"He has a right to say no." Yes! What a wonderful advocate he has in Mom.

I see him back there watching Super Mario Galaxy. That game was my childhood. Honestly, I think the internet is such a great thing because it makes videos of all kinds of games and tv shows available to those who need them to cope. I'm sure being able to dive into another world like that is really important in Jesse's life.

I LOVE how excited Jesse is about reading books and how happy he seems to be playing with Chris. He's such a sweet spirit

I'm glad for him that she said she wants, "quality of life for him." This is so important. It is obvious from his smile and his clapping that he is a happy person.

Wow. Simply wow. My child has this rare syndrome and he is 8 yrs old right now. He is so, so adept at picking up feelings or if someone is down. He doesn't have a huge vocabulary but he understands EVERYTHING said and he is so intuitive with others. His best friend's name happens to be Jesse and i thought that to be a huge coincidence

I love Jesse's enthusiasm!

I love learning about the different ways of people can communicate, this is really cool

This channel really shows all the cool ways there are to communicate besides verbal/signing/etc. and it’s super freaking cool. Jesse you are awesome 🤩

"Do you like going to music therapy?"... No! 🏃🏻‍♂️💨*Goes to computer 😂❤️

Can I just praise Chris for his patience & understanding for people who have disabilities he is so thoughtful for the parents & asks appropriate questions without offending them. He is an advocate for people who have disabilities who want to share their experiences to the world. I have autism & 22q11 Deletion Syndrome I have applied to be on this but heard nothing back other than that keep up the good work Chris & Alyssa.

My son is two and also has Pitt Hopkins. Thank you for sharing this.

His smile and excitement is so contagious!

Chris you are a very special person. God bless you.

Jesse is such a fun person, so engaged and emotive. He's obviously very bright. His family are the perfect people to help him thrive and it's clear that he has a great life.

This channel is such a blessing. The "Smile Though Your Heart Is Breaking" story, oh my God. (T_T) That is so sweet.

Jesse is great! He definitely knows every page of each book and knows when to turn the pages! It looks like he's not paying attention sometimes but he is! It's fantastic.

What an awesome young man, he may not have the words but he sure understand what's going on around him and seems to be such a happy person

Like Jesse, my brother doesn't have speech, he was also blinded at birth. And like Jesse, people who meet my brother a couple of times are always astonished at how much he knows and understands. Great meeting Jesse!

The “smile though your heart is breaking” story made me shed a few tears

just after few minutes of watching this video, I just feel like I want to be friends with him. I am a nurse and I use to work in Behavioral Health. Its amazing how they can express their feeling to communicate with you in their own unique way.

This has to be literally one of my favorite channels on youtube. I find myself watching so many episodes right after work. This interview was soo good.

He is beautiful 😊🙏 I just love him ❤ Jessie you are gorgeous 🥰 Love from Perth Western Australia Australia 🇦🇺

Omg I love this kid. All the kids you interview are all soo amazing but I think socializing with this kid would be so unique and such a great experience. Your so lucky to meet such awesome people.

his family is so lovely!

What a lovely smile he’s awesome

I'm happy that comments are back Jesse you are the best bro 👌

Gotta respect Chris and the work he does. Such a wholesome channel

Look at this man go!

Keep up the awesome things you do for folks like this!!

Definitely a teenager. “No.” *walks away

The mom's comment about his amount of depth, that's unfortunately such a sad fact of life. There are soooo many layers to the human mind, it's easy to think someone doesn't understand things, just because they can't communicate like we expect. It's similar to thinking someone without legs can not get from point A to point B, but they can! It's just their path to get there might be little different, and might take a little longer. We often forget that with certain disabilities. Everyone needs to be loved and understood. We all need to try harder to make connections and accommodations for those who need it most. ❤️🙏 I praise this guy for teaching us. I really do. My heart grows each time I watch these videos.

I love your passion in touching these lives bro, it’s very genuine.

Yes!!! Comments are back!!!

11:02 do u like music therapy NO THEN THE WALK OFF 🤣🤣🤣👍🏽HE KEPT IT SO REAL

Jessie is a happy boy,he's so exuberant

I just want to thankyou for making this show .... I love learning about these beautiful individuals who I think are absolutely amazing

Hi everyone: It's so nice to see you all again on KZfaq. I hope to meet you all one day. Take care and stay safe.

