

Is it a cure or a prolonged life treatment

@namehhalaseh8277 2 жыл бұрын

Any updates

@phern4965 3 жыл бұрын

My mother who is 52 was diagnosed last year and let me tell you, It is the worse feeling to watch a loved one die from this disease. It was quick and her symptoms are worse and worse every day. Hospice nurse said she may only have 1 week. Let’s all say a prayer to heal those and those families affected by this disease.

@christywilson799 3 жыл бұрын

Hi! How did it go? My mom just got diagnosed and they told her 6 months without treatment or 12 months with it but she just seems worse. Prayers to your mother!

@ligmaballs8876 3 жыл бұрын

@@christywilson799 is your mother still here? Sending prayers

@ligmaballs8876 3 жыл бұрын

Praying for you man, I pray your mother makes it from 52 years to 100 years

@ololubebenitah6134 2 жыл бұрын

What are all the symptoms she showed

@teddyli4763 3 жыл бұрын

Giving any beings cancer is so horrendous may god have mercy on these peoples souls

@BrightFallsTV 4 жыл бұрын

Praying for everyone who has lost a close person!, fighting for a person life! or himself going through therapies! YOU ARE ALL STRONG PEOPLE! Don't lose hope & especially don't Lose HOPE! spend time with those who around you! LOVE IS WHAT MATTERS!

@iLOVEpalestineFOREVER 4 жыл бұрын

Holy shit if this works in humans it'll be historic

@unlimitedousman1344 4 жыл бұрын

It was amazing but still has few views

@kellyfirkins8864 3 жыл бұрын

What do patients need to do to preserve eligibility to get in a trial? Will standard chemo and radiation algorithms exclude people you want for Phase 3?

@arielflores6260 3 жыл бұрын

Help my wife is 28 years old she has this and it so hard for her .

@rayruckus4446 3 жыл бұрын

Ie got it. It truly sucks. It's made me Hemiperadic Not fun. I plan on leaving my body to science so they can do something with it.

@rintahazra627 2 жыл бұрын

I lost my father 3 months ago in this disease. .he was fighting a lot. .but we can't do anything to alive him..I pray that someone may discover the diagnosis of globustroma

@_captainmagic 2 жыл бұрын

This cancer killed my mom, we didn't even catch it in time to try treatment. It's been almost 3 years, I miss her.

@ololubebenitah6134 2 жыл бұрын

What are the symptoms she went through

4 жыл бұрын

My brother passed today from it. Stage 4. Diagnosed june 2019 and passed may 20, 2020 at 12:05 am. 34 yrs old. My baby brother.this disease sucks and took the most important thing in the world to me.

@jamiemcallister8308 4 жыл бұрын

Sorry to hear that. My mum has it and is at the end of end of life stage she’s not eating and just sleeping now so she’ll no longer be with us shortly.

@AliHamza-wl5pn 4 жыл бұрын

Jamie McAllister plz can you give me your experience. My uncle diagnosed GBM month ago. How we can fight with gbm?

@AliHamza-wl5pn 4 жыл бұрын

RIP

@nareshs5403 4 жыл бұрын

@@AliHamza-wl5pn hey Jamie my mom has grade 4 GBM.is that curable...

@curiousgeorge6921 4 жыл бұрын

Sorry to hear that, i hope he has no kids who'd grow up without him

@chandrikachandrasekharan9025 3 жыл бұрын

I lost my father 7 years back due to this horrible tumour. I honestly wish those who are diagnosed have a better outcome than my father.

@jalayshah2532 2 жыл бұрын

My mom is currently detected with one

@jeannedoan7748 2 жыл бұрын

@@jalayshah2532 How is your Mom now? 🙏🙏

@jalayshah2532 2 жыл бұрын

@@jeannedoan7748 She passed away on 16th last month

@ololubebenitah6134 2 жыл бұрын

@@jalayshah2532 what are the symptoms she showed

@jalayshah2532 2 жыл бұрын

@@ololubebenitah6134 Behavior change, recent memory loss, imbalance, loss of control on motions, seizures, etc.

@jasoncombs664 3 жыл бұрын

How can I get in contact with anyone who can help. My brother has glioblastoma and is fighting for his life as we speak. Please who has the best treatment and clinical trials available.

@twinkledass1884 2 жыл бұрын

Jesus only can save your brother keep faith on god and pray my mother suffering from this cancer

@johnobrien4755 Жыл бұрын

2022. Plenty of work being done but unfortunately for me and many others there is no cure nor is there one imminent.

@brucedressel8873 2 жыл бұрын

To all of my fellow brothers and sisters battling this crazy cancer Please always remember this... And all things, whatsoever ye shall ask in prayer, believing, ye shall receive.Matthew 21 22 KJV

@ronevans3844 4 жыл бұрын

KAZIA company can cross the Brain Barrier , in U.S.

@lisaschuster686 2 жыл бұрын

A 50-year-old doctor has hopes that in 40 years, at the end of his career, there will be good treatment options? This was the least informative video and even the doctor is in denial.