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How Ultrasound Can Deactivate Parts of the Brain

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Veritasium

Veritasium

Күн бұрын

Пікірлер: 1 900
@smartereveryday
@smartereveryday 5 жыл бұрын
Dr. Shapiro is crazy good on camera. Also, I found the multi-step approach to affect the specific region of the brain to be fascinating. It feels like unlocking a box with seven different locks on it.
@bloodspilla55
@bloodspilla55 5 жыл бұрын
SmarterEveryDay Agreed. The entire process is ingenious. It takes an incredible group of minds to figure out that the solution to invasive brain surgery involves air bubbles and ultrasound.
@Kin0bii
@Kin0bii 5 жыл бұрын
Hi, Destin! Fancy seeing you here
@1DENich1
@1DENich1 5 жыл бұрын
It would be interesting to know about a resolution of this method and how sharp are edges of the medically active zone.
@fadler1688
@fadler1688 5 жыл бұрын
Everytime I read one of your comments I read it in your voice. Hahha
@SpaceSnaxxx
@SpaceSnaxxx 5 жыл бұрын
And the locks interact non-linearly and also learn and change while you're probing the circuit...
@azdgariarada
@azdgariarada 5 жыл бұрын
Tiny bubbles In the brain Make me happy Make me feel no pain
@martiddy
@martiddy 5 жыл бұрын
Salad fingers :D
@tempname8263
@tempname8263 5 жыл бұрын
Massive bubbles In my brain Will stop my life And stop the pain
@bcmly
@bcmly 5 жыл бұрын
Small air pockets In the brain Allow me to End this pain
@efehansahin2172
@efehansahin2172 5 жыл бұрын
Air bubbles air bubbles I hope you to end my struggles I have Ligma in my brain I dont wanna feel pain
@zes7215
@zes7215 5 жыл бұрын
no such thing as ma ke or not, happx nmw
@mihailazar2487
@mihailazar2487 5 жыл бұрын
"shutting down part of the brain that's causing a seizure" Oh, so we can now add a restart button to brain partitions to be used when they glitch out, employing the tried and trusted "turn it off and then back on again" method
@davidwuhrer6704
@davidwuhrer6704 5 жыл бұрын
We used to do that with electroshocks.
@deadwingdomain
@deadwingdomain 3 жыл бұрын
LMAO
@squamish4244
@squamish4244 2 ай бұрын
As if we weren't using barbaric methods with little knowledge in the past to try and treat seizures.
@toncent
@toncent 5 жыл бұрын
It sounds like there might be also a few dangers that could come with this procedure. For example as long as the barrier is open not only your specially designed viruses can pass through but also any other virus or chemical that's in your blood. I'd be interested in prof shapiros take on the drawbacks too.
@pegatrisedmice
@pegatrisedmice 5 жыл бұрын
That is literally imposible #destroyed
@kingplunger6033
@kingplunger6033 5 жыл бұрын
@@pegatrisedmice #?
@somedudeok1451
@somedudeok1451 5 жыл бұрын
Yeah, I would've liked to hear of the probably pretty severe side effects this can have. Possibly still better than cutting open the skull tho.
@lovelylychee2255
@lovelylychee2255 5 жыл бұрын
Those were like my first thoughts too, epp a scary thought.
@riperchetobg
@riperchetobg 5 жыл бұрын
I was also thinking of how likely it would be that the virus dna embeds in our own and that gets passed on to our kids.
@VaskoGames
@VaskoGames 5 жыл бұрын
"We can prevent memory formation"... oh boy this sounds kind of scary, think of all the conspiracy theories that could come from this! On the bright side I like how their purpose is to actually help people with this procedure and the level of innovation is really amazing!
@JohnSmith-lf5xm
@JohnSmith-lf5xm 5 жыл бұрын
kzfaq.info/get/bejne/oJx1mLNevLHWlJ8.html
@bassisku
@bassisku 5 жыл бұрын
Long time memory formation is way more complex, since a memory is just our brain recreating a memory. This will actually be way more useful treating seizures and other malfunctions. Especially with all the emotions etc. coming with the memory.
@neutronstar6739
@neutronstar6739 5 жыл бұрын
There is literally a person who is unable to form a memory, some say his life is like vivid memories. Every day its like a reset for him, its pretty sad.
@JohnSmith-lf5xm
@JohnSmith-lf5xm 5 жыл бұрын
kzfaq.info/get/bejne/rq5mmdBivM7UdI0.html
@dahahaka
@dahahaka 5 жыл бұрын
@@JohnSmith-lf5xm Holy crap this channel is retarded, thanks for sharing, I reported both videos and the channel
@thejesuschrist
@thejesuschrist 5 жыл бұрын
Science is so awesome! True medical miracles... I'm in awe. We are living in amazing times!
@yossifalaa8951
@yossifalaa8951 5 жыл бұрын
Hi jesus
@andriusakinis3219
@andriusakinis3219 5 жыл бұрын
Thank you jesus, very cool!
@EchoHeo
@EchoHeo 5 жыл бұрын
Hey J dawg
@rajeshdas6539
@rajeshdas6539 5 жыл бұрын
Which religion is correct according to you Jesus?
@owensquelch449
@owensquelch449 5 жыл бұрын
@@rajeshdas6539 let's be honest, jesus's doesn't care he just think were all stupid.
