Dr. Shapiro is crazy good on camera. Also, I found the multi-step approach to affect the specific region of the brain to be fascinating. It feels like unlocking a box with seven different locks on it.
@bloodspilla555 жыл бұрын
SmarterEveryDay Agreed. The entire process is ingenious. It takes an incredible group of minds to figure out that the solution to invasive brain surgery involves air bubbles and ultrasound.
@Kin0bii5 жыл бұрын
Hi, Destin! Fancy seeing you here
@1DENich15 жыл бұрын
It would be interesting to know about a resolution of this method and how sharp are edges of the medically active zone.
@fadler16885 жыл бұрын
Everytime I read one of your comments I read it in your voice. Hahha
@SpaceSnaxxx5 жыл бұрын
And the locks interact non-linearly and also learn and change while you're probing the circuit...
@azdgariarada5 жыл бұрын
Tiny bubbles In the brain Make me happy Make me feel no pain
@martiddy5 жыл бұрын
Salad fingers :D
@tempname82635 жыл бұрын
Massive bubbles In my brain Will stop my life And stop the pain
@bcmly5 жыл бұрын
Small air pockets In the brain Allow me to End this pain
@efehansahin21725 жыл бұрын
Air bubbles air bubbles I hope you to end my struggles I have Ligma in my brain I dont wanna feel pain
@zes72155 жыл бұрын
no such thing as ma ke or not, happx nmw
@mihailazar24875 жыл бұрын
"shutting down part of the brain that's causing a seizure" Oh, so we can now add a restart button to brain partitions to be used when they glitch out, employing the tried and trusted "turn it off and then back on again" method
@davidwuhrer67045 жыл бұрын
We used to do that with electroshocks.
@deadwingdomain3 жыл бұрын
LMAO
@squamish42442 ай бұрын
As if we weren't using barbaric methods with little knowledge in the past to try and treat seizures.
@toncent5 жыл бұрын
It sounds like there might be also a few dangers that could come with this procedure. For example as long as the barrier is open not only your specially designed viruses can pass through but also any other virus or chemical that's in your blood. I'd be interested in prof shapiros take on the drawbacks too.
@pegatrisedmice5 жыл бұрын
That is literally imposible #destroyed
@kingplunger60335 жыл бұрын
@@pegatrisedmice #?
@somedudeok14515 жыл бұрын
Yeah, I would've liked to hear of the probably pretty severe side effects this can have. Possibly still better than cutting open the skull tho.
@lovelylychee22555 жыл бұрын
Those were like my first thoughts too, epp a scary thought.
@riperchetobg5 жыл бұрын
I was also thinking of how likely it would be that the virus dna embeds in our own and that gets passed on to our kids.
@VaskoGames5 жыл бұрын
"We can prevent memory formation"... oh boy this sounds kind of scary, think of all the conspiracy theories that could come from this! On the bright side I like how their purpose is to actually help people with this procedure and the level of innovation is really amazing!
@JohnSmith-lf5xm5 жыл бұрын
kzfaq.info/get/bejne/oJx1mLNevLHWlJ8.html
@bassisku5 жыл бұрын
Long time memory formation is way more complex, since a memory is just our brain recreating a memory. This will actually be way more useful treating seizures and other malfunctions. Especially with all the emotions etc. coming with the memory.
@neutronstar67395 жыл бұрын
There is literally a person who is unable to form a memory, some say his life is like vivid memories. Every day its like a reset for him, its pretty sad.
@JohnSmith-lf5xm5 жыл бұрын
kzfaq.info/get/bejne/rq5mmdBivM7UdI0.html
@dahahaka5 жыл бұрын
@@JohnSmith-lf5xm Holy crap this channel is retarded, thanks for sharing, I reported both videos and the channel
@thejesuschrist5 жыл бұрын
Science is so awesome! True medical miracles... I'm in awe. We are living in amazing times!
@yossifalaa89515 жыл бұрын
Hi jesus
@andriusakinis32195 жыл бұрын
Thank you jesus, very cool!
@EchoHeo5 жыл бұрын
Hey J dawg
@rajeshdas65395 жыл бұрын
Which religion is correct according to you Jesus?
@owensquelch4495 жыл бұрын
@@rajeshdas6539 let's be honest, jesus's doesn't care he just think were all stupid.
@judewaide83285 жыл бұрын
Not gonna lie that doctor looked a little crazy. WE CAN SHUT OFF THE BRAIN! *wide eyes grinning*
@yaz03335 жыл бұрын
We need an international mouse day of some sort to celebrate all the mice that contributed to tech innovations or just ,well, experiments
@somedudeok14515 жыл бұрын
Right. Cause that will make the mice feel better about it all. Lol. That's like a hunter "honoring" the animal he just killed. It's just hypocrisy to help sleep better at night.
