"When people are relaxed some of the best ideas come into their heads" That hit me like a ton of bricks because of course thats why our best ideas happen in the shower.

Loved the part about the coffee room not being allowed to close if there are people talking in there.

I was hoping he was going to snort it off the spoon at the end.

At 80 cups of coffee, the water will probably be more toxic than the caffeine

Whenever i spill something: "Scattering atoms everywhere"

To anyone questioning the practical methods - this was only a quick demo. The guy knows what he's doing, honestly!

that ummhu at the end sounded so disappointing

I drank coffee every day in college and it did nothing for me except give me the super-shits

_"80 cups a day is lethal. do not approach that al all"_ *Me looking at my 20th cup of coffee* : Well, I am safe.

10:52 "Thank you very much."... "Hmm, mmm.... I'm off to do some rails.".

7:09 "hah, kek.." 7:14 "oh.."

I'm deeply saddened that they did not recrystalize. :(

It is so cute seeing Sam gushing over that little necklace.

this video makes me want to be a chemist, not because caffeine was involved but how they removed the caffeine from coffee was really cool

Caffeine is THE drug, every country has their favorite pick up. It is quite addictive too as like other drugs you develop a tolerance, caffeine blocks a major neurotransmitter, adenosine, which builds up naturally over the course of the day and makes you feel tired. Caffeine fits the same place as adenosine but does not possess the same depressant effect, this reduces the space for adenosine and blocks it's. In response your body develops a sensitivity to adenosine producing tolerance and resulting in a withdrawal syndrome if stopped abruptly. The vast majority of the worlds population consume caffeine in some form on a daily basis and most would feel a noticeable loss in energy without it. The vast majority of the population or earth therefore are at least mildly dependant on the drug. Great news for plants that produce caffeine, they have us hooked so we'll make sure they survive and reproduce. A clear symbiosis where two unrelated species provide a service for each other. It would appear that tea and coffee have lured us in like bees to nectar.

I would really like to see Capsaicin extraction.

I remember doing this exact extraction in college, then when done, I had about 250 mg of pure caffeine, so what do you think I did with it? Like any young college student, I railed it up and snorted it much to the amusement of my lab-mates. Of course I regretted this action about 5 seconds later, my nose felt like it was on fire, and about 15 minutes later I thought I was gonna have a heart attack. But don't ask me what I did with the eugenol I extracted out of cloves... haha!

Curly hair professor rocks :)

He's describing a very interesting body reaction, creating the antidote for caffeine. This effect takes place with all drugs consumed and it is not only linked to time but also to the place that you are used to take drugs. Drugs used in unknown areas will have a way stronger effect, because the body does not start the counter reactions to the drugs.

That's some weak coffee.

After drinking coffee for awhile, it doesn't make me hyper. It makes me rather relaxed but still a bit more 'awake'.

Ahhh, I remember doing the extraction and recrystallisation in my 1st year chem at uni! So nostalgic!

That was the most genuine and endearing change of hearts I've ever seen on youtube.

Einstein once called coffee the beverage of geniuses (Jerry Einstein from Peoria).

Lol! I love how Dr. Tang changed her mind after seeing the necklace!

I'm only 13 but in the last few weeks I've been watching PeriodicVideos, I've learned more information on a decent portion of the periodic table than all the information I have learned in school in the last year. I've been interested in learning more about chemistry for a while and this channel has kept it very simple and very interesting as well. Thanks!

Wow. 8 year old videos of this channel still blowing my mind. I liked the 3-story interlaced narrative as well.

Caffeine was developed by nature as an pesticide. Everytime you drink something with caffeine, you're drinking pesticide. ;P

The 80 mg he got was less by a significant amount due to inherent inefficiencies in the experiment. Starting with getting the caffeine out of the original coffee solution especially, this kind of thing is quite hard to do. I have done caffeine separation in my university's lab on four separate occasions, and I'm still thrilled when I get over 30% of my expected chemical yield.

He said 30mg of caffeine for 6 cups of coffee? That's not right. Should be closer to 600mg.

This an old video but one of the more relatable to many. I'm a metallurgical technician so have never had much to do with organics other than as sample mounting materials, coatings and reagents for my assorted etching compounds. I love this channel.

9:02 looks kinda like saturn lol, without the rings

"Thank you very much" "Mm hmm. That'll be £600"

Strong coffee reduces the pain of jellyhead, once suffered by those who handled explosives containing nitroglycerin.

*It's not the coffee helping the scientists to win a Nobel prize but the aura created by brilliant people in that room while relaxing by drinking something to stimulate you, this does not necessarily have to be a cup of coffee.*

3:15 Sodium hydroxide shouldn't deprotonate caffeine Sodium hydroxide deprotpnate tannin and extract tannin to water-layer

8:01 Dr. Rob Stockman demonstrates his "cold finger"

I feel like I'm listening to drug addicts explain why their drug isn't that bad.

He isnt lying when he said some of your most brilliant ideas come to you in a relaxed state. I'm working on one of mine right now. I cant wait till its finished.

That is such a wonderful video! In fact,every video of "Periodic table of videos" is wonderful! As a great chemistry lover I am really fascianated! Greatest respects from Albania🇦🇱

i only drink cola also, fry drank 100 cups but didn't die

the only thing I could focus on was that screen saver moving from screen to screen.

Oh, love his hair. Currently my style while doing a chemistry class. It paint a big smile on my face. Thanks

I have the molecule tattooed on my calf. Used to work nights so was and still is a huge part of my life.

Oh wow, the Kek clip just REEEEd pretty quietly after he mentioned it.

Caffeine is the only compound in coffee that is soluble in ethyl acetate?

Keep doing this excellent work! I became a fan of your method to explain practical chemistry.

