Thank you very much! Indeed my crystalls were pretty good hehe

Thank you!!! This is one of my favourite videos to make, despite the "low" amount of visits. Thanks for commenting!

Thank you!!

I will definetely do this one day, I promise! Thabks for the idea ;)

You should do one thing, if you don't have any soxhelt extractor,that is add turmeric powder to ethanol or any other solvent you like to use and first do reflux & then distillation.

It should be in the information section in the channel. Just click see email for bussines inquiries or something like that ;)

Thank you!!! You can use whatever strong acid you want yes, even diluted HCl of course. Ehat do you mean by methanol extraction? Methanol is soluble in the reaction mixture (water) and you cant carry an extraction with that. Maybe with another solvent but I think crystallization is the best method, by far. If you are worried about salts in your final product you can do several recrystallizations, and they will give you more and more pure products!

Thanks! Nice question actually. The only risk is that some of the other stuff that it is added to pills gets hydrolised and in the later step of filtering it passes through as it may be soluble. If your pills only have starch I really think it is okay to do the hydrolysis in just one step. Then the crystals are purified in the same way. If it contains other things... probably it is still ok to do that but I would prefer to perform the procedure I show you in my video.

@@Glattuh Thanks!

Thank you!! I will do dont worryy!

Thanks!!!!

Hi thank you very much!!! The distillation is applied to remove the solvent used to extract the acetylsalycilic acid from the tablets. Once the solvent has extracted all the ASA it is no longer needed so by doing simple distillation, we separate the ASA which remains in the round bottom flask; and the solvent, which is ready to be used again if needed. If you refer at what is happening chemichally, well, one could get very serious speaking about this but I suggest you search for simple distillation theory on the internet. That is a separation technique, no chemical reaction is taking place in the process. Once the distillation is done, the powder should be dry yes. I double checked that by gentle smelling and I remember it no longer had the characteristic acetone scent :D Hope that helps

@@Glattuh Yes, I know what distillation is hehe. I meant, how acetone separates (chemically) ASA from the other components of the tablet. Like when you showed it in 4:38. I guess my question wasn´t well formulated, sorry. But you're right, I will search for some information about the other components of the tablet on the internet, some bonds must have formed with acetone, I think. Thanks for your reply! Again, nice video!!. Well explained!!

nice video!!. Well explained!!

Ohh i did not understand you hehe. Well acetone separates the ASA from the tablets because it is the only organic soluble compound there. The rest is mostly starch wich is not soluble in acetone. That is why it is so easy to extract it :D. On the other hand no covalent bonds are formed between the solvent and the ASA, just intermolecular interactions

Hi. It is kind of necessary yes. You need two things for the reaction to develop: heat and time. By applying both you will lose solvent over time so a reflux is needed. If you dont have a reflux condenser you can set it to boil in a beaker or better in an Erlenmeyer flask and top it with a RB flask filled with cold water, or a watch glass but without the water. That way you try to minimize the amount of water that is lost by evaporation but in both cases (more with the second one) you will need to keep adding small volumes of it in order to maintain the volume inside.

​@@GlattuhI have one question : can ya just regard for the calculations done for the reaction ? It would br great to know

Thanks you for the comment¡ There is no silly questions in science :D. Well for the stoichiometry in the reaction... There is not much more to add. You need 3 OH in order to break and neutralize the molecules involved. If you use less it may not go to completion. In fact an excess is always good to be used since NaOH is cheap and can be neutralized with diluted HCl which is also cheap so you dont have to care a lot about that. In my video I used 10% excess of NaOH. If you need te equation it would be 1eq of ASA + 3eq NaOH -> 1eq Salicylate + 1eq Acetate + 3eq H2O I guess with that final sentence you mean the same reaction but using acid catalyst instead... I sure can do that and compare yields¡¡¡ I will think on doing this :D

I dont undertsand the question... The stuff you see in the 6:40 is dissolved in the same mother liquor by increasing the temp, and then it is let to crystallize :D

@@Glattuh Ohh I see. Not sure what I was thinking (this comment was 4 months ago, lol). I plan on doing this extraction so I can make some salicylic acid to make phenol. I have done it before, but I used MeOH instead of acetone. This time I think I'll use acetone.

The one you see in the video. In spanish we call them "Tarro tipo Duquesa". I still have it, crystalls are like I make them yesterday!

Hi! In 50% of the cases I base my procedures by watching other videos on YT or from papers. The other half, like in this one, I just create them myself based on my own necesities and requirements. In any case I do not create a procedure per se. If many of you are interested I may start writing them and sharing the with you people on as pdf. But for now, its too much work for very few people that is asking about it. Thanks for your comment!

Hi¡¡ What do you mean? ASA? SA? Equipment?...

Yes! Most organic solvents work, as long as they are polar

Hi abd thanks¡¡¡¡¡¡ Do you mean you want the exact procedure I performed? If so.. I dont have it in any written form... The best you can do is watch the video and taking notes of what I did and write all the procedure. You can always alterate the procedure for your own requirements :D

Nation Of Our Hobbies I will do that :) But still thanks for your reaction!

Fucking junkie.

I'm not junkie. I just want to know

Whatever you say.