@yaz03335 жыл бұрын
@@somedudeok1451 Exactly my thought, you got the point
@justrinat22075 жыл бұрын
@@somedudeok1451 It's hypocrisy to pretend that death isn't part of life, whether you die by a meteor or a gun shot or under a scalpel. Furthermore, no hunter is as disillusioned as you seem to be on the subject, those practices were established by countless hunters to prevent sport-hunting and wastefulness out of genuine respect for the bounty provided by nature.
@somedudeok14515 жыл бұрын
@Just Rinat: You make it sound as if being bred to have weird and deadly experiments done on you is something completely natural. Now, I know it's necessery to test medicine on beings that are less valuable than humans, but I say we should not kid ourselves and think it's completely ok just because we build mouse monuments and have some international mouse day.
@tomhass80155 жыл бұрын
his point was obviously about your hunter comment
@jerry37905 жыл бұрын
Three words I never thought I’d hear next to each other
@MacedonianHero5 жыл бұрын
ERTW
@gewurzgurke49645 жыл бұрын
Tiny air bubbles?
@muscularbrainiac17135 жыл бұрын
"Non-invasive Brain Surgery" Ever heard of X-knife Surgery?
@jamief4155 жыл бұрын
"It's rewind time"
@rens63745 жыл бұрын
"Fortnite and Marques Brownlee"
@quinten3735 жыл бұрын
0:00 the question I ask myself everyday
@wooprime34825 жыл бұрын
have a reply you good sir
@markman0905 жыл бұрын
lol
@SopanKotbagi5 жыл бұрын
Gotta love the Professor's smile and energy!!
@LuliLulu5 жыл бұрын
He’s quite handsome too :)
@amit4Bihar3 жыл бұрын
He used that dopamine tech on himself
@keithwilson60603 жыл бұрын
Mad scientists usually sound like that.
@deadwingdomain3 жыл бұрын
It's how people are programmed...
@halfaworldaway5 жыл бұрын
How people like Dr Shapiro can even conceive of something like this never ceases to blow my mind. ...I may need surgery for that.
@meezi85365 жыл бұрын
Mikhail looks like one of those evil villains that's seems nice at the start.
@EnzoDraws5 жыл бұрын
Ah, the good ol' Disney twist villain...
@idontthinkso24315 жыл бұрын
Yeah... Why he always smiling? little bit creepy
@ConfuzzledTomato5 жыл бұрын
@@idontthinkso2431 c'mon guys cut him some slack. May be he was smiling because he was nervous how often do you have camera shoved in your face while addressing potentially millions of general public?
@dw28435 жыл бұрын
Riandhita it’s a nervous reaction for a lot of people. I do it too.
@JorgetePanete5 жыл бұрын
that* seems
@Aufenthalt5 жыл бұрын
The idea in the whole is a puzzle of highly skilled pieces: brain-blood barrier, cavitation excitation, gene therapy and molecular neurobiology. Amazing.
@michel.b57524 жыл бұрын
@Aufenthalt and a not so good SciFi scenario !
@RemiDav5 жыл бұрын
My team is actually working on genomic expression influencing brain structure and ultimately behavior (addiction, risk taking, etc...). It is good to know that once we identify the genes and parts of the brain, someone will actually be able to do something about it. It is amazing !
@arzoo_singh4 жыл бұрын
Congrats for the great work . Now I have some questions ? 1)can we remotely do gene editing .as in using CRISPR from a distance . 2)Is their a way brain is regulating genes on and off switch ? 3)Can genes be modified to behave as some virus as we know that DNA contain information about all disease in our forefather even in humanity . 4)Can we communicate with DNA from a distance as some peole talk about DNA communicates through light .
@squamish42443 жыл бұрын
The critical operative question is WHEN.
@aravindpallippara15772 жыл бұрын
@@arzoo_singh thank gods the good man didn't reply and waste his time - I will though 1. Remotely? Sure if you can inject the viral vector with a remotely controlled manipulator. 2. Can brain turn genes on and off? No? Suppressing and activating genes happens when DNA copying is underway as far as I can tell - there could be some epigenome - machinery that decode dna - affected by neurotransmitters? I am just speculating here. 3. All information about diseases from forefathers? Fiction is really getting hard to you mate, AC games aren't real - the DNA contains specific adaptions that could help against certain diseases and environmental conditions, but that's from natural evolution (the ones without the adaptations died out due to the diseases). The only place where your ancestor's immunity gets transferred to you is through mother's milk (where she got it from her mother) - perhaps that's real thing you should be worried about. 4. Can DNA communicate from a distance? There is quantum entanglement - where sub atomic particles behave in accordance with one another regardless of the distance between them. Though... Um it's not unique DNA or humans or living things really - subatomic particles constitutes sun as well as stone just as it does constitute mobile phone or conspiracy theorist
@arzoo_singh2 жыл бұрын
@@aravindpallippara1577 I have a philisophy I reply in same manner . So you started thanks God he did not wasted his time. Who is asking for you're opinion as if anyone cared 😜..for you're opinion . Since you started in a amazing way .I never felt like even reading that.. Arrogance and idiocity should be responded in same manner .
