Highest Yield Drugs for USMLE

Рет қаралды 332,212

7 жыл бұрын

SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

Пікірлер: 168

@DirtyMedicine 6 жыл бұрын

Correction: Red Man Syndrome is treated with anti-histamines.

@derrickcleland3181 5 жыл бұрын

Also, G6PD deficiencies have a negative Coombs test. You said they were positive in your vid, in regards to isoniazid.

@AznCoolDragon 5 жыл бұрын

For drug induced lupus, how about HIP Mums are Qute (for cute) when STONED on weed, lol

@doctorsmart936 5 жыл бұрын

Please...please...p450 mnemonic

@HT.100 5 жыл бұрын

And vancomycin

@restinginn9906 4 жыл бұрын

Correct, and SLOW INFUSION of vancomycin can prevent red man syndrome

@yesihavequestions5752 Жыл бұрын

Pnemonic for remembering Lupus Drugs, Harry Potter Themed: Defense against the dark arts teacher DR LUPUS walks into the headmaster office after his LUPUS transformation. he says "Hi, Im Pretty Much Quitting" --> Hydralazine, Isoniazid, Procainamide, Methyldopa, Quinidine" Thank you Dirty Med for an AMAZING vid!

@earlkoh216 23 күн бұрын

Hi, rearranging the mnmo to Dr lupus saying: Hi I'm probably quitting meth. (It's easier to remember when the sound is identical eg, meth- methyldopa, rather than just the letters

@Gymnopediea 6 жыл бұрын

You make this so much more interesting. Definitely donating!

@pyrexcookin 3 жыл бұрын

For TB Treatment I expanded your mnemonic to RIPPER ONGLOW, the extra P and R representing Pyridoxine and Rifabutin. Those two line up with the L and W, respectively, to represent L=Lessen isoniazid's side effect (pyridoxine is simply b6 so you coadminister with isoniazid to lessen that b6 deficiency) and W=Weakened liver/immunity (rifabutin is given instead of rifampin in patients taking CYP450 liver metabolism-altering drugs - especially high yield for HIV patients due to protease inhibitor usage).

@rayblade6383 5 жыл бұрын

Your videos are amazing... You have a knack for teaching. Brilliant, seriously brilliant!

@BK914 7 жыл бұрын

Also for agranulocytosis Thionamides like PTU for treating hyperthyroidism. Thats another HY.

@zakariyairfanullah4287 4 жыл бұрын

Hey man. Absolutely love your content and recommend it to everyone I know. You had a dope diabetes pharm video that I can’t seem to find anywhere. Really hope you could link me to it, or upload it again ASAP. Thanks!

@Reynosorex 4 жыл бұрын

To this KZfaqr and all the people with their helpful comments, I sincerely Thank You.

@DirtyMedicine 4 жыл бұрын

that's what this channel is all about.. a community for people to help each other learn more

@joethejo-ker9480 6 жыл бұрын

this channel needs wayyyyyy more attention God bless

@MA-fw8wg 5 жыл бұрын

could you make a part 2 for this video? It was very helpful!

@mominaafrede4335 7 жыл бұрын

wow! loved the video for step 1 pharm! which other videos of yours would you say are as high yield as this from your channel? thanks so much!!!

@deathkissgoodbye 6 жыл бұрын

Loop earrings = loop ototoxicity

@anniedatoo 6 жыл бұрын

I have my Step 1 in 15 days. I love your videos!!! Thank you!!! Keep making more!

@karataych0p 6 жыл бұрын

Hope you destroyed it!!!

@doctorevil6768 5 жыл бұрын

Omg I have mine in exactly 15 days, I’m sooo nervous

@joethejo-ker9480 5 жыл бұрын

Doctor evil How did you do ??

@abdulrahman-ji5ye 5 жыл бұрын

A HAJI DATOO any suggestions . I will be appearing in 2 months

@user-jp7sc2vb9w 5 жыл бұрын

A HAJI DATOO - how'd it go? Hope you aced it!

@catherweenie 7 жыл бұрын

Don't know how I ended up here but I'm a pharmacy student and wanted to say that this video is great! The mnemonics were useful too.

@isag4913 7 жыл бұрын

Thank you! Really helpful for a quick review.

@tejjoshi5250 6 жыл бұрын

Just an edit to the Class IC antiarrhythmics - they cause QRS prolongation but have no effect on the QT interval.

@caracara4478 6 жыл бұрын

hi! keep up the good work please make a video on antibiotics( mech, adv effects, indications, route and drugs of choice in various infections)

@matthewl.4269 3 жыл бұрын

Super helpful video! Also, I'd recognize a Philly accent anywhere...are you from Philly?

