Mast Cell Activation Syndrome (MCAS): Symptoms, Diagnosis and Treatment Made Simple by Dr. Rajsree

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Күн бұрын

Dr. Rajsree Nambudripad, MD is board-certified in Internal Medicine and founder of OC Integrative Medicine in Orange County, California. In this video she explains Mast Cell Activation Syndrome, also known as MCAS. Learn why MCAS causes a myriad of symptoms and chronic multi-system inflammation. What triggers mast cells to go awry causing MCAS? Why is MCAS an elusive diagnosis? How can you make a diagnosis of MCAS? Learn about the gastrointestinal manifestations of MCAS and the relationship to SIBO, Leaky Gut, and Dysbiosis. What's the difference between MCAS and Histamine Intolerance? How do you treat MCAS? Dr. Rajsree reviews all of this and more in this comprehensive video. Please see the chapters below:
Chapters:
00:00 Introduction
03:19 What Are Mast Cells?
05:49 When Mast Cells Go Awry Causing MCAS
08:18 Many Manifestations of MCAS
11:24 MCAS is An Acquired Disorder
11:37 Triggers for MCAS
12:53 How to Diagnose MCAS
16:08 Gastrointestinal Symptoms of MCAS
16:39 SIBO
18:39 GERD
19:11 Leaky Gut
19:38 MCAS vs. Histamine Intolerance
20:52 The Gut Microbiome
22:29 High Histamine Foods
25:01 MCAS and Autonomic Dysfunction
25:39 Palpitations
25:59 Long COVID
26:18 POTS and EDS
26:46 MCAS and the Brain
27:17 Limbic System Dysfunction
27:37 MTHFR
28:42 MCAS and Hormones
29:50 Treatment for MCAS
30:58 Symptom Control
32:16 LDN
32:47 Natural Supplements
34:17 Gut Healing Supplements
36:33 Address the Root Causes
37:16 Support Detox Pathways
37:39 Other Supportive Treatments
38:37 Key Points
➡️ Watch Dr. Rajsree's video on Candida and SIFO:
• CANDIDA and SIFO (Smal...
➡️ Watch Dr. Rajsree's video on Histamine Intolerance:
• HISTAMINE INTOLERANCE:...
➡️ Watch Dr. Rajsree's video on SIBO Herbal Protocol:
• Dr. Rajsree's Herbal P...
➡️ Watch Dr. Rajsree's video on SIBO (Original Video):
• SIBO: A doctor's guid...
➡️ Watch Dr. Rajsree's video on Leaky Gut:
• A Doctor's Guide to LE...
➡️ Watch Dr. Rajsree's video on MTHFR:
• A doctor's guide to MT...
➡️ Watch Dr. Rajsree's video on Estrogen Dominance:
• A Doctor's Guide to ES...
🧡 Shop for Supplements by Dr. Rajsree:
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⭐Learn more about her practice here:
oc-integrative-medicine.com/
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This information, including but not limited to, text, graphics, images, and other material contained in this video is for informational and educational purposes only. No material in this video is intended to be a substitute for professional medical advice, diagnosis, treatment, or medical supplement approved by the Food and Drug Administration. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician. Never disregard professional medical advice or delay in seeking it because of something you viewed in this video. No physician-patient relationship is created by this video or the information provided. Furthermore, neither Rajsree Nambudripad, MD nor any contributor to this video, makes any representations, express or implied, with respect to the information provided herein or to its use.

Пікірлер: 261

@drrajsree 7 ай бұрын

Thanks for watching everyone! Please post your questions and comments below⬇, I look forward to hearing from you! To shop for any of the Supplements described in the video: 🧡dr-rajsrees-public-supplement-store.myshopify.com

@TomlinDemetriusC 7 ай бұрын

😅P😮⁰

@neerajsainidob26 7 ай бұрын

Can vitamin B9(folate/L-5-MTHF), B3, B12, ZINC, vit A, vit C, vit D, Quercetin Which of these supplements be taken in conditions like too much urination and UTI?

@amulrani5989 6 ай бұрын

❤😊😊

@HardcoreHokage-cw4uq 4 ай бұрын

amazing ,I've had urticaria for 35 years I've been to more doctors hospitals and specialists than a sickly gazelle. I've learned more from your videos than what any of them know. I have been only using antihistamines( chlorphenamine) as it's the only thing that kinda works for flare ups. But over time I was finding I was having to take 18+ tablets a day to ease symptoms. I diagnosed myself with histamine intolerance through your videos and tried diamine oxidase supplement. Now I only take one antihistamine when I get a bad flare up. I'm currently working on detox and gut rebalance and I gotta admit I feel like I've found the elixir of youth as I feel 10 years younger. All thanks to you. Thankyou so much for your effort and time masking these videos.

@mianfaizan8239 2 ай бұрын

Ghaxxuloo9 Dr d1 o🎉@@neerajsainidob26

@effigy8620 5 ай бұрын

This is the best video I have seen so far on these frustrating issues. Thank you for taking the time doc. Your depth of care in responding to comments is so appreciated too. Wish you were in my neighbourhood in Australia. We need more of you

@drrajsree 5 ай бұрын

Thanks so much for watching! 😊 I'm so glad it was helpful.

@KhaosKev999 3 ай бұрын

I developed this as an allergic reaction to the covid vaccine... I have been suffering with this for 2 y and a half. I am taking antihistamine to help and I am on low histamine diet, gluten and lacto free and no processed food but I still get symptoms from any physical effort or stress etc... my symptoms: brain Inflammation, dizziness, nausea, brain fog, confusion, disorientation, shaking, twitching, neck problems, gluten intolernace, lacto allergy intolerance and histamine intolerance. if I eat something high in histamine I get bad brain fog, panic attacks, feels like my blood pressure is going crazy.. the reactions are different depends on what I do and what I eat. mainly the brain fog is the issue that gets worse when I walk or eat more food and it gives me confusion and disorientation... I really hope that there is a fix for this.

