Major Histocompatibility complex | Structure | HLA

Major Histocompatibility complex | Structure | HLA | Disease associations

Рет қаралды 3,400

3 ай бұрын

This is Part 3.. we are still trying to understand the basics of immunity before we get into nuances of diseases of immune system.
Here we learn about Major Histocompatibility Complex
#ilovepathology #pathology #immunity #adaptiveimmunity #tcellreceptor #lymphocytediversity
#medicalschoolpathology #pathologymadesimple

Пікірлер: 9

@debigdogk9563 3 ай бұрын

Awesome teaching, thank you. Never a dull moment on this channel. Thank you ❤❤❤

@samina9199 3 ай бұрын

Thanks sir for part 3 I really like your Vedios😊

@anandbandavath.4333 2 ай бұрын

Thank you sir for conditional teachings❤❤❤❤

@waelfadlallah8939 3 ай бұрын

First to watch 😊

@ilovepathologyVijayPatho 3 ай бұрын

Expecting critical comment so that it's good to improve upon 😊

@waelfadlallah8939 3 ай бұрын

@@ilovepathologyVijayPatho 😅great note

@debigdogk9563 3 ай бұрын

Please when you say these conditions are associated to the respective HLA, is it that there is a mutation in these HLA that is causing these conditions or what . Please 🙏🏾 help answer. Thank you

@ilovepathologyVijayPatho 3 ай бұрын

it is a very good question! let me try to explain. lets take HLAB27 as example! as i told HLA is a system. which during development , there can be thousands of variations in the HLA genes A B C D and so on one such variation is HLA B27 ( note that this is not a MUTATION!, just another normal variation.. its found that people with this variation i.e HLAB27, have very high risk of developing ankylosing spondylitis. it DOES NOT mean , that all individuals with HLA B27 will develop ankylosing spondylitis.. there can be absolutely normal individuals too.. hope this clarifies a. It is NOT a mutation b. not everyone with that HLA will develop a particular disease, with which it is associated Good luck :-)

@debigdogk9563 3 ай бұрын

@@ilovepathologyVijayPatho Thank you so much, you’ve been very helpful. 🙏🏾🙏🏾🙏🏾🙏🏾