@judewaide8328
@judewaide8328 5 жыл бұрын
Not gonna lie that doctor looked a little crazy. WE CAN SHUT OFF THE BRAIN! *wide eyes grinning*
@yaz0333
@yaz0333 5 жыл бұрын
We need an international mouse day of some sort to celebrate all the mice that contributed to tech innovations or just ,well, experiments
@somedudeok1451
@somedudeok1451 5 жыл бұрын
Right. Cause that will make the mice feel better about it all. Lol. That's like a hunter "honoring" the animal he just killed. It's just hypocrisy to help sleep better at night.
@yaz0333
@yaz0333 5 жыл бұрын
@@somedudeok1451 Exactly my thought, you got the point
@justrinat2207
@justrinat2207 5 жыл бұрын
​@@somedudeok1451 It's hypocrisy to pretend that death isn't part of life, whether you die by a meteor or a gun shot or under a scalpel. Furthermore, no hunter is as disillusioned as you seem to be on the subject, those practices were established by countless hunters to prevent sport-hunting and wastefulness out of genuine respect for the bounty provided by nature.
@somedudeok1451
@somedudeok1451 5 жыл бұрын
@Just Rinat: You make it sound as if being bred to have weird and deadly experiments done on you is something completely natural. Now, I know it's necessery to test medicine on beings that are less valuable than humans, but I say we should not kid ourselves and think it's completely ok just because we build mouse monuments and have some international mouse day.
@tomhass8015
@tomhass8015 5 жыл бұрын
his point was obviously about your hunter comment
@jerry3790
@jerry3790 5 жыл бұрын
Three words I never thought I’d hear next to each other
@MacedonianHero
@MacedonianHero 5 жыл бұрын
ERTW
@gewurzgurke4964
@gewurzgurke4964 5 жыл бұрын
Tiny air bubbles?
@muscularbrainiac1713
@muscularbrainiac1713 5 жыл бұрын
"Non-invasive Brain Surgery" Ever heard of X-knife Surgery?
@jamief415
@jamief415 5 жыл бұрын
"It's rewind time"
@rens6374
@rens6374 5 жыл бұрын
"Fortnite and Marques Brownlee"
@quinten373
@quinten373 5 жыл бұрын
0:00 the question I ask myself everyday
@wooprime3482
@wooprime3482 5 жыл бұрын
have a reply you good sir
@markman090
@markman090 5 жыл бұрын
lol
@SopanKotbagi
@SopanKotbagi 5 жыл бұрын
Gotta love the Professor's smile and energy!!
@LuliLulu
@LuliLulu 5 жыл бұрын
He’s quite handsome too :)
@amit4Bihar
@amit4Bihar 3 жыл бұрын
He used that dopamine tech on himself
@keithwilson6060
@keithwilson6060 3 жыл бұрын
Mad scientists usually sound like that.
@deadwingdomain
@deadwingdomain 3 жыл бұрын
It's how people are programmed...
@halfaworldaway
@halfaworldaway 5 жыл бұрын
How people like Dr Shapiro can even conceive of something like this never ceases to blow my mind. ...I may need surgery for that.
@meezi8536
@meezi8536 5 жыл бұрын
Mikhail looks like one of those evil villains that's seems nice at the start.
@EnzoDraws
@EnzoDraws 5 жыл бұрын
Ah, the good ol' Disney twist villain...
@idontthinkso2431
@idontthinkso2431 5 жыл бұрын
Yeah... Why he always smiling? little bit creepy
@ConfuzzledTomato
@ConfuzzledTomato 5 жыл бұрын
@@idontthinkso2431 c'mon guys cut him some slack. May be he was smiling because he was nervous how often do you have camera shoved in your face while addressing potentially millions of general public?
@dw2843
@dw2843 5 жыл бұрын
Riandhita it’s a nervous reaction for a lot of people. I do it too.
@JorgetePanete
@JorgetePanete 5 жыл бұрын
that* seems
@Aufenthalt
@Aufenthalt 5 жыл бұрын
The idea in the whole is a puzzle of highly skilled pieces: brain-blood barrier, cavitation excitation, gene therapy and molecular neurobiology. Amazing.
@michel.b5752
@michel.b5752 4 жыл бұрын
@Aufenthalt and a not so good SciFi scenario !
@RemiDav
@RemiDav 5 жыл бұрын
My team is actually working on genomic expression influencing brain structure and ultimately behavior (addiction, risk taking, etc...). It is good to know that once we identify the genes and parts of the brain, someone will actually be able to do something about it. It is amazing !
@arzoo_singh
@arzoo_singh 4 жыл бұрын
Congrats for the great work . Now I have some questions ? 1)can we remotely do gene editing .as in using CRISPR from a distance . 2)Is their a way brain is regulating genes on and off switch ? 3)Can genes be modified to behave as some virus as we know that DNA contain information about all disease in our forefather even in humanity . 4)Can we communicate with DNA from a distance as some peole talk about DNA communicates through light .
@squamish4244
@squamish4244 3 жыл бұрын
The critical operative question is WHEN.
@aravindpallippara1577
@aravindpallippara1577 2 жыл бұрын
@@arzoo_singh thank gods the good man didn't reply and waste his time - I will though 1. Remotely? Sure if you can inject the viral vector with a remotely controlled manipulator. 2. Can brain turn genes on and off? No? Suppressing and activating genes happens when DNA copying is underway as far as I can tell - there could be some epigenome - machinery that decode dna - affected by neurotransmitters? I am just speculating here. 3. All information about diseases from forefathers? Fiction is really getting hard to you mate, AC games aren't real - the DNA contains specific adaptions that could help against certain diseases and environmental conditions, but that's from natural evolution (the ones without the adaptations died out due to the diseases). The only place where your ancestor's immunity gets transferred to you is through mother's milk (where she got it from her mother) - perhaps that's real thing you should be worried about. 4. Can DNA communicate from a distance? There is quantum entanglement - where sub atomic particles behave in accordance with one another regardless of the distance between them. Though... Um it's not unique DNA or humans or living things really - subatomic particles constitutes sun as well as stone just as it does constitute mobile phone or conspiracy theorist
@arzoo_singh
@arzoo_singh 2 жыл бұрын
@@aravindpallippara1577 I have a philisophy I reply in same manner . So you started thanks God he did not wasted his time. Who is asking for you're opinion as if anyone cared 😜..for you're opinion . Since you started in a amazing way .I never felt like even reading that.. Arrogance and idiocity should be responded in same manner .