@drrajsree 3 ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@maartjek9691 3 ай бұрын

I also got my first flare up after te covid vaccine! for two years i did not feel that much untill I got another trigger from another injection. It's so tiring to try so hard to eat clean and doing everything you can and still react to almost everything :(

@alinaion2841 2 ай бұрын

@maartjek9691 , I understand you. I'm in the same situation for 3 years. I have flares every time my body gets in contact with different triggers (meds, insect bite, viruses...).

@bajone02 2 ай бұрын

@@maartjek9691look at Tina Peers MCAS videos

@bajone02 2 ай бұрын

@@maartjek9691look at Tina Peers MCAS videos and f l c c c

@Thegeordievegan666 4 ай бұрын

I have mcas but now I have a fear of eating incase I am ill again 😔 sweet potato is the only food i will willingly eat now

@drrajsree 4 ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@MichaelMerritt 3 ай бұрын

Thank you for calling out EMF’s. That’s a very real trigger for me and it gets pretty exhausting hearing people and Dr’s not believe it’s real. They cause inflammation and trigger flares, it’s black and white for me and would be for others that experience it too.

@drrajsree 3 ай бұрын

Yes indeed! Thanks for watching.

@kimberlynormandy2690 2 ай бұрын

Also a trigger for me too. It is real thing for sure and you are not alone!

@MichaelMerritt 2 ай бұрын

@@kimberlynormandy2690 Thanks, sadly there's a growing number of us. I did discover if you google mast cell degranulation and EMF's there's a few limited studies showing EMF's do cause degranulation! As well as studies linking microglia activation in the brain. So at least some researchers agree there's a connection there. Hope more research can help better understand why some of us are affected more than others and what we can do about it. For now I just plug everything in and distance myself from strong signals (which is sometimes hard to do).

@sharon6871 7 ай бұрын

This video describes me to a "T" and have been suffering from symptoms for decades 😢 Thank you for explaining it so easily and completely ❤

@drrajsree 7 ай бұрын

I'm sorry to hear this, but hopefully this video can help bring some explanation to your symptoms! Thanks so much for watching! 😊

@neerajsainidob26 7 ай бұрын

@@drrajsree Can vitamin B9(folate/L-5-MTHF), B3, B12, ZINC, vit A, vit C, vit D, Quercetin Which of these supplements be taken in conditions like too much urination and UTI?

@selenegold7041 7 ай бұрын

Just...wow! Informative, concise, easy to understand, thorough. You deserve an award!! Thank you for all of your research, time and editing. You've created an extremely helpful video.

@drrajsree 7 ай бұрын

Thanks so much for your kind support! 🙏 I really appreciate hearing from you! Best wishes, RN

@frangaglio1269 7 ай бұрын

Best video! You know how to explain it well and the pictures work well with it.

@drrajsree 7 ай бұрын

Thank you very much!

@cindilacasa3291 5 ай бұрын

Awesome video!! I've shared it with a few of my family members that just dont understand what I"m going through. Thank Yo so much!!

@drrajsree 5 ай бұрын

Thanks so much for watching! 😊 Glad it was helpful.

@benpierce2202 6 ай бұрын

Brilliant, logical explanations. I've heard many vids on MCAS, methylation et al. This is the best. Thank you for doing your videos.

@drrajsree 6 ай бұрын

Thanks so much for your kind support! 🙏 I really appreciate hearing from you! Best wishes, RN

@evelindubravova3140 3 ай бұрын

I got MCAS post covid, my throat and mouth were ´burning´ for 8 months until I got on Cromolyn, its life saver. Also, Ketotifen helps me a lot and Quercetin. I wish it could just go away though. I had inflamed thyroid and still have pain in bones and joints, the only thing ever helped was Prednisone 40 mg. Still on my way to proper treatment, its been 4 yrs

@drrajsree 3 ай бұрын

I'm so sorry to hear this. I hope your health improves! Thanks for watching. Best wishes, RN

@virginiastephenson3086 Ай бұрын

Where to buy cromolyn?! It's not available in the US 😢

@evelindubravova3140 Ай бұрын

@@virginiastephenson3086 Im sorry, Im in middle Europe and have to buy in Austria or Czech republic. Maybe online?

@evelindubravova3140 Ай бұрын

@@drrajsree Thank you dear

@cindyrobinson1260 9 күн бұрын

OMG, I’ve been having burning mouth symptoms for over a year now and never tied it post Covid problems. I’m hoping I can find that supplement online, here in the US

@cookinmom35 6 ай бұрын

Amazingly helpful video! I was just diagnosed with Classical EDS today (which I was expecting). What I didn't expect was that my practitioner said in all likelihood I also have MCAS! So I've been prescribed H1 and H2 inhibitors plus Prevacid for a month and we'll go from there. This video explained things so that the average person can have a better understanding of what we've been experiencing so thank you so much for that. I'll also be sharing this video with my family members who I now believe are dealing with this as well!

@drrajsree 6 ай бұрын

Thanks so much for watching! 😊 Best wishes in your health, RN

@d.dimaggio322 6 ай бұрын

This should be mandatory for every Dr to watch and get educated on MCAS and histamine intolerance.. Thank you for a great video easily explained,I wish you lived in the San Francisco Bay Area.😊

@ElizabethMillerTX 8 күн бұрын

I have hEDS and have essentially put my mcas into remission. Don't settle.

