As someone living with Sickle Cell Disease, I can vouch for how extremely painful and dangerous it can be. Thanks to The Infographics Show for spreading more awareness.

My appendix ruptured when I was 4 years old, my Dad rushed me to the hospital and was immediately told by the surgeon that if he had waited 15 more minutes to bring me to hospital, I would have already been dead and as it was, I only had a 50% chance of surviving the surgery. Obviously I did survive, thanks to my dear Dad. Rest In Peace Dad, I love and miss you so very much! 😓

"We've saved you from heart attack sir. Here's your bill." * Sees the bill. Dies.

“If you’re wealthy enough to go to the emergency room” that’s one of the most American sentences ever

Lol when he said if you don’t move your shoulder in long period of time I started moving my shoulders 😂

"the pain only last for few minutes" :D "Because you'll be dead afterwards" D:

This proves that life is a never ending circle of pain

"Warning: The final entry is very graphic!" The animations are cartoons.

Stubbing your toe and feeling that sensation of no pain for 0.43 seconds.

My fear of the dentist lead to almost 12 years of the most agonising pain a human can feel. Nothing compares to tooth decay.

"If you ever been wealthy enough to go to the emergency room to seek treatment..." That is upsetting.

My appendix ruptured when I was 19 years old and can confirm it was AWFUL. I had been feeling generally unwell with a mild fever and fatigue and headaches for a few days, but thought it was just a cold or other virus. It started to progress to almost flu-like symptoms, exhaustion, worse headaches, and what I would describe as muscle aches and pains all over my stomach area, sides, and lower back. I took Tylenol and assumed it would pass on its own. Then one morning, I woke up and was in pretty bad pain specifically in the right side of my lower abdomen area and when I told my parents, my mom assured me it was just a bad period. But this was just SO different and my period had passed a few weeks prior. I went to the ER and the doctor originally suspected a kidney infection or a UTI that was becoming a kidney infection. He soon started pressing on my stomach area and my sides to examine and figure out what was happening. He pressed down pretty firmly on my right lower abdomen, and I SCREAMED and began crying. The pain felt incredibly sudden, sharp, almost a burning or searing pain. They quickly arranged for an ultrasound. My already extremely inflamed appendix had burst inside of me (I assume from the pressure of the examination.) Within 40 minutes, I was started on painkillers, IV antibiotics, and rushed into emergency surgery for them to remove the appendix and clean out my abdomen of all the fluids from the appendix. It was a terrible experience but I’m honestly glad it had burst in the ER and under the immediate care of a doctor and not while I was at work or driving or something. People, listen to your body. Your body does not give you these signals for no reason!

My dad got Appendicitis around 6-7 years ago. He described it as a cat was scraping your intestines open. He fortunately had his appendix removed before it burst.

I got shot in the neck. The pain still wakes me up at night even though I feel no physical pain

I’m so glad you put sickle cell on this list there are not enough people that know about it and know how horrible it can truly get for us I’m really happy people are starting to recognize how serious of a problem it is!

My cousin has sickle cell DISEASE , asthma, insomnia, he’s currently over 11 and is a warrior.

Not so fun fact: Some women think appendicitis are period cramps and ignore it because of that

I had appendicitis. Worst month of my life.. as a grown man i literally shed tears because of the pain

The most painful thing I have suffered was pancreatitis, losing two thirds of my pancreas. Thank goodness for the doctors & nurses that cared for me at The London Hospital in Whitechapel. You saved my life and for that you have mine and my family's thanks.

As someone who has had appendicitis and gotten his appendix removed, I can say that it is the most painful thing I’ve ever experienced. I’m just glad we got it early. Others in my family haven’t been so fortunate and got really sick from their ruptured appendices

Existing is the most painful thing in the world. But yet... it's the best

My dad died of appendicitis, and it breaks my heart to know he died in so much pain. He was truly so terrified of the doctor, he just laid in bed hoping to recover miraculously. I wish I had done more to comfort him. I’m not sure what else I could have done.

I almost died... Its not fun. Edit: TAKE CARE OF YOURSELF EVERYONE. THATS WHAT THE DEVIL DOESN'T WANT U 2 DO!