@aangthejeweler5 жыл бұрын
i love how this man is always smiling, he looks so happy, and sounds like he loves his job
@whygoogle50513 жыл бұрын
Kinda creepy, tbh. As if he's hiding something...
@bm-ub6zc2 жыл бұрын
Veritasium commanded him: "Smile all the time while talking. People on youtube love that!"
@ChadMojito5 жыл бұрын
OK, this is epic
@luisbreva61225 жыл бұрын
Why did I know in advance someone would comment this?
@RamenMcdonald5 жыл бұрын
this is epic
@damianhernandez2655 жыл бұрын
Alexaaa
@xTiamat5 жыл бұрын
Been Shapiro epic gamer
@RamenMcdonald5 жыл бұрын
@@xTiamat Mikhail shapiro? Nah Ben shapiro epic
@halfnwhole7515 жыл бұрын
2:13 So basically they just scream at your brain and it makes your blood tubes move?
@moth42565 жыл бұрын
yeah, this technique is really old, parents have been using this technique to fix brains for centuries
@pattykrabbies5 жыл бұрын
Crander Woaaaaah
@JamesR6245 жыл бұрын
@@moth4256 Yeah but then CalTech wouldn't have an excuse to spend money and this channel wouldn't have an easy video to rack up views.
@hashali5 жыл бұрын
loool
@ConfuzzledTomato5 жыл бұрын
@@JamesR624 whoosh
@DrDothraki5 жыл бұрын
I'm a medical student and finally something from veritasium that I can understand word by word!
@joeshmoe9785 жыл бұрын
This is one of the most fascinating videos I have seen in my entire life, the possibilities seem endless.
@orion19955 жыл бұрын
They did surgery on a brain
@axelandersson63145 жыл бұрын
Toxinize First off, they didn't. Second off, the point is that they won't.
@opsoc7775 жыл бұрын
@@axelandersson6314 Woosh
@axelandersson63145 жыл бұрын
OP's OC No, you twat, I am very well aware of this cancerous meme.
@Profanitey5 жыл бұрын
Axel Andersson r/woosh
@axelandersson63145 жыл бұрын
I would formally like to appeal to a higher court to overturn this opinion that I missed the joke.
@TommoCarroll5 жыл бұрын
That may have been the most beautiful thumbnail I've seen on KZfaq. Congrats Derek, YOU'VE DONE IT! 🙌🙌🙌
@codekillerz53925 жыл бұрын
Aspect Science Hey, I’m subscribed to you
@TommoCarroll5 жыл бұрын
@@codekillerz5392 well hey there :)
@veritasium5 жыл бұрын
Aspect Science haha I’m finally hiring people who make things that look a lot better than I could do...
@TommoCarroll5 жыл бұрын
@@veritasium haha, well hat's off to them! And hey, if you're looking to work with someone that makes _different_ looking animations to you I'd love to chat about making a video together!
@TomasPetkevicius945 жыл бұрын
And we met once again Aspect Science, third time now. Your all over youtube.
@Gvb1233 жыл бұрын
I suffer from cluster cefalea and chronic migraine and this MIGHT be the best thing i've ever heard so far. I already had an invasive surgery (2 Neurostimulators on two nerves of my face connected to a battery pack on my chest lol) but had them removed since the "cure" was worst than the sickness. I really hope this guy achieves his goal. It'd be a life-changing matter for people like me.
@Wieprzow5 жыл бұрын
6:43 oh boi, that smile never lies
@charlesgiraffe81385 жыл бұрын
A veritasium Upload? This day’s already amazing
@JorgetePanete5 жыл бұрын
day's* Veritasium upload*
@Ascii895 жыл бұрын
What do you mean 'already'? It's 9pm here 😒
@ChrisKogos5 жыл бұрын
*Ben Shapiro joke*
@salmonjoseph99705 жыл бұрын
Well at least his brother is actually using facts and logic hahaha!
@massimookissed10235 жыл бұрын
Ben Shapiro *_IS_* the joke.