@manjolaskendo4236 4 ай бұрын

Thank you Dr. Rajsree. This is the best information on MCAS i have found. Having MCAS i do find this video incredibly helpful. Thanks a lot for your hard work and information you shared. ❤🎉🎉🎉

@drrajsree 4 ай бұрын

Thanks so much for watching! 😊 Great to hear this video was helpful!

@maryk4717 2 ай бұрын

is mcas the same as cirs?

@drrajsree 2 ай бұрын

It's different. Thanks for watching.

@miamullins673 5 ай бұрын

Absolutely the best explanation in one video.

@drrajsree 5 ай бұрын

Thanks so much for watching! 😊

@tacocat8608 5 ай бұрын

Amazing video. Best one I've seen on the subject. Thank you for producing this. I wish I could get my doctor to watch it. I've seen nearly a dozen providers, including four immunologists, and none of them know any of this. I will definitely check out your store. I need to heal my gut. I react to almost everything. By the way, what are your thoughts on Black Seed Oil (Nigela Sativa)? Helpful for MCAS or no?

@drrajsree 5 ай бұрын

Thanks so much for watching! 😊 I haven't read much about Black seed being beneficial in MCAS.

@natachagauthier3376 7 ай бұрын

Hi Dr, this was a very great and complete video ( exposé). I just recognised myself and all the membres of my family. Unfortunately many doctors dont know thé mcas ans they must of thé Time get anoyed during thé consultation and just dismiss us. It is really difficult to find one that is knowledgeable in this area. Anyway i will keep surching until i find the help i need. Thank you very much for this Great video that i Hope will help Many of us suffering from MCAS . God bless you and your family

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊 I really appreciate your kind words and blessings.

@chippawa 3 ай бұрын

Thank you so much this video, this is the best ever informative video I've ever seen about MCAS. This is exactly explaining all of my symptoms and I'd experienced most of these symptoms without any diagnosis. I've visited Gastroenterologist, endocrinologist, PCP, cardiologis, pulmonologist etc. Lately I am getting allergy shots, lactose free , gluten free histamine free diet, H1 and H2 blockers. I am not suffering GIsymptoms like before. My unexplained diarrhea, colic pain , vomiting suddenly stopped after the second allergy shut. I still suffer deep muscle and joint pain after every allergy shot along with nausea, several times vomiting. I am more energetic than ever before. My allergy dr told me my allergies might be through mast cells.

@drrajsree 3 ай бұрын

Thanks so much for watching and best wishes in your health! 😊

@charlenesultana8862 6 ай бұрын

Thankyou so much! Your videos are so thorough and easy to understand ❤

@drrajsree 6 ай бұрын

Thanks so much for watching! 😊

@JuneHeffer 3 ай бұрын

A doctor I saw recently suspects MCAS and hEDS at the root of POTS for me. So until I’m able to work again and afford specialists and treatment, at least now I can attempt to avoid mentioned triggers and try supportive supplements to hopefully see some relief finally thanks to your comprehensive video. Thank you so very much!

@drrajsree 3 ай бұрын

Thanks so much for watching! 😊

@StephanieKaster-hw4bk 3 ай бұрын

This was exceptionally helpful. Thank you for sharing your knowledge!

@drrajsree 3 ай бұрын

Thanks so much for watching! 😊

@farhanqureshi1666 7 ай бұрын

Dear Dr.Rajsree , Black tea ,prickles inhibit DAO and thus triggers the MCAS.so tea and MCAS are mutually exclusive. Please discuss the role of DAO supplements ,dietary intake of organ meat like kidney which contain DAO. Vitamin B6 in form pyridoxal 5 phosphate 100mg really helps in mitigating symptoms since it involve in metabolism of histamine.benfotamine also has role in gut adhesion of cellular lining .thanks for making awesome video on this topic .regards,farhan

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊 Yes DAO supplements can help some people with histamine intolerance to better tolerate high histamine foods. I didn't mention it in the video because they are from porcine kidneys and are expensive and have limited efficacy. Often taking Digestive Enzymes can offer a more significant benefit. By healing the gut, a person is able to restore their own DAO production most times. Yes B6 is part of the methyl B complex that I recommended and is a co-factor for DAO and therefore can be helpful.

@rosssundberg5510 7 ай бұрын

@@drrajsreeI can’t seem to tolerate b vitamins (including methyl forms). I’m wondering if this means I should stay away from them or if it’s paradoxical.

@Vanilla2290 7 ай бұрын

Thank you for the Video! I think it's so helpful how you make your Videos and how you always have a step-by-step plan, cause you can feel really lost with all the information out there and I often get confused and that therefore really helps! I also love how you breakdown those diseases and how you complain them so easily that even a child could understand them! Thank you so much for your work!!! I also have MCAS and I really hope this can help me next to my other things I get from my doctor! :) Also I am from Europe and wanted to ask, if there's a way to ship your supplements to my country too? :) I also wanted to ask for maybe other topics for other videos: xsyndrom of loss of bile acids and xType A Gastritis (also if you have an ulcer cause of that and how to treat that. Normal medications can't really help there, cause theres already too little stomach acid, but because of the ulcer I also cant take betain, although I would need it, cause Im having really bad problems with digesting my food. Do you have there also some alternative recommendations and what someone can do than?) I have another doctors appointment this week again, but maybe you have some tips there too! Thank you again for your videos and I wish I could become one of your patient too! ;)

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊 We ship our supplements throughout the United States. Unfortunately, we do not ship to other countries yet due to challenges with shipping abroad. Hopefully someday! Thanks for watching! Best wishes, RN

@tsegeredatesfaye85 7 ай бұрын

Thank you Dr Rajsree l am lerning so match frome your video and l am very greatful that your sharing so much knowledge GOD bless you and your family 🙏🏾

@drrajsree 7 ай бұрын

Thanks for watching my new video Tess! Your kind words are always so uplifting! Appreciate your blessings and support always!