Appendicitis caused me so much pain for days. The issue is, I had no symptoms other than the pain. The common ones are nausea and vomiting, fevers, and just general malaise. Didn’t get any of it. Just the pain. After days I knew I had to go to the hospital, where they confirmed that I did in fact have appendicitis. I was 15 at the time, and my local hospital didn’t have a pediatric surgery unit, so I had to be transferred and wait overnight for surgery. The pain was UNBELIEVABLE. After the surgery, I was not properly cleaned out and had to go back to the hospital with a 106° fever after discharge. Absolutely miserable

Infographics: warning graphic images Me: yay can’t wait Infographics: shows absolutely nothing graphic at the end Me: throws phone across room

the most painful feeling humans can feel is both side of their pillow isn't feel cold.

The most painful thing a human can feel is burping after you’ve had soda and the carbon dioxide rushes through your nose.

My brother had appendicitis AND got sepsis after the surgery. This was very close to Christmas, and I'm glad he made it home in time to celebrate with us.

but stepping on a lego brick is at the top of the list right

I instantly started moving my shoulder around hearing about frozen shoulder 😂

I'm 25 with osteoarthritis affecting all joints. I also suffer with fibromyalgia. I've been battling both since 18. Took years to get a diagnosis. I have allergies to NSAIDs (all forms of Ibuprofen). Getting relief is a struggle. Finding a balance between what's too much vs making sure I'm not doing too little is a struggle. Anyways, I’m glad to see Arthritis on here. Its so painful.

That’s weird, I don’t see heartbreak on this list :(

As someone who has had appendicitis, I can confirm it is by far the most painful thing I have ever experienced.

The pain when you find out someone close to you dies is the worst pain ever smh

I have extreme pain almost constantly. Having TMJ (a jaw issue that can lead to head pain, jaw joint pain and locking, ear aches, and finger aches (at least for me)), IBS (irritable bowl Syndrome) which happens in both constipation and diaherria for me, and painful period cramps that make you cry in pain (and I have PCOS, didn't have a period for three years and got hit with a 2 week one with heavy flow this year) :') I can handle it a bit more if they hit at seperate times, but sometimes I get hit with all three if I'm off my meds which is often because I have to see a doctor for more of some. Muscle relaxers lead to periods, can't really control my diet currently so I eat trigger foods a lot which makes my stomach hurt often. It can't compare to these others things, but it's the most painful stuff I've been experiencing.

I just happened to stumble upon this video. I think it's a great video! I was wondering since this is part 4, have you covered trigeminal neuralgia? It's symptoms are life altering and the pain is so absolutely unbearable that people have committed suicide just to make it stop.

“I like you as a friend” This gotta be #1

Stepping on a lego

My hard labour was so bad that I truly believed there was something wrong and that everything from the waist down was coming off! Now thats pain!

I’ve been suffering from endless kidney stones since a teenager, the pain is indescribable

"if you don't have a second heart attack from the massive amount of debt your about to be in" *laughs in free health care*

“If you’ve ever being wealthy enough to go to the emergency room” if that aint the most american statement 😂

6:58 i can't be the only one that thought there was dirt on my screen

I loved that music loop !! Really well made !!

I’ve had a frozen shoulder. I had to do the painful stretching and it took four years to get better and six to be completely better. I need to add to this that the most painful part only lasted a few months and after that it did start getting better but it was about five years before I got full functionally back. I’m completely fine now so there is hope. It just takes time 🙂

People that can't feel pain: So anyway, I started laughing.

*Heart attacks are one of the most painful things ever!* Women, who's period cramps can be as painful as a heart attack: Wow, I must be strong.

My younger brother was diagnosed with arthritis when he was seven he is eight now and is fighting it with confidence. It really hurts him but he quite likes the attention 😂❤

Paper cuts. That millisecond where you know you're giving yourself one but can't do anything about it.

I dont know if this counts, but a crown fell off while drinking dr pepper today, exposing the root to very cold, very bubbly soda. I swear my life flashed before my eyes.

This video makes me wanna eat healthy & exercise to avoid all of these health issues!

Wow. I’ve had both the frozen shoulder and dozens of kidney stones (complete with 3 surgeries to remove the ones that were too big to pass). 10/10 can confirm both are excruciating.

