A broad introduction into mass spectrometry-based proteomics data analysis.
Slides:
drive.google.com/file/d/1JKiI...
Chapters:
0:00 Introduction
7:46 Amino acids, peptides, and proteins
27:46 Mass spectrometry basics
01:20:44 MS/MS spectra and identification
01:34:33 Database search algorithms in three phases
02:20:31 Sequential search algorithms
02:25:56 Decoys and false discovery rate calculation
02:37:51 Protein inference: Bad, ugly, and not so good
By Prof. Dr. Lennart Martens, as part Prof. Dr. Clement's Statistical Genomics course from the Master of Science in Bioinformatics program at Ghent University.
@statomics @universiteitgent @VIBinFlanders
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