@judydoyle1845 3 ай бұрын

I've always had allergies here and there. A few years ago I started getting hatd with Anaphylaxis and that is brutal!! Swollen etc. but no one says how dang sick a person gets......loss of sight, total body weakness, throwing up, diarrhea, losd of voice, loss of consciousness. Im seeing an Allergist Immunologist the first of June. I have no idea what I'm so allergic too. I have Epi, Prednisone and liquid Benadryl with me all the time. I get so angry because no one seems to understand how sick. The ER and paramedics have been great though. When I learned the anaphylactic symptoms like sweating, tingling, overwhelming body heat and lip sweating.....I thought on crap, I've been doing this thinking it was related to my IBS! Now I know the "IBS" was a start of a reaction.........thanks for posting info.

@drrajsree 3 ай бұрын

Thanks so much for watching! 😊 I hope your health improves!

@irisvandijk570 2 ай бұрын

Hi Judy, Same here, and still figuring it all out, I think I got MCAS and histamine intolerance just realising a few days ago and this video again seems to back it up. Just seen a doctor (specialising in allergies..) and just got told i just have uticaria and edema. which only means swelling and are basically only symptoms.. that's all she gave me and wanting to prescribe anti-histamines. I read somewhere that anti-histamines is onlyl for short term and not good in the long-term. Also I just read from your comment that you use steroids. Please become aware of TSW. I've been through hell getting that from prednisone, only just after a few rounds. Best thing is to avoid steroids. It's not even worth the risk of getting TSW as it's extremely bad and will disrupt your life majorly. just wanted to let you know. All the best

@judydoyle1845 Ай бұрын

@@irisvandijk570 not doing Prednisone very often at all. This is a good Immunologist and Im impressed with her. She is looking at the Mast Cells and Thyroid. She doesnt believe its food related. Also, antihistamines will not stop Anaphylaxis at all. Two of my worst attacks I had Claritin in my system daily. Benadryl will not stop Anaphylaxis, only an Epi will stop the progression until medical care is given. It is given after the Epi. Its going to be a lot of testing and in the end there may be no answer, its the Idiopathic Anaphylaxis . Just keep the Epi or two by you at all times!!

@topchic7475 3 ай бұрын

Great video, thorough, informative and positive. Thank you 🙏🏻

@drrajsree 3 ай бұрын

Thanks so much for watching! 😊

@sourcehealing82 4 ай бұрын

This video is a miracle for me! Thank you so much.

@drrajsree 4 ай бұрын

Thanks so much for watching! 😊 I'm so happy to hear my MCAS video was helpful to you!

@ezvahedi1387 7 ай бұрын

thank you very very much . great video

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊

@kzl 2 ай бұрын

C'est très bien expliqué, merci, en France, les médecins sont ignorants... Je souffre d'un MCAS depuis 40 ans

@drrajsree Ай бұрын

Thanks so much for watching! 😊

@whoisender 2 ай бұрын

This was such an informative video. Thank you so much for your efforts. 🙏🏼

@drrajsree 2 ай бұрын

Thanks so much for watching! 😊

@funghouls5498 4 ай бұрын

Very informative and thoughtful presentation.

@drrajsree 4 ай бұрын

Thanks so much for watching! 😊

@katharinaolsson3809 3 ай бұрын

Hi I have reflux, hiatus hernia, astmasymtoms, dry caugh. My face and chest turn red(flushing) several times every day. And inside my mouth my chin swells. My brother died from cancer last year and since then I've been so afraid to get sick by my self. I went to the doctor to get some bloodtest done. Cromogranin A and 5-HIIA and they came back normal. I also did an CT of my neck, thorax, and abdomenal. No cancer was found. I wonder now if I can trust the tests and the CT ? My doctor doesn't think my symtoms has nohing to do with Histamin when I asked her about it. The only answear I get is it's becaus of trauma and stress. What do you think?

@drrajsree 3 ай бұрын

You might want to get a second opinion from another doctor.

@houseofroos 7 ай бұрын

Awesome video ! Do you find tinnitus to be a common or possible symptom of HI or MCAS?

@drrajsree 7 ай бұрын

Yes tennitus can be seen in both! I did come across in my research that sometime anti-histamine ear drops can help. Please check with your doctor. Thanks so much for watching! 😊

@christinal.suarez1838 Ай бұрын

Excellent video and info thanks!

@drrajsree Ай бұрын

Thanks so much for watching! 😊

@andreuxg Ай бұрын

Very well explained and detailed.

@drrajsree Ай бұрын

Thanks so much for watching! 😊

@VitalTransformationsLLC Ай бұрын

I ❤ your videos! Thanks to you & your team for making this content.

@drrajsree 27 күн бұрын

Thanks so much for your support!

@shehwardhuny1055 7 ай бұрын

Such an eye opener hat's off to you

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊

@agatakowalsky6809 2 ай бұрын

If someone takes betaine hcl/pepsin along with digestive enzymes, can they take histamine h2 blockers?

@drrajsree 2 ай бұрын

Yes! Thanks for watching.

@fitgirlflexis 4 ай бұрын

This was helpful, thank you!

@drrajsree 4 ай бұрын

Thanks so much for watching! 😊

@emteebee1872 3 ай бұрын

This is interesting. I first had dermatographism when I was 14. I’m 51 now and noticed it went away like 3-4 years ago. Around the same timeframe, I started getting itchiness all over my body like every 3-4 months. Do you know if dermatographism can go away and change into itchiness? It’s like I’m being bitten by lots of tiny bugs or being gently poked by needles that cause extreme itchiness. With that said, would you be able to tell me which of your products I can try? Thanks in advance!