@billalahmed3719 5 жыл бұрын

Excellent video! You mentioned how Isoniazid can trigger G6PD deficiency hemolysis, and you also mentioned that it might manifest with a positive coombs test, but I don't know if it would have a positive coombs test. My understanding is that isoniazid is causing oxidative stress that the G6PD-deficient RBC cannot handle (because it lacks glutathione) and will therefore hemolyse. This is different than a hemolytic anemia where there are antibodies against some antigen on the RBC (it is in this case where you'd get a positive coombs test). Let me know your thoughts!

@raquelrodrigues6198 4 жыл бұрын

Agree!

@mazeed9526 4 жыл бұрын

no matter what first thing I do is pressing like button on your video n then start watching cuz I know its gonna be a great video .......

@cr1538 5 жыл бұрын

This is amazing!! Thank you!!

@davidszandzik9784 7 жыл бұрын

"Quin Proclaimed he IS stoned on hydra meth"

@parvinmustafayev2004 7 жыл бұрын

Great Job! As well Your english is very understandable! Please keep it up !!!!

@dr.poornaprajna Ай бұрын

7 years down the line... yeah you are still helpful! Thanks dirty!

@hageraltaher281 3 жыл бұрын

You are amazing, thank you so much 💗

@redache467 3 жыл бұрын

Red man syndrome is also rarely caused by morphine. Both morphine and vancomycin do that by IgE-independent mast cell degranulation.

@stephanquintin7013 Жыл бұрын

Lupus inducing drug pneumonic: "Lupus at the IMP HQ" as in the "imp(demon fairy) head quarters" I just remember the imps from ruinscape. May be too niche but helps me.

@ast1848 7 жыл бұрын

Great vid, liked the fb page as well!

@DirtyMedicine 7 жыл бұрын

Thanks, Ash!

@drkrunalortho-knowledge 6 жыл бұрын

DirtyUSMLE For drug induced lupus Think some Quin is taking drug and going to SLEep Quins HIP My Dickinson Quinine Hydralazine Isoniazide Procainamide Methyl dopamine Sickle is like stone so anti Histone abody

@WasabiSniffer 5 күн бұрын

A bunch of started to link together for me. Thanks!

@xeraxesmylio940 2 жыл бұрын

@7:42: Hydration Quietly Processes Ice into Meth, causing LUPUS May not be chemically true, but it helped me remember the agents of drug-induced lupus.

@syrono 7 жыл бұрын

Thank you Very much sir, helped alot

@nikakovach3991 4 ай бұрын

Thank you! Could you make a video about restriction fragment length polymorphism analysis? Pls!

@annakoren1626 Жыл бұрын

Isoniazid causes the b6 deficiency which is a pathway needed for formation of protoporphyrin and that leads to sideroblastic anemia.

@path-etic 6 жыл бұрын

small correction: i believe vancomycin's red man syndrome is best managed with an antihistamine, not an NSAID. (But please lemme know if I'm wrong about this) thanks for all you do!

@MRSAXOBEAT1992 6 жыл бұрын

Yeah, I remember studying that as well, that for Vancomycin you give antihistamines, and for Niacin induced flushing you give NSAID's cause its Prostaglandin mediated

@onuhcynthia3758 2 жыл бұрын

@@MRSAXOBEAT1992 yes you are right, aspirin precisely is administered with Niacin.

@jillianjuson1289 2 жыл бұрын

Antihistamine specifically diphenhydramine?

@niceangel9779 3 жыл бұрын

du bist der Hammer buddy 👍👍👍💜

@MA-fw8wg 5 жыл бұрын

AMAZING!!!!!! thanks

@wafaimran4027 2 жыл бұрын

writing articles and publishing them in a journal (is that what's included in research work please advise) is that a valuable asset to our cv for residency in highly competitive specialties? Please advise.

@OneGirlRecipes 3 жыл бұрын

Is this still good to go for 2020? I'm taking step in a month lol

@kristinsyed6875 6 жыл бұрын

Great review! for redman syndrome give anti-histamines.

@pumpkinheadjrb 2 жыл бұрын

Need a slide on CYP450 inducers and inhibitors! I get a question on that every 100 questions.

@athulya6613 6 жыл бұрын

Can you prepare a video on anti cancer drugs. I find it very difficult to recollect

@Purpleporkypine 3 жыл бұрын

Any change for updated version? :)

@thepacemaker8165 4 жыл бұрын

Great work!!

@Giantcrabz 13 күн бұрын

im a pharmacist and i take celebrex for years, and I didn't think of it for gastric ulcers. Brilliant. My brain no good after night shift 😅

@WhyNot-si4pj Жыл бұрын

9:43 Class Ic antiarrhythmic drugs do NOT block K+ channels or prolong the cardiac action potential along with the QT interval .

