I have never in my life seen a medical video that is good as yours, truly professional.

Beautiful animation. I wish more biological videos were made like this.

The best medical video I've ever seen ....

When I wanna introduce Alzheimer's disease to my friends or other people, I recommend them come to this video. It's a wonderful material suitable for all people even they aren't researchers in this field.

A beautiful animation to summarise what's happening in Alzheimer..

My granddad is currently in the later stages of this. I've come to accept it as inevitable, but its still hard, partially because I never fully understood it at the neurological level. Thank you for uploading this.

For patients and caregivers, this is the most insightful and well-accessible video I've watched about the pathological bases of dementia. There is now increasing evidence that tau is present at sub-detection thresholds before amyloid though. Hopefully with the development of in vivo tau imaging markers in the next couple of years, we will all get a better grasp of the temporal sequence.

my dad died of the disease. Please cure it so no one else and their families has to go through that suffering.

I freaking swear they need to make videos like this for A&P, diseases, and medication effects. I would pay good $$$ for these!!!! Videos like this are the only way I can truly understand the process of things!!!

Yess try do our best to make it into a understanable way our ways in Scenice so everyone can enjoy to

This is the one time that I embrace technology, a deeper understanding, very educational and a compassion for the mysteries of human mind, body and soul, superb 🙏

Also this is the best animation for AD on YT.Don't even waste your time trying to look for more. Thanks for sharing LECMA.

By far the best presentation of AD I have seen. The way you integrated the beautiful music with the animation, together with the narrative made it beautiful to watch. Thank you.

real great animation and explanation even an alzheimer patient could understand

What a clip? Completely flawless... Awesome.. Awesome awesome and thousands of awesome

Very good video summarizing the neuropathogenesis of AD, however, I think it's essential to highlight the hyperphosphorylation of tau proteins

This is an excellent explanation of how the brain changes occur and Alzheimer's disease I would urge you to watch it several times because it has many many features that are important to understand as far as the details of how the disease happens. One addition that I would like to add is that most of these changes are actually initiated by the autoimmune process in the brain.

Amazing video depicting the pathological process, very insightful

Simple and clear explanation of the disease, thanks!

Great video, it makes it easy to understand

Very good and well explained! gosh, how animations help us understand such a complex phenomenon like that one.. thanks for sharing! :)

so far the BEST animation of pathophysiology Ive seen here on youtube!Thumbs up!:)

Excellent video. Perfect animation and the music is so soothing. The person narrating is awesome!

This is the scariest thing i have ever seen...

I've read from a few articles that amyloid beta plaques activates an enzyme called kinase and kinase has a phosphate group on itself. The kinase then phosphorylates the Tau protein and that is why Tau protein detaches itself from the microtubule.

The best medical video I've ever came across.

Excellent!! Easyto follow and to understand.

Brilliant way to tie together other alzheimers videos here on KZfaq.

I am school student and you made my mind just blow you are great with your explanation

Thank you for a wonderful synopsis of this most debilitating disease!

Thank you so much for the beautiful animation

My father died of this. He was 63. I have witnessed every stages of it to his very last breath. Worst experience ever

Thank you! This video made me understand better about AD and it is going to help me to write my thesis! Greetings from Northern Italy.

This film is very beautiful and easy to know key points of Alzheimer's disease. Thank you!

Very Useful animation and the descriptions are also very helpful..

so good and simple understood, with importants informations, thank you

Great video indeed, complexity explained in such simplicity that it gives us a great baseline to build on... Thanks heaps.

wht a awesome animation which includes emotional background sounds.........Which tends people to attract more towards ''Psychiatry'''

This 6 min video lecture slove my all doughts quickly so thank u so much 😊👌👍👌😊👌👌😊😊😊

Scary, yet great presentation.

magnificent animation! great job on raising awareness of Alzheimer's !!!!! hope that scientists find a cure for this disease!

Very informative, and I enjoyed the music as well. Would like to know the artist.

amazing, i would never understand or even interesting to "peek out" about alzheimer if i never watched this. thank you

Very informative video. Thank you so much.

Oh my god! Thank you for this! I was sitting in patho yesterday and I swear I heard crickets! This helps to clear it up so much! Thank you!