@drrajsree 3 ай бұрын

Sorry to hear this. If I had to pick one product it would be Histamine Support. We get great feedback on this one for histamine symptoms like itchy skin. It's best taken at a dose of 2 capsules twice a day. Thanks for watching! You can shop for any of our supplements here: dr-rajsrees-public-supplement-store.myshopify.com/

@emteebee1872 3 ай бұрын

@@drrajsree thank you! I just ordered Histamine Support!

@Ruktiet 7 ай бұрын

I got cholinergic urticaria after either a polio vaccine, food poisoning in Thailand, chronic PPI use, or severe stress from my education, or due to any combination of these. Having a dual Campylobacter jejuni and Toxoplasma gondii infection from food poisoning triggered an extreme amount of additional strange symptoms on top of this. I’m quite sure SIBO, which I tested positive for, plays a role in this, either causal, or a result. Do you think it’s possible to calm the mast cells down in this case of a trigger which can’t be reversed. I mean, I can’t go back in time to avoid the triggers… and treating SIBO with rifaximin and prokinetics didn’t work. It came right back. what are your thoughts? Any input from anyone reading this would be appreciated!

@drrajsree 7 ай бұрын

Every individual is different. I believe there is always hope to heal the body. Finding and working with a knowledgable provider to guide you step by step would be very helpful. I do have a video on my herbal protocol for SIBO if you are interested: kzfaq.info/get/bejne/sK5xh858yeDSeXU.html&t=3s

@funny1048youtube 7 ай бұрын

I definitely have mcas, histamine intolerance, leaky gut, sibo, Mthfr. Should I just take all of the supplements you mentioned in the video?

@drrajsree 7 ай бұрын

I apologize I can't advise you personally on what to take. You're welcome to learn more about the supplements on my store and decide: dr-rajsrees-public-supplement-store.myshopify.com/

@mr.s.1324 7 ай бұрын

Thank your for this amazing video! If a person had SIBO / Dysbiosis / Leaky Gut prior to Long Covid, is it possible that these conditions lead to the development of long covid, because the immune system and mast cells where already triggered and weakened? Thank you!

@drrajsree 7 ай бұрын

Very possibly yes! 70% of our immune system is in our gut, so if there is gut microbiome dysfunction, this could weaken our ability to fight and overcome common viruses. Thanks so much for watching! 😊

@marie-francedemers3626 Ай бұрын

Wow thank you for these video. Very complete

@drrajsree Ай бұрын

Thanks so much for watching! 😊

@annesimpson2146 6 ай бұрын

I have MCAS. Is there an association between MCAS and sarcoidosis which I was diagnosed with 20yrs ago. I also have hypothyroidism.

@drrajsree 6 ай бұрын

I have not heard of an association between MCAS and sarcoidosis in my research. Hope your health improves! RN

@christinahurt7505 6 ай бұрын

Have you had any patients (or heard of cases) of myoclonus, chorea, dystonia or any other movement disorder caused by either POTS, MCAS, mastocytosis, SIBO, GERD, candida, EDS or any diseases/syndromes you mention in this video?

@drrajsree 6 ай бұрын

No I have not. Thanks so much for watching! 😊

@user-dv1nr9bd3z 3 ай бұрын

Hello Dr ,I just discovered your channel,so interesting! Just a gentle note,if I may:(again,thanks for the great infos) for me,struggling with mcas,me cfs,brain fog and dysautonomia,the little hand writing on the video is quite a strong signal and makes it a bit difficult to continue watching ,as I am sensitive to these quick stimuli,along with the music,as it is quite dense information requiring concentration.So maybe considering a gentler,quieter visual would be great! Just a thought.kind regards from the South of France

@drrajsree 3 ай бұрын

Wonderful to hear from you in France! My videos can also be listened to (like a podcast) if that would be better tolerated. But thank you for watching and for your feedback.

@umtum 4 ай бұрын

Hi Dr I live in the OC. How could I see you for a consultation? I have been dealing with what I believe to me MCAS and also digestive problems for the past 6 years. I was hoping you could work with me to find a solution.

@drrajsree 4 ай бұрын

I apologize I'm not taking new patients at this time. I hope some of the tips in this video can help you. To search for a functional medicine provider, please go to IFM.org Best wishes in your health, RN

@auteur55 3 ай бұрын

I am sure I have this. I was just diagnosed with EOE which I feel is tied to this? Do you think that’s possible?

@drrajsree 2 ай бұрын

EoE is generally true IgE allergy mediated so you definitely want to have and IgE food panel done. Some patients with MCAS also have true IgE allergies as well so it's possible.

@phillyphilly5508 7 ай бұрын

We check nearly every box in the video and are doing most of the “treatments” with not much success. How do we find someone great to work with around us?

@drrajsree 7 ай бұрын

Dr. Laurence Afrin is the doctor who wrote the book on MCAS and has a lot of experience. I don't know him personally but I did see he offers consultations: aimcenterpm.com/dr-lawrence-afrin/

@amberwest9478 4 ай бұрын

Try cutting out high oxalate foods. It made a huge difference for me with my MCAS.

@diyanvlogs5079 7 ай бұрын

Dr madam oregeno oil how to drink sibo patient... Water mix or

@drrajsree 7 ай бұрын

It comes in a capsule you swallow with water. You can learn more about it in this video covering my Herbal Protocol for SIBO, which you can find here: kzfaq.info/get/bejne/sK5xh858yeDSeXU.html&t=3s

@LM-pz5mu 6 ай бұрын

Hi , doctor Can I take iron supplements with ibs and sibo pain, will it make it worst?