@aangthejeweler
@aangthejeweler 5 жыл бұрын
i love how this man is always smiling, he looks so happy, and sounds like he loves his job
@whygoogle5051
@whygoogle5051 3 жыл бұрын
Kinda creepy, tbh. As if he's hiding something...
@bm-ub6zc
@bm-ub6zc 2 жыл бұрын
Veritasium commanded him: "Smile all the time while talking. People on youtube love that!"
@ChadMojito
@ChadMojito 5 жыл бұрын
OK, this is epic
@luisbreva6122
@luisbreva6122 5 жыл бұрын
Why did I know in advance someone would comment this?
@RamenMcdonald
@RamenMcdonald 5 жыл бұрын
this is epic
@damianhernandez265
@damianhernandez265 5 жыл бұрын
Alexaaa
@xTiamat
@xTiamat 5 жыл бұрын
Been Shapiro epic gamer
@RamenMcdonald
@RamenMcdonald 5 жыл бұрын
@@xTiamat Mikhail shapiro? Nah Ben shapiro epic
@halfnwhole751
@halfnwhole751 5 жыл бұрын
2:13 So basically they just scream at your brain and it makes your blood tubes move?
@moth4256
@moth4256 5 жыл бұрын
yeah, this technique is really old, parents have been using this technique to fix brains for centuries
@pattykrabbies
@pattykrabbies 5 жыл бұрын
Crander Woaaaaah
@JamesR624
@JamesR624 5 жыл бұрын
@@moth4256 Yeah but then CalTech wouldn't have an excuse to spend money and this channel wouldn't have an easy video to rack up views.
@hashali
@hashali 5 жыл бұрын
loool
@ConfuzzledTomato
@ConfuzzledTomato 5 жыл бұрын
@@JamesR624 whoosh
@DrDothraki
@DrDothraki 5 жыл бұрын
I'm a medical student and finally something from veritasium that I can understand word by word!
@joeshmoe978
@joeshmoe978 5 жыл бұрын
This is one of the most fascinating videos I have seen in my entire life, the possibilities seem endless.
@orion1995
@orion1995 5 жыл бұрын
They did surgery on a brain
@axelandersson6314
@axelandersson6314 5 жыл бұрын
Toxinize First off, they didn't. Second off, the point is that they won't.
@opsoc777
@opsoc777 5 жыл бұрын
@@axelandersson6314 Woosh
@axelandersson6314
@axelandersson6314 5 жыл бұрын
OP's OC No, you twat, I am very well aware of this cancerous meme.
@Profanitey
@Profanitey 5 жыл бұрын
Axel Andersson r/woosh
@axelandersson6314
@axelandersson6314 5 жыл бұрын
I would formally like to appeal to a higher court to overturn this opinion that I missed the joke.
@TommoCarroll
@TommoCarroll 5 жыл бұрын
That may have been the most beautiful thumbnail I've seen on KZfaq. Congrats Derek, YOU'VE DONE IT! 🙌🙌🙌
@codekillerz5392
@codekillerz5392 5 жыл бұрын
Aspect Science Hey, I’m subscribed to you
@TommoCarroll
@TommoCarroll 5 жыл бұрын
@@codekillerz5392 well hey there :)
@veritasium
@veritasium 5 жыл бұрын
Aspect Science haha I’m finally hiring people who make things that look a lot better than I could do...
@TommoCarroll
@TommoCarroll 5 жыл бұрын
@@veritasium haha, well hat's off to them! And hey, if you're looking to work with someone that makes _different_ looking animations to you I'd love to chat about making a video together!
@TomasPetkevicius94
@TomasPetkevicius94 5 жыл бұрын
And we met once again Aspect Science, third time now. Your all over youtube.
@Gvb123
@Gvb123 3 жыл бұрын
I suffer from cluster cefalea and chronic migraine and this MIGHT be the best thing i've ever heard so far. I already had an invasive surgery (2 Neurostimulators on two nerves of my face connected to a battery pack on my chest lol) but had them removed since the "cure" was worst than the sickness. I really hope this guy achieves his goal. It'd be a life-changing matter for people like me.
@Wieprzow
@Wieprzow 5 жыл бұрын
6:43 oh boi, that smile never lies
@charlesgiraffe8138
@charlesgiraffe8138 5 жыл бұрын
A veritasium Upload? This day’s already amazing
@JorgetePanete
@JorgetePanete 5 жыл бұрын
day's* Veritasium upload*
@Ascii89
@Ascii89 5 жыл бұрын
What do you mean 'already'? It's 9pm here 😒
@ChrisKogos
@ChrisKogos 5 жыл бұрын
*Ben Shapiro joke*
@salmonjoseph9970
@salmonjoseph9970 5 жыл бұрын
Well at least his brother is actually using facts and logic hahaha!