Seeing the title: This is gonna be a neat video Whatching the video: Uncomfortable over entire body

The doctor who removed his own appendix without any pain killers is on a list of biggest badasses in history And chimpanzees in the wild are fighting back...goes to show you humanity's impact on the environment

That so true about sciatica. It got so bad I told the er doc to either find out why my leg hurt or cut it off. Thankfully they found the cause

I have experienced frozen shoulder (due to humerus fracture surgery) and sciatica at the same time. But for some reason I am glad to know these are one of the most painful things one can physically feel. Would not want even an enemy to go through these pains.

The heart attack made me sad… how I lost my dad…. Over a month ago now. I knew he had chest pains few times. Until he had another one that was the actual heart attack. Makes me Sad to think he did feel pain 😔😔 all I know he’s in a whole better place no pain. Just in peace 😔🙏🏽

I'm at such a genetic disadvantage, there are heart attacks in my family and my mother has rheumatoid arthiritis, and every member of my family has suffered appendicitus which is great.

I got sciatica about 6 years ago. One of the solutions I was treated with was an epidural injection in the spine, since I had a degenerative disk. I haven't had sciatica pain since.

sciatic is something i suffered with as a teen. i didn’t know i had it till the pain got so bad that i couldn’t play soccer anymore. and that sneeze thing is true. the way i got rid of it was some intense physical therapy for about 3 or 4 months

0:20 Frozen Shoulder 1:38 Heart Attack 2:41 Sickle cell disease 3:49 Arthritis 4:49 Sciatica 6:00 Appendicitis 7:43 Chimpanzee Attack

rolling ankle when walking hitting your shin with a scooter having a karen teacher waking up early and not being able to go back to sleep

I've had sciatica due to a herniated disk. It comes & goes at least once a year, but when it does, it's an absolute pain. I also had my appendix rupture when I was 13. Felt so awful, went to the ER only for the so called "doctor" to tell my mom & I that it was "food poisoning" mind you, I'm not one that cries for pain, but I was in tears that night. He refused to do anything else, so we had to go home. Appendix ruptured that night around 4am. Around 4ish pm, 12hrs later I remember waking up with a really bad fever, pain so bad that I couldn't even stand, sit or walk. It was over 12hrs since it had rupture & the surgeons (my family told me) had to talk extensively whether to perform surgery right there & then, or wait a few hours/days - cos my body already had too much poison from the rupture. Very long story short, all the surgeons, docs, & nurses told my family that there was a 90-95% chance I wouldn't make it & to just be ready... They all acknowledged the miracle. And here I am today, about to celebrate my birthday next week, & I thank God first & foremost & that amazing surgeon that I'll never forget. 🙏🏻 I was in the hospital & house rest for a little over two months, but man, the pain was unbearable. I'd rather the sciatica pain 5xs more, than to feel a ruptured appendix again.

THE DARK HUMOR IN THIS IS AMAZING. I LOVE IT HAHAH

When I was 13 I had a piece of steel split my eye in 2. I’m turning 45 and I can still describe the pain. I’ve injured myself or the years but that pain will always haunt me.

The Heart Attack entry made me sniffle. DMX suffered a heart attack and passed away today. RIP Ruff Ryder

When I was younger in the ER, my mom met another mom who was there with her little girl. Her little girl was screaming she was in so much pain, from a mass sickle cell die-off like you mention in this video. She was 10 years old, and she was given -- wait for it -- 75 milligrams on Dilaudid before the pain subsided. A "normal" does is between .5 mg and 2 mg. I deal with bowel obstructions more often than most because of the bowel surgeries I've had as a child, and I refuse to be given more than 1 mg of that stuff because more than that will make me hallucinate. I can not imagine the pain Sickle Cell patients have to endure!!!

had my appendix rupture a couple weeks ago and the pain was horrible. feels like a sharp burning pain on the right side of your stomach. every movement i made hurt. everything. got released from the hospital after about 5 days and had to go back in because i couldn’t keep food down, had a fever, and kept throwing up. they never even figured out what was wrong but my best guess is that my drain had a clog in it and the abscess from my appendix was spreading around ny stomach. i got discharged and was forced to go in again since some of the abscess had made its way into my right lung and given me a pneumonia type feeling. could only take about 1/4 of a breath. crazy experience

