Absolutely awesome video. I love your teaching style.
@friendlyneighborhoodimmuno71923 жыл бұрын
Thanks so much for the support! I’ll have new videos later this week.
@gozorak3 жыл бұрын
I really wish that I had access to this video last July when I was in the hospital for 10 day(4 of which were in the ICU) because I got hit by ITP out of the blue and had a platelet level of 2(2,000). It would have made things so much more clear than not understanding the multiple hematologists attempting to explain to me my new condition. Job well done on a basic primer.
@friendlyneighborhoodimmuno71923 жыл бұрын
I am sorry to hear you have ITP, but I am glad that I could help explain things clearly. I hope your ITP is under control and you are feeling better. Take care!
@gozorak3 жыл бұрын
@@friendlyneighborhoodimmuno7192 Actually I have been stable at around 100,000 for nearly 6 months after 4 rounds of Rituximab last July/August and weekly Nplate injections until the end of last November. Honestly I dont even think about it anymore. My body doesnt feel the same but maybe thats age...and I DID get the Covid Vaccine(Pfizer) with my second dose a month and a half ago with no negative reactions...note to fellow ITP'ers
@friendlyneighborhoodimmuno71923 жыл бұрын
@@gozorak that is such encouraging news! Congrats and thanks for sharing!
@demonshelby13113 жыл бұрын
They diagnosed me at my 12 week pregnancy check and I was in hospital for most of the pregnancy. They took my spleen out and now I'm in the most vulnerable group. I'm pleased to hear that you are doing well
@gozorak3 жыл бұрын
@@demonshelby1311 Im so sorry to hear that. How long ago was your diagnosis and have you platelet levels remained stable after your spleen removal?
@GaryJames8643 жыл бұрын
I also found a personal application. Many years ago, because of an unexpected medication interaction between a newly prescribed med and a common OTC, I had drug induced thrombocytopenia. I got a panic levels, emergency call from the lab, after I had the blood draw and was told to stop all meds and go directly to my MD or the emergency department. Thrombocytopenia is usually not a panic situation, but in rare cases it can be life threatening. Thank the Lord for conscientious lab technicians and lab directors. And doctors that take unexpected bruising seriously.
@friendlyneighborhoodimmuno71923 жыл бұрын
Wow that's a scary experience. Glad the lab techs were on top of it. My mom was a med tech at a hospital for many years.
@kr47032 жыл бұрын
I just told my wife I could watch these videos all day Informative and making me recall my college Anatomy and Physiology classes ... If I have to Change my current career, I will head back for immunology ... Thank you for sharing this. Sent this to my son who was diagnosed with ITP and almost had his spleen removed. He asked his doctor to have his vitamin D levels checked ... Doctor laughed at his request ... Doc had to eat crow when she called him up saying you need to go to the pharmacy and pick up a prescription for 50K Vitamin D Rx ... His ITP seemingly went into remission ... Have a great day and Thank you for sharing your knowledge. Keep it coming!
@friendlyneighborhoodimmuno71922 жыл бұрын
Oh that's great news! Vitamin D is very important for the immune system. Glad your son's ITP is in remission.
@francesfisher9653 Жыл бұрын
So happy I found your video. Blood tests revealed 95 platelet count and I'm scheduled to see hematologist. Appreciate your explanation and your tone of voice. Thanks.
@knoxjulesc2 жыл бұрын
I’ve been really enjoying watching your videos. So glad to have found your channel! Hearing you mention you are a d&d nerd made me smile and like you even more. :) Thank you for making science easier to understand.
@friendlyneighborhoodimmuno71922 жыл бұрын
Thank you so much!
@bluewave71203 ай бұрын
I just subscribed to your channel Love your kind thoughts and warm smile
@belenjimenez91288 ай бұрын
I recently was diagnosed with iTP, thank you. This is the best video I’ve seen ❤
@michelandre43252 жыл бұрын
Well done - the epitome of a succinctly well presented presentation with simple basic explanation for everyone. Thank you
@friendlyneighborhoodimmuno71922 жыл бұрын
Glad it was helpful!
@sarahpolsinelli566 Жыл бұрын
You have such a great voice! Great information - thank you. My 11 yr old son was diagnosed with acute ITP on new years. His platelets were 15 10*9/L. He received IVIG. Due to vomiting/headaches from tx he was in the hospital for 4 days. His platelets on recent blood test were 460… too high now. Has anyone experienced this? Is there a chance that he won’t relapse? He only had a cold prior to this happening. He did have one dose of Pfizer, and has had covid 4 times…
@GaryJames8643 жыл бұрын
Incredible class on thrombocytopenia. Good review of nearly 40 yo Anatomy & Physiology, and Pathophysiology courses for me. Your videos in general are very informative, better than almost all similar on KZfaq videos by MDs and wannabes. You are performing a vital service. You failed to get into the specifics of DIC, And why the usual standard of care for thrombocytopenia is contraindicated for many cases of thrombocytopenia that is sometimes a very rare AE of the J&J/Jansen vaccine and in DIC. I guess it might be confusing to introduce at this basic level, because the mechanism is counterintuitive, But it does help explain why the initial cases were detected in women by an alert Ob-Gyn, as peripartum DIC is always "on their radar".