@massimookissed1023
@massimookissed1023 5 жыл бұрын
Ben Shapiro *_IS_* the joke.
@pegatrisedmice
@pegatrisedmice 5 жыл бұрын
This is not a meme video, *Chris*
@fawndoe1917
@fawndoe1917 5 жыл бұрын
@John Smith Damn, facts didn't care about his feelings
@amfm4087
@amfm4087 5 жыл бұрын
:dab:
@10PHILMCRUCH01
@10PHILMCRUCH01 5 жыл бұрын
I love how excited that scientist gets talking about what they hope to use the technology for
@bm-ub6zc
@bm-ub6zc 2 жыл бұрын
Veritasium commanded the doctor: "Smile all the time while talking. People on youtube love that!"
@NicoKupfer
@NicoKupfer 5 жыл бұрын
Derek, I love your videos very very much, but this one was too short! What an INCREDIBLE technology (sounds like science fiction but isn't). I hope you are well :) Get a rest and have a nice Christmas! (Down an Internet rabbithole I go!)
@Yashodhan1917
@Yashodhan1917 4 жыл бұрын
You sound like my professors, are you one?
@rayus77
@rayus77 5 жыл бұрын
Quick Question : What if we could open up the entire blood brain barrier, insert the virus into the prefrontal cortex to turn all the neurons into drug receptors and selectively feed the drug to induce reversible memory loss. Sounds dystopian !.
@valeriobertoncello1809
@valeriobertoncello1809 5 жыл бұрын
Sounds exactly like a Black Mirror episode
@hahahano2796
@hahahano2796 5 жыл бұрын
That's because it is. This is essentially a genetic on/off switch that can be localized. The obvious examples being bodily immobilization (motor control) or lobotomization (frontal cortex). Although, it can get even "better". Targeting other structures of the brain can lead to someone who is overcome with fear all the time or someone who has uncontrollable anger. But hey, no "scientists" ever seem to ask themselves "should we do this" after thinking of a possible way to do something. Good ole' CRISPR.
@pluto8404
@pluto8404 5 жыл бұрын
@@hahahano2796 so women with an off switch. That will be a wonderful day.
@hahahano2796
@hahahano2796 5 жыл бұрын
@@pluto8404 , Because women are those who are complained about and demonized all the time in the mainstream, amirite?
@Adam-cq2yo
@Adam-cq2yo 5 жыл бұрын
@@hahahano2796 Dystopian novel, here I come!
@lordsincross
@lordsincross 5 жыл бұрын
People like this guy should get so much more attention... And hopefully funding. I mean, just a second or two before he mentioned depression I thought just about that. There are so many people in the world just waiting for something like this so that they can get their lives back... Just the prospect of it, brings tears to my eyes
@leachasson6775
@leachasson6775 5 жыл бұрын
Hi, I am not a doctor or in medecin so I have few questions about that technic : 1) if the "curative" virus (viral vector in the video from 2:30) can enter in the brain, any other virus could pass, no ? 2) In that case those virus, not genetically modified, could grow and spread in the brain. Mice have a short life so a unwanted virus in their brain might not be discovered during their life even it entered during the experiment ? How could we check that ? Only with animal with a longer life ? 3) Isn't it too dangerous to open a blood barriere in the brain ? Is there a way to let pass only the viral vector and not another virus ? Regards, Lea
@saumitrachakravarty
@saumitrachakravarty 5 жыл бұрын
Checking if there is any unwanted virus in blood before the procedure is easy and pretty standard. Routine checks are done to exclude common infections prior to any surgical procedure. And don't worry! Blood inside your blood vessels generally is free from any kind of pathogen, thanks to our immune system.
@skullcrushers1000
@skullcrushers1000 5 жыл бұрын
Science wins again.
@leachasson6775
@leachasson6775 5 жыл бұрын
Thanks ;)
@saumitrachakravarty
@saumitrachakravarty 5 жыл бұрын
@@yesno1498 Thanks for asking. Immune system, acquired immunity to be precise, cannot destroy any new microbe right away. It needs about two weeks to prepare biological weapons against it once detected. So, the modified virus would have done their job, that is to transfer codes for new receptors into brain cells, long before they are intercepted and neutralized.
@user-oc6ky2tk5o
@user-oc6ky2tk5o 5 жыл бұрын
@@saumitrachakravarty so what if there is a new virus in your bloodstream, which is not detected during the check up ?
@solventman8307
@solventman8307 5 жыл бұрын
Did you tried to turn it off and on?
@Adam-cq2yo
@Adam-cq2yo 5 жыл бұрын
@@lekrakkenz2517 /r/woosh
@lekrakkenz2517
@lekrakkenz2517 5 жыл бұрын
Adam r/doublewoosh
@sdm000
@sdm000 5 жыл бұрын
@@lekrakkenz2517 r/whooshh
@opsoc777
@opsoc777 5 жыл бұрын
These keys are opening up some pretty big gates...
@underpowerjet
@underpowerjet 5 жыл бұрын
Wow, Blood Brain Barrier is one of the hardest problems in current medicine. Majority of the medicine that currently exists is unable to pass through BBB because how good the filtering process the BBB has! This is amazing if it can work on humans! One of the biggest long standing challenge has a possible solution.
@Ksilisab
@Ksilisab 5 жыл бұрын
That Shapiro guy has some cool nostrils
@MrStarnger1
@MrStarnger1 5 жыл бұрын
He nose his field well
@alveolate
@alveolate 5 жыл бұрын
he's got an amazing smell- i mean smile.