@pegatrisedmice5 жыл бұрын
This is not a meme video, *Chris*
@fawndoe19175 жыл бұрын
@John Smith Damn, facts didn't care about his feelings
@amfm40875 жыл бұрын
:dab:
@10PHILMCRUCH015 жыл бұрын
I love how excited that scientist gets talking about what they hope to use the technology for
@bm-ub6zc2 жыл бұрын
Veritasium commanded the doctor: "Smile all the time while talking. People on youtube love that!"
@NicoKupfer5 жыл бұрын
Derek, I love your videos very very much, but this one was too short! What an INCREDIBLE technology (sounds like science fiction but isn't). I hope you are well :) Get a rest and have a nice Christmas! (Down an Internet rabbithole I go!)
@Yashodhan19174 жыл бұрын
You sound like my professors, are you one?
@rayus775 жыл бұрын
Quick Question : What if we could open up the entire blood brain barrier, insert the virus into the prefrontal cortex to turn all the neurons into drug receptors and selectively feed the drug to induce reversible memory loss. Sounds dystopian !.
@valeriobertoncello18095 жыл бұрын
Sounds exactly like a Black Mirror episode
@hahahano27965 жыл бұрын
That's because it is. This is essentially a genetic on/off switch that can be localized. The obvious examples being bodily immobilization (motor control) or lobotomization (frontal cortex). Although, it can get even "better". Targeting other structures of the brain can lead to someone who is overcome with fear all the time or someone who has uncontrollable anger. But hey, no "scientists" ever seem to ask themselves "should we do this" after thinking of a possible way to do something. Good ole' CRISPR.
@pluto84045 жыл бұрын
@@hahahano2796 so women with an off switch. That will be a wonderful day.
@hahahano27965 жыл бұрын
@@pluto8404 , Because women are those who are complained about and demonized all the time in the mainstream, amirite?
@Adam-cq2yo5 жыл бұрын
@@hahahano2796 Dystopian novel, here I come!
@lordsincross5 жыл бұрын
People like this guy should get so much more attention... And hopefully funding. I mean, just a second or two before he mentioned depression I thought just about that. There are so many people in the world just waiting for something like this so that they can get their lives back... Just the prospect of it, brings tears to my eyes
@leachasson67755 жыл бұрын
Hi, I am not a doctor or in medecin so I have few questions about that technic : 1) if the "curative" virus (viral vector in the video from 2:30) can enter in the brain, any other virus could pass, no ? 2) In that case those virus, not genetically modified, could grow and spread in the brain. Mice have a short life so a unwanted virus in their brain might not be discovered during their life even it entered during the experiment ? How could we check that ? Only with animal with a longer life ? 3) Isn't it too dangerous to open a blood barriere in the brain ? Is there a way to let pass only the viral vector and not another virus ? Regards, Lea
@saumitrachakravarty5 жыл бұрын
Checking if there is any unwanted virus in blood before the procedure is easy and pretty standard. Routine checks are done to exclude common infections prior to any surgical procedure. And don't worry! Blood inside your blood vessels generally is free from any kind of pathogen, thanks to our immune system.
@skullcrushers10005 жыл бұрын
Science wins again.
@leachasson67755 жыл бұрын
Thanks ;)
@saumitrachakravarty5 жыл бұрын
@@yesno1498 Thanks for asking. Immune system, acquired immunity to be precise, cannot destroy any new microbe right away. It needs about two weeks to prepare biological weapons against it once detected. So, the modified virus would have done their job, that is to transfer codes for new receptors into brain cells, long before they are intercepted and neutralized.
@user-oc6ky2tk5o5 жыл бұрын
@@saumitrachakravarty so what if there is a new virus in your bloodstream, which is not detected during the check up ?
@solventman83075 жыл бұрын
Did you tried to turn it off and on?
@Adam-cq2yo5 жыл бұрын
@@lekrakkenz2517 /r/woosh
@lekrakkenz25175 жыл бұрын
Adam r/doublewoosh
@sdm0005 жыл бұрын
@@lekrakkenz2517 r/whooshh
@opsoc7775 жыл бұрын
These keys are opening up some pretty big gates...
@underpowerjet5 жыл бұрын
Wow, Blood Brain Barrier is one of the hardest problems in current medicine. Majority of the medicine that currently exists is unable to pass through BBB because how good the filtering process the BBB has! This is amazing if it can work on humans! One of the biggest long standing challenge has a possible solution.
@Ksilisab5 жыл бұрын
That Shapiro guy has some cool nostrils
@MrStarnger15 жыл бұрын
He nose his field well
@alveolate5 жыл бұрын
he's got an amazing smell- i mean smile.
@ZeroRelevance5 жыл бұрын
some may say they are... epic
@SirFaceFone5 жыл бұрын
and a cute smile
@MassiveAchievement5 жыл бұрын
hey, i watch your videos.