@friendlyneighborhoodimmuno71923 жыл бұрын
Thank you for the compliments! Yes you bring up a good point about DIC, and it could explain why initial cases were detected in women. Some birth control + smoking can increase clot risk in young women too.
@Chipncrem Жыл бұрын
Might be a bit late, but I had thrombocytopenia as a result of the Covid vaccine,a day after the first jab. Hospital team saved my life with prednisone, yet my body has never recovered back to a normal life, with symptoms very very similar to long Covid. Reported to the ministry of health, but never received any support.
@snipernbolt13 жыл бұрын
This is great information. I've recently come down with ITP but they haven't figured out why yet. I haven't gotten any jab and have been healthy all my adult life.
@friendlyneighborhoodimmuno71923 жыл бұрын
Sorry to hear that you have ITP. Sometimes ITP can be genetic but most likely it’s due to a viral infection. When your body fights off certain viruses the protein your B cells react to is similar to a protein in platelets. Type I diabetes is similar in pathology. The Virus looks like beta pancreatic cells or it infects pancreatic cells and in the immune carnage the B cells accidentally make antibodies to the cells of the pancreas. I hope your case is mild and manageable! Take care! www.mayoclinic.org/diseases-conditions/idiopathic-thrombocytopenic-purpura/symptoms-causes/syc-20352325
@pedropitoyko64653 жыл бұрын
Wow, this is awesome. Thanks for making this lecture.
@friendlyneighborhoodimmuno71923 жыл бұрын
Thank you for your kind words! Let me know if there’s other topics you would like to see me cover.
@user-ue6zj2pu2g2 жыл бұрын
better than CG or computer pictures.!! great paiting and educating skills!
@roberta.s22033 жыл бұрын
As a low platelet person, I found your explanation very informative. I was prescribed Furosemide which I took for about 6 weeks until another routine check of my blood revealed platelet count of 50K. It has been low for sometime since I have an autoimmune liver disease, PBC, but my Dr. was alarmed and told me to cut down or stop taking the diuretic which has the side effect of lowering platelet counts. Trying to live with this, I recently retired (at 70) to go at a slower pace and dedicate time to my health.
@friendlyneighborhoodimmuno71923 жыл бұрын
I’m so glad you found the video helpful! I hope stopping the Furosemide will increase your platelet count. Best wishes for your health.
@rhondajohnson1193 жыл бұрын
@@friendlyneighborhoodimmuno7192 my brother has liver cirrhosis. He wakes up sometimes with blood in his mouth. He takes Lactolose, Xifaxin, furosemide, lasix, . The doctors have never said anything about duretics cause low platelets count. Is this true?. They give him duretics so he didn't accumulate water retention on his stomach lining . He's had to have water drained off his stomach twice in last 8yrs. I loved your video. Thank you for your hard work. My brother took the jab against his doctor's advice and the rest off our family won't do it. To many people getting blood clots and adverse reactions. Doctor the work you do is very very important in the medical field we need more like you. Blessings to you and your family.
@friendlyneighborhoodimmuno71923 жыл бұрын
@@rhondajohnson119 Thank you for your kind words. I am sorry to hear your brother has liver cirrhosis. I am not an expert on liver diseases, but I did check out each of the medications to see if they were associated with low platelets. Xifaxin seems to be very helpful during liver cirrhosis: pubmed.ncbi.nlm.nih.gov/22098272/ One the other hand Furosemide (Lasix) has been identified as a drug that might cause low platelets. pubmed.ncbi.nlm.nih.gov/23625769/ medlineplus.gov/ency/article/000556.htm Perhaps speak with your brothers doctor about checking his platelet levels and potentially consider another medication. Take care!
@rhondajohnson1193 жыл бұрын
@@friendlyneighborhoodimmuno7192 thank you for your response. Yes I will ask about duretics lowering platelet levels. Keep up the excellent videos.
@elizabethwilliams3267 Жыл бұрын
Thank you for the links. My 2 sisters have pbc caused i think by hepatitis, not alcohol abuse. I have now developed low platelet count the most recent fbc showed 96 for thrombocytes. Gp is reluctant to refer me to haematologist at what he considers to be an early stage. My feeling is 'why wait?'. The condition has been monitored for >12 months and shows a steady downward trend. Receiving zero treatment, only monitoring. Why wait?
@AnotherPilot13 жыл бұрын
Can I sharpen Teachers pencils for extra credit?!? This is excellent...it's so good the world has a few people who can speak extemporaneously as a subject matter expert. Thank you, Doctor.