@ZeroRelevance
@ZeroRelevance 5 жыл бұрын
some may say they are... epic
@SirFaceFone
@SirFaceFone 5 жыл бұрын
and a cute smile
@MassiveAchievement
@MassiveAchievement 5 жыл бұрын
hey, i watch your videos.
@XavierMaire1
@XavierMaire1 5 жыл бұрын
This is amazing. Like, REALLY amazing. Meanwhile, some people still think the earth is flat.
@pararera6394
@pararera6394 5 жыл бұрын
Do Brain Surgery on guys who comment "First", "second" etc… :D
@technobabble7702
@technobabble7702 5 жыл бұрын
FiRSt
@malvoliomaximillian2001
@malvoliomaximillian2001 5 жыл бұрын
@@technobabble7702 do they even have a brain
@DuelMaster60
@DuelMaster60 5 жыл бұрын
finally someone with good ideas
@shivamjaiswal439
@shivamjaiswal439 5 жыл бұрын
*That implies they've a brain*
@rajeshdas6539
@rajeshdas6539 5 жыл бұрын
*_-Sixty ninth-_*
@Im2Old4ThisShite
@Im2Old4ThisShite 3 жыл бұрын
FYI from an MRI tech. The "squeaking" is the pump that circulates liquid helium around the "magnet" for cooling.
@kaselier1116
@kaselier1116 5 жыл бұрын
I'm not usually in to medical stuff but this is quite possibly the coolest thing i have ever seen on the internet.
@zeratulrus142
@zeratulrus142 5 жыл бұрын
Shutting down someone's ability to remember stuff for a certain amount of time gives some... interesting possibilities, that we probably don't want anyone to have. Advancements in brain surgeries can be really helpful though.
@whychoooseausername4763
@whychoooseausername4763 5 жыл бұрын
It would be much harder to do with memories that are important for humans, than mice trying to remember a location. There are a lot of different types of memory (episodic, semantic, working, short term) that are stored in different areas of the brain, and a single memory's different aspects are shared among different areas that shift over time and with attempts at recall.
@Todestuete
@Todestuete 5 жыл бұрын
Dude there's tons of drugs to restrict memory build up. Roofies, alcohol,... No need to send me sth as complicated.
@zeratulrus142
@zeratulrus142 5 жыл бұрын
@@Todestuete yeah, but alcohol has other effects that can lead to a person not doing anything remotely close to what they were supposed to do. And you need quite a lot of it to achieve it, so those side effects will be noticeable.
@framegrace1
@framegrace1 5 жыл бұрын
I'm sure they are not after that for humans. They just do memory disabling because is easy to test in mice. It's mentioned briefly in the video that they want to be able to "shut off parts of the brain". That will be very effective for epilepsy or parkinson for example
@BluefuelSystemsH2ogas
@BluefuelSystemsH2ogas 5 жыл бұрын
@@whychoooseausername4763 ?
@AFOPatches
@AFOPatches 5 жыл бұрын
Uhhh why is the dude behind the door at 5:50 only moving at like 5 frames per second? Glitch in the matrix
@1980rlquinn
@1980rlquinn 5 жыл бұрын
What are you talking about? That's the reflection of the other dude and he's just chillin'. Might check your own comp for hiccoughs.
@zuhairmehdee
@zuhairmehdee 5 жыл бұрын
omg you're right wtffff
@LuisCasstle
@LuisCasstle 5 жыл бұрын
Not behind but a reflection. But yes still glitchy AF.
@medsaib9149
@medsaib9149 5 жыл бұрын
KZfaq video compression.. heard of that ?
@AFOPatches
@AFOPatches 5 жыл бұрын
@@medsaib9149 It's obviously video compression homie im not retarded
@brebeeb
@brebeeb 5 жыл бұрын
that is such cool research, my goodness turning off seizures or depression would be revolutionary
@adityabankar
@adityabankar 5 жыл бұрын
I was constantly smiling while watching this video. I think that the doctor was able to influence my brain remotely ☺️
@quill444
@quill444 5 жыл бұрын
With continuing, ongoing, episodic trigeminal neuralgia pain for forty-six years now, I would volunteer as a human research subject if this could reduce mandibular nerve pain. - j q t -
@IceMetalPunk
@IceMetalPunk 5 жыл бұрын
This is some of the most exciting research I've heard of in a long time! Targeting specific regions of the brain for treatments is one of the hardest problems we have, and this would, at least somewhat, solve that without any surgery needed. I'm going to keep my eye out on Professor Shapiro and his work! I likely won't have a better treatment for my depression in my own lifetime, but maybe in the future, people won't have to suffer like I have
@squamish4244
@squamish4244 3 жыл бұрын
Neurofeedback.
@Lucas-gs7sk
@Lucas-gs7sk 3 жыл бұрын
Came in fearing mind control left feeling hopeful for the future of science and medicine
@7abtaingaming683
@7abtaingaming683 5 жыл бұрын
How do you get rid of the air bubbles? and how can you prevent them from combining into larger bubbles and causing an Air embolism?
@BeastRo
@BeastRo 5 жыл бұрын
The real question is: Could this be done on a GRAPE??
@obi-wankenobi9871
@obi-wankenobi9871 5 жыл бұрын
No, grapes are way too complex for this procedure.
