When I looked awhile ago I couldn't figure out how to make acetic anhydride, but now you open some new synthesis pathways for me. Thank you!
@frostchem Жыл бұрын
Glad I could help!
@michaelwerkov3438 Жыл бұрын
... you could get acetyl chloride but not acetic anydride?
@bekeneel Жыл бұрын
@@michaelwerkov3438 The anhydride is hard to get since it's used to synthesize heroin.. In small amounts it'd be in something like aspirin synthesizing kits i believe. But you can have similar results or just a little less potent with just acetic acid & some catalyst I believe. There's also a plant that you can make the anhydride of, perhaps all of it is made from plants. I find this stuff interesting, I wanna study chemistry now and learn to do acetylation of a certain product..
@hungpokchan7552 Жыл бұрын
@@michaelwerkov3438 It's normal in China... you can also get something like benzaldehyde or HBr easily and legal, but something other are extremely hard to buy with a personal ID like diethyl ether, sulfuric acid or acetone lol
@chemistryofquestionablequa6252 Жыл бұрын
@@bekeneelthe catalyst is sulfuric acid
@user-dc8fg4gc6b Жыл бұрын
Dam I'm definitely on the watchlist after coming here .......
@TaranMovies-kd8iv5 ай бұрын
hey Brother Can we Use Fractional distillation instead of Simple distillation for Better Purity?
@petevenuti7355 Жыл бұрын
Now I got to figure out how to make acetal chloride...
@EddieTheH10 ай бұрын
The sulphur chloride route might be easier for you. Simply dry distill a TCCA and sulphur mixture.
@nicholaschristodoulou576610 ай бұрын
Acetonitrile and acetic acid and hydrogen chloride gas is the most otc route to acetyl chloride
@petevenuti735510 ай бұрын
@@nicholaschristodoulou5766 ok, now how to make acetonitrile
@nicholaschristodoulou576610 ай бұрын
How about acetonitrile and acetic acidand hydrogen chloride gas to make acetyl chloride then react with sodium acetate to get acetic anhydride
@neffix6976Ай бұрын
Damn, i just wish i could get acetyl chloride....
@piroDYMSUS2 жыл бұрын
Nice dog :)
@psycronizer Жыл бұрын
for a moment I though it was a cat !
@user-bj8th8et5x11 ай бұрын
Acetyl chloride is prohibited too
@allenhonaker41072 жыл бұрын
Could I use silicone grease to grease the joints? If not please explain why not and when and why it is necessary to use acid as opposed to silicone.
@allenhonaker41072 жыл бұрын
@@c2n10 that's what I usually do. I was was just wondering if one was preferable or necessary in some experiments as opposed to others
@frostchem2 жыл бұрын
@@allenhonaker4107 It really just matters on what you're distilling/heating. Substances like HCl, Bromine, Chromyl Chloride, etc. always want to find a way to escape its container. Those substances can eat away the silicone grease. Concentrated sulfuric acid is resistant against those substances and is used as a grease when distilling/heating those substances. If the substance isn't really as reactive as the substances I listed, you could just go ahead and use silicone grease. You can correct me if I am wrong.
@allenhonaker41072 жыл бұрын
@@frostchem Thanks. That's exactly what I wanted to know. Now I'll be much more careful with what I use.😀
@petevenuti7355 Жыл бұрын
I had an explosive reaction between manganese heptoxide and silicone grease, surprised the f*** out of me .., I previously thought of silicone grease as mainly inert ...
@dapossum9495 Жыл бұрын
@@petevenuti7355 wtf were you doing with manganese heptoxide in glass lol
@stoicismxchemistry Жыл бұрын
Where did you get your chemicals for this experiment?
@frostchem Жыл бұрын
I got the anhydrous sodium acetate online and the acetyl chloride was from a local chem supplier that helps me with ordering chemicals from China.
@pritemtaki358 Жыл бұрын
Why your acetic anhydride got yellow is there a way to make it crystal clear?
@frostchem Жыл бұрын
I probably let some kind of impurity collect in the receiving flask but a normal simple distillation should be good enough to purify it. Acetic anhydride boils at 140°C so you want to collect the distillate at that temperature.
@michael636336 Жыл бұрын
The cat is heading out
@garrysekelli6776 Жыл бұрын
Was it anhydrous acetic anhydride? Or is that redundant ?
@frostchem Жыл бұрын
It's anhydrous acetic anhydride.
@garrysekelli6776 Жыл бұрын
@@frostchem is acetic anhydride always anhydrous or can you also make hydrated acetic anhydride?
@frostchem Жыл бұрын
Acetic anhydride is always anhydrous because if it gets in contact with water, it hydrolyses into acetic acid.
