Thank you for the update! That metapod mnemonic is absolute GOLD. One more thing for everyone else: all the diseases mentioned have autosomal recessive inheritance, except for Fabry disease and Hunter syndrome, which have X-linked recessive inheritance.

He killed it with that Metapod reference; i will never forget this easily forgettable disease; thank your Sir DIrty

use me as a im worried about step but dirty relieves my anxiety button

Just watched the old one yesterday but don’t mind watching it again my king

Your videos and mnemonics have gotten me a handful of points on every test I have taken in medical school. You’re the man, Dirty! Keep up the good work!

Thank you Sir from the bottom of my heart from the bottom of my heart to be so hugely helpful and impactful in student studies. I am a big fan. I am in a financial truffle right now because as you know the MLE's are very expansive especially for foreign graduates. But once I am stable enough I will definitely be providing support. Thank you Sir and please keep up this going because you might be having no idea how much helpful this is for foreign graduates who's trying to save every penny to finally be able to give this exam and your free channel is a huge impact because it doesn't drain them financially while providing excellent top notch content for free. I have the utmost RESPECT for the services that you are providing!

My study partner and I were literally talking about adding clinical finding mnemonics to your awesome video when I saw this update. Perfection!

another cool way i learn to remember which has hepatosplenomegaly in Niemann - pick dx and Tay- sac is the follow: Think about the first word as liver and the second word as spleen. Tay- sac = both short words = no hepatosplenomegaly Niemann - Pick = long first word and second word = hepatosplenomegaly

I am signing up! Because honestly you are the best! 4.99 that a starbucks latte

I cannnot begin to quantify how helpful these Dirty Medicine mnemonics are, the information just sticks in your brain after he teaches. Then you go read the chapters in the books and further consolidate. Thank you very much.

the old video is the 1st vid i watched on ur channel a few weeks ago!! thanks for updating!

MET ARYL BROken DAD(met a real broken dad) MET - metachromatic leukodystrophy ARYL - arysulfatase A def BROken - cereBROside sulfate acc D - demyelination central + peripheral A - ataxia D - dementia

One of the best! Thank you for helping me to memorize these diseases.

Great update - i was wondering how i was going to remember the clinical presentation of these diseases. Thank you! About to go look up a clip of Metapod Pokemon right now :)

You will be the reason I even have a chance sitting for boards. Thanks Dirty!

Bro is a 🐐. Just discovered the channel. I’m boutta binge all ur vids thank you

There was a "high yield question bank" question about the treatment of Gauchers. It's just exogenous glucocerebrosidase Also, I use "Hunters have clear I's 2 shoot" for the hunters.

if you aren't familiar with pokemon this is the one I came up with "sulfur has a really meta color" sulfur for arylSULFatase and cerebroside SULFATE. meta means you have to think a lot about it = CNS defects. and Color to remember that the nerves stain yellow brown. :)

Spring-boarding off your Tay-Sach mnemonic, I just wanted to connect it to the dz name - so I made the gang a bit more aggressive (and apparently cruel): "A Gang of Six small Jews kicked me in the Sach" Happy studying everyone

God bless you doc 🙏 You have been so helpful to thousands of IMG. English Guyana/ Cuba Havana medical graduate !

Much appreciated, Dirty!

The hyphen detail is brilliant thank uuuu for ever 🙏

Awesome!! Thank you sooooo much. Crazy crazy helpful!! Suggestion: Try "(in a crying voice) OMGauch, he's such a SWEET BRO" (sweet for "gluco")

The best of all time. Absolutely genius! 🎯

Thankyou, your videos are life-savers.

Thank you, Dirty!!!!!! Great take on Metapod reference!!!!!!!!

Wow, thank you so much! God Bless!❤

Thank you very much, that's gold! For non-pokemoners, I attempted to make a Game of Thrones mnemonics: Arya's brain was catastrophic: demyelinated, dementious and ataxic Arya for ARYLSULFATASE, brain for cerebrum i.e. CEREBROSIDE SULFATE, catasTROPHIC for the metachromatic leukodysTROPHY, the rest are the symptoms (all three remind of problems related to brain). Am open for better mnemonics ;)

Fantastic video (old and new both) !!! mnemonics really help in memorizing the details. Thank you so much :D

Tysm ❤ i was mixing up the enzymes for fabry and krabbe as both have the galaxy reference but then i added "bro" at the end of krabbe's mnemonic. "The Glob of GOOey Krabbe meat is out of this world, bro" Fabry: galaxy without "bro" for Alpha galactosidase Krabbe: "this world,bro" for GALACtocereBROsidase hope this helps someone

You are an amazingly cool teacher!! I love your style!