@Argoon1981
@Argoon1981 5 жыл бұрын
no your brain is to much complex... :P
@GvinahGui
@GvinahGui 5 жыл бұрын
The day they do a brain surgery on a grape it will be the greatest achievement of mankind
@nineten9011
@nineten9011 5 жыл бұрын
What about a mango or blue berry
@TrollinJoker
@TrollinJoker 5 жыл бұрын
Grapes will always member
@daftheck1439
@daftheck1439 5 жыл бұрын
THIS SMILE! He just used that science to stimulate his dopamine production, or he's on drug x)
@shabarish2727
@shabarish2727 5 жыл бұрын
Or , say , for a second , he is happy that years of research have led to limelight by a major youtuber and he will gain more traction and finds
@daftheck1439
@daftheck1439 5 жыл бұрын
@@shabarish2727 you're certainly right captain but it doesn't matter! THIS SMILE on it's own is much more than that smile you're talking about :)
@nonmater
@nonmater 5 жыл бұрын
I know you don't know me, but I hope you know that you're saving me during a life-changing trip. Thank you, Veritasium. You're a good, wholesome thing in the world. Love, Non.
@chriswilliams8159
@chriswilliams8159 5 жыл бұрын
This is pretty cool and revolutionary,considering how frightening surgeries can be for some people with high risk probabilities.
@FD87
@FD87 5 жыл бұрын
Scientist: We'll introduce viruses into the brain, but instead of replicating their DNA, it'll replicate the DNA we want. Me: This is how the zombie apocalypse starts.
@pigeonpower42
@pigeonpower42 5 жыл бұрын
They wouldn't be able to pass it on to other people though.
@manuvillada5697
@manuvillada5697 5 жыл бұрын
Think about brain enhancement... The future will be interesting
@bassisku
@bassisku 5 жыл бұрын
Sadly from a biological perspective this is far fetched. It's like saying dropping a ball could reverse gravity if you did it too many times.
@epiccoffeedrinker3961
@epiccoffeedrinker3961 5 жыл бұрын
LoL🤣🤣
@manuvillada5697
@manuvillada5697 5 жыл бұрын
Wooo imagine not contagious zombies that you can turn on by sound. Just hide the virus and micro-bubbles inside a vaccine. Then on a special day in a specific event play the right music and boooom!! The crowd eats the president.
@serpentine1983
@serpentine1983 5 жыл бұрын
This reminds me of the movie Star Trek: The Voyage Home. McCoy: My God man, drilling holes in his head is not the answer! The artery must be repaired! Now, put away your butcher's knives and let me save this patient before it's too late! Nice advancement.
@hullgatt
@hullgatt 5 жыл бұрын
What a time to be alive! Can't wait until I get to do some research. Thanks for the information!
@paulb6436
@paulb6436 7 ай бұрын
Did you see the latest 60 minutes. Huge segment on this with people. Amazing stuff. Love you channel.
@coscorrodrift
@coscorrodrift 5 жыл бұрын
Ok, this is epic
@mossm717
@mossm717 5 жыл бұрын
What about the risk of other viruses crossing the barrier? And how is this reversible?
@manuvillada5697
@manuvillada5697 5 жыл бұрын
I was thinking the same. There is probably a risk of infection, and it doesn't sound reversible. Still super promising :)
@whychoooseausername4763
@whychoooseausername4763 5 жыл бұрын
It only lasts a couple of seconds.
@arifhossain9751
@arifhossain9751 5 жыл бұрын
Not all viruses are deadly though. And some are programmable, so you can make them die after they've done their job.
@obi-wankenobi9871
@obi-wankenobi9871 5 жыл бұрын
You have to make sure the persons blood is free of anything that could damage the brain before the treatment.
@Nj1498
@Nj1498 5 жыл бұрын
The virii don't contain their own RNA any more. They are modified to have the sequence required and they replicate that inserted sequence.
@rileycardiff1583
@rileycardiff1583 5 жыл бұрын
So incredible in the way technology advances so quickly
@saqibmudabbar
@saqibmudabbar 5 жыл бұрын
I worked on something similar back in 2010, it’s called non invasive ultrasound therapy, developed by a company called Haifu in Chongqing, China. They used this technology on people with Breast cancer and other tumors. It was so accurate that you could point it to individual cancer cells, one by one. It destroyed them by transducing ultrasonic waves focused a few inches deep into the tissue. The waves would vibrate the malignant cells to heat them up until they exploded, kinda like how the microwave works except that microwave uses electromagnetic waves. Coolest thing I have ever worked on. I think this is an application of that technology. Very cool!
@kalashchangal170
@kalashchangal170 5 жыл бұрын
What do you think about brain computer interface
@TommoCarroll
@TommoCarroll 5 жыл бұрын
The idea of brain computer interfaces is something I'm really intrigued by! I haven't done any research into the area yet, but the idea of essentially taking out the middle-man of eg a sensory organ between a stimulus and your brain is fascinating!
@arifhossain9751
@arifhossain9751 5 жыл бұрын
True (Full Dive) Virtual Reality is something I wanna work on some day...
@user-tb4bs9po9b
@user-tb4bs9po9b 5 жыл бұрын
Ok this is epic
@Eric0728
@Eric0728 3 жыл бұрын
This seems incredibly important to actually try and tease apart what a particular neurotransmitter in a particular pathway influences. Modern pysch treatments are pretty scattershot. Unregulated dopamine everywhere instead of a particular pathway that needs to be effected.
@Infaviored
@Infaviored 5 жыл бұрын
This makes me proud to be a human. It was also extremely well presented and the person interviewed was so friendly. What would be a reason to dislike such a video. I am really curious.
@helenanevrayeva
@helenanevrayeva 5 жыл бұрын
I'm curious about how can only certain molecules enter the brain and not the unwanted ones if you open the blood-brain barrier? Does it have to do with having other types of barriers other than tight junctures, like special proteins for example? If that is the case, can "real" viruses, that are similar to the ones that have been specifically modified in the lab, pass as them and enter the brain?