@XavierMaire15 жыл бұрын
This is amazing. Like, REALLY amazing. Meanwhile, some people still think the earth is flat.
@pararera63945 жыл бұрын
Do Brain Surgery on guys who comment "First", "second" etc… :D
@technobabble77025 жыл бұрын
FiRSt
@malvoliomaximillian20015 жыл бұрын
@@technobabble7702 do they even have a brain
@DuelMaster605 жыл бұрын
finally someone with good ideas
@shivamjaiswal4395 жыл бұрын
*That implies they've a brain*
@rajeshdas65395 жыл бұрын
*_-Sixty ninth-_*
@Im2Old4ThisShite3 жыл бұрын
FYI from an MRI tech. The "squeaking" is the pump that circulates liquid helium around the "magnet" for cooling.
@kaselier11165 жыл бұрын
I'm not usually in to medical stuff but this is quite possibly the coolest thing i have ever seen on the internet.
@zeratulrus1425 жыл бұрын
Shutting down someone's ability to remember stuff for a certain amount of time gives some... interesting possibilities, that we probably don't want anyone to have. Advancements in brain surgeries can be really helpful though.
@whychoooseausername47635 жыл бұрын
It would be much harder to do with memories that are important for humans, than mice trying to remember a location. There are a lot of different types of memory (episodic, semantic, working, short term) that are stored in different areas of the brain, and a single memory's different aspects are shared among different areas that shift over time and with attempts at recall.
@Todestuete5 жыл бұрын
Dude there's tons of drugs to restrict memory build up. Roofies, alcohol,... No need to send me sth as complicated.
@zeratulrus1425 жыл бұрын
@@Todestuete yeah, but alcohol has other effects that can lead to a person not doing anything remotely close to what they were supposed to do. And you need quite a lot of it to achieve it, so those side effects will be noticeable.
@framegrace15 жыл бұрын
I'm sure they are not after that for humans. They just do memory disabling because is easy to test in mice. It's mentioned briefly in the video that they want to be able to "shut off parts of the brain". That will be very effective for epilepsy or parkinson for example
@BluefuelSystemsH2ogas5 жыл бұрын
@@whychoooseausername4763 ?
@AFOPatches5 жыл бұрын
Uhhh why is the dude behind the door at 5:50 only moving at like 5 frames per second? Glitch in the matrix
@1980rlquinn5 жыл бұрын
What are you talking about? That's the reflection of the other dude and he's just chillin'. Might check your own comp for hiccoughs.
@zuhairmehdee5 жыл бұрын
omg you're right wtffff
@LuisCasstle5 жыл бұрын
Not behind but a reflection. But yes still glitchy AF.
@medsaib91495 жыл бұрын
KZfaq video compression.. heard of that ?
@AFOPatches5 жыл бұрын
@@medsaib9149 It's obviously video compression homie im not retarded
@brebeeb5 жыл бұрын
that is such cool research, my goodness turning off seizures or depression would be revolutionary
@adityabankar5 жыл бұрын
I was constantly smiling while watching this video. I think that the doctor was able to influence my brain remotely ☺️
@quill4445 жыл бұрын
With continuing, ongoing, episodic trigeminal neuralgia pain for forty-six years now, I would volunteer as a human research subject if this could reduce mandibular nerve pain. - j q t -
@IceMetalPunk5 жыл бұрын
This is some of the most exciting research I've heard of in a long time! Targeting specific regions of the brain for treatments is one of the hardest problems we have, and this would, at least somewhat, solve that without any surgery needed. I'm going to keep my eye out on Professor Shapiro and his work! I likely won't have a better treatment for my depression in my own lifetime, but maybe in the future, people won't have to suffer like I have
@squamish42443 жыл бұрын
Neurofeedback.
@Lucas-gs7sk3 жыл бұрын
Came in fearing mind control left feeling hopeful for the future of science and medicine
@7abtaingaming6835 жыл бұрын
How do you get rid of the air bubbles? and how can you prevent them from combining into larger bubbles and causing an Air embolism?
@BeastRo5 жыл бұрын
The real question is: Could this be done on a GRAPE??
@obi-wankenobi98715 жыл бұрын
No, grapes are way too complex for this procedure.