@edwardashby9979 Жыл бұрын
Very informative❤explained alot to me. I never get sick, when I get cut I stop bleeding fast, don't have headaches. The blood test show I have low platelets. I do bruise easily my doctor says I have thin skin is why I'm bruising I'm in my 70s. How does milk products play a part in my low platelets. I mainly eat cheese, milk, homemade yogurt ,eggs, pound and half of nuts a week,all greens, vegetables,alot of fruit,very little bread, no beef,a little chicken and mackerel.❤❤
@rajchoudhary18734 ай бұрын
After having infected from dengue platelets around 50k. No improvement from last 6 month's. Hematologist says antibody IFA weak positive
@andrewmortensen54112 жыл бұрын
Several days after the 2nd Pfizer shot my wife presented with petechiae, nose bleeds and bruises over her body. Her platelets, neutrophils, lymphocytes and RBCs were way below the reference ranges. She was Hospitalized in emergency for 10 days, released and then reinstated to emergency 2 days later for another 5 days. After evey test under the sun including 2 bone marrow biopsies because they thought it was cancer stemming from the bone marrow, neck and armpit biopsies, bone scans and on , she was finally told it was an autoimmune attack her doctors were and are suspicious of it being vaccine induced. 3 months later she goes toothed hospital once a week for blood tests. Her platelets are going down again. With IVIG and steroids her blood products mentioned above wen from platelets at 4 to 250 , neutrophils from .6 to 3 and lymphocytes into the middle of the range. Platelets are now at 60 and dropping. She is likely going to get treated with rituximab this week. It was a terrible time for her and the family. We hope her next treatment improves the condition.
@Hobbit1832 ай бұрын
I had less than 1 platelet and was bleeding from everywhere. Never been more frightened in my whole life. Doctors thought it was cancer at first but it was covid. Luckily it worked with high doses of prednisone which made it rise to like 60 within a week
@dg96752 жыл бұрын
My first dose of astrezeneca gave me ITP (first dose was about 2 months ago), so far ive had medications and 1 immunoglobulin transfusion, is this temporary of chronic?
@ungmd213 жыл бұрын
Great Lecture. I am a physician that has had thrombocytopenia for over 20 yrs.The etiology is still a mystery. I hovered around 40K . 3 bone marrows over the years have not revealed any myelodysplastic features except an MCV of 113. After the Covid 19 Pfizer vaccine a routine check showed my platelets were down to 17K. I got a bunch of immune studies that did not show any platelet antibodies. I got steroids with were only minimally helpful. Now getting Rituxan which I hope will help. Any thoughts? You cam PM me
@friendlyneighborhoodimmuno71923 жыл бұрын
Thanks for the comment. I am sorry to hear you have had to battle with thrombocytopenia for so many years. It is interesting that you don't have antibodies for platelets, and yet the treatment chosen is to further suppress the immune system instead of boost megakarocytes (Romiplostim)? Does your physician suspect ITP? I'll PM you more ideas soon.
@Lighthouse6104 Жыл бұрын
I have itp and lupus and Rituxan works extremely well for me.
@soulsearcher226x813 күн бұрын
So how do we cure it? My sister is currently in a critical state and doctors here don’t know why…recently being treated for TTP but the plasma exchange is not working! Please help!!!
@andioei99293 жыл бұрын
Thank you from Indonesia. Very good explanation.
@AmanKumar-vq1vq Жыл бұрын
Kindly elaborate on the function of thromboplastin and thrombokinase
@TheWayTheCookieCrumble Жыл бұрын
Thank you for this ! Awesome video very clear
@tiffanybeard2 Жыл бұрын
appreciate the information. Just diagnosed with this and currently under chemotherapy for it, researching why chemo for treatment.
@friendlyneighborhoodimmuno7192 Жыл бұрын
I hope your treatment is successful 🙏
@Lighthouse6104 Жыл бұрын
Is the treatment your taking called rituximab or rituxan?
@yesiromero8852 жыл бұрын
I am so scared to get the vaccine because of this, I have ITP only when I’m pregnant but even if I’m not pregnant my platelets tend to stay on the lower side. Is there anything that helps boost your platelets besides a transfusion and steroids.
@davidtayloromara2 ай бұрын
Papaya leaf extract
@demonshelby13113 жыл бұрын
I had my spleen removed the to ITP and I have heard that I can't make lymphocytes to fight off the covid. I would appreciate your thoughts on this
@susanjones4593 Жыл бұрын
I love your teaching style!
@m.m.m.c.a.k.e2 жыл бұрын
You are a kind soul
@xw84622 жыл бұрын
I dont have ITP now, but my mum died from it. I have same blood type as her. Shall I go for Pfizer?
@kashishbhambra1346 Жыл бұрын
My 9 year old brother is currently experiencing thrombocytopenia. That in addition to neutropenia as well. His platelet count was less than 3000 recently and they havent been able to find a cause. He is not symptomatic at all but he had bruises all over his body and whenever platelet count drops below 10000 he develops petechiae on his feet. His gums have bled a few times too. They did a blood culture and bone marrow biopsy and found nothing out of the ordinary really. The only treatments that help temporarily are platelet transfusions and IVIGs... they might start him up on a low dosage of sirolimus medication soon. This video really helped me understand better... A job well done teaching. Do you suspect thrombocytopenia and neutropenia in his case could be associated with the COVID 19 vaccine (he got his second dose in January) in his case doctor?