Alzheimer's disease/Dementia, is a dreadful and cruel illness,it is currently affecting 850,000 people,And still continues to affect more. I went to visit My Grandmother,after she was diagnosed. Having spoken to her and seeing how she was affected,It distressed me deeply. I am very close to My Gran,So this has hit me hard. The last time I saw her prior to that,never one had it ever crossed My mind that she would ever get struck down by this illness. She has always been a strong woman and such a lovely lady with a kind and generous heart,One of pure gold come to think of it. She would dance around the house waltzing to Andre Rieu , She always made me smile and has always been there when I needed her,Even if it was just on the end of a phone. I do love My Gran,and it is horrible to see a loved one in such a bad way, Knowing that this debilitating illness is ravaging them from the inside. My mother,who is 3rd of my Gran's daughter's , tries to show bravery,But she is hurting and I know it, The thing is it's never their fault or yours, They are in their own world,completely unaware of how their loved ones are affected by seeing them that way, It's just I have heard or seen situations where people caring for an Alzheimer's patient have lost their temper and snapped,and naturally it's very hard to cope in that situation,But the patient is not to blame. I am dreading the day My gran forgets me,Becomes hostile, and is no longer herself indefinitely! ,There isn't a day goes by when she isn't on my mind, And after seeing how she was at the time, I went back to pick up My girlfriend from her Mother's place, and upon embracing her,I sobbed, It hit me so hard, Seeing one of My family no longer themselves. My girlfriend suggested I should organize a charity event. So I'm in the process of it now and pretty much almost done! I want to do everything I can to raise funds and awareness. From 27th May 2017, I will be hosting/performing a live show in aid of Alzheimer's UK charity. I will be working closely with Zoe Baggot who deals with Birmingham's side of things,I will be playing a mixture of Electronica,Dubstep,Chillout,Dance and Industrial,I know it is to early to be sure,and It may not be to everybody's taste,Or too far out for some to travel, and Donate, find time to listen to some of the music on there.There will be a live stream of the event so for those who live across the pond or other places you will get to see it .Also the music i have written for this live performance will be released on an album and 100% royalties are offered out to Alzheimer's UK There will be stunning visuals,Lazers and more, And the live stream will be broadcast globally on You Tube From the Coldstream Pub in Birmingham. I will be doing 3 Events in total to try to raise at least £1000 or over. I know I can't save My Gran,But I can try to save others in the future.

What an excellent video - as informative as it is artistically composed. Thank you.

Such a beautiful video that actually made me emotional. Thank you

My Grandma has Lewy body dementia. This video made me feel really sad,as she were quite bad today

This was a great video. It was very educational and the animation was very detailed.

Thanks for uploading this video. I am a student. It helps me a lot.

Imagine walking from room to room, but not knowing why you did so when you get to the next room. Being unable to even recognize words as words anymore, but having to read them letter by letter, and even then having to read the sentence over and over to grasp its meaning. No longer knowing how to spell names of family members. Short term memory at times being completely nonfunctional. Suddenly at times having no connection at all to time nor place. Suddenly not recognizing even your own neighbourhood. Unable to recognize quantities greater than two, which makes it almost impossible to take any meds in quantities greater than two. When three or more pills are in the palm of your hand, the quantity is unrecognizable to you. Then eyes taking up to 2 hours to respond to change in light intensity. What makes it even worse, is when the doctors misdiagnose you. What makes it even more unforgivable, is that it was a self diagnosis that provided the correct diagnosis, despite being one step away from being a vegetable. It took me 8 years to fight my way back, to no longer having a body that was as stiff as a 2 by 4, to relearn again, although I never did relearn how to write, other than write my signature.

Excelente video muy claro y conciso, además súper bien explicado.

Amazing animated videos... This is the best video that I have ever seen..

Thanks for the working staff, the most beautiful animation I have ever watched 💓💓

You are creative ,,, very informative 💜

awesome work on details on both content and graphical explanation

The Best & Simple Explanation Ever.... Thank You

Wat a video😍.... Chanceless.... Best visual ever👌👌👌

This scientific video is really good. Awesome 3D video, easy to follow and understand. Great job!

Thanks a lot, this is the best video I found about this topic.

elegant animation, thanq guyz

How Awesomatic animation is! Superb

Excellent demonstration n animation

Thanks for making this video, it's really informative and good-quality.

Thanks for this video today I hope to continue for other disease by this way of explanation

The video before this is better in describing the progression of this monster disease

Beautiful animation.and superb explanation

Que vídeo espetacular ❤️❤️❤️

Excellent visual explanation. Thank to the advancement of Animation

Superb video for medical students 👌👌

Great animation. It is like that i wish.

this video is a jewel

Amazing video.

I saw a Ted Talk where a lady Dr said she got great results with Coconut oil for her husband who was suffering early onset dementia. Any news on that study?

Great explanation thank you so much

simply amazing video !!

This is fantastic. So glad I watched it.

Awesome ...thanx maam

U r sooo goood. U r welly educated Dis was very helpful. Do upload such vdos more. Thank u

great great great video .. The graphics ..

best one.......come on 😃👌👍

amazingggg graphics....superb explanation...👍

Amazing video with sad facts. Thank you.

best video... no words to explain how much i like

what a fantastic video, brilliant graphics.

Thank you. Exellent video. Let's hope in sience and resercers❤

Reactive oxygen species (ROS) may contribute to the beta-amyloid buildup. A study found good sleep now can prevent Alzheimer's in the future by reducing ROS.

Thank You! for such a great video...

Este vídeo es fantástico

Very attractive video

This video is amazing. Thank you so much!

I wander how Charleston Heston and Glen Campbell -singer musician developed AD. They were active and athletic. Was there diet the culprit?

you caused I understand clearly... thanks... good job and keep going...

This is terrifying

Please can you correct the captions/subtitles, they are incorrect in quite a few places. Cheers

I find it really helpful ! Thanks !

Great work! thanks for uploading this :)

Great video, but the music is like a lullaby, I almost fell asleep because of it.

Excellent