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What actually determines the RDW is the width of the red cell volume distribution curve.
To calculate RDW, use the following formula: RDW = (standard deviation of MCV ÷ mean MCV) × 100.
In case of morphologic anisocytosis, RDW, which is normally 11-14% will increase to about 15-18%.
RDW is of great benefit in two clinical scenarios;
(1) In patients with microcytic anemia, when the differential diagnosis is between iron deficiency and thalassemia. In thalassemia, the small red cells are generally of uniform size with a normal small RDW, Whereas in iron deficiency, the size variability (and therefore the RDW) is large.
(2) High RDW may suggest a dimorphic anemia which occurs when a chronic atrophic gastritis can produce both vitamin B 12 malabsorption to produce macrocytic anemia and blood loss to produce iron deficiency.
All of hematology videos (more to come) are here: • Hematology/ Oncology
My FAVORITE BOOK to study Pathology and pathophysiology for step 1 USMLE is Goljan, you can check it out here: goo.gl/9ojg6M
My favorite book for internal medicine is Harrison's, check it out here: amzn.to/2A7UEdj
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In my opinion, the fastest way to raise your score on USMLE is flashcards.
There is a program called firecracker, it’s really fun, they made flashcards for you and they repeat questions based on YOUR OWN specific knowledge of each one, they may be offering DISCOUNTS now mbsy.co/gcHHP
Don’t forget to check my recommended collection of the best medical books out there www.amazon.com/shop/medicosis...
This set of flashcards covers “the most likely diagnosis”… a must have for any exam, I have gone over them more than 3 times to review and refresh, that’s how good they are. goo.gl/FZqTsn
If you want flashcards for pharmacology, these cards rock, trust me, I have tried them myself, goo.gl/Hxdr9y
As of flashcards for Diagnostic tests, these are especially helpful for USMLE step 2 and COMLEX step 2, goo.gl/awWm7B
Last, here is a set of flashcards about "physical findings” which is great for USMLE step 1, step 2CS, CK or step 3 goo.gl/pJqw5Z
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