@Argoon19815 жыл бұрын
no your brain is to much complex... :P
@GvinahGui5 жыл бұрын
The day they do a brain surgery on a grape it will be the greatest achievement of mankind
@nineten90115 жыл бұрын
What about a mango or blue berry
@TrollinJoker5 жыл бұрын
Grapes will always member
@daftheck14395 жыл бұрын
THIS SMILE! He just used that science to stimulate his dopamine production, or he's on drug x)
@shabarish27275 жыл бұрын
Or , say , for a second , he is happy that years of research have led to limelight by a major youtuber and he will gain more traction and finds
@daftheck14395 жыл бұрын
@@shabarish2727 you're certainly right captain but it doesn't matter! THIS SMILE on it's own is much more than that smile you're talking about :)
@nonmater5 жыл бұрын
I know you don't know me, but I hope you know that you're saving me during a life-changing trip. Thank you, Veritasium. You're a good, wholesome thing in the world. Love, Non.
@chriswilliams81595 жыл бұрын
This is pretty cool and revolutionary,considering how frightening surgeries can be for some people with high risk probabilities.
@FD875 жыл бұрын
Scientist: We'll introduce viruses into the brain, but instead of replicating their DNA, it'll replicate the DNA we want. Me: This is how the zombie apocalypse starts.
@pigeonpower425 жыл бұрын
They wouldn't be able to pass it on to other people though.
@manuvillada56975 жыл бұрын
Think about brain enhancement... The future will be interesting
@bassisku5 жыл бұрын
Sadly from a biological perspective this is far fetched. It's like saying dropping a ball could reverse gravity if you did it too many times.
@epiccoffeedrinker39615 жыл бұрын
LoL🤣🤣
@manuvillada56975 жыл бұрын
Wooo imagine not contagious zombies that you can turn on by sound. Just hide the virus and micro-bubbles inside a vaccine. Then on a special day in a specific event play the right music and boooom!! The crowd eats the president.
@serpentine19835 жыл бұрын
This reminds me of the movie Star Trek: The Voyage Home. McCoy: My God man, drilling holes in his head is not the answer! The artery must be repaired! Now, put away your butcher's knives and let me save this patient before it's too late! Nice advancement.
@hullgatt5 жыл бұрын
What a time to be alive! Can't wait until I get to do some research. Thanks for the information!
@paulb64367 ай бұрын
Did you see the latest 60 minutes. Huge segment on this with people. Amazing stuff. Love you channel.
@coscorrodrift5 жыл бұрын
Ok, this is epic
@mossm7175 жыл бұрын
What about the risk of other viruses crossing the barrier? And how is this reversible?
@manuvillada56975 жыл бұрын
I was thinking the same. There is probably a risk of infection, and it doesn't sound reversible. Still super promising :)
@whychoooseausername47635 жыл бұрын
It only lasts a couple of seconds.
@arifhossain97515 жыл бұрын
Not all viruses are deadly though. And some are programmable, so you can make them die after they've done their job.
@obi-wankenobi98715 жыл бұрын
You have to make sure the persons blood is free of anything that could damage the brain before the treatment.
@Nj14985 жыл бұрын
The virii don't contain their own RNA any more. They are modified to have the sequence required and they replicate that inserted sequence.
@rileycardiff15835 жыл бұрын
So incredible in the way technology advances so quickly
@saqibmudabbar5 жыл бұрын
I worked on something similar back in 2010, it’s called non invasive ultrasound therapy, developed by a company called Haifu in Chongqing, China. They used this technology on people with Breast cancer and other tumors. It was so accurate that you could point it to individual cancer cells, one by one. It destroyed them by transducing ultrasonic waves focused a few inches deep into the tissue. The waves would vibrate the malignant cells to heat them up until they exploded, kinda like how the microwave works except that microwave uses electromagnetic waves. Coolest thing I have ever worked on. I think this is an application of that technology. Very cool!
@kalashchangal1705 жыл бұрын
What do you think about brain computer interface
@TommoCarroll5 жыл бұрын
The idea of brain computer interfaces is something I'm really intrigued by! I haven't done any research into the area yet, but the idea of essentially taking out the middle-man of eg a sensory organ between a stimulus and your brain is fascinating!
@arifhossain97515 жыл бұрын
True (Full Dive) Virtual Reality is something I wanna work on some day...
@user-tb4bs9po9b5 жыл бұрын
Ok this is epic
@Eric07283 жыл бұрын
This seems incredibly important to actually try and tease apart what a particular neurotransmitter in a particular pathway influences. Modern pysch treatments are pretty scattershot. Unregulated dopamine everywhere instead of a particular pathway that needs to be effected.
@Infaviored5 жыл бұрын
This makes me proud to be a human. It was also extremely well presented and the person interviewed was so friendly. What would be a reason to dislike such a video. I am really curious.
@helenanevrayeva5 жыл бұрын
I'm curious about how can only certain molecules enter the brain and not the unwanted ones if you open the blood-brain barrier? Does it have to do with having other types of barriers other than tight junctures, like special proteins for example? If that is the case, can "real" viruses, that are similar to the ones that have been specifically modified in the lab, pass as them and enter the brain?