@Dramatohbandtahai3 ай бұрын
Did you find your answers I also have the same condition how to deal with it
@icediamonds112 жыл бұрын
I have a question I got covid about 5 months ago and now I took blood test and it shows I now have low platelet can the virus cause that. Never got the jab ?
@Dramatohbandtahai3 ай бұрын
Did you find the answer
@icediamonds113 ай бұрын
@@Dramatohbandtahai yes it caused it but it's normal now
@Dramatohbandtahai3 ай бұрын
@@icediamonds11 my platelet is low how to it is because of covid
@icediamonds113 ай бұрын
@@Dramatohbandtahai I don t know my doctor told me that covid can cause it in certain people. I was one of the unlucky people I would just go to the doctor and run test
@crystalconner3494 Жыл бұрын
Thank you. Very well explained.
@sathishj20723 жыл бұрын
This is Sathish aged 24 from Chennai . I am suffering from thrombocytopenia my average platelet count is less than 1.5 lakhs , and I have also suffered from yellow fever and thypoid in the previous years . What vaccine should I take covishield or covaxin.
@friendlyneighborhoodimmuno71923 жыл бұрын
Hi Sathish, I’m sorry to hear you have thrombocytopenia. I always say to consult with your doctor before making health decisions, but I will also give you my opinion. It seems like you have mild thrombocytopenia, but I would recommend getting your platelet levels checked after your first vaccine shot. Covishield is a viral carrier vaccine meaning that a DNA virus from a chimpanzee will bring the information about how to make COVID antibodies into your cells. Covaxin is an inactivated COVID virus. No active virus in Covaxin.
@friendlyneighborhoodimmuno71923 жыл бұрын
If you have not had any bad reactions to traditional vaccines Covaxin might be a better choice for you. Ask your doctor too! Take care and I wish you well!
@yelenak61533 жыл бұрын
My platelets have been hovering around a 100 over the last 5 years. Not really sure what caused the drop - could this be a side effect of certain common antibiotics? The only trigger I could think of. My antibody blood tests came back normal, and blood marrow seems to be healthy. Yet, i have not been able to bring the levels back up. In addition, I have a Factor V Leiden single gene mutation (prone to clots), and Type A blood type - not a fun combo to have during Covid! Have my 1st dose vaccine next week, followed by a blood test 2 days out and 12 days out. I’d appreciate any tips! And thanks for the video - very helpful!
@friendlyneighborhoodimmuno71923 жыл бұрын
Hi Yelena! Do you mean 100 or 100K? It seems like based on your tests that your doctors have not found immune cell involvement. Perhaps there is a genetic reason behind your low platelet count? It sounds like you have made a smart plan with your doctors. Good job taking care of yourself! I think the two blood tests and monitoring your symptoms is the smartest thing to do. I don't have any specific advice for boosting platelets, but relaxing, eating well (fish, olive oil, avocados etc), spending time in nature are all immune boosting activities. I wish you the best!
@yelenak61533 жыл бұрын
Thank you doctor! This does not seem to be a genetic predisposition, years ago my platelets were in 200k...Look forward to more videos.
@tenzingagya3 жыл бұрын
Thank you from Taiwan
@moij5962 Жыл бұрын
Can you please explain about increased platelet.
@karenperise8495Ай бұрын
From Video: “1 ml of blood contains 150 billion platelets” Is it billion or thousand?
@peggytengan9959 Жыл бұрын
I have been getting Romiplostim injections almost every week. Juggling as low as 21L(21,000) to 164L for the past 4 years. I. E. One weekly blood test result was 114L and the following week test result turned 32L😰☹️ kept resulting this way😞. Strange that I have seen only 2 or 3 bruises on my body for the past 4 years. Also, took 80mg/day steroid for about 3 months when my platelets were down to 30Ls range. Then my face turned=huge pumpkin 🎃 + steroid did not work well in my body. The above injection=N Plate works better for me but the cost is just UN Believable. Plus, side effects in digestion and insomnia is just too much… Weekly blood tests + hard tissues on my arms (due to that hard to draw blood) gives me anxiety😰😰
@Brian-bw3uu2 жыл бұрын
Rasputin and beholders. I didn't see that coming. Lol
@fullkebab8791 Жыл бұрын
You help me a lot.. thank you very much 🙏🙏… do you have some social media to follow you for more information
@vikkiprevette29349 ай бұрын
Research OPC 3 for platelets- you can google just about anything these days - bioflavonoids raise your platelets as well…
@karenmiller62582 ай бұрын
My son has just been told he has this. I immediately thought of the covid jabs he’d had. That’s how I ended up here. Although the hints at this are found in the comments, I cannot help but wonder if there has been an increase in ITP since. Someone, somewhere is counting.
