Ionization | General pharmacology

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Ionization | General pharmacology

Рет қаралды 65,716

8 жыл бұрын

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🔹 Ionization, PKa of drugs, effect on PH on drug pharmacokinetics,
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My name's Dr Apurva Popat, a medical graduate from India. I have scored 261 on USMLE Step 1 Examination. Check regularly to know about my USMLE journey! I have been teaching medical sciences since my 1st year of medical school. You can expect Productivity tips, Medical concepts, Motivational videos, Latest medical trends and medical tutoring videos from my channel.
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Пікірлер: 64

@user-hj7qu9kt2r Ай бұрын

Just want to say thank you ❤for easier and informative video Dr 😊

@cyrenefaithonda360 4 жыл бұрын

Thank you so much for doing this Dr. Apurva. This was 4 years ago but it helped me a lot in reviewing concepts in medicine for my boards in less time and in an easier way.

@Chantal_o 4 жыл бұрын

I love this video. Thank you so much you just saved me from failing my upcoming tests ❤️❤️❤️❤️❤️

@mansoor1308 4 ай бұрын

Thankyou so much, i benefited alot from this precise video lecture & the questions in the end were cherry on top. I am an anesthesia PG.

@ninachanel9 7 жыл бұрын

THANK YOU!! this helped so much!

@MUHAMMADABDULLAH-zj6qs Жыл бұрын

Well explained sir 👌

@ghaziaraheem4177 2 жыл бұрын

Excellent! A Million thanx

@sadiamaqsood4307 Жыл бұрын

No doubt very well explained.

@satyendrasahani4814 Жыл бұрын

Very informative video. Thank you 💞 bro

@abcs6755 2 жыл бұрын

simply extra suberbbb sir salute to You

@areejfatima1739 Жыл бұрын

Thank you sir...I finally understood concept of ionization....

@Arhzaa 2 жыл бұрын

best explanation ive found so far

@zubairsadiq5565 2 жыл бұрын

I have a question....I already know the concept and mechanism of this....but one question keeps on irritating me and confusing me... When we are alkalinizing urine with sodium bicarbonate, bicarbonate is trapping aspirin in tubules (refering to ion trapping process) and so aspirin is excreted....but my question is why sodium bicarbonate is not neutralising aspirin IN BLOOD when both are already present in blood? Why it has to work in urine specifically??

@savemeows 3 жыл бұрын

thanks doctor very informative. was reading kaplan pharma, and looked for ionized non ionized so confusing in kaplan... u made it simple..and also love the morphine part..now i know why addistc hate lemon juice!!! cuz it washes it out!!

@ActuallyCurious1402 7 ай бұрын

Thank youuu thank you finallly thank you

@erickmuthomi1942 2 жыл бұрын

Thank you so much

@rongerduniya1535 5 жыл бұрын

Well done ! Love From BD🇧🇩🇧🇩

@MrArjun936 2 жыл бұрын

This was the best explanation, finally able to clear this concept. Thank you sir.

@vaishnaviramakrishna265 4 жыл бұрын

Thank you so much! That was very understandable and helpful video!

@opporeno2387 11 ай бұрын

This is wonderful. Great 👍

@chegobego7930 Жыл бұрын

THANK YOIOOU

@rouaalharby2987 2 жыл бұрын

Thx

@udunnati 5 жыл бұрын

Very well explained

@pankajtomar1348 4 жыл бұрын

In 1st question how the ionisation will not affect with changes in ph.though ph and pka both are dependent on each other? Plz explain

@sathvikreddy1441 3 жыл бұрын

If ph changes by 1 unit then ionization changes by 10 units...

@anae.garcia9289 2 жыл бұрын

Thank you so much, this has been the best explanation I have found on this concept!

@onyxgan9923 5 жыл бұрын

Great job.. Impressive 😁

@shafio2 3 жыл бұрын

you have made it really easy. Thank you

@muhetahir7804 2 жыл бұрын

Thanks so much for sharing this education thanks 👍

@funkdaddy5641 3 жыл бұрын

thank you dr apurva i now understand the concept of ionisation and unionisation of drugs

@ApurvaPopat 3 жыл бұрын

😀😀😀⚕️⚕️⚕️

@petroszekarias7045 Жыл бұрын

Very nice presented and very helpful❤

@lilywhite8123 3 жыл бұрын

Thank you very much I finally understand the concept of ionization Cheers for the good work

@erinsinclair8407 3 жыл бұрын

thank you very much for thus video! i was really struggling to understand this topic but you made it so clear! Huge help!

@heerkshah 4 жыл бұрын

Really good video. Very helpful and easy to understand.

@jeevidhabalasubramaniam2341 4 жыл бұрын

Got a very good idea bro...just keep rocking.. very neat, clear simple explanation

@Gaayathrie.ponakala 5 жыл бұрын

Change of 1 scale in ph leads to 10 fold change in ionization

@Gaayathrie.ponakala 5 жыл бұрын

Then how option 2 is true

@nhienhoang7761 7 жыл бұрын

why is the phenobarbitone with pKa of 7.2 is weak acid ?

@somahiwa5416 3 жыл бұрын

why most the drug weak acid and weak baise? can you explain for me please

@perlaelbomba 6 жыл бұрын

This video was so helpful!! Thanks a lot!!

@leximassey7931 Жыл бұрын

thank you for simplifying! so helpful =)

@kirsten9729 3 жыл бұрын

THANK. YOU. SO. MUCH.

@thabisonyawo500 7 жыл бұрын

thanks alot man this helped a lot with my pharmacokinetics section

@goatsk 3 жыл бұрын

Thank you please upload more videos on ADME Of drugs

@saadiaaden8965 4 жыл бұрын

Honestly this was fantastic ❤️❤️❤️

@teaganbatis7103 6 жыл бұрын

This was so helpful thank you so much

@solid648 5 жыл бұрын

Awesome video, helped a lot.

@dharmendrakewat8336 5 жыл бұрын

Sir well explained I liked please make more and more videos

@harshalrahangdale968 4 жыл бұрын

Thanku u ...... it's a very helpful vedio

@ApurvaPopat 4 жыл бұрын

🎉🎉😀

@cattymed4419 7 жыл бұрын

Thanks

@mahnoorsajid4063 4 жыл бұрын

Need more videos

@pratibhagupta8816 4 жыл бұрын

Sir, amphetamine basic drug h to stomach me inonised ho jaegi to ye to souble hoye to ye BBB (lipid) Ko cross kese kr leta h 😵😵

@ApurvaPopat 4 жыл бұрын

The absorption doesnt only depend on whether the drug is basic or acidic. It depends on many other factors as well, gut lining, particle size route of administration etc. Just it may augment in the process of absorption.