@whychoooseausername4763
@whychoooseausername4763 5 жыл бұрын
The idea is open the blood barrier for a short amount of time and absolutely flood the biggest accessible artery supplying that area with huge amounts of the drug or virus you want to administer, so as to maximize the amount of desired product going in and leave as little time as possible for the unwanted molecules to pass through. I don't know the details of the molecular biology (it doesn't have to do with special transporters though) or how they measure the passage of unwanted stuff into the brain.
@helenanevrayeva
@helenanevrayeva 5 жыл бұрын
@@whychoooseausername4763 Oh thanks! That makes sense. I should look into it :)
@whychoooseausername4763
@whychoooseausername4763 5 жыл бұрын
@@helenanevrayeva Please feel free to educate me if you do ! I read a scientific article about this technology a couple of years ago when it first came out, but I haven't kept up with the research :)
@raresmircea
@raresmircea 5 жыл бұрын
That must surely deserve to be called the Rube-Goldberg procedure.
@roadfart5537
@roadfart5537 5 жыл бұрын
Professor Shapiro's passion for his work radiates throughout his being. It's so much fun to see/hear an explanation from somebody who is clearly so excited about the work their doing. Great selection, and also, well done with the visualizations (3D), Alan Chamberlain. It really demonstrated the mechanism that he was explaining, at least, for the layman such as myself.
@sultan9j572
@sultan9j572 3 жыл бұрын
If we do not support such innovation, it is impossible for us to progress as human beings. In everything in the world there is great harm, but sometimes the benefit is greater. I really liked the professor's smile
@feynstein1004
@feynstein1004 5 жыл бұрын
While this is nothing short of amazing, I find the fact that we can replace the DNA in neurons in such large scales to be much more important. If DNA modification in such scales is possible, then surely all the cellular damage caused by aging is not only treatable but also reversible. This could be the cure for aging.
@ohokcool
@ohokcool 5 жыл бұрын
CRISPR-cas9 viruses do that better, that's more likely to be your aging cure. The blood brain barrier is the only reason we couldn't do this to brain cells before this advancement. Did you know you can buy CRISPR-cas9 viruses and vectors online?? $8.50 per microgram
@feynstein1004
@feynstein1004 5 жыл бұрын
@NO I did know about CRISPR-cas9 but I didn't know they were that cheap. Though I wouldn't know how to use it, or what even to do with it tbh. So not very useful 😂
@N0M4dIC1RST
@N0M4dIC1RST 5 жыл бұрын
@@feynstein1004 check The Odin. Crazy guy there doing a lot to make genetic engineering accessible.
@cobalius
@cobalius 5 жыл бұрын
Nah i don't think about stopping aging. I think about alzheimer and dying more authentically once we can treat its causes.
@feynstein1004
@feynstein1004 5 жыл бұрын
@Tasty Rainbro Eh don't we know about its causes already? Some kind of plaque buildup in the brain?
@dudamoos
@dudamoos 5 жыл бұрын
This sounds really useful but also really scary. Also, as a diver, introducing any kinds of bubbles into my blood stream makes me uncomfortable (even so called "micro bubbles" are carefully controlled when determining safe bottom times). That sounds like it's asking for trouble.
@ManWithBeard1990
@ManWithBeard1990 5 жыл бұрын
Ooh, for my master's thesis we're using the exact same MRI scanner, only with a PET insert in it for hybrid imaging.
@itsnotyasir
@itsnotyasir 5 жыл бұрын
I like his absurdly big and cheesy smile😂😂
@sandepten
@sandepten 5 жыл бұрын
Wow this will revolutionize our world
@bassisku
@bassisku 5 жыл бұрын
Very promising, but making it cheaper and readily available will be difficult and take years. It will take minimum of 10 years until we get a viable commercial procedure. So just in time we get older.
@99897767
@99897767 5 жыл бұрын
Your world? What about MY world! I live in the Nth dimensions, please send help
@roboticpro8727
@roboticpro8727 5 жыл бұрын
Go to OpenWater.cc, Their technology is based on this, we are in exciting times indeed, this is one of the things that has future implications for VR aswell.
@majapahitsumatra5771
@majapahitsumatra5771 3 жыл бұрын
Why dr. Shapiro feels like future super villain who's trying to hide some weird experiments he's doing with a smile??
@Salehalanazi-7
@Salehalanazi-7 5 жыл бұрын
This guy is a genius, Good luck with your work brother!
@tismon112
@tismon112 5 жыл бұрын
You pointed the camera at the mri when talking about the ultrasound, making it appear as if you were confusing the MRI for an ultrasound.
@superuno312
@superuno312 5 жыл бұрын
inb4 this becomes mind control in 20 years
@michel.b5752
@michel.b5752 4 жыл бұрын
@casual Don't worry, this is only a fake feeding a conspiracy theory.
@maxpayne438
@maxpayne438 5 жыл бұрын
Darpa guys are wetting their pants
@aaronkoch3273
@aaronkoch3273 5 жыл бұрын
I was thinking the same thing.. Imagine: Grab somebody off the street, inhibit their memory formation, 'interrogate' them for hours, drop them in a hotel, and they wouldn't even remember it. Yikes.
@davidwuhrer6704
@davidwuhrer6704 5 жыл бұрын
@@aaronkoch3273 It wouldn't work like that. First you would need to get them into one of those MRI tubes. Then you have to wait a while while the virus rewrites the neuroreceptors. And only then can you administer the chosen drug that will inhibit memory creation. So your subjects will remember the abduction and the time in the MRI tube. No way around that with this method. And that is not what it's for. There are many much simpler and easier ways to inhibit memory creation, and even implanting of false memories.