@meoweth49803 жыл бұрын
After my vaccine i had a blood pressure cuff leave nasty petatchie red marks on my arm that didn't heal for a week. My platelets were normal range, so what could cause that? I've had really slow healing dermatitis from a heart monitor too.
@NuNugirl3 жыл бұрын
I am very scared of getting the vaccine. What will happen if my platelets drop so low again. My Hematologist told me years ago, I had no other choice, but to have a Splenectomy. I have been healthy for so many years. I’m more scared of ITP than Covid. Do you think the splenectomy will keep me safe from a possible relapse? Should I risk getting the vaccine? I don’t want to over work my lymph nodes, because sometimes they get so swollen and painful. I trust you , because you are a immunologist, and know so much about this nasty rare blood disorder.
@friendlyneighborhoodimmuno71923 жыл бұрын
Thank you for sharing that with me Nora. I'm sorry you have to deal with that. It looks like a splenectomy for ITP is about 50-60% effective. That's honestly a tough call. You may be one of the rare people who should not get the vaccine. How long have your platelets been healthy levels for? Here's a paper on splenectomy success. pubmed.ncbi.nlm.nih.gov/10676920/#:~:text=Splenectomy%20has%20a%20success%20rate,ITP%20patient's%20response%20to%20splenectomy.
@docn.2352 жыл бұрын
Very very nice to explain these issues to laypeople, but pls. pay attention to spelling, i.E. MegacarYocytes (from greek: karuon= kernel) where the Y is missing or Thrombocytosis where the missing Y showed up after the "Th" :-) Thanks!
@friendlyneighborhoodimmuno71922 жыл бұрын
Thanks! I do need to work on my spelling issues. I have trouble with "el" and "ie."
@MsDiesel20062 жыл бұрын
Do you know of any correlation with Ehlers Danlos Syndrome and ITP?
@debashreechatterjee40212 жыл бұрын
Ma'am , my husband has corona and we found his platelets low ...in the range of 1 lac to 1.25 lac...normal range for him is 1.6 lac (seen in earlier CBC)...he took covishield booster 12 days ago....do u think any relationship in low platelets? We are observing his count ...pls pls tell
@SK-cb6wz3 жыл бұрын
Thank you so much
@Leena9254 Жыл бұрын
My doctor told me today I have really low platelet she wants to see me tomorrow 😨
@Shelilah413 жыл бұрын
My blood platelets dropped after the first dose of the vaccine and I have never had that happen so my question is it was not very very low but will my platelets go up on their own
@friendlyneighborhoodimmuno71923 жыл бұрын
Yes they will. Your megakaryocytes are in your bone marrow renewing your platelets all the time. Your platelet levels should be back to normal in 1-2 months. I would check in with your doctor and get another platelet count before your second vaccine.
@skandinikumar27703 жыл бұрын
How many days after the vaccine you got your platelets levels checked ??
@juliehammonds3658 Жыл бұрын
My partner had very lowe plattletts after vaccine all ok now had 4 more vaccines since plattletts fine with them.
@michelleunzueta2 жыл бұрын
Last March after my first dosis of Pfizer vaccine I got bruises on arms and legs…on that time any doctor answers why this happened, I was scared, the bruises gone without any medication but now I’m scared to have the second one, also my two daughters got them with the same side effects. How can I make an appointment with you 🙏🏽 I need answers to prevent this please.
@friendlyneighborhoodimmuno71922 жыл бұрын
Oh you should have your platelets checked by your regular primary care doctor. I would do that before your second shot. I'm not an M.D., I'm a PhD, so I can't order blood work.
@lindsandkev5 ай бұрын
Do not take anymore of that poison.
@dammitol25mg193 жыл бұрын
I appreciate these videos but must ask: how is it possible to do a PhD's worth of immunology without learning to spell "vessel?"
@friendlyneighborhoodimmuno71923 жыл бұрын
Dammitol! Oh yeah, it's overreliance on autocorrect. I have issues with all ie words like protein and receive too.
@GaryJames8643 жыл бұрын
@@friendlyneighborhoodimmuno7192 "Go to your pharmacist and ask for Damnitol. Guaranteed to relieve stress!" Dan Aykroyd on Saturday Night Live circa 1974 "relieve" got autocorrected, so I guess Damnitol did cure one bout of spelling anxiety.
@dhockeyplayer833 жыл бұрын
Hello there. Would this same concept apply to your annual flu shot as well? And if so, then can someone with ITP in the ranges of 100k-150k that has taken the flu shot for several years now and done well with their counts, expect a similar result with the covid vaccine? Thank you for your time.
@friendlyneighborhoodimmuno71923 жыл бұрын
Good question. It would be encouraging to know that the flu shot has not affected your ITP. I would always check with your primary care doctor about ITP and vaccination. It does seem likely that you would experience something similar with the COVID vaccine. You can set up blood draws one week after each shot to check your platelet levels with your doctor.
