Paracetamol Overdose/Poisoning Patient Treatment & Management in Emergency, Toxicology Lecture USMLE

No video

Paracetamol Overdose/Poisoning Patient Treatment & Management in Emergency, Toxicology Lecture USMLE

Рет қаралды 57,397

Күн бұрын

Paracetamol Overdose/Poisoning Patient Treatment & Management in Emergency, Toxicology Lecture USMLE
Paracetamol aka Acetaminophen or Tylenol commonly available in markets as panadol tablet is very common used tablet with which overdose patients commonly present to emergency department. Paracetamol poisoning patients are managed in emergency department with N-AcetylCysteine which is an antidote for paracetamol overdose. Paracetamol/Acetaminophen overdose or poisoning is a highly tested topic from toxicology lecture in usmle step 2 ck exams.
Chapters:
(0:00) Intro
(0:17) Paracetamol Overdose level
(1:03) Mechanism Paracetamol Poisoning
(1:53) Signs Symptoms of Paracetamol Overdose
(2:58) Investigations
(3:45) Treatment/Management
(4:32) Sideffects of N-acetylcysteine
(5:16) Paracetomol Overdose in Children
(5:42) Liver Transplant Criteria
(6:28) Summary
SUBSCRIBE TO MEDNERD FOR MORE INTERESTING VIDEOS
Emergency Medicine Lectures Playlist :
• Emergency Medicine Lec...
TOXICOLOGY/POISONING LECTURES: • Toxicology/Poisoning L...
ATRIAL FIBRILLATION: • ATRIAL FIBRILLATION (A...
#paracetamoloverdose #paracetamoloverdosepatients #paracetamoloverdosetreatment #paracetamoloverdosemanagement #paracetamolpoisoningmechanism #paracetamolpoisoningmanagement #paracetamolpoisoninglecture #paracetamolpoisoningtreatment #paracetamoloverdosechildren
paracetamol,paracetamol overdose emergency medicine,paracetamol overdose usmle,acetaminophen overdose usmle,acetaminophen poisoning,tylenol overdose,toxicology lectures

Пікірлер: 74

@MedNerdDrWaqasFazal Жыл бұрын

IMPORTANT CLINICAL POINTS: If patient has ingested >150mg/kg of Paracetamol, then treatment depends on timing of presentation 1. if patients presents within < 1 Hour of ingestion : Give Activated Charcoal(1g/kg max upto 50g). then wait for 4 hours post ingestion and send paracetamol levels, if still elevated (100mg/L at 4 hours) give NAC. 2. if patients presents within 1-3 Hours of ingestion : Activated charcoal has no role. Wait for 4 hours post ingestions and send paracetamol levels (It means that if patient took paracetamol at 12pm, presented to hospital at 2pm, then doctor should wait for 2 hours and send paracetamol levels at 4pm), if still elevated (100mg/L at 4 hours) give NAC. 3. if patients presents within 4-8 Hours of ingestion : Don't Wait, take blood immediatly and check Paracetamol levels, if elevated Start NAC 4. if patients presents after 8 Hours of ingestion: Give NAC straightaway, after giving NAC send blood sample for paracetamol levels. 5. If time of ingestion unknown: Give NAC DON'T FORGET TO CLICK ON SUBSCRIBE BUTTON 😊 FOLLOW ME ON Instagram: instagram.com/docwaqasfazal/ Facebook: facebook.com/Drwaqasfazal

@bahiachibi895 Жыл бұрын

Thank u for the video it is awesome

@radhikasharma2211 5 күн бұрын

hey I take 6 paracetamol at one time . Now I am suffering from vomit so what I have to do

@Medicos-knowlageble 3 ай бұрын

You are such a quintessential teacher your way of teaching is pulchritudinous.

@aishahuma2097 3 ай бұрын

Thnku so much sir, no one explained me like this... Amazing sir. It's very helpful for us at phc level for Medical officers

@alfiyafiya6757 2 жыл бұрын

Excellent presentation ,helps so much

@nisekkhatiwada1303 Жыл бұрын

A very informative lecture sir ❤️ We subscribers are very grateful getting teacher/enabler like you sir ❤️🇳🇵 Much love from Nepal sir 🇳🇵

@draishwaryarobbin2049 2 жыл бұрын

Your videos are really helpful boss… hope to get time to upload a video daily as i wait for whats coming next.. :)

@MedNerdDrWaqasFazal 2 жыл бұрын

So Nice of you Dr. Aishwarya Robbin 😊

@ExtensiveMedicine 23 күн бұрын

Nice video!

@lakshmanayb5009 2 ай бұрын

Tqsm sir

@avgjoedoc9629 9 ай бұрын

This is such a useful lecture, Sir.