@djriskykut Жыл бұрын
@@garrysekelli6776 to be fair i thought the Anhydride part gave that away
@mariocraftgames Жыл бұрын
Y para cuando el antibiótico? Quiero hacer un vídeo sobre dr stone
@frostchem Жыл бұрын
I don't know how to speak Spanish but I translated your comment and it didn't really help much. The translator said that you are making a video about Dr Stone? I'm planning to start the synthesis of the antibiotic(sulfanilamide) soon and the synthesis should be done by this year.
@mariocraftgames Жыл бұрын
I use Google translate: yes, there is an anime dr stone and in one episode they make sulfanilamide, where they mix chlorosulfonic acid and acetanilide to make the antibiotic, and I'm going to make a video explaining how it would be done in reality life, but I didn't find anything on the internet and no video on youtube explaining how to do it
@frostchem Жыл бұрын
I definitely know about Dr Stone! It's my most favourite anime. There is actually a video series of a Japanese chemist synthesizing it from benzene. Here is the video of him doing the last step in the synthesis where he reacts chlorosulfonic acid and acetanilide: kzfaq.info/get/bejne/Zq6XdZhly9O3lXU.html&ab_channel=レイユール It might be very hard to understand the reaction as he is speaking in Japanese so I will also send a link to a image which shows all the steps of the synthesis: media.cheggcdn.com/study/0db/0db3b7c0-251e-4791-bf36-144986d55189/13112-21.2-2EEI1.png
@kemalk-gt7cu Жыл бұрын
Isn't acetic anhydride formed spontaneously by adding acetic acid to something? easier way
@frostchem Жыл бұрын
No, but I wish it was that easy lol.
@kemalk-gt7cu Жыл бұрын
@@frostchem What is the easiest and cheapest way?
@kemalk-gt7cu Жыл бұрын
@@frostchem I've heard that acetic anhydride is formed when acetic acid reacts with moisture in the air.
@frostchem Жыл бұрын
The cheapest and easiest way I know as of now is the reaction of sulfur monochloride and anhydrous sodium acetate. This is a video showing the method: kzfaq.info/get/bejne/hdiKaLKSnrGVgmQ.html&ab_channel=LabCoatz . Sulfur chlorides are nasty and dangerous compounds so you should only attempt doing that method if you have proper precautions and safety.
@frostchem Жыл бұрын
Acetic anhydride is basically just 2 acetic acid molecules bonded together and all the water molecules are removed. It wouldn't make any sense if you were to make an anhydride by adding water to the substance.
@aliosmankucukpacalar10 күн бұрын
Turksh translate plz
@SciDOCMBC Жыл бұрын
Acetic anhydride is no precursor to heroin. It is used to acetylate morphine into heroin. The precursor is morphine and not acetic anhydride. A precursor is a substance that can easily be converted into another without having to go through a complete synthesis. I would love to see how you convert acetic anhydride into heroin without using morphine. 😳🤪
@chemistryofquestionablequa6252 Жыл бұрын
Under the law it's considered a precursor
@EddieTheH10 ай бұрын
No, a "precursor" is any reagent used to make the final product. Nothing to do with not having to go through a complete synthesis. 🤦
@nicholaschristodoulou576610 ай бұрын
Know it alls that know nothing
@chemistryofquestionablequa62527 ай бұрын
@yourmomurmom69 depends what country you’re in
@GerManBearPig6 ай бұрын
The police sure as hell would say otherwise and their opinion is kinda more important than yours
@nicholaschristodoulou5766 Жыл бұрын
Yes please il have 5 litres please !! What 15mls!!!! Yer gona be making alot of smack with that!!!
@EddieTheH10 ай бұрын
You are aware that it has a multitude of more common uses than acetylating morphine? Also, 15mls will make quite a bit of smack.
@nicholaschristodoulou576610 ай бұрын
@@EddieTheH sure you can acetylate anthranillic acid to make methaqualone and also you can use it with phenylacetic acid and a touch of stinky pyridine to make phenyl 2 proponone that makes almost exclusively German marching powder . It burns aswell but I wouldn’t advise using it to cook food with bit stingy on the eye!
@aussie_philosopher8079 Жыл бұрын
Everybody's aware there is a MUCH easier way to do this yeah? 2 steps instead of 10.
@siko6535 Жыл бұрын
How
@kemalk-gt7cu Жыл бұрын
Can you tell me the easy way, I think it's a lie
@chemistryofquestionablequa6252 Жыл бұрын
@@kemalk-gt7cusulfur chlorides and sodium acetate is another route but sulfur chlorides smell ungodly bad. The 2 step method he's referring to is likely a ketene lamp, but ketene is insanely toxic.
@nicholaschristodoulou576610 ай бұрын
@@chemistryofquestionablequa6252 ketene Lol !!!!! If suicide is what your after
@MichaelLapore-lk9jz Жыл бұрын
Way to much h2so4 on that ground joint! Way to contaminate product!
@EddieTheH10 ай бұрын
How are you getting H2SO4 to distill at 140°C???
@nicholaschristodoulou576610 ай бұрын
I believe the acid is placed there to catch any water and make a seal at the joint