@dhockeyplayer833 жыл бұрын
@@friendlyneighborhoodimmuno7192 Thank you for this info. One last question, is there a correlation between the covid vaccine and neutrophils and lymphocytes levels?
@FinancialMaintenance Жыл бұрын
Thanks for answering some of my questions with this video. I want to blame the covid vaccine but don't believe that is fair. My very healthy son got his covid vaccine. About a month later he went in for is checkup. His blood draw had him at a little over 350k platelet count. He got his flu vaccine then about a month after covid Vax. His counts plummeted to 4k about 4-5 days after flu Vax. He rebounded to 160k after 2 months on his own. Then he plummeted again. They tried a heavy dose of prednisone and he went up and dropped again to about 19k a week after the prednisone. Now they are starting altrombopeg. Any idea to explain the cause and reaction of what might have happened?
@gnosisdespirit9 ай бұрын
Vaccines are toxic. Watch "The Truth About Vaccines" Docu-series (should be able to find it on the internet)...
@hombo883 жыл бұрын
Can aspirin prevent vaccine induced thrombotic thrombocytopenia?
@friendlyneighborhoodimmuno71923 жыл бұрын
From my research, I would not recommend using aspirin if you have thrombotic thrombocytopenia. It can lead to excessive bleeding. Always consult with you doctor before changing your medication. pubmed.ncbi.nlm.nih.gov/7032379/
@kimberlydavalos83123 жыл бұрын
I had the first dose of Pfizer my platelets were 140 before and about 6 days later were 73 I was hesitant to take the vaccine at all and was concerned so was checking the levels What should I do Thank you
@friendlyneighborhoodimmuno71923 жыл бұрын
I would check in with your doctor, and express your concern about the reduced platelet levels. Did your doctor check your platelets? Do you have a history of any issues with low platelets? Maybe you should wait before taking your second shot.
@dhockeyplayer833 жыл бұрын
Hi Kimberly. I've heard of people with ITP having a dip in their platelets temporarily after the vaccine. Have you noticed any changes since the 73 count?
@akashkuri91133 жыл бұрын
If a person who has blood clots and low platelets also and should he or she take the covid vaccine or not please reply ...
@friendlyneighborhoodimmuno71923 жыл бұрын
That's a tough question. I think it depends on several factors and it is ultimately a personal decision. 1) If low platelets are not linked to an autoimmune disorder or if the low platelets are only mildly low (140-100K) then perhaps it would be appropriate to take the vaccine. Several people who watched this video did take the vaccine and planned a blood draw with their doctors to check their platelet levels 7-14 days after the vaccine. You could take this approach. 2) If you are prone to clotting the viral based vaccines like Johnson&Johnson and AstraZeneca may not be right for you. Although it is unclear if the people taking these vaccines are having more clots than the average population. 3) How dangerous is COVID to you personally? Do you work at home? Then maybe you can isolate yourself for another year and skip the vaccine. Do you have lots of family to care for? Do you have any underlying conditions that may make COVID worse (diabetes, smoking, ect.)? After you consider these factors you can make a plan with your doctor. Best wishes for your health.
@clday2179 ай бұрын
I believe you said 150 million but that should be 150 thousand. In the US the range is 150-400 thousand. And I have ITP from the Hepatitis B vaccine which is not genetic.
@alexandarshay16043 жыл бұрын
My platelets are 135k-150k from last several years for unknown reason, I dont know if I have any clotting issue or not, shall I avoid vaccine at all? Or avoid only viral vector based vaccines (AZ, sputnik, jj, cansino)? Can I take the chinese Sinopharm or sinovac? Many thanks
@friendlyneighborhoodimmuno71923 жыл бұрын
Your platelets are within normal range (150-400,000), so perhaps you have mild thrombocytopenia. It is a very personal decision to get the vaccine, and I suggest you consult with your primary doctor. If I were you, I would think about how dangerous it would be to contract COVID and compare it to the dangers of thromobocytopenia. For example, does your job expose you to a lot of people. Can you isolate for another 6-12 months? Do you have underlying conditions like asthma? If you do not have underlying conditions or a dangerous job perhaps it is best to wait. However, if you do have some conditions, jobs or at risk family members perhaps it is best to vaccinate. Several people who replied to the video said they are getting the Pfizer vaccine and plan to get a blood draw 7-10 days after their first shot to check platelet levels which is a good plan. There is some evidence that getting COVID is worse for clots and low platelets than getting the vaccine itself. newsroom.heart.org/news/guidance-on-treatment-for-rare-blood-clots-and-low-platelets-related-to-covid-19-vaccine I'm sorry you have to make a difficult decision, and I wish you well.