@t.w.8174 5 жыл бұрын

great video. thank you.

@ericnguyen7927 4 жыл бұрын

Don't forget about Cyclosporine/Tacrolimus with nephrotoxicity!

@nibajuste3311 2 жыл бұрын

macrolides prolong the QT interval except azithromycin

@WhyNot-si4pj Жыл бұрын

10:19 Quinidine is more common to cause drug induced thrombocytopenia than hemolysis ; while DAPSONE causes hemolysis in G6PD patients

@ryankelly8077 4 жыл бұрын

You’re the man

@FG-ng1cy 6 жыл бұрын

Thank u.could u make video regarding psychiatric drugs.thank u

@costia321 6 жыл бұрын

what happened to your other pharmacology videos?

@emmanuelmeribole4104 Жыл бұрын

Thank you so much for these videos … I just passed my step 1

@Lana-vh5kr Жыл бұрын

Congrats, Which other videos do you recommend watching?

@emmanuelmeribole4104 Жыл бұрын

@@Lana-vh5kr I also used randy Neil to brush up biostats… and the review portion of FA. But dirty medicine helped me most.. Even the biohacks for 260 videos

@Lana-vh5kr Жыл бұрын

Did you watch all of dirty medicine videos? Also can I ask you about what you thought about the exam, what didnyou feel they concentrated on the most?

@emmanuelmeribole4104 Жыл бұрын

@@Lana-vh5kr I watched the topics I felt like I needed clarification on … because I was pressed for time. Every exam is different, mine was focused on pathology and drugs of abuse with about 2 questions on biostats per block

@Lana-vh5kr Жыл бұрын

Can I also ask how much you scored in NBMEs? I'm sorry for all the questions, I'm taking my exam soon and I'm so stressed

@tawfeekb24 Жыл бұрын

thank you king

@sarahc.1998 6 жыл бұрын

Extremely helpful. I need help in biochemistry as well 😰😭😥

@Rena0530 2 жыл бұрын

First Aid 2021 has gout as adverse effect of Loop Diuretics, but it makes sense to me what you're saying - gout is an adverse effect of Thiazides because they decrease Ca excretion. Could you please clarify if gout shows up with Loop Diuretics? I see that you don't have gout as an adverse effect of Loop Diuretics here.

@alaads5944 Жыл бұрын

gout attacks are side effects of both drugs, as they both compete for secretion with uric acid , leading to it's accumulation -----> increased gout attacks

@ginidosi1 2 жыл бұрын

my mnemonic for Rx induced SLE --> "stoned on HIP QUIck METH stoned= antihistone abs H= Hyydralazine I=Isonaizid P=Procainamide QUI= Quinidine METH= Methyldopa Hope this helps someone :)

@jondharwell Жыл бұрын

Just did!

@asdbabel9792 7 жыл бұрын

excellent

@pinokosthewife 5 жыл бұрын

Another good mnemonic: HMLN sounds like "pied piper of HMLN" (HaMeLiN?). It works, moms, pied pipers...

@wasek152 6 жыл бұрын

class 1c causes QT or QRS prolongation, does it act on k channel?

@ariannealexander9175 6 жыл бұрын

class IC is a Na+ channel blocker

@ravisinha6776 5 жыл бұрын

Yah Class 1C does NOT prolong QT As far as I remember. Out of the Anti-arrthymics, the ones that cause prolonged QT are Class 1A, and Class 3 ( which are K+ channel blockers ) with the EXCEPTION OF AMIODARONE. Class 1C is all about state dependence meaning when your heart rate starts to go up like during exercise, that's when Class 1C works - so it's state dependence and this will lead to a DELAYED depolarization at higher heart rates, but wont' do anything for the potassium channels in phase 3. And so it has strong SODIUM CHANNEL BLOCKAGE.

@pavelpavel6822 3 жыл бұрын

Thanks

@Sasukeloverxxx 3 жыл бұрын

Literally JUST had a UW question with mesna

@jeremias3461 6 жыл бұрын

Can anyone confirm if 1c arrhythmics prolong QT? I thought it was just 1a

@muhammadsiddiqui8720 5 жыл бұрын

I would like a confirmation as well. Class Ic drugs are pure Na+ channel blockers so they would cause QRS prolongation, not QT prolongation.

@hira5108 5 жыл бұрын

1A significantly prolongs QT whereas 1C slights prolongs it mainly due to QRS widening (reference: uworld)

@onuhcynthia3758 2 жыл бұрын

@@muhammadsiddiqui8720 it’s actually a QT prolongation rather than a QRS prolongation. Class 1a and 1c does that.

@onuhcynthia3758 2 жыл бұрын

Sorry I made a mistake, it’s class 1a and class 3 that prolong QT, class 1c doesn’t.