@whychoooseausername47635 жыл бұрын
The idea is open the blood barrier for a short amount of time and absolutely flood the biggest accessible artery supplying that area with huge amounts of the drug or virus you want to administer, so as to maximize the amount of desired product going in and leave as little time as possible for the unwanted molecules to pass through. I don't know the details of the molecular biology (it doesn't have to do with special transporters though) or how they measure the passage of unwanted stuff into the brain.
@helenanevrayeva5 жыл бұрын
@@whychoooseausername4763 Oh thanks! That makes sense. I should look into it :)
@whychoooseausername47635 жыл бұрын
@@helenanevrayeva Please feel free to educate me if you do ! I read a scientific article about this technology a couple of years ago when it first came out, but I haven't kept up with the research :)
@raresmircea5 жыл бұрын
That must surely deserve to be called the Rube-Goldberg procedure.
@roadfart55375 жыл бұрын
Professor Shapiro's passion for his work radiates throughout his being. It's so much fun to see/hear an explanation from somebody who is clearly so excited about the work their doing. Great selection, and also, well done with the visualizations (3D), Alan Chamberlain. It really demonstrated the mechanism that he was explaining, at least, for the layman such as myself.
@sultan9j5723 жыл бұрын
If we do not support such innovation, it is impossible for us to progress as human beings. In everything in the world there is great harm, but sometimes the benefit is greater. I really liked the professor's smile
@feynstein10045 жыл бұрын
While this is nothing short of amazing, I find the fact that we can replace the DNA in neurons in such large scales to be much more important. If DNA modification in such scales is possible, then surely all the cellular damage caused by aging is not only treatable but also reversible. This could be the cure for aging.
@ohokcool5 жыл бұрын
CRISPR-cas9 viruses do that better, that's more likely to be your aging cure. The blood brain barrier is the only reason we couldn't do this to brain cells before this advancement. Did you know you can buy CRISPR-cas9 viruses and vectors online?? $8.50 per microgram
@feynstein10045 жыл бұрын
@NO I did know about CRISPR-cas9 but I didn't know they were that cheap. Though I wouldn't know how to use it, or what even to do with it tbh. So not very useful 😂
@N0M4dIC1RST5 жыл бұрын
@@feynstein1004 check The Odin. Crazy guy there doing a lot to make genetic engineering accessible.
@cobalius5 жыл бұрын
Nah i don't think about stopping aging. I think about alzheimer and dying more authentically once we can treat its causes.
@feynstein10045 жыл бұрын
@Tasty Rainbro Eh don't we know about its causes already? Some kind of plaque buildup in the brain?
@dudamoos5 жыл бұрын
This sounds really useful but also really scary. Also, as a diver, introducing any kinds of bubbles into my blood stream makes me uncomfortable (even so called "micro bubbles" are carefully controlled when determining safe bottom times). That sounds like it's asking for trouble.
@ManWithBeard19905 жыл бұрын
Ooh, for my master's thesis we're using the exact same MRI scanner, only with a PET insert in it for hybrid imaging.
@itsnotyasir5 жыл бұрын
I like his absurdly big and cheesy smile😂😂
@sandepten5 жыл бұрын
Wow this will revolutionize our world
@bassisku5 жыл бұрын
Very promising, but making it cheaper and readily available will be difficult and take years. It will take minimum of 10 years until we get a viable commercial procedure. So just in time we get older.
@998977675 жыл бұрын
Your world? What about MY world! I live in the Nth dimensions, please send help
@roboticpro87275 жыл бұрын
Go to OpenWater.cc, Their technology is based on this, we are in exciting times indeed, this is one of the things that has future implications for VR aswell.
@majapahitsumatra57713 жыл бұрын
Why dr. Shapiro feels like future super villain who's trying to hide some weird experiments he's doing with a smile??
@Salehalanazi-75 жыл бұрын
This guy is a genius, Good luck with your work brother!
@tismon1125 жыл бұрын
You pointed the camera at the mri when talking about the ultrasound, making it appear as if you were confusing the MRI for an ultrasound.
@superuno3125 жыл бұрын
inb4 this becomes mind control in 20 years
@michel.b57524 жыл бұрын
@casual Don't worry, this is only a fake feeding a conspiracy theory.
@maxpayne4385 жыл бұрын
Darpa guys are wetting their pants
@aaronkoch32735 жыл бұрын
I was thinking the same thing.. Imagine: Grab somebody off the street, inhibit their memory formation, 'interrogate' them for hours, drop them in a hotel, and they wouldn't even remember it. Yikes.