"And try not to have a second heart attack when you realise how much debt you'll be in" *Laughs In European*

The most painful experience I’ve ever had was living in financial doom. My brother had the Brugada syndrome and it cost my family hundreds of thousands of dollars for treatment. As immigrants, we didn’t have health insurance, so it wiped out both my savings and retirement accounts including our college funds and home equity which put us in a lot of debt. I managed to come in contact with a financial advisor who helped me grow my finances in the right stocks to invest in and I’m happy to say that my I and my family are living debt free today! 🥳🎉🎉

Drowning is one I died when I was 7 or 8 I was dead for 7 minutes but I remember hearing myself scream for help and I could hear everyone around me but they couldn’t hear me. Then darkness, the type that you wanna walk up but your at peace. I remember how amazing it was to be within the dark idk why but it seemed to be guiding me.

I have had juvenile arthritis from my earliest memory to even now sometimes, 23 years. It's horrible at times. When I was little I was terrified of rain or storms or really anything that changed it from sunny because my legs and arms would hurt to the point I could not move and I'd have to be carried to the bathroom to be put in a tub of the hottest water I could stand. I remember sitting hours in the tub because it was my only relief of pain. I had tried heating pads, meds, you name it I had tried it. I couldn't hardly do anything. I finally got to the point where I started to grow out of it and now it's mainly just when a major cold or warm front moves through. I still go get in the bathtub to relief pain but it's not as horrible as it used to be.

Endometriosis is extremely painful! I’m surprised it didn’t make the list.

My appendix burst when I was on a cruise ship. Excruciating doesn’t even begin to describe it. This was 19 years ago and I still remember it like it was yesterday. I had the stomach pains at first and the “doctor” on the ship said that it was an ear infection and said rest would do the trick. The next day I woke up and started vomiting like never before. I eventually was puking pure bile and it ruined my throat and mouth. I couldn’t walk and I could barely think I was is so much agony. I was constantly just yelling and screaming until I passed out again. Thankfully my aunt was also a doctor and convinced the crew to let her talk to the captain. I guess they got to shore in time and took me straight to the hospital. I woke up when they were doing the ultrasound where they had to PUSH on my stomach and that was the pain I remember the most. Pure rage. There’s no adjectives to describe that pain. Luckily I had a great team of surgeons and they got all the exploded pieces out and everything inside of it. Very lucky to be alive. 1/10, would not recommend.

I’ve was diagnosed with rheumatoid arthritis at 19 years old. I’ve always been really active to help but I can’t imagine how it will age with me.

"Try not to have a second heart attack", thanks for that buddy, really insightful.

I've have had a burst appendix before, so severe that the doctors needed to remove a portion of my intestines and a portion of my colon..was the most excruciating pain I've ever felt in my entire life

I can tell you personally, the “power washing” your insides after having your appendix burst is, there is no other word but excruciating. It was worse than the pain from the inflamed appendix, which admittedly was still horrible. But I ended up at a hospital that took hours to decide that my appendix needed to come out- so it of course burst before they got to it. Then, after thinking the hard part was over, I had to have my fresh foot long incision (that was trying to close up & heal) literally ripped open everyday so they could sponge out inside my abdomen with iodine.... I actually became despondent and nearly suicidal knowing I had to go through it all over again the next day. And the next.... in other words- I would suggest not letting that happen to yourself, you know if you can possibly help it