In the words of Jess Pinkman, Mr. Stockman, you're a goddamn artist!

Could someone make something like a litmus test to easily tell how much caffeine is in a drink? I'd buy that.

100 mg from SIX cups of coffee? These Brits must drink EXTREMELY WATERED-DOWN coffee! Mayo Clinic website says 95 mg to 200 mg from a typical 8 oz. cup of coffee!

Its not so much the coffee in discussions but the fact that people across a department are communicating in a casual setting which increases efficiency. There was an Australian study into it but i cant remember it unfortunately to cite it.

Those clips are insanely useful

"You usually see it on people's coffee cups..." And I was thinking our office was particularly nerdy :D

I would like to know more about this "caffeine-blocking product" the body creates and how it works.

My chemistry teacher has a trinitrotoluene molecule tattoo, because he’s the bomb, and he was talking about getting a caffeine tattoo too. Since you mentioned how you see it everywhere.

Thank you for your amazing video and job. Congratulations sincerely!

Who knows if it is pure? Maybe there is something else in the end product. Why not use use Nuclear Magnetic Resonance to determine the purity of the product? And was the solution shaken when the product was seperated using the separatory funnel? Sorry, I am a scientist myself, and wonder what exact steps were taken :P

What your body does is, the brain has special receptors that process a chemical that makes you tired. When the tiredness chemical enters the receptor you begin to feel tired. What caffeine does is, it's molecular structure resembles the tiredness chemical (I can't think of the name off the top of my head). So the caffeine begins going into these receptors, using them up so the tiredness chemical cannot get it. therefor reducing tiredness. But over time the body adapts and makes more of these receptors which over time makes the coffee useless. also if you stop drinking coffee after you drank coffee a lot, since you have more tiredness receptors then the tiredness chemical will have more places to go. This makes you go into a withdraw of sorts, being more tired that usual for a while until the body removes these extra receptors.

I love it when a professor works in the lab.

hailing from india and seeing amazing person and learning chemistry as it is my fav subject and currently pursuing it feels lucky.

Wish that the caffeine powder had been collected and placed on a sheet of paper for viewing. Overall very interesting, indeed, though! Thank you!

Didn't even get enough caffeine to chop up a decent line.

Thanks to Destin at SmarterEveryDay, I've subscribed to this channel. This was totally worth it...

What a wonderful gift!!!

Coffee makes me have to poo.

" if youve never had coffee, no doubt you will feel some effects from it" Ive been drinking coffee for 10+ years and every morning ITS LIFTOFF TIME BABYYYYY

I think its so cool that these elements that we see play a part in everything that is. When they link up a certain way it makes such and such. But what tells them to link up in that fashion. There has to be a creator or a code atleast that tells these things to do this.

I loved the camerawork in this video

Well, that put me in the mood for some coffee :-)

this video makes me miss organic chemistry labs :)

these videos are the best...

KEK clips by Dr.KEK kek

I drink mountain dew, pepsi, coffee and tea everyday. I drink them quite alot really. One time I stopped drinking. On day 3 I went close to insanity. Anxiety, tiredness, nausea and general not feeling good. Caffeine withdrawal sure is scary. If you want to stop, do it slowly. Sudden withdrawal is bad.

This channel is the one of the best chemistry channel's I've ever seen (besides Cooking with Walter White)

Actually quite nice watching videos after more than 5 years.. the old youtube site at the picture where matt was holding a coffee makes me miss the old version of youtube.

Coffee has the opposite effect on me, i get tired and sleepy. It's chocolate that gives me a big boost.

9:29 -- LOL !!! Well, gentlemen, now you know how to win a girl's heart (at least if she's a chemist).

A lot of respect to Sir.Martyn....

Love the editing to this video!

That's a really weak coffee if it's 17mg per cup.

This video gave me a craving for some good hot coffee, brb.

I remember watching this program that said caffeine enlightened thinkers in the 1700 and 1800s. These were the times were great amounts of tea and coffee started to being imported to Europe. Also, scholars sometimes liked to meet together to discuss their ideas and coffee cafes were great place to meet.

It's amazing how much tidier his office was back in 2012

Outsmart your body, change the time when you take your coffee.

100 mg from 6 cups of coffee and im sitting here with a rockstar energy drink that contains 240mg caffeine

I immensely enjoyed this video not only because I love this channel, but I am also (if I do say so myself) a rather highly trained barista. One of the things you learn early on as a speciality barista is the different parts of an espresso shot. The fourth and final part (we divide into four. some do three) is dry distillates and caffeine. All the flavour you want comes out early. Caffeine is something good baristas want to limit, since it tastes awful.

I quit drinking coffee 6 years ago and have felt so much better! No more head aches and feeling tired

Wow, this is so molecool!

Couldn't you have acidified the caffeine, crystallized out of solvent, then accounted for the ion? Sulfate?

i just love watching the professional extraction and it makes me think of what sort of things i'd separate if i had access to that lab hehe :)

If you were watching, NaOH is needed to deprotonate the caffeine, thereby making it more soluble in organic solvents. Making dry ice is easy. CO2 is simply sprayed into a bag, or a special block forming apparatus. All of the energy required has already been expended compressing the CO2 into the tank.

the editing in these videos is so perfectly times

Google says a cup of coffee has 95mg.....but you guys only got 100mg out of 6 cups!

That caffeine necklace is great.

I love the double bonds in those molecular models. Cute!

The fact that there was a doctor kek

10:54 Thank you very much Mhm (>Òvó)>

Caffeine: The most widely tolerated and accepted addiction in the world.

RIP Dr. Keck - your name will live on forever

6 cups of coffee is like 400mg? All they got was 30mg?