@drrajsree 6 ай бұрын

Iron is often hard on the gut. You can try a low dose one to see how it affects you.

@christinahurt7505 6 ай бұрын

I have IBS, GERD, chrinic gastritis, SIBO and anemia. My dr saud to start 63mg of iron from ferritin daily. I knew I couldnt take the regular iron supplements so I researched it and found 65mg carbonyl iron w vit C. Been on it couple weeks with no additional abdominal/GI symptoms. Iron ferritin can cause nausea and constipation which is what my Dr told me to try. Not a very good idea if you already have a lot of GI issues.

@yanyperez7576 7 ай бұрын

I love your videos , you are the best ❤

@drrajsree 7 ай бұрын

Thanks so much for your kind support! 🙏 I really appreciate hearing from you! Best wishes, RN

@MichaelMerritt 3 ай бұрын

Thoughts on using low dose doxycycline as a mast cell mediator and calm over active microglia? Ie 20mg EOD for MCAS that seems specific to gut pain and neuro inflammation, very little histamine specific events, like rashes or allergies. But neuro inflammation after certain foods and activities.

@drrajsree 3 ай бұрын

I have not come across low dose doxycycline in my research on MCAS. Thanks for watching.

@karmenashikian2479 7 ай бұрын

I took a Gi map test and it shows high H pylori. Is that a good test to start treatment for h pylori or should I get a breath test?

@drrajsree 7 ай бұрын

GI Map uses the PCR assay for H. pylori which overdiagnoses the condition (false positives) in my opinion. You can confirm this with the stool antigen test available at most labs or the breath test.

@karmenashikian2479 7 ай бұрын

@@drrajsree I only know of the breath test at quest labs. But the breath test involves you to drink a certain liquid. Is this safe long-term side effects?

@qingdaogrrl Ай бұрын

MCAS has made me allergic to corn. Corn is in every vitamin supplement - either as magnesium stearate or cellulose capsules. Is the answer to get everything compounded??

@drrajsree Ай бұрын

So sorry to hear this. Yes unfortunately compounding is often a helpful option for MCAS patients.

@karmenashikian2479 7 ай бұрын

Every dr says to take each one H2 blockers. What are your thoughts on that?

@drrajsree 7 ай бұрын

Yes I mentioned H1 and H2 blockers under the treatment section. Thanks so much for watching! 😊

@hintutorial6629 2 ай бұрын

Hello Dr. I have 13month old baby boy. He suffering from this infection from his 4 month old age. Now i stopped medicine. Can i start cetirizine drops ?

@drrajsree 2 ай бұрын

Please discuss with his doctor. I apologize I can't advise on his health.

@pembreypaws1542 6 ай бұрын

How do I find an MCAS specialist in Wales UK?

@drrajsree 6 ай бұрын

Great question! Maybe search online? Best wishes, RN

@irmakalember9403 7 ай бұрын

Wow it seems like me. I always have pain. Chronic migraines divorce IBS I always have issues.

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊 Hope this video helps bring some insight.

@frangaglio1269 7 ай бұрын

What does an acquired disorder mean for MCAS and how is it determined to acquire MCAS opposed to acquire histamine intolerance? Thank you.

@drrajsree 7 ай бұрын

With MCAS there is a rise in the tryptase level during a flare and reactions are to many things other than foods (as seen in Histamine Intolerance). MCAS involves gene changes in Mast Cell Genes that are acquired by a trigger (stressor). Histamine Intolerance is often acquired due to gut microbiome issues that reduce production of the DAO enzyme.

@frangaglio1269 7 ай бұрын

@@drrajsree thank you.

@Karmazov 2 ай бұрын

@@drrajsree Dr. If the trigger or stressor is identified and removed than can you recover from MCAS ?

@2piecepapi 2 ай бұрын

How long can you take the Natural Antihistamine Doc?

@drrajsree 2 ай бұрын

A lot of my patients take it for months with no problems.

@codylyles54 2 ай бұрын

Quick question Doc! If I have MCAS due to SIBO, will curing the SIDO in turn cure the MCAS? Or will I have to do two different protocols? Any guidance or help would be greatly appreciated. My symptoms just started about a year ago but they are progressing pretty fast. Please and thank you 🙏🏼

@drrajsree 2 ай бұрын

I would address the SIBO first since gut healing is key in MCAS. Thanks so much for watching! 😊 You might also like my video on my Herbal Protocol for SIBO, which you can find here: kzfaq.info/get/bejne/sK5xh858yeDSeXU.html&t=3s

@codylyles54 2 ай бұрын

@@drrajsree thanks Doc! And I actually watched your sibo protocol video right before this one. Thanks for the reply and clarification. Keep pumping out these informative videos!

@patricianoll1229 3 ай бұрын

Every time i go to the doctor they thinks im crazy

@drrajsree 3 ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@adisumtiati693 6 ай бұрын

Doctor, i m a woman, a few thick hair grow on upperlip and jaw. What is the cause and how to get rid of them permanently through diet and lifestyle only.

@drrajsree 6 ай бұрын

Sometimes this is from high testosterone. You might like my video on PCOS: kzfaq.info/get/bejne/pdtxgqqEqJarhp8.html

@adisumtiati693 6 ай бұрын

@@drrajsree Thanks doctor.

@agatakowalsky6809 3 ай бұрын

What about hiper-IgE (HIES) the Hiob syndrome?

@drrajsree 3 ай бұрын

That would be different from MCAS. Thanks for watching.

@karmenashikian2479 7 ай бұрын

Dr what about H pylori. You did not address this. Most important how to get rid of h pylori?

@drrajsree 7 ай бұрын

Great question! My next video will be on H. pylori so stay tuned. Generally treated with antibiotics, but there are some herbal protocols available as well.