@shashankmishra5254 2 жыл бұрын

Again Superb Sir.,🙏🙏

@junaidnazir2618 4 ай бұрын

I hope u will help me and give me right direction

@lianbeletty7977 2 жыл бұрын

Nice

@ZahidHussain-ht4tw 2 жыл бұрын

Thanks sir.. very nice video..

@salmanjavid295 Жыл бұрын

respected sir

@evolvingdaily7762 2 жыл бұрын

Sir pl need little help, you said in symptoms that metabolic acidosis develop due to hyperventilation, I don't get it!

@MedNerdDrWaqasFazal 2 жыл бұрын

I am very sorry. It was by mistake. Metabolic acidosis develops due to lactic acid buildup not by hyperventilation. Thank you for your response.

@evolvingdaily7762 2 жыл бұрын

@@MedNerdDrWaqasFazal thanku sir, I'm preparing for part 2 exam fcps, your videos are v helpful!

@MedNerdDrWaqasFazal 2 жыл бұрын

Wish you all the best. May God ease everything for you. I am very glad to hear that. 😊

@Leoadiil Жыл бұрын

You are the first Indian man 😍🫡 I have ever listened to with great pleasure and happiness and your explanation is very beautiful may god bless you😍❤

@blessedslave Жыл бұрын

Bio says he's from Pakistan

@junaidnazir2618 4 ай бұрын

Hi sir.I have question how can we different post hepatic jaundice ,pre ,post haptic jaundice symptoms rather then paracetamol poisoning bcz the syomtams almost some seen daily practice

@rajeshroy306 10 ай бұрын

Crystal clear explanation sir

@Mkhan-tl3yx 3 ай бұрын

Sir cotraindication of nacetylcystin plus when to strt methionin please

@cavidmammadov2987 2 жыл бұрын

Thanks for video. I have a question in term of treatment. If the patient has diabetes can we use saline infusion instead of glucose at the same dose like glucose

@MedNerdDrWaqasFazal 2 жыл бұрын

Yes you can give it in half saline. 0.45 saline

@jaushwanthD-pu1dh Жыл бұрын

Paracetamol poisoning is slow way to so iam trying it with alcohol. Hope my journey will be fast

@Rick_Cleland Жыл бұрын

It's not, and I'm speaking for first-hand experience.

@radhwanabdulla6806 Жыл бұрын

Thanks

@jennelynjoymacugay1913 Жыл бұрын

If 45 mins passed and patient ingested 15 maximum strenght of acetaminophen whatbis the PRIORITY antidote or gastric lavage ? I saw questions that have diferebt answers 15 yrs old and a Child ?

@idkwhattonameit8359 Жыл бұрын

Thx doc ! Can someone explain what it meant by over 1 hr then over 4 and 16 hrs ?

@Ajsavage. 6 ай бұрын

Have u took premium subscription for living ?

@ramjibanyadav28 11 ай бұрын

great ❤

@aadrshclinic9062 2 жыл бұрын

Upload videos on intra mascular injection with complication

@MedNerdDrWaqasFazal 2 жыл бұрын

Sure Chetan I will. 😊

@jennelynjoymacugay1913 Жыл бұрын

Gastric lavage 1st or the antidote? What is priority

@shivamsharma-mm2mc 2 жыл бұрын

You are amazing ✨

@MedNerdDrWaqasFazal 2 жыл бұрын

Thank you Shivam 😊

@misbahumar4577 Жыл бұрын

👍👍👍

@dumb2pro Жыл бұрын

Sir yesterday i have mistakenly taken calpol 600 and algina 500 both 3 times a day sir what should i do would it affect me plzz reply sir i am too much scared about it

@nourwaleed6780 Жыл бұрын

I need a source about the paracetamol towards children

@chotiooo9151 Жыл бұрын

What is the difference between N acetyle cystien and Acetyle cystein please explain doctor

@junaidnazir2618 4 ай бұрын

Good question

@TillyHarris Жыл бұрын

Hi, my friend took 20 paracetamols and experienced extreme liver pain and vomiting/nausea etc. This was months ago and she has had no treatment. What do I do?

@animeraven976 Жыл бұрын

did she took that in 1 go

@aimanmalik4411 6 ай бұрын

@animeraven976😂

@jeethu8032 6 ай бұрын

Please help. Accidentally I gave 2ml paracetamol to my 10 months baby by mistake. Doctor prescribed 1.2 ml. Do I have to worry? Now its 2 and half hours and he looks normal and very active

@souravmajumder5807 15 күн бұрын

Don’t worry….bt next time u should be more conscious….pcm is hepatotoxic when u consume it for long time with overdose….bt incase of child does is very important….so don’t do that again

@souravmajumder5807 15 күн бұрын

Bt yes.if u intake large amount of pcm at a time …it can also damage your liver

@syedahsan538 2 жыл бұрын

Sir i have a question when do we start treatment with NAC ... do we wait for paracetamol levels.. or just start the treatment..???