@monika246 5 жыл бұрын

Your all the videos are high yield!!

@lumbarspine4637 7 жыл бұрын

Super

@josephmeade7055 5 жыл бұрын

Do we use Agatroban or Protamine Sulfate for heparin induced thrombocytopenia?

@FlawlessNJ 5 жыл бұрын

Agatroban or lipuridin for HIT, protamine sulfate is used in heparin OVERDOSE to reverse its effect NOT in HIT. Good luck!

@ravisinha6776 5 жыл бұрын

@@FlawlessNJ I can totally see them asking this as a question as it might confuse students while in a TIMED mode

@monika246 4 жыл бұрын

Thiazides causes hypercalcemia but it is also used in hypercalciuria right?explain please

@DirtyMedicine 4 жыл бұрын

Thiazides cause hypercalcEMIA (emia = blood, so "too much calcium in the blood). HypercalciURIA (uria = urine, so "too much calcium in the urine) is a different entity entirely. The mechanism is inhibition of Na/Cl co-porter, which disrupts the membrane potential preventing Calcium from being excreted into the urine (so Calcium builds up in the blood).

@rheyanabranch 3 жыл бұрын

Drug induced lupus: I think of the lupus wolf. "My Happy Pup - Quit it"

@kkalright 7 жыл бұрын

From what i learned Loop diuretics can also preceipitate gout

@DirtyMedicine 7 жыл бұрын

Not on boards they don't

@danyelbaker6109 7 жыл бұрын

hahahahahahahaha!!!

@FrazAhmadMD 7 жыл бұрын

DirtyUSMLE Lol

@MidnightMimosa1 3 жыл бұрын

+ to the color drugs -> Yellow vision from digoxin toxicity

@HusseinBerjaoui 4 жыл бұрын

2019 and still as relevant

@pranuthiratna4722 3 жыл бұрын

Hussein Berjaoui 2020 and still as relevant 🐾

@HusseinBerjaoui 3 жыл бұрын

@@pranuthiratna4722 Step 2 soon and maybe this is a sign that it's still as relevant haha

@Chelsea-gs7qj 3 жыл бұрын

2021 and still relevant

@Time2ChooseYou 2 жыл бұрын

Keeping this comment alive in 2022~ :D

@MostafaDawa 8 ай бұрын

2023 and still relevant

@KnightMD 2 жыл бұрын

E-thambutol.....E-ye iNh..... Neuro Pyrazinamide... Gout (PG)

@yevchornenkyy4805 7 жыл бұрын

Do you have print out books or is your information available in text format?

@paulrodriguez168 Жыл бұрын

The two O's in oto-toxicity look like loops => loop diuretics

@makeupjunkie5066 4 жыл бұрын

I like "RIPE ONGO" mnemonic

@newmanlord7130 Жыл бұрын

Then USLME is conducted chronic,prior.

@Mo-ez3hs 3 жыл бұрын

all love

@Nita99999 6 жыл бұрын

Vancomycin causes ototoxicity, quinidine causes cinchonism

@zho0616 7 жыл бұрын

10:49..isoniazid does ton of shit LOL

@JMat1986 6 жыл бұрын

"DIRTY" USMLE ;)

@willford455 5 жыл бұрын

lmaooo!!!

@saeedabdulaziz5318 4 жыл бұрын

For drug induce lupus SHIPP My Queen ( sulfonamide, Hydralazine, Isoniazid, Proconamide, Phenytoin, Methyldopa, quinidine)

@tkhan2392 6 жыл бұрын

Please make a video on Chemotherapeutic drugs and their cancer/disease indication

@DirtyMedicine 6 жыл бұрын

low yield for boards

@tkhan2392 6 жыл бұрын

oh..ok! Thanks for the info

@junaidmushtaq9421 4 жыл бұрын

very HY , IN last medical exam 5-6 questions appear from these HY points,,

@Rena0530 2 жыл бұрын

Looks like Quinidine no longer is contraindicated with G6PD deficiency

@irfansonu2020 4 жыл бұрын

Which book should I read for pharmacology

@AhmedMohamed-zi9mn 4 жыл бұрын

Lippicoat pharmacology

@zuhairyassin505 4 жыл бұрын

tripathi you can never go wrong with it has the pathophysiology and medical pharmacology

@mourilshah2054 4 жыл бұрын

For Anti Tb drugs Rifampin - Red-orange secretions First letters Isoniazid - causes hepatitis increases ALT and AST and B6 is an important cofactor for those so B6 is deficient and leads to neurological symptoms along with sideroblastic anemia Pyrazinamide - Weak acid , so competes with gout for tubular secretion leading to hyperuricemia worsening Gout E (ye)thambutol - optic neuritis