@ronm6585 7 ай бұрын

Thank you.

@drrajsree 7 ай бұрын

You're welcome!

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊

@user-yh3he6ly3w 5 ай бұрын

Thank you, doctor. I suffer from asthma and leaky gut problems. I eat only carrots and meat. I have an allergy to histamine, lectins, salicylate, thiol, phenol, sulfur, oxalate, and perhaps FODMAP. I am allergic to all herbs and additives. Supplements must be selected. Almost all of them sensitize me. I did an intestinal protocol with a practitioner, but the results were opposite. Supplements and their components irritate mast cells. They worked. With the biomesight laboratory. I live in Morocco. Do you work online? I hope you will work with me. What is the intestinal test that you work on?

@drrajsree 5 ай бұрын

Wonderful to hear from you in Morocco! Unfortunately I don't work online. Hope you can find a provider to help you. There are some on Institute for Functional Medicine (IFM.org) that may do telehealth consults.

@amberwest9478 4 ай бұрын

Check out KPV peptides and how they can calm mast cells.

@nitroe3242 2 ай бұрын

Does pollen cause flares? I've been so sick since spring started but all my symptoms are gi related

@drrajsree Ай бұрын

Yes it can. Hope your health improves.

@nitroe3242 Ай бұрын

@@drrajsree I see, do you accept patients that aren't in Cali?

@SailorYuki Ай бұрын

I've had issues since birth. Severe anaphylaxis multiple times, joint and muscle pain, fatigue. Hypermobile joints made me conclude that I've had hEDS since birth. That then developed into MCAS somewhere down the line and that led to my M.E. diagnosis. I'm still trying to get both hEDS and MCAS confirmed but keep getting dismissed. Funnily enough, one of my more severe allergies that showed up from nowhere disappeared after the Covid vaccines. I just got GERD diagnosed (after 5 years of suffering), but I'm allergic to all antacids.

@drrajsree Ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@kmonper7205 4 ай бұрын

what magnesium do you suggest to take at night?

@drrajsree 4 ай бұрын

We carry essential magnesium that is really popular. Thanks for watching! You can shop for any of our supplements here: dr-rajsrees-public-supplement-store.myshopify.com/

@malapammivlog 5 ай бұрын

Good

@drrajsree 5 ай бұрын

Thanks so much for watching! 😊

@warrenhennon9607 7 ай бұрын

Hello Dr. Is there a connection with Autism and Mast Cell disfunction?

@drrajsree 7 ай бұрын

Great question! I didn't come across that in my research, but I wouldn't be surprised if there was a connection.

@avgejoeschmoe2027 6 ай бұрын

@@drrajsree Strange thing Autism. I saw a review of a real good study connecting poor nutrition and the severity of autism. Poor nutrition = low vit D3, low magnesium, low..... The study even showed amazing improvements from getting essential vitamins up to good levels on the marginal autistic participants.

@jerryrodgers6760 2 ай бұрын

I have pots and long qt so I am taking ivabradine but then 2 weeks ago I got the hpv vaccine and this rash started coming up with bumps and bumps clumped together so I went to the doctors and they said I have mast cell activation,so they said the ivabradine is triggering it but i can’t go of it they said ill just have to live with it

@drrajsree 2 ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@yakoobyasseen2539 7 ай бұрын

Dr thanks for letting everyone know you have just nailed it from Johannesburg South Africa 🇿🇦

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊

@byrdma12 Ай бұрын

She described me perfectly

@drrajsree 27 күн бұрын

Thanks for watching. Sorry to hear this; hope your health improves!

@byrdma12 21 күн бұрын

@@drrajsree I am following the protocol and I believe it is working. Thank you for the work you do. Blessings.

@myberney 22 күн бұрын

Great

@drrajsree 22 күн бұрын

Thanks so much for watching!

@isabelisabel6670 4 ай бұрын

i heard a doctor say methylated b vitamins bind to histamine creating methylhistamine making the condition worse. What are your thoughts on this Dr.? what should we take with the B complex to avoid this. is this posible?

@drrajsree 4 ай бұрын

I have not found Methylated B vitamins to worsen the condition, rather only help.

@jalpari7117 7 ай бұрын

🙏💕✨ Gratitude

@drrajsree 6 ай бұрын

Thanks so much for watching! 😊

@qingdaogrrl 4 ай бұрын

I'm in mold detox treatment. I can't figure out what to eat! I'm losing my marbles.

@amberwest9478 4 ай бұрын

Try cutting out high oxalate foods. Mold actually increases oxalates in the body which then increases histamine. This made a huge difference for me.

@drrajsree 4 ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@qingdaogrrl 4 ай бұрын

@@amberwest9478 thanks!!! It's been impossible to try to determine between what I'm allergic to, a low histamine diet, and an anti candida diet. Rice felt like the only comfortable thing, but then my doctor was being very judgy saying they're eating too much sugar when we're trying to starve the mold. So low oxalate is really helpful. I figured out yesterday that I was allergic to the binder that my doctor gave me for mold instead of charcoal. And already feel better and now can actually figure out what to eat when I'm not having an allergic reaction to the binder. Thank goodness for these videos where it finally clicked when the doctor talked about having constricted airways and I realized I've been having trouble meditating and singing and that was the light bulb moment for me to be able to tell my doctor. Hey I think I'm allergic to this.

@hayd9785 4 ай бұрын

Does fexofenadine help this condition

@drrajsree 4 ай бұрын

It's an antihistamine (generic for Allegra) so yes it can help.

@balaprasadbadayale9941 2 ай бұрын

Super

@drrajsree Ай бұрын

Thanks so much for watching! 😊

@frangaglio1269 7 ай бұрын

Can histamine intolerance turn into MCAS?