He has such a great personality! 😊

He repeats everything because he knows the answers and it makes him so very happy! Isn't that a wonderful gift? Imagine if life would be that wonderful for us! His brain does not tell him he just did the same thing and knows the answer....o, he feels like he just A-ced the most difficult test and is beside himself for joy! So he does it again and than he has a new book and it starts all over again. I bet he is exhausted when it is bedtime because he never lets his brain rest!

Jesse u r an amazing and sweet guy.

I adore this kid! He’s incredibly sweet and happy!

Jesse absolutely enjoyed it when you were reading his favorite books.. with him, not to him, but together! That's what he's so excited about! I love his energy!

Chris is one of a kind his voice is wonderful so clear so everyone can understand love this beautiful soul bless you chris ❤🙏🤝🙏✌️

Thank You for sharing this with me!!

I just love how Jess communicates it makes Me happy!!🤗

Oh my god he is so cute. Thank you so much for what you do.

There is defenitely dept when his mom says we dont know what is ahead and he Comes to her with a kiss

Jesse is such a sweet guy I'd love to hang out with him

Great show

I love the way he would answer and then push the pad away... 🤣 I can also relate to his love of the computer, I watch a lot of KZfaq too.

I love Jessie energy and he is adorable.

He seems intelligent but very very hyper and anxious!He’s definitely happy and intelligent though.Hopefully he will get treatment to calm his anxiety.

Jesse is absolutely good looking and handsome 😍

This is My favorite video!!

May god be with Jesse and god bless his family and god bless you Chris.

Awesome!

What a blessing to this world!

the questions I always ask myself when watching these type of video's is what type of existence is this, and is it worth it.

God bless them this was so sweet and awesome and God bless you reading this he loves you more than you could ever know Nothing you do NOTHING can make Him love you less

Blues Clues and Super Mario .... POG moment

Thank you for sharing

He's so adorable omg 😍😭❤

I hope he has a great life

What a nice boy! A pure and good soul :)

I really like this guy

As pessoas especiais ficam encantadas com você .Elas percebem que o seu interesse nelas é realmente sincero

my little brother has Pitt Hopkins as well

“Do you like going to music therapy?” “No!” [leaves] “Oh, that’s not true!” 🤣😂😅

The song Jesse chosed for his grieving mom impressed me. I always thought that inside any apparently crazy/disabled/mentally rearded person there's a sane person who knows exactly what is going on around them. Only this person can not communicate with the external world, but he's there .. In depth, as mom tell us.

He seems like a pretty smart kid to me!❤

I love this kid!

He is a sweetheart so cute

Awesome Parents 🤩👍👍👍

honestly until i watched this i never knew that understanding language being told to you and forming sentences yourself were entirely unrelated to eachother in the brain. and honestly seeing something like that is sorta cool. mostly everyone in cool in their own sorta way

My man watching Little Einsteins in the background!

God bless you✨ 💛✨

I like his manners.

I used to have a student with this condition.

Love how bro is watching veggie tales, little Einstein and Sesame street in the background

超可愛

I would love to be Jesse's friend he is very smart

I love to read books magazines papers

I love his energy but I hope that’s now what I think it is that showed up on the computer at 4:11? 🤨😂😭

Super Mario Land 2 - 6 Golden Coins! I'd love to bond with him over that, great game!

💖💖💖💖

Me not realizing the blue's clues dog was a female until now...

Hi Chris my name is John I have cerebral palsy I communicate with my iPad but I can also White sign

Ciaooo ragazzo povero in una malattia tosta però sembra per quello che vedo intelligente però nn posso dire nn conosco la situazione sei un grande ragazzo ti mando un saluto a te e tuo papà ok ciaooo

He’s a great looking guy. This just isn’t fair.

❤❤❤

What is chromosome reverse? I’ve never heard of this disorder.

This reminds me of autism.are there any connections?

You sound like Steve when you read!

👍👍

I had no idea there were so many genetically mishaps existed.

🥰🥰🥰

lol i could see super mario land 2 on his computer screen

❤❤❤😊😊😊so cute bo , to be honest

It’s interesting to see this young man communicate,but sad to see that he has to be like this.He seems anxious and almost like he has ADHD.I guess that’s one of the symptoms of his chromosomal abnormality.