@alexandarshay16043 жыл бұрын
@@friendlyneighborhoodimmuno7192 Many Thanks
@skandinikumar27703 жыл бұрын
My husband platelet count is 190k, can he get the vaccine?? he has pulmonary embolism in 2017 and he is on blood thinner xarelto
@friendlyneighborhoodimmuno71923 жыл бұрын
I would ask your husband's primary doctor. 190K is a normal platelet count. If he is on blood thinner, you may need to ask your doctor if mRNA vaccines (Pfizer and Moderna) are safer than virus based vaccines (AstraZeneca or Johnson and Johnson). So far could not find any strong connection between blood thinners and issues taking the COVID vaccine. www.medpagetoday.com/infectiousdisease/covid19/91624 I hope everything goes well with his vaccination!
@skandinikumar27703 жыл бұрын
Thank u so much for the reply.. his doctor said he could go ahead take Pfizer vaccine. Should he be checking his platelets count after the vaccine?? If yes how soon after the vaccine should he be testing for platelet count ?
@friendlyneighborhoodimmuno71923 жыл бұрын
@@skandinikumar2770 Most people see symptoms of low platelets (bruising, bleeding, lethargy) 72 hours after the vaccine. If your husband experiences any of these symptoms or severe headache I would see a doctor immediately. If your husband does not see any of these symptoms, it would be safe to check his platelets about 10-14 days afterwards. Make sure they are checked before his second Pfizer vaccine! Best wishes
@stellaforhandle3 жыл бұрын
Hello and thank you very much for the useful video. I am worried for my mother. She wasn't allowed to have the second dose of moderna due to number 40.000 of platelet. She then consulted a hematologist and she started medication to raise them. Today she is taking the vaccine with around 100.000 platelets due to the medication. I am worried both about the effects of the vaccine but also will this medication that she still takes in lower dose interfere with the vaccination in any way? Could you tell me your view on that? Because our doctor was a bit dismissive to explain this.
@friendlyneighborhoodimmuno71923 жыл бұрын
Thank you for the kind words, and I am sorry to hear your mother has low platelets. I am not sure what medication was prescribed to your mother. I can look into it if you let me know. If the drug is boosting the megakaryocytes then it should not interfere with her immune response to the second vaccine. If the drug is boosting her platelets by suppressing the immune system your mother may make fewer antibodies than someone not on the medication but she could still make antibodies.
@stellaforhandle3 жыл бұрын
Thank you very much. The medication is called medrol (16mg), she has taken 2 pills per day for 7 days and 1 per day at the moment. I was wondering would it be possible to check the level of response with an antibody test later on? Thank you sincerely for your response. :)
@friendlyneighborhoodimmuno71923 жыл бұрын
@@stellaforhandle Medrol does suppress the immune system, but one pill a day will probably not affect her immune response and antibody count too much. Many doctors agree that if you have a chronic inflammatory condition like arthritis or low platelets to continue taking the medication prescribed to you. The experts at Cleveland Clinic agree this is the best choice. You could ask for an antibody count to check her levels. I have a friend who is a nurse practitioner and she got her antibody levels checked after her second vaccine. health.clevelandclinic.org/should-you-avoid-certain-medications-or-treatments-before-getting-vaccinated-for-covid-19/
@georgeelgin39034 ай бұрын
your hypothesis, that rates of thrombocytopenia might have been a result of mRna vaccines doesn't seem supportable in population studies. Evolutionary or Revolutionary ? i meant the immune system not eating less peanut butter.
@NK-gb3bk3 жыл бұрын
I had subdural hematoma in the past. I was taking blood thinner at that time. My doctor asked me to stop taking it. Then, bleeding was gone. Now, I can't decide whether I should take a covid vaccine or not. I have had hypertension, and taken telmisartan, ARB and amlodipine. I wonder whether I can take a covid vaccine.
@friendlyneighborhoodimmuno71923 жыл бұрын
Sounds very complicated. I would recommend you ask your primary care physician to check your platelet levels before taking the vaccine. If they are above 150K then you would be eligible to take the vaccine. Several people in the comments here have taken the Pfizer vaccine without dropping their platelet counts. Have you had adverse reactions to any other vaccines?
@NK-gb3bk3 жыл бұрын
@@friendlyneighborhoodimmuno7192 Thank you so much for your kind reply. OK. I will ask my primary care doctor to check my platelet levels. I took flu vaccine once before. It was ok at that time. I heard that Novavax vaccines will get FDA emergency approvals in September. What do you think of Novavax vaccine? I heard it was made of traditional method. Thanks again for your reply.
@friendlyneighborhoodimmuno71923 жыл бұрын
@@NK-gb3bk Novavax looks like a solid vaccine choice to me, especially if you haven't had an issue with the flu vaccine. You are correct that it is a close to a traditional vaccine because it is just a protein (the spike protein) from the COVID virus. So no mRNA(Pfizer and Moderna) and no viral vectors (AstraZeneca and J&J). It is grown in moth cells, but unless you are allergic to moths I don't see any issues. I am mostly kidding about the allergy to moths. Some people cannot handle the flu vaccine because they are allergic to chicken and the virus is often grown in chicken eggs. I wish you the best! Let me know if you have any other questions.