@medness3915
@medness3915 5 жыл бұрын
I am a medical student dreaming to become a neurosurgeon and this is so intersting to me. I will follow with extreme interest every progress of this research. I took many notes listening this scientist and so many ideas are flowing in my head now :D Thank You! P.S.: excuse my english, I am italian xD
@andrewfortmusic
@andrewfortmusic 2 жыл бұрын
I saw some people concerned about the modified virus and thought I’d address that: Under normal circumstances, yes, the virus would replicate and spread throughout the brain. But viruses don’t spread like we’d think they do-rather than dividing to reproduce and attacking cells like a bacterium would, they hijack cells by injecting new genetic material that forces them to make new viruses. The reason this is bad is because, in most instances, this process eventually kills the cell-the viruses are not expelled and they will collect inside the cell membrane until the cell bursts. But, since these experimental viruses have already been hijacked and coded, they only inject the new DNA as designed and do not force the cell to replicate the virus. All this does is adds a new bit of genetic code into the neurons to cause them to develop the new receptors.
@Zenobeus
@Zenobeus 5 жыл бұрын
5:47 What's with the lower frame rate of the guy in the reflection to the left?
@mayankkr.246
@mayankkr.246 5 жыл бұрын
*X files soundtrack intensifies*
@bp56789
@bp56789 5 жыл бұрын
Different guy?
@yatint9665
@yatint9665 5 жыл бұрын
696 likes, 0 dislikes. Well that says something. Edit: 719 likes, 1 dislike Edit 2: 760 likes, 1 dislike Edit 3: 781:1 Edit 4, 820:1
@tengun
@tengun 5 жыл бұрын
Every time I see something this fascinating, I feel like the world is developing too fast, and that I'm old already.
@unknown9106
@unknown9106 5 жыл бұрын
The motivation aspect of the technology is going to put human advancement at a crazy level
@OldClam5
@OldClam5 5 жыл бұрын
Another great video by Derk of Veristablium! Thanks mate.
@mike.308
@mike.308 5 жыл бұрын
"It's not non-invasive brain surgery." Doesn't have quite the same ring to it...
@shresthabageshwar2254
@shresthabageshwar2254 5 жыл бұрын
Thank you veritasium,very cool.
@Puharesource
@Puharesource 5 жыл бұрын
I like how happy this guy is sharing his work, you can really tell he cares about the work him and his team is doing!
@bachlamtung5131
@bachlamtung5131 5 жыл бұрын
Wow that’s amazing!
@ktsk2031
@ktsk2031 5 жыл бұрын
This is amazing! I'm interested about their study design. I'm sure it's very thorough but I would hope that for the mouse control group they still put them through similar process as placebo (ie: being subjected to the loud noises of the MRI, undergoing the ultrasound and injection of material). Just to eliminate the possibility that the test group mice didn't fail the memory task due to the mental trauma they'd endured!
@XXLoderunnerXX
@XXLoderunnerXX 5 жыл бұрын
I hope this gets to a working stage for people. My life would be changed forever thanks to it. :)
@commie563
@commie563 5 жыл бұрын
We are going to be immortal one day.
@fgnoyola
@fgnoyola 5 жыл бұрын
Not we... someone else will... not you...
@chuffy-t3272
@chuffy-t3272 5 жыл бұрын
I think he's implying that "we" means the human race.
@fgnoyola
@fgnoyola 5 жыл бұрын
@@chuffy-t3272 Obviously, and I'm just being pessimistic, its not a bad thing to be reminded that regardless we all belong to the same species, individuality matters as well, "we" is meaningless with an "I'...
@eat_ze_bugs
@eat_ze_bugs 5 жыл бұрын
6:36 The military probably has already done it.
@Iancreed8592
@Iancreed8592 5 жыл бұрын
Can block you from remembering something? So I could watch the most amazing movie ever over and over and over again and never get tired? Right on.
@Rajat-Sharma1
@Rajat-Sharma1 5 жыл бұрын
I just dont understand why this channel has only 5 million subscribers 🤔
@ANTHONY09PRIEST
@ANTHONY09PRIEST 5 жыл бұрын
If they wanted mice not to form memories they could have just given them some booze :-)
@davidwuhrer6704
@davidwuhrer6704 5 жыл бұрын
Of course. But the point is not to prevent memory formation. That was just to test if the technique works in principle. Now they can go on to heal things booze can't.
@EnderVolt589
@EnderVolt589 5 жыл бұрын
Tbh as time goes on, sci-fi becomes more and more a reality
@xMDawg19x
@xMDawg19x 5 жыл бұрын
This is incredible. Something straight out of Star Trek. In 40 years, we're going to look back on open brain surgery and think we were so primitive as a society.
@davidwuhrer6704
@davidwuhrer6704 5 жыл бұрын
Don't look down on our ancestors. They made today possible.
@nick2629
@nick2629 5 жыл бұрын
Ok, this is epic.
@AurelienGeron
@AurelienGeron 5 жыл бұрын
+Veritasium, great video, as always, thanks! I recommend you watch this fascinating talk by Mickael Tanter: kzfaq.info/get/bejne/nrZphLCK17uzdX0.html . He is one of the inventors of functional ultrasound imaging (fUS): a high-resolution & high-speed imaging technique based on ultrasound and nano-bubbles, it's quite amazing. Perhaps even worth a video?
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