@drrajsree 7 ай бұрын

Great question. I talk about Histamine Intolerance vs. MCAS in the video. No, generally Histamine Intolerance does not turn into MCAS. MCAS is different in etiology (genetic predisposition + trigger that causes mutations in mast cell regulatory genes).

@jackeygibney893 Ай бұрын

I feel as if I’m allergic to everything. Well a lot of things. I began to react to the sensitive skin arm and hammer detergent etc. I have always had sensitivity and allergies etc but after Covid it got rediculous . After I had that insane cytokine storm so many more things flare me up. I took an Uber and just stepping into the vehicle I got a severe allergic reaction to the “little trees “ air freshener. Unscented stuff is used in my house. I can’t even clean with most cleaners anymore and I used to be able to. One thing though is it’s not the hot as you were mentioning about hot showers. It’s the cold. The heat is almost like a soothing feeling. It helps with pain, allergies you name it. Along with the tree (only prarie naturals) shampoos etc. but the cold causes a release of histamines etc. In fact the cold causes physical pain if my skin comes in contact with it. Ugh I live in Canada too which is not ideal. I’ve never heard of mast cell syndrome till recently.

@drrajsree Ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@karmenashikian2479 7 ай бұрын

Hi Dr I would love your help. How can I get an appointment with you?

@celticsunise4ever 7 ай бұрын

The MD may not be taking new Pts but check her website.

@drrajsree 7 ай бұрын

@karmenashikian2479 7 ай бұрын

@@drrajsreeI’m sad to hear. Not all functional dr’s are knowledgeable in mcas.. I really need help. I have attempted to do this on my own but had no success.

@citymuse1484 7 ай бұрын

@@karmenashikian2479 Unfortunately it is quite challenging... there are a few options including UCI integrative center and restoration healthcare.

@citymuse1484 7 ай бұрын

@@karmenashikian2479 RHC specializes in chronic conditions, including MCAS. There are a few others but as you've mentioned it's difficult to find a qualified provider.

@bumpscross7238 Ай бұрын

How do I heal my gut?

@drrajsree Ай бұрын

Please check out my vide on Leaky Gut

@truescotsman4103 Ай бұрын

I just discovered I'm afflicted. I have all of the symptoms noted all the time I've had this problem all of my life. I used to get hives and difficulty breathing when I was a kid. I remember the first time it happened I was exposed to poison ivy the real one not poison oak. I was a kid and a poison ivy had caterpillars all over it and I played with them for a few minutes and had a very serious mast cell activation event. Ever since that day my immune system was altered. All related to my allergies that presented when I was about 6 and I'm now 59. It's destroyed my vision by about 45. I've always had perfect vision and for no known reason I need a 2.25 prescription now. My main symptom is swollen watery eyes and brain fog. Varying degrees of inflammation all over my body. Constant stomach upset. Basically the most severe symptoms because I'm so sick and I've never treated the disease. One medication that helped me was Doxycycline. I've been diagnosed with somatoform disorder. I started taking Cetirizine, Vitamin C and Bromelain.

@drrajsree Ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@beatz3279 4 ай бұрын

Anyone used Toxaprevent to help this.

@drrajsree 4 ай бұрын

Thanks so much for watching! 😊

@aluna_m888 Ай бұрын

I have MS, since 2008. I’m convinced that my Mast Cells are causing me symptoms that I got confused to ME, chronic fatigue and many others. Where is the light at the end of my tunnel???!!! 😂😂😂

@drrajsree Ай бұрын

I'm so sorry to hear this. I hope your health improves! Best wishes, RN

@RashelleLindquist 9 күн бұрын

Have you noticed a relation to Mcas and endometriosis?

@drrajsree 9 күн бұрын

There is a correlation between endometriosis and SIBO, but I haven't heard of a correlation of MCAS with endometriosis.

@Squids_Vlogs Ай бұрын

I thought oregano oil destroyed both good and bad bacteria in the gut?

@drrajsree Ай бұрын

In my experience, I have not seen oregano oil adversely affect the gut microbiome.

@audreyhepburn8633 7 ай бұрын

Great video ! Unfortunately I react to almost all supplements so it makes it very difficult to heal.

@drrajsree 7 ай бұрын

Thanks so much for watching! 😊 Sorry to hear that. Not sure if you're able to find a compounding pharmacy that can make supplements for you without fillers. Best wishes , RN

@illuminationgoddess3 Ай бұрын

I rarely drink, just need CoQ 10 Thank you.

@drrajsree Ай бұрын

Thanks so much for watching! 😊

@juliemorris8952 5 ай бұрын

Have a combination of your blogs, Fatty Liver disease , think it's chocolate only one brand , IBS-C which high fibre makes worse , MCAS ( not tested but told that's what's wrong ) , gerd/hiatus hernia , so now oils , fats , gastritis, fibromyalgia. Some allergies/sensitivity prior strokes / encephalitis, after several courses of same antibiotics , my body decided enough, since , can't take any antibiotics, many meds, foods, pollen, body / air sprays, perfumes, real Christmas trees, soaps, washing powders, it often causes either sore throat, sneezing, inflammation in bowel, stomach, itchy skin, rashes . What help is good for one isn't good for others. I have to be as well as I can for disabled son as well as my own disability from stroke, partially blind, seizures, muscle pain. Any suggestions would be much appreciated, thank you. I have read your blogs, they are good but again , one that's great for one may not be for others. I also reacted to Loratidine. It's so hard to deal with this, thanks again, Jules

@drrajsree 5 ай бұрын

I'm sorry to hear this. It's best work work with a functional medicine provider for more personalized guidance.