@MedNerdDrWaqasFazal Жыл бұрын

Syed Ahsan If patient has ingested >150mg/kg of Paracetamol, then treatment depends on timing of presentation 1. if patients presents within < 1 Hour of ingestion : Give Activated Charcoal. then wait for 4 hours post ingestion and send paracetamol levels, if still elevated give NAC. 2. if patients presents within 1-3 Hours of ingestion : Activated charcoal has no role. Wait for 4 hours post ingestions and send paracetamol levels, if still elevated give NAC. 3. if patients presents within 4-8 Hours of ingestion : Don't Wait, take blood immediatly and check Paracetamol levels, if elevated Start NAC 4. if patients presents after 8 Hours of ingestion: Give NAC straightaway, after giving NAC send blood sample for paracetamol levels.

@williamsagunbiade105 2 жыл бұрын

Thanks for the helpful video, pls what is the place of Measuring serum paracetamol level and the timing before the use of NAC?

@MedNerdDrWaqasFazal Жыл бұрын

If patient has ingested >150mg/kg of Paracetamol, then treatment depends on timing of presentation 1. if patients presents within < 1 Hour of ingestion : Give Activated Charcoal. then wait for 4 hours post ingestion and send paracetamol levels, if still elevated give NAC. 2. if patients presents within 1-3 Hours of ingestion : Activated charcoal has no role. Wait for 4 hours post ingestions and send paracetamol levels, if still elevated give NAC. 3. if patients presents within 4-8 Hours of ingestion : Don't Wait, take blood immediatly and check Paracetamol levels, if elevated Start NAC 4. if patients presents after 8 Hours of ingestion: Give NAC straightaway, after giving NAC send blood sample for paracetamol levels.

@raninetawate 8 ай бұрын

I ate more than 30 tablets but nothing happen

@kksga5476 Жыл бұрын

You did not discuss the graph

@sujeetshah4129 10 күн бұрын

NAPQI sir its not NAPQ1.

@Leoadiil Жыл бұрын

👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻

@nisekkhatiwada1303 Жыл бұрын

Sir what is the toxic paracetamol dose? A. >150mg/kg/day B. >200mg/kg/day I'm a little bit confuse about this...

@armouredspartan8639 6 ай бұрын

>150mg/kg/day

@Tulips313 11 ай бұрын

لا خطأ الباراستمول مضر وفيه جرعة محددة له و هي اكبر من 150 ملي غرام لكل كيلو غرام للشخص البالغ يعني اضرب الوزن في 150 تطلع الجرعة السامة من الباراسيتامول اللي تأثر على الشخص و تسمم الباراسيتامول يؤدي الى تسمم الكبد وفشله، فمعلومتك خطأ أن الجرعة الزائدة غير مهمة ويا ريت ما تنشر معلومات طبية خطأ لمتابعينك خصوصا اغلبهم يعتمد على كلامك و ممكن يتألم وياخذ باراسيتامول اكثر من المطلوب ويفشل كبده ويموت واصلا الجرعة التي لا يسمح بتجاوزها للبالغين هو اربعة غرام خلال 24 ساعة و البنت اخذت ٦ خلال ساعة يعني تجاوزت الجرعة التي ينصح بها اصلا انا طالبة طب و هذا الكومنت للفائدة، يا ريت تثبته حتى المتابعين يدرون اكيد انت ما كنت تدري بعد 🌱

@nirobminar606 2 жыл бұрын

I am dying from overdose and nobody cares🙂

@MedNerdDrWaqasFazal 2 жыл бұрын

nirob minar, I am sorry that you feel this way. You can share it with me.

@nirobminar606 2 жыл бұрын

@@MedNerdDrWaqasFazal I took 12 paracetamol of 500 mg yesterday and I vomited after one hour and then Somehow I managed to sleep after that waking up in the morning I realized that it will damage my liver and I will be a burden for everyone I told my sister and she told me drink tamarind juice to vomit and I drank that after 12-14 hours later of overdose and I vomited but nothing came out except that tamarind juice now 24 hour’s have passed but I am unable to visit doctor as I am a student of class 10. I am having pain in my lower stomach. If you can tell me any solution please help me I need help.

@nirobminar606 2 жыл бұрын

@@MedNerdDrWaqasFazal I have sent you a message on your page Sir please help me if you can

@MedNerdDrWaqasFazal 2 жыл бұрын

You may see your doctor. And tell your guardians about this situation. Your doctor may run a few tests to see if liver is doing fine.

@nirobminar606 2 жыл бұрын

@@MedNerdDrWaqasFazal Thank you for the suggestion sir. Assalamualaikum.