@davidwuhrer67045 жыл бұрын
@@aaronkoch3273 It wouldn't work like that. First you would need to get them into one of those MRI tubes. Then you have to wait a while while the virus rewrites the neuroreceptors. And only then can you administer the chosen drug that will inhibit memory creation. So your subjects will remember the abduction and the time in the MRI tube. No way around that with this method. And that is not what it's for. There are many much simpler and easier ways to inhibit memory creation, and even implanting of false memories.
@medness39155 жыл бұрын
I am a medical student dreaming to become a neurosurgeon and this is so intersting to me. I will follow with extreme interest every progress of this research. I took many notes listening this scientist and so many ideas are flowing in my head now :D Thank You! P.S.: excuse my english, I am italian xD
@andrewfortmusic2 жыл бұрын
I saw some people concerned about the modified virus and thought I’d address that: Under normal circumstances, yes, the virus would replicate and spread throughout the brain. But viruses don’t spread like we’d think they do-rather than dividing to reproduce and attacking cells like a bacterium would, they hijack cells by injecting new genetic material that forces them to make new viruses. The reason this is bad is because, in most instances, this process eventually kills the cell-the viruses are not expelled and they will collect inside the cell membrane until the cell bursts. But, since these experimental viruses have already been hijacked and coded, they only inject the new DNA as designed and do not force the cell to replicate the virus. All this does is adds a new bit of genetic code into the neurons to cause them to develop the new receptors.
@Zenobeus5 жыл бұрын
5:47 What's with the lower frame rate of the guy in the reflection to the left?
Every time I see something this fascinating, I feel like the world is developing too fast, and that I'm old already.
@unknown91065 жыл бұрын
The motivation aspect of the technology is going to put human advancement at a crazy level
@OldClam55 жыл бұрын
Another great video by Derk of Veristablium! Thanks mate.
@mike.3085 жыл бұрын
"It's not non-invasive brain surgery." Doesn't have quite the same ring to it...
@shresthabageshwar22545 жыл бұрын
Thank you veritasium,very cool.
@Puharesource5 жыл бұрын
I like how happy this guy is sharing his work, you can really tell he cares about the work him and his team is doing!
@bachlamtung51315 жыл бұрын
Wow that’s amazing!
@ktsk20315 жыл бұрын
This is amazing! I'm interested about their study design. I'm sure it's very thorough but I would hope that for the mouse control group they still put them through similar process as placebo (ie: being subjected to the loud noises of the MRI, undergoing the ultrasound and injection of material). Just to eliminate the possibility that the test group mice didn't fail the memory task due to the mental trauma they'd endured!
@XXLoderunnerXX5 жыл бұрын
I hope this gets to a working stage for people. My life would be changed forever thanks to it. :)
@commie5635 жыл бұрын
We are going to be immortal one day.
@fgnoyola5 жыл бұрын
Not we... someone else will... not you...
@chuffy-t32725 жыл бұрын
I think he's implying that "we" means the human race.
@fgnoyola5 жыл бұрын
@@chuffy-t3272 Obviously, and I'm just being pessimistic, its not a bad thing to be reminded that regardless we all belong to the same species, individuality matters as well, "we" is meaningless with an "I'...
@eat_ze_bugs5 жыл бұрын
6:36 The military probably has already done it.
@Iancreed85925 жыл бұрын
Can block you from remembering something? So I could watch the most amazing movie ever over and over and over again and never get tired? Right on.
@Rajat-Sharma15 жыл бұрын
I just dont understand why this channel has only 5 million subscribers 🤔
@ANTHONY09PRIEST5 жыл бұрын
If they wanted mice not to form memories they could have just given them some booze :-)
@davidwuhrer67045 жыл бұрын
Of course. But the point is not to prevent memory formation. That was just to test if the technique works in principle. Now they can go on to heal things booze can't.
@EnderVolt5895 жыл бұрын
Tbh as time goes on, sci-fi becomes more and more a reality
@xMDawg19x5 жыл бұрын
This is incredible. Something straight out of Star Trek. In 40 years, we're going to look back on open brain surgery and think we were so primitive as a society.
@davidwuhrer67045 жыл бұрын
Don't look down on our ancestors. They made today possible.
@nick26295 жыл бұрын
Ok, this is epic.
@AurelienGeron5 жыл бұрын
+Veritasium, great video, as always, thanks! I recommend you watch this fascinating talk by Mickael Tanter: kzfaq.info/get/bejne/nrZphLCK17uzdX0.html . He is one of the inventors of functional ultrasound imaging (fUS): a high-resolution & high-speed imaging technique based on ultrasound and nano-bubbles, it's quite amazing. Perhaps even worth a video?