Can you please make a video explaining the ventilator settings/ waveforms? Thanks

thank you for making biochemistry bearable

Simply the best !! Thank you

Thank you so much for the videos. X marks the spot for the aggressive hunter

for those who never really got into pokémon i have for you: clumsy cerebrities ride real sulfurous & dented metallic chrome cars. clumsy=ataxia cerebrities ride=cerebroside sulfate real sulfurous=arylsulfatase A dented=dement/demyelin metallic chrome=metachromatic leukodystrophy you can imagine some old clumsy celebrity driving a car that's just as old and clunky as them (or picture a scene out of Mad Max if you at least get that pop culture reference)

Hey, thank you for all you do :)

Yes I love u and I used all your videos for step 1 and now step 2

Not familiar with Pokemon but I now feel like I know all about Metapod! Thanks!

Huge thanks as always sir..

you are seriously the best.

3:06 Where the video actually starts. Guys please help this guy as much as u can. he is a gift to all medicos anywhere in the world

Life saver!! Thankyouuu

Hey dirty can you plz make a video on glut receptors ...if possible than 🙏

This video made me join your channel! You're amazing dirty!

awesome video thanks so much!.. for gaucher.. OMG he's such a SWEET bro (to remind u its glucocerbro).. since a bunch of them have BRO in the name! again, thanks for all of your videos

I made a mnemonic "HUNT FOX" - Hunt for hunter and F for Fabry - X for xlinked recessive :) . The remaining are AR.

So glad I waited until a week before my test to care about these so I could learn them from this video :)

U deserve to be supported 👏

this is unreal your the GOAT

Once you get me to residency with these videos I will be a member lol

Thank you for the brilliant and funny video 😁

So happy! Thank you!

Thanks!

This is amazing!! Small thing but I found it a little tricky to differentiate the enzyme/accumulations for Gaucher vs Krabbe so for Gaucher I just added "sweet bro" to remind myself of the 'gluco' in glucocerebrosidase: OMGauch ... he is such a sweet bro

In First AID 2022, Huler Syndrome is listed as having a α-l-iduronidase deficiency. You have alpha-2-iduronitase listed. Are both of these enzymes correct, or did you make a typo?

Your mnemonics are also high yield can't be forgotten

the Krabbe disease mnemonic word "world" for "gala-" might get confused with "gala-" in Fabry disease also. I'd like to add that globoid cells look kind of like a brain (galacto-cerebro-sidase)

Shukriya Ustad G

OMG, you saved my day!

Thank you

'Thank you~!!

Thank You

I love you, little one. Greetings from the DR.

I was just watching the old lysosomal storage disease video, such a coincidence!

Had to pause this video to watch every single episode of Pokémon before continuing with the lesson. For science!

another hook-on is Gauche - Paper Mache - tissue paper cytoplasm.

Yay *dances in high yield* lolol

Thank you so much! I didn't know I could laugh while studying this topic :') The pokemon reference was amazing. "He can literally only say his name." Ded.

You are a legend!

Sadly am not sure about others... but no one will forget Metapod in Metachormatic leukodystrophy

Oml I adored the metapod mnemonic :)

Thanks

I don't know anything about pokemon except pikachu, but that Metapod mnemonic is great.

Can you do a video on the different types of spondyloarthropathies?

ur the goat man

Is it supposted to be be hyper or hypohiderosis in fabry disease? Edit: most often hypo and sometimes hyper.

Bruh went in on metapod! Like damn 😂😂😂

literally googled Metapod's evolution after finished this.

HAHAAHAHAHAHAHAH!!!! I just reached Metachromatic part and im dying at the reference! sooooo accurate!

The Globoid KRABBE is out of this Big Galaxy Bro.

That metapod mnemonic would make butterfree proud!

u r the best

Since Gaucher's and Metachromatic Leukodystrophy both have just BRO for the accumilation, one way to remember meta is Cerebroside *SULFATE*, just imagine a shiny metapod and pretend it is close enough to the color of sulfur

Thankssssssss !!!!!!!!

heres a mnemonic for 'HURLER" syndrome. H: Hepatosplenomegaly (enlarged liver and spleen) U: Upper airway obstruction R: Rough or coarse facial features (skeletal anomalies) L: Learning difficulties (developmental delay) E: Enzyme deficiency (alpha-L-iduronidase) R: Retinal abnormality(corneal clouding)

why did you delete your step 1 schedule?

Tnx🎉❤

BRUH JUST LET ME PASS MY BOARDS AND I WILL FUCKING JOIN UR MEMBERSHIP You've been a great help to me and I wish that every high yield concept appears in our boards.

metapod used harden! it is super effective

Thank you. I added "Oh My Gauch, hes such a Sweet Bro" to remember its Glucocerebroside, cause all the others with bro confuse me lol. I has smooth brain

Wow the best ever

Great

I love Pokémon too lolz u r seriously my type of person

Yayyyyyy!! Ecstatic

how can I pay for the membership?

my hero

Waiting!

Hey, U can use for " Krabbe disease" : CRAB with MILK sauce, BRO, is really GOOD ;)

Which mode of inheritance are they? Are all lysosomal disease autosomal recessive?