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►👨‍🏫💊Antibiotics Lectures: www.medicosisperfectionalis.c... ... Check out my brand new "Electrolytes" course at www.medicosisperfectionalis.c... and use the PROMO code: ELECTROLYTES50 to get a 50% discount. ► Right Now! You can get access to all my hand-written hematology video notes (the notes that I use on my videos) on Patreon...There is a direct link through which you can view, download, print and enjoy! Go to / medicosis Liver cirrhoisis, hypoxia (hypoxemia) and Platypnea-Orthodeoxia.
Learn what is the reason behind the nomenclature...
Pulmonary arteriovenous malformations are found in patients with liver cirrhosis, probably due to the absence of a hepatic factor.
So, liver Cirrhosis will affect the blood vessels in the lungs by 2 different mechanisms:-
1) Absence of a hepatic factor which leads to arteriovenous malformatins in the lung.
2) Production of Nitric Oxide (NO) which is vasodilatory in effect, which will dilate the arteriovenous shunts in the lungs, increasing the chance of blood passing quickly without sufficient gas exchange, which furtherly worsens the problem.
Ventilation perfusion mismatch will occur (Shunt Physiology)
Diagnose the disease with Contrast ultrasound or technicium albumin. Contrast ultrasound is more accurate, so it is used as a confirmatory test.
My FAVORITE BOOK to study Pathology for step 1 USMLE is Goljan to study Pathology , you can check it out here: goo.gl/9ojg6M
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To get the pathophysiology in more detail, watch this: • Hepatopulmonary syndrome
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