Wow I've had sciatica, 4 herniated discs, sneezed caused paralysis, 3 spinal surgeries causing neuropathy in both feet and arthritis destroying my right hip requiring total replacement due, as well as DVT forming a massive pulmonary embolism neccesitating implant surgery of an IVC filter. I also have had 2 kidney stones, a torn shoulder rotator cuff, been bitten by a rattlesnake once, a brown recluse spider once and black widows twice, (One of which I was dehydrated at the time, and the experience of your body needing to swell and not being able too is level 10 pain.) I also had a traumatic incident during my 3rd spinal surgery which consisted of L3-4-5- S1 and T11-12 with a rib removed where a nurse forgot to administer the morphine drip and when they woke me up in the middle of the surgery to have me stand up to make sure they'd corrected the paralyzed damage, I got to feel the sensation of Air contacting my spinal cord. The pain was so intense it made sound! All my senses cross merged and I went insane screaming . It took them 2@10cc demeral & 3@10cc morphine to stop me from screaming. I would've sold my childrens souls to get that pain to stop. Finally, after being prescribed opiates over the last 25 years, I stopped taking pain pills cold turkey last April 2021. Shakespeare wrote in Hamlet , when the ghost of his father appeared to him saying, "Were I not forbidden to reveal the secrets of my prison house... I could a tale unfold which lightest word, would harrow up thy very soul" This is pain I know. All enhanced by my being an empath.

I had saciate 2 times on a cruise, it was terrible but I slowly adapted to it and it is long gone now.

I would say that number 1 is the loss of your grandma, from my personal experience.

I got diagnosed with Arthritis at 14, and I’m so happy to see this on the list. It isn’t a walk in the park

Constipation contractions is the equivalent to having a baby and I’ve never even had a baby. The pain scale got to 10/10 one time, another time I felt like puking and I felt salvia pooling in my mouth and throat. I’ve had chronic constipation for years but up until the recent months have I realized it could be linked to my poor diet but I haven’t done much about it yet. Anyways though I have to go through that at least once a month (not a metaphor for period).

Sciatica....just had a 5 week battle with that. The pain....running down my leg.....was absolutely incredible. I had every tooth in my head pulled with nothing but novocaine. Needless to say, that was an extremely rough experience. But, no doubt, I'd do it over 20xs before a 2nd round with my most recent battle with sciatica. Literally the most pain I have ever felt in my 47 years of life.

Did anyone else start moving their shoulders around as soon as they heard of frozen shoulder?

"Try not to have a second heart attack when you realize how deep in debt you'll soon be" *Laughs in non-Murican*

As someone with arthritis I can relate to the pain a lot

I've had something very similar to frozen shoulder... Extremely painful Thank God I'm from the UK and we have the amazing NHS

Arthritis, yep. Sciatica, yep. As my dad always said, “old age isn’t for sissies.”

The most painful thing that can be experienced? Existence itself.

I have RA for many yrs and now disabled at 50 due to my condition. Nice list of have a few others on list frozen shoulder is also a symptom of menopause

I have polyarticular juvenile idiopathic arthritis and can confidently say that it’s by far the most painful thing I have ever experienced. Imagine that anytime you moved your joints at ALL, they were ripped apart from the inside out, and you will have some idea of the pain, and I appreciate the spreading of awareness for conditions like mine very much. However, I am a bit irritated that there was little indication that young people can have arthritis- it’s an autoimmune condition that anyone could have.

When you said the last one was gonna be really graphic I was expecting real pictures

I have PCOS and sometimes it literally feels like my organs are exploding inside of me. The pain is so bad I swear, get a fever, nearly throw up, can’t move, and struggle breathing. I’m constantly afraid I have appendicitis but it’s usually just cysts on my ovaries.

I have arthritis and sciatica from getting Lyme disease. It’s beyond painful. When I had bacterial meningitis and gall stones, that was the absolute worst pain I’ve ever had!

Last year I was in the hospital for suicidal ideation. There were no rooms available due to COVID and there was a line of us in beds in a hallway. I stayed 2 days in the hallway. My 1st night I was by a man who cried out in pain begging for help or death. I complained to nurses as my anxiety was extremely high for him. They basically told him to shut up and moved him to the opposite hall. I felt so bad for him! It still breaks my heart thinking of that poor man. Nurses said he had sickle cell disease. 💔

Getting a boulder thrown at you for trespassing in my woods has got to be somewhere on the pain list

I’ve had 2 kidney stones, they aren’t very fun...

I have had over 60 surgeries - primarily due kidney stones. Pain has been my constant friend for most of my life. Also I have gall pain. I lost my right kidney due to stones. That surgery recovery was brutal. I have had pancreatitis 4 times over 2 months. I have a hiatal hernia. Those are extremely pain

Tore my shoulder at the Rugged Maniac…the pain before surgery was fierce and 9 yrs later it bothers me daily.