@NK-gb3bk3 жыл бұрын
@@friendlyneighborhoodimmuno7192 Thank you so much for your quick reply. I almost decided that I will take Novavax vaccine. I am very lucky to find your KZfaq video. Thanks again. 😊
@GaryJames8643 жыл бұрын
@@NK-gb3bk I also have hypertension and am on an anticoagulant. I am in the Novavax clinical trial. But definitely check with your primary healthcare provider before getting it yourself, we have very different histories. And never get your medical advice from some random dude in KZfaq comments. I can say from personal experience that the vaccine reaction was about the same as I usually get from the flu vaccine, very mild. Two jabs are given 2 weeks apart. Novavax has a lot of advantages for use in places with less well developed medical infrastructure. Proven technology that the company has a couple of decades of experience with. Much easier storage and administration protocols for your providers.
@andycochrane41313 жыл бұрын
Ffs she spelled “vessel” incorrectly.
@friendlyneighborhoodimmuno71923 жыл бұрын
Oh God. You notice everything. I am not a great speller. I will be honest.
@andycochrane41313 жыл бұрын
@@friendlyneighborhoodimmuno7192 I’ll forgive you. This time.
@docn.2352 жыл бұрын
Wow, thats No 3. But I didn't notice after Megakarocyte and Thyrombo... Anyway, this is science, not spelling bee. Never mind.
@Anonymous-ny7ci3 жыл бұрын
Should I take the Covid-19 vaccine if my platelet count is low or was low recently? Now count is at low threshold: 1,50,000 (Got tested in December 2020)
@friendlyneighborhoodimmuno71923 жыл бұрын
Hi Akhil! Sorry your platelet count is on the low side. It's a tough call about getting the vaccine because if your platelets are low due to your immune system then the vaccine may lower your platelet count further. I would ask your doctor what they think, and then you could make a plan. I would say think about how risky your job is, perhaps wait and see if we can reach heard immunity. Maybe getting a single vaccine shot like the Johnson and Johnson is better for you, as long as you don't have any history of blood clots. Sit down with your doctor and make a plan. I wish you the best.
@pracharprasardotcom37703 жыл бұрын
How many platlates in one gaint platlates plz guide ?
@friendlyneighborhoodimmuno71923 жыл бұрын
@@pracharprasardotcom3770 Hi! One Megakaryocyte (giant platelet) makes 5000-10,000 platelets. courses.lumenlearning.com/boundless-ap/chapter/platelets/#:~:text=higher%20levels%20of-,thrombopoietin.,cellular%20components%20are%20fully%20depleted.
@pracharprasardotcom37703 жыл бұрын
I have also low platlates in cbc anlyser & have gaint platlates can these gaint platlates meaning many platlates or not
@friendlyneighborhoodimmuno71923 жыл бұрын
@@pracharprasardotcom3770 I understand now. Giant platelets are different from megakaryoctes. Megakaryoctes live in your bone marrow, not your blood. If you have giant platelets in your CBC (which measures blood) it can be a problem because giant platelets don't work as well at stopping bleeding. The smaller, regular sized platelets work better to stop bleeding. Has your doctor give you any information or a diagnosis? Does anyone else in your family have giant platelets?
@bluewave7120 Жыл бұрын
My platelet count became low after the covid vaccine. Is this temporary or permanent?
@Dramatohbandtahai3 ай бұрын
Did you find the answer I want to know the same
@bluewave71203 ай бұрын
@@Dramatohbandtahai MPV can improve in some people after the effects of the MRNA vaccine reduce over time By design the vaccine raises sub class igg4 levels and can pre dispose some people to auto immune illness If you are allergic to the vaccine you will be far more susceptible to long term blood related & auto immune concerns
@Dramatohbandtahai3 ай бұрын
@@bluewave7120ohh I already had autoimmune condition before vaccine now I have disease which is not getting better
@bluewave71203 ай бұрын
@@Dramatohbandtahai What autoimmune condition did you already have? How many vaccine boosters did you have? Have you had your subclass IGG4 antibodies tested? People with pre existing autoimmune conditions should not have been vaccinated with the covid MRNA. Make sure your vitamin D level is normal if it is low your your immune system cannot function properly How are you doing now? Don't give up we can overcome this situation
@bluewave71203 ай бұрын
@@Dramatohbandtahai How is your platelet count now? What I have seen is small fluctuations up and down yet over all staying down unfortunately
@sirnicolas213 жыл бұрын
very nice video.... but that pencil scratching.....
@friendlyneighborhoodimmuno71923 жыл бұрын
Ah thank you for letting me know! Some people love the sound of coloring and others hate it. I might try some videos with voiceovers and see how it goes.
@sirnicolas213 жыл бұрын
@@friendlyneighborhoodimmuno7192 yea it killed half my Megakaryocytes :/
@friendlyneighborhoodimmuno71923 жыл бұрын
@@sirnicolas21 Lol sorry